| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 1–2. doi: 10.1073/iti0106103.PMCID: PMC1324970 Commentaries More barrels from the viral tree of life Roger M. Burnett Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 3–4. Published online 2005 December 27. doi: 10.1073/pnas.0509852102.PMCID: PMC1325008 Mesozoic aviary takes form Alan Feduccia Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 5–6. Published online 2005 December 27. doi: 10.1073/pnas.0509970102.PMCID: PMC1325012 Profile Profile of Xiaodong Wang Nick Zagorski Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 7–9. Published online 2005 December 27. doi: 10.1073/pnas.0509187103.PMCID: PMC1324996 Physical Sciences Chemistry Complementary base-pair-facilitated electron tunneling for electrically pinpointing complementary nucleobases Takahito Ohshiro and Yoshio Umezawa Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 10–14. Published online 2005 December 22. doi: 10.1073/pnas.0506130103.PMCID: PMC1324978 Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen Cheng-Yuan Huang, Desiree A. Thayer, Aileen Y. Chang, Michael D. Best, Julia Hoffmann, Steve Head, and Chi-Huey Wong Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 15–20. Published online 2005 December 22. doi: 10.1073/pnas.0509693102.PMCID: PMC1325001 Computer Sciences Mapping of orthologous genes in the context of biological pathways: An application of integer programming Fenglou Mao, Zhengchang Su, Victor Olman, Phuongan Dam, Zhijie Liu, and Ying Xu Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 129–134. Published online 2005 December 22. doi: 10.1073/pnas.0509737102.PMCID: PMC1325003 Global landscape of recent inferred Darwinian selection for Homo sapiens Eric T. Wang, Greg Kodama, Pierre Baldi, and Robert K. Moyzis Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 135–140. Published online 2005 December 21. doi: 10.1073/pnas.0509691102.PMCID: PMC1317879 Biological Sciences Biochemistry From the Cover: Protein fucosylation regulates synapsin Ia/Ib expression and neuronal morphology in primary hippocampal neurons Heather E. Murrey, Cristal I. Gama, Stacey A. Kalovidouris, Wen.-I. Luo, Edward M. Driggers, Barbara Porton, and Linda C. Hsieh-Wilson Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 21–26. Published online 2005 December 22. doi: 10.1073/pnas.0503381102.PMCID: PMC1324972 From the Cover: Crystal structure of phycocyanobilin:ferredoxin oxidoreductase in complex with biliverdin IXα, a key enzyme in the biosynthesis of phycocyanobilin Yoshinori Hagiwara, Masakazu Sugishima, Yasuhiro Takahashi, and Keiichi Fukuyama Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 27–32. Published online 2005 December 27. doi: 10.1073/pnas.0507266103.PMCID: PMC1324987 Evidence for the direct involvement of βTrCP in Gli3 protein processing Baolin Wang and Yanyun Li Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 33–38. Published online 2005 December 21. doi: 10.1073/pnas.0509927103.PMCID: PMC1325010 Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic Letizia Brandi, Attilio Fabbretti, Anna La Teana, Monica Abbondi, Daniele Losi, Stefano Donadio, and Claudio O. Gualerzi Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 39–44. Published online 2005 December 27. doi: 10.1073/pnas.0507740102.PMCID: PMC1324990 PDSM, a motif for phosphorylation-dependent SUMO modification Ville Hietakangas, Julius Anckar, Henri A. Blomster, Mitsuaki Fujimoto, Jorma J. Palvimo, Akira Nakai, and Lea Sistonen Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 45–50. Published online 2005 December 21. doi: 10.1073/pnas.0503698102.PMCID: PMC1324973 Molecular cloning, expression, and structural prediction of deoxyhypusine hydroxylase: A HEAT-repeat-containing metalloenzyme Jong-Hwan Park, L. Aravind, Edith C. Wolff, Jörn Kaevel, Yeon Sook Kim, and Myung Hee Park Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 51–56. Published online 2005 December 21. doi: 10.1073/pnas.0509348102.PMCID: PMC1324997 V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors O. M. Grbovic, A. D. Basso, A. Sawai, Q. Ye, P. Friedlander, D. Solit, and N. Rosen Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 57–62. Published online 2005 December 21. doi: 10.1073/pnas.0609973103.PMCID: PMC1325013 Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2α RNA-dependent protein kinase Qiaozhu Su, Shuo Wang, Dionissios Baltzis, Li-Ke Qu, Andrew Hoi-Tao Wong, and Antonis E. Koromilas Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 63–68. Published online 2005 December 22. doi: 10.1073/pnas.0508207103.PMCID: PMC1324992 Intraprotein transfer of the quinone analogue inhibitor 2,5-dibromo-3-methyl-6-isopropyl-p-benzoquinone in the cytochrome b6f complex Jiusheng Yan, Genji Kurisu, and William A. Cramer Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 69–74. Published online 2005 December 21. doi: 10.1073/pnas.0504909102.PMCID: PMC1324977 CYP27B1 null mice with LacZreporter gene display no 25-hydroxyvitamin D3-1α-hydroxylase promoter activity in the skin Janeen L. Vanhooke, Jean M. Prahl, Christine Kimmel-Jehan, Monica Mendelsohn, Eric W. Danielson, Kevin D. Healy, and Hector F. DeLuca Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 