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Editor-in-Chief Melissa Norton, MD
Biology Editor Penelope Webb, PhD
In-house Editor Scott Edmunds
Welcome to BMC Pharmacology published by BioMed Central
BMC Pharmacology is an open access journal publishing original peer-reviewed research articles in aspects of the discovery, design, uses, effects, modes of action and metabolism of chemically defined therapeutic and toxic agents.
BMC Pharmacology (ISSN 1471-2210) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE and Google Scholar.
Featured articles
BMC Pharmacology 2009, 9 :6
Human astrocytoma cells treated with the antipsychotic drug haloperidol show increased mRNA expression of QK1, a gene previously identified as a candidate gene for schizophrenia.
BMC Pharmacology 2009, 9 :3
Treatment with dimeticone blocks the spiracles of headlice but does not cause instant asphyxiation - instead the lice die slowly as water loss through the spiracles is impeded, causing physiological stress and occasionally osmotic rupture of the gut.
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Research article
Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models Nancy Lee, Chelsey L Woodrum, Alison M Nobil, Aubrey E Rauktys, Michael P Messina, Sandra L Dabora BMC Pharmacology 2009, 9 :8 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes Rong Shi, Chuan-Chin Huang, Robert S Aronstam, Nuran Ercal, Adam Martin, Yue-Wern Huang BMC Pharmacology 2009, 9 :7 (15 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Haloperidol changes mRNA expression of a QKI splice variant in human astrocytoma cells Lin Jiang, Peter Saetre, Elena Jazin, Eva Lindholm Carlstr BMC Pharmacology 2009, 9 :6 (31 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Preferential uptake of the non steroid anti-inflammatory drug diclofenac into inflamed tissues after a single oral dose in rats A Schweitzer, N Hasler-Nguyen, J Zijlstra BMC Pharmacology 2009, 9 :5 (16 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Bioinformatic characterizations and prediction of K+ and Na+ ion channels effector toxins Rima Soli, Belhassen Kaabi, Mourad Barhoumi, Mohamed El-Ayeb, Najet Srairi-Abid BMC Pharmacology 2009, 9 :4 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
The mode of action of dimeticone 4% lotion against head lice, Pediculus capitis Ian F Burgess BMC Pharmacology 2009, 9 :3 (20 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
AICAR activates the pluripotency transcriptional network in embryonic stem cells and induces KLF4 and KLF2 expression in fibroblasts Luigi Adamo, Yuzhi Zhang, Guillermo Garc BMC Pharmacology 2009, 9 :2 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Conformational changes in James T McLaughlin, Sean C Barron, Jennifer A See, Robert L Rosenberg BMC Pharmacology 2009, 9 :1 (13 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000 Zhan-Guo Gao, Kai Ye, Anik BMC Pharmacology 2008, 8 :20 (12 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Substituted trans -stilbenes can inhibit or enhance the TPA-induced up-regulation of activator protein-1 Lorraine M Deck, Lucy A Hunsaker, Amanda M Gonzales, Robert A Orlando, David L Vander Jagt BMC Pharmacology 2008, 8 :19 (10 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Short report
Inhibitory coupling between inhibitory interneurons in the spinal cord dorsal horn Charalampos Labrakakis, Louis-Etienne Lorenzo, Cyril Bories, Alfredo Ribeiro-da-Silva, Yves De Koninck Molecular Pain 2009, 5 :24 (12 [Abstract ] [Provisional PDF ]
Research
Low affinity glucocorticoid binding site ligands as potential anti-fibrogenics Carylyn J Marek, Karen Wallace, Elaine Durward, Matthew Koruth, Val Leel, Lucy J Leiper, Matthew C Wright Comparative Hepatology 2009, 8 :1 (11 [Abstract ] [Provisional PDF ]
Research
Cyclic GMP protects human macrophages against peroxynitrite-induced apoptosis Catherine A Shaw, David J Webb, Adriano G Rossi, Ian L Megson Journal of Inflammation 2009, 6 :14 (7 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
Existing plaques and neuritic abnormalities in APP:PS1 mice are not affected by administration of the gamma-secretase inhibitor LY-411575 Monica Garcia-Alloza, Meenakshi Subramanian, Diana Thyssen, Laura A Borrelli, Abdul Fauq, Pritam Das, Todd E Golde, Bradley T Hyman, Brian J Bacskai Molecular Neurodegeneration 2009, 4 :19 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Sexual attraction enhances glutamate transmission in mammalian anterior cingulate cortex Long-Jun Wu, Susan S Kim, Xiangyao Li, Fuxing Zhang, Min Zhuo Molecular Brain 2009, 2 :9 (6 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Effect of the effluent released from the canine internal mammary artery after intraluminal and extraluminal perfusion of acetylcholine and adenosine diphosphate Nilce Mitiko Matsuda, Paul J Pearson, Hartzell V Schaff, Carlos E Piccinato, Alfredo J Rodrigues, Paulo Roberto Barbosa Evora Journal of Biomedical Science 2009, 16 :45 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Correspondence
The "Win-Win" initiative: a global, scientifically based approach to resource sparing treatment for systemic breast cancer therapy Ahmed Elzawawy World Journal of Surgical Oncology 2009, 7 :44 (5 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research article
The frequency of adverse drug reaction related admissions according to method of detection, admission urgency and medical department specialty Miran Brvar, Nina Fokter, Matjaz Bunc, Martin Mozina BMC Clinical Pharmacology 2009, 9 :8 (4 [Abstract ] [Full text ] [PDF ] [PubMed ] [Related articles ]
Research article
Disease modifying and antiangiogenic activity of 2-methoxyestradiol in a murine model of rheumatoid arthritis Stacy M Plum, Eun J Park, Steven J Strawn, Elizabeth G Moore, Carolyn F Sidor, William E Fogler BMC Musculoskeletal Disorders 2009, 10 :46 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
Research
Sympathetic-correlated c-Fos expression in the neonatal rat spinal cord in vitro Chun-Kuei Su, Chiu-Ming Ho, Hsiao-Hui Kuo, Yu-Chuan Wen, Chok-Yung Chai Journal of Biomedical Science 2009, 16 :44 (1 [Abstract ] [Provisional PDF ] [PubMed ] [Related articles ]
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7 acetylcholine receptors underlying allosteric modulation by divalent cations
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