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Qual Saf Health Care. 2006 April; 15(2): 89–91.
doi: 10.1136/qshc.2005.014381.
PMCID: PMC2464821
Use of a standardized protocol to decrease medication errors and adverse events related to sliding scale insulin
A C Donihi, M M DiNardo, M A DeVita, and M T Korytkowski
A C Donihi, M M DiNardo, M A DeVita, M T Korytkowski, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Correspondence to: A C Donihi
Department of Pharmacy and Therapeutics, University of Pittsburgh, 302 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA 15213, USA; calabresea@upmc.edu
Accepted January 6, 2006.
Abstract
Problem
Sliding scale insulin (SSI) is frequently used for inpatient management of hyperglycemia and is associated with a large number of medication errors and adverse events including hypoglycemia and hyperglycemia.
Design
Observational before and after study evaluating the impact of implementation of a standardized SSI protocol and preprinted physician order form.
Setting
University Hospital in Pittsburgh, PA, USA.
Strategy for change
Guidelines for the use of SSI were created by an interdisciplinary committee and implemented in non‐intensive care units. In addition, a preprinted physician order sheet was developed which included the guidelines and an option for ordering one of three standardized insulin sliding scales or a patient specific scale.
Effect of change
One year after implementation the physician order form was used for 91% of orders and, overall, 86% of SSI orders followed the guidelines. The number of prescribing errors found on chart review was reduced from 10.3 per 100 SSI patient‐days at baseline to 1.2 at 1 year (p = 0.03). The number of hyperglycemia episodes 1 year after implementation decreased from 55.9 to 16.3 per 100 SSI patient‐days.
Lessons learnt
The protocol was readily accepted by hospital staff and was associated with decreased prescribing errors and decreased frequency of hyperglycemia.
Keywords: insulin, medication errors, hyperglycemia, practice guidelines