75–80. Published online 2005 December 21. doi: 10.1073/pnas.0509734103.PMCID: PMC1325002 A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme Dirk Roeser, Andrea Preusser-Kunze, Bernhard Schmidt, Kathrin Gasow, Julia G. Wittmann, Thomas Dierks, Kurt von Figura, and Markus Georg Rudolph Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 81–86. Published online 2005 December 20. doi: 10.1073/pnas.0507592102.PMCID: PMC1324989 Biophysics Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actin M. Capitanio, M. Canepari, P. Cacciafesta, V. Lombardi, R. Cicchi, M. Maffei, F. S. Pavone, and R. Bottinelli Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 87–92. Published online 2005 December 21. doi: 10.1073/pnas.0506830102.PMCID: PMC1324983 Multiple stepwise refolding of immunoglobulin domain I27 upon force quench depends on initial conditions Mai Suan Li, Chin-Kun Hu, Dmitri K. Klimov, and D. Thirumalai Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 93–98. Published online 2005 December 22. doi: 10.1073/pnas.0503758103.PMCID: PMC1324974 Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7 Joerg Gsponer, Harri Hopearuoho, Sara B.-M. Whittaker, Graham R. Spence, Geoffrey R. Moore, Emanuele Paci, Sheena E. Radford, and Michele Vendruscolo Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 99–104. Published online 2005 December 21. doi: 10.1073/pnas.0508667102.PMCID: PMC1324994 Cell Biology From the Cover: Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production Michal Safran, William Y. Kim, Fionnuala O'Connell, Lee Flippin, Volkmar Günzler, James W. Horner, Ronald A. DePinho, and William G. Kaelin, Jr. Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 105–110. Published online 2005 December 22. doi: 10.1073/pnas.0509459103.PMCID: PMC1324998 PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry Matthias Groszer, Rebecca Erickson, Deirdre D. Scripture-Adams, Joseph D. Dougherty, Janel Le Belle, Jerome A. Zack, Daniel H. Geschwind, Xin Liu, Harley I. Kornblum, and Hong Wu Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 111–116. Published online 2005 December 22. doi: 10.1073/pnas.0509939103.PMCID: PMC1325011 Environmental Sciences Predicting microbial species richness Sun-Hee Hong, John Bunge, Sun-Ok Jeon, and Slava S. Epstein Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 117–122. Published online 2005 December 20. doi: 10.1073/pnas.0507245102.PMCID: PMC1324986 Genetics Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor–/– mice Daniel Teupser, Marietta Tan, Adam D. Persky, and Jan L. Breslow Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 123–128. Published online 2005 December 27. doi: 10.1073/pnas.0509570102.PMCID: PMC1324999 Mapping of orthologous genes in the context of biological pathways: An application of integer programming Fenglou Mao, Zhengchang Su, Victor Olman, Phuongan Dam, Zhijie Liu, and Ying Xu Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 129–134. Published online 2005 December 22. doi: 10.1073/pnas.0509737102.PMCID: PMC1325003 Global landscape of recent inferred Darwinian selection for Homo sapiens Eric T. Wang, Greg Kodama, Pierre Baldi, and Robert K. Moyzis Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 135–140. Published online 2005 December 21. doi: 10.1073/pnas.0509691102.PMCID: PMC1317879 Immunology Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen Cheng-Yuan Huang, Desiree A. Thayer, Aileen Y. Chang, Michael D. Best, Julia Hoffmann, Steve Head, and Chi-Huey Wong Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 15–20. Published online 2005 December 22. doi: 10.1073/pnas.0509693102.PMCID: PMC1325001 Internalization and phagosome escape required for Francisella to induce human monocyte IL-1β processing and release Mikhail A. Gavrilin, Imad J. Bouakl, Nina L. Knatz, Michelle D. Duncan, Mark W. Hall, John S. Gunn, and Mark D. Wewers Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 141–146. Published online 2005 December 22. doi: 10.1073/pnas.0504271103.PMCID: PMC1324976 Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8+ T cells in vivo Jianping Yang, Stephanie P. Huck, Rebecca S. McHugh, Ian F. Hermans, and Franca Ronchese Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 147–152. Published online 2005 December 22. doi: 10.1073/pnas.0509054103.PMCID: PMC1324995 Regulation of dendritic cell maturation and function by Bruton's tyrosine kinase via IL-10 and Stat3 Yuko Kawakami, Naoki Inagaki, Shahram Salek-Ardakani, Jiro Kitaura, Hiroyuki Tanaka, Koichi Nagao, Yu Kawakami, Wenbin Xiao, Hiroichi Nagai, Michael Croft, and Toshiaki Kawakami Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 153–158. Published online 2005 December 21. doi: 10.1073/pnas.0509784103.PMCID: PMC1325006 Medical Sciences Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents Ilia Fishbein, Ivan S. Alferiev, Origene Nyanguile, Richard Gaster, John M. Vohs, Gordon S. Wong, Howard Felderman, I-Wei Chen, Hoon Choi, Robert L. Wilensky, and Robert J. Levy Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 159–164. Published online 2005 December 21. doi: 10.1073/pnas.0502945102.PMCID: PMC1317877 Microbiology The Bacillus subtilis spore coat