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BMC Genomics

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Editor-in-Chief
Melissa Norton, MD

Biology Editor
Penelope Webb, PhD

In-house Editor
Matthew Kaiser


Welcome to BMC Genomics published by BioMed Central
BMC Genomics is an open access journal publishing original peer-reviewed research articles in all aspects of genome-scale analysis, functional genomics, and proteomics. BMC Genomics (ISSN 1471-2164) is indexed/tracked/covered by PubMed, MEDLINE, BIOSIS, CAS, Scopus, EMBASE, Zoological Record, Thomson Reuters (ISI) and Google Scholar.



BMC  Featured articles   

Meyer et al
BMC Genomics 2009, 10:219
Rapid sequencing of the transcribed genes of coral larvae is made possible by the use of adapted next-generation sequencing methods, revealing around 11,000 expressed genes and candidate genes for the response to temperature stress.
Copyright: BBSRC
BMC Genomics 2009, 10:189
Genes arranged head-to-head and sharing a common bi-directional promoter region display a conserved intergenic architecture in cows, humans and other mammals, which will help to identify regulatory regions and unrecognized genes in other mammals genomes.
Credit: Jupiter Images
BMC Genomics 2009, 10:180
The assembly of the bovine genome used both bacterial artificial chromosome (BAC) and whole genome shotgun (WGS) sequences, exploiting the strengths of each to provide a more accurate and comprehensive coverage of the genome.
Adapted from Yao Fei Hu et al BMC Genomics
BMC Genomics 2009, 10:151
The norepinephrine transporter (NET) is a cocaine and antidepressant target and knockout mice show altered expression of genes in signaling pathways related to neural crest formation and noradrenergic cell differentiation during embryonic development.
Image credit: Jo et al.
BMC Genomics 2009, 10:130
In a yeast model of growth under iron-limited conditions, the role of genes for intracellular trafficking and the peroxisome is determined by combining deletion mutants and expression profiling, which reveal separate metabolic pathway components.


BMC  Related content published in BMC Proceedings


Raleigh, NC, USA. 25-26 October 2007
BMC Proceedings 2008, 3(Suppl 2)
[Content]

BMC Proceedings 2009, 3(Suppl 1)
[Content]


BMC  Latest articles published in BMC Genomics        [more info]


Research article
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays
Joshua S Bloom, Zia Khan, Leonid Kruglyak, Mona Singh, Amy A Caudy
BMC Genomics 2009, 10:221 (12May2009)
[Abstract] [Provisional PDF]

Research article
A network-based integrative approach to prioritize reliable hits from multiple genome-wide RNAi screens in Drosophila
Li Wang, Zhidong Tu, Fengzhu Sun
BMC Genomics 2009, 10:220 (12May2009)
[Abstract] [Provisional PDF]

Research article
Sequencing and de novo analysis of a coral larval transcriptome using 454 GS-Flx
Eli Meyer, Galina V Aglyamova, Shi Wang, Jade Buchanan-Carter, David Abrego, John K Colbourne, Bette L Willis, Mikhail V Matz
BMC Genomics 2009, 10:219 (12May2009)
[Abstract] [Provisional PDF]

Research article
Correlation of expression profiles between microRNAs and mRNA targets using NCI-60 data
Yu-Ping Wang, Kuo-Bin Li
BMC Genomics 2009, 10:218 (12May2009)
[Abstract] [Provisional PDF]

Research article
Ixodes scapularis tick serine proteinase inhibitor (serpin) gene family; annotation and transcriptional analyses
Albert Mulenga, Rabuesak Khumthong, Katelyn C. Chalaire
BMC Genomics 2009, 10:217 (12May2009)
[Abstract] [Provisional PDF]

Research article
Comparative genomics of Toll-like receptor signalling in five species
Oliver C Jann, Annemarie King, Nestor Lopez Corrales, Susan I Anderson, Kirsty Jensen, Tahar Ait-ali, Haizhou Tang, Chunhua Wu, Noelle E Cockett, Alan L Archibald, Elizabeth J Glass
BMC Genomics 2009, 10:216 (11May2009)
[Abstract] [Provisional PDF]

