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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Tim Sands
Welcome to BMC Bioinformatics published by BioMed Central
BMC Bioinformatics is an open access journal publishing original peer-reviewed research articles in all aspects of computational methods used in the analysis and annotation of sequences and structures, as well as all other areas of computational biology.
BMC Bioinformatics (ISSN 1471-2105) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Thomson Reuters (ISI) and Google Scholar.
BMC Bioinformatics 2009, 10 :120
Reconstruction of ancestral genomes with algorithms that estimate genome rearrangements is easier for multichromosomal versus unichromosomal genomes, and most of the theoretical issues with the combinatorial optimization problems of genome rearrangement have been resolved.
BMC Bioinformatics 2009, 10 :110
Two new data-driven normalization strategies for high-throughput real-time quantitative PCR data directly correct for technical variation and offer advantages over existing normalization methods, which rely on comparisons with standard housekeeping genes.
BMC Bioinformatics 2009, 10 :83
'Automics' is a new open-source software package for integrated spectral processing and analysis of nuclear magnetic resonance-based metabonomic datasets, which would otherwise require the use of several separate programs.
BMC Bioinformatics 2009, 10 :66
Patterns of gene expression indicative of cervical cancer can be detected using approximate entropy analysis of microarray datasets to identify genes displaying minimum variation in control tissue versus maximum variation in cancerous samples.
BMC Bioinformatics 2009, 10 :46
Text retrieval algorithms that search full-text articles in paragraph-sized segments ("spans") consistently find more relevant articles than searching either whole articles or abstracts alone, and a combination of full texts and spans gives the best results.
Volume 10 Suppl 5
Proceedings
Toronto, ON, Canada. 20 July 2008
Volume 10 Suppl 4
Proceedings
Philadelphia, PA, USA. 3 Volume 10 Suppl 3
Proceedings
Napa Valley, CA, USA. 30 October 2008
more info ]
Methodology article
Incorporating functional inter-relationships into protein function prediction algorithms Gaurav Pandey, Chad L. Myers, Vipin Kumar BMC Bioinformatics 2009, 10 :142 (12 [Abstract ] [Provisional PDF ]
Methodology article
Robust MS quantification method for phospho-peptides using 18O/16O labeling Claus A. Andersen, Stefano Gotta, Letizia Magnoni, Roberto Raggiaschi, Andreas Kremer, Georg C. Terstappen BMC Bioinformatics 2009, 10 :141 (11 [Abstract ] [Provisional PDF ]
Research article
Estimating parameters for generalized mass action models with connectivity information Chih-Lung Ko, Eberhard O Voit, Feng-Sheng Wang BMC Bioinformatics 2009, 10 :140 (11 [Abstract ] [Provisional PDF ]
Database
eCOMPAGT - efficient Combination and Management of Phenotypes and Genotypes for Genetic Epidemiology Sebastian Schoenherr, Hansi Weissensteiner, Stefan Coassin, Guenther Specht, Florian Kronenberg, Anita Brandstaetter BMC Bioinformatics 2009, 10 :139 (11 [Abstract ] [Provisional PDF ]
Software
PCOPGene-Net : Holistic Characterisation of cellular states from microarray data based on continuous and non-continuous analysis of gene-expression relationships. Mario Huerta, Juan Cedano, Dario Pena, Antonio Rodriguez, Enrique Querol BMC Bioinformatics 2009, 10 :138 (9 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
On finding minimal absent words Armando J Pinho, Paulo J S G Ferreira, Sara P Garcia, Joao M O S Rodrigues BMC Bioinformatics 2009, 10 :137 (8 [Abstract ] [Provisional PDF ]
Database
Infrastructure for the life sciences: design and implementation of the UniProt website Eric Jain, Amos Bairoch, Severine Duvaud, Isabelle Phan, Nicole Redaschi, Baris E Suzek, Maria J Martin, Peter McGarvey, Elisabeth Gasteiger BMC Bioinformatics 2009, 10 :136 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
CURE-Chloroplast: A chloroplast C-to-U RNA editing predictor for seed plants Pufeng Du, Liyan Jia, Yanda Li BMC Bioinformatics 2009, 10 :135 (8 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Validating subcellular localization prediction tools with mycobacterial proteins Daniel Restrepo-Montoya, Carolina Vizcaino, Luis F Nino, Marisol Ocampo, Manuel E Patarroyo, Manuel A Patarroyo BMC Bioinformatics 2009, 10 :134 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Software
SDRF2GRAPH - a visualization tool of a spreadsheet-based description of experimental processes Hideya Kawaji, Yoshihide Hayashizaki, Carsten O Daub BMC Bioinformatics 2009, 10 :133 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Three dimensional shape comparison of flexible protein using the local-diameter descriptor Yi Fang, Yu-Shen Liu, Karthik Ramani BMC Structural Biology 2009, 9 :29 (12 [Abstract ] [Provisional PDF ]
Research article
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays Joshua S Bloom, Zia Khan, Leonid Kruglyak, Mona Singh, Amy A Caudy BMC Genomics 2009, 10 :221 (12 [Abstract ] [Provisional PDF ]
Research article
A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila Li Wang, Zhidong Tu, Fengzhu Sun BMC Genomics 2009, 10 :220 (12 [Abstract ] [Provisional PDF ]
Research article
Correlation of expression profiles between microRNAs and mRNA targets using NCI-60 data Yu-Ping Wang, Kuo-Bin Li BMC Genomics 2009, 10 :218 (12 [Abstract ] [Provisional PDF ]
Research article
Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analyses Albert Mulenga, Rabuesak Khumthong, Katelyn C. Chalaire BMC Genomics 2009, 10 :217 (12 [Abstract ] [Provisional PDF ]
Software
Bump time-frequency toolbox: a toolbox for time-frequency oscillatory bursts extraction in electrophysiological signals Francois B Vialatte, Jordi Sole-Casals, Justin Dauwels, Monique Maurice, Andrzej Cichocki BMC Neuroscience 2009, 10 :46 (12 [Abstract ] [Provisional PDF ]
Research article
On the functional diversity of dynamical behaviour in genetic and metabolic feedback systems Lan K Nguyen, Don Kulasiri BMC Systems Biology 2009, 3 :51 (11 [Abstract ] [Provisional PDF ]
Research article
MicroRNA signatures predict estrogen receptor, progesterone receptor and HER2/neu receptor status in breast cancer
Aoife J Lowery, Nicola Miller, Amanda Devaney, Roisin E McNeill, Pamela A Davoren, Christophe Lemetre, Vladimir Benes, Sabine Schmidt, Jonathon Blake, Graham Ball, Michael J Kerin Breast Cancer Research 2009, 11 :R27 (11 [Abstract ] [Provisional PDF ]
Research
Insights into the regulation of intrinsically disordered proteins in the human proteome by analysing sequence and gene expression data Yvonne JK Edwards, Anna Lobley, Melissa M Pentony, David T Jones Genome Biology 2009, 10 :R50 (11 [Abstract ] [Provisional PDF ]
Research article
Comparison of the transcriptomes of American chestnut (Castanea dentata) and Chinese chestnut (Castanea mollissima) in response to the chestnut blight infection Abdelali Barakat, Denis S DiLoreto, Yi Zhang, Chris Smith, Kathleen Baier, William A Powell, Nicholas Wheeler, Ron Sederoff, John E Carlson BMC Plant Biology 2009, 9 :51 (9 [Abstract ] [Provisional PDF ]
Featured articles
5 November 2008