Research article
Dynamic changes in transcripts during regeneration of the secondary vascular system in Populus tomentosa Carr. revealed by cDNA microarrays
Minjie Wang, Xiaoli Qi, Shutang Zhao, Shougong Zhang, Meng-Zhu Lu
BMC Genomics 2009, 10:215 (11May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Identification and target prediction of miRNAs specifically expressed in rat neural tissue
You-Jia Hua, Zhong-Yi Tang, Kang Tu, Li Zhu, Yi-Xue Li, Lu Xie, Hua-Sheng Xiao
BMC Genomics 2009, 10:214 (9May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article
Identification of genes expressed in the hermaphrodite germ line of C. elegans using SAGE
Xin Wang, Yongjun Zhao, Kim Wong, Peter Ehlers, Yuji Kohara, Steven J Jones, Marco A Mara, Robert A Holt, Donald G Moerman, Dave Hansen
BMC Genomics 2009, 10:213 (9May2009)
[Abstract] [Provisional PDF]

Research article
Water deficit alters differentially metabolic pathways affecting important flavor and quality traits in grape berries of Cabernet Sauvignon and Chardonnay
Laurent G Deluc, David R Quilici, Alain Decendit, Jerome Grimplet, Matthew D Wheatley, Karen A Schlauch, Jean-Michel Merillon, John C Cushman, Grant R Cramer
BMC Genomics 2009, 10:212 (8May2009)
[Abstract] [Provisional PDF]


BMC  Latest relevant articles from other journals in BioMed Central


Methodology article
Incorporating functional inter-relationships into protein function prediction algorithms
Gaurav Pandey, Chad L. Myers, Vipin Kumar
BMC Bioinformatics 2009, 10:142 (12May2009)
[Abstract] [Provisional PDF]

Research article
Cold- and light-induced changes in the transcriptome of wheat leading to phase transition from vegetative to reproductive growth
Mark O Winfield, Chungui Lu, Ian D Wilson, Jane A Coghill, Keith J Edwards
BMC Plant Biology 2009, 9:55 (11May2009)
[Abstract] [Provisional PDF]

Analytic perspective
Can we apply the Mendelian randomization methodology without considering epigenetic effects?
Ikechukwu U Ogbuanu, Hongmei Zhang, Wilfried Karmaus
Emerging Themes in Epidemiology 2009, 6:3 (11May2009)
[Abstract] [Provisional PDF]

Research article
Data integration from two microarray platforms identifies bi-allelic genetic inactivation of RIC8A in a breast cancer cell line
Aslaug Aamodt Muggerud, Henrik Edgren, Maija Wolf, Kristine Kleivi, Emelyne Dejeux, Jorg Tost, Therese Sorlie, Olli Kallioniemi
BMC Medical Genomics 2009, 2:26 (11May2009)
[Abstract] [Provisional PDF]

Research article
Similar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas suggest a common pathway to tumorigenesis
Erik F Hensen, Jelle J Goeman, Jan Oosting, Andel GL van der Mey, Pancras CW Hogendoorn, Cor WRJ Cremers, Peter Devilee, Cees J Cornelisse
BMC Medical Genomics 2009, 2:25 (11May2009)
[Abstract] [Provisional PDF]

Database
eCOMPAGT - efficient Combination and Management of Phenotypes and Genotypes for Genetic Epidemiology
Sebastian Schoenherr, Hansi Weissensteiner, Stefan Coassin, Guenther Specht, Florian Kronenberg, Anita Brandstaetter
BMC Bioinformatics 2009, 10:139 (11May2009)
[Abstract] [Provisional PDF]

Research
Insights into the regulation of intrinsically disordered proteins in the human proteome by analysing sequence and gene expression data
Yvonne JK Edwards, Anna Lobley, Melissa M Pentony, David T Jones
Genome Biology 2009, 10:R50 (11May2009)
[Abstract] [Provisional PDF]

Research article
Identification, characterization and utilization of unigene derived microsatellite markers in tea (Camellia sinensis, L)
Ram Kumar Sharma, Pankaj Bhardwaj, Renu Negi, Trilochan Mohapatra, Paramvir Singh Ahuja
BMC Plant Biology 2009, 9:53 (11May2009)
[Abstract] [Provisional PDF]

Commentary
Studying chromosome-wide transcriptional networks: new insights into disease?
Philipp Kapranov
Genome Med 2009, 1:50 (11May2009)
[Abstract] [Full text] [PDF]

Research article
Insights into the evolution of the snail superfamily from metazoan wide molecular phylogenies and expression data in annelids
Pierre Kerner, Johanne Hung, Julien Behague, Martine Le Gouar, Guillaume Balavoine, Michel Vervoort
BMC Evolutionary Biology 2009, 9:94 (9May2009)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

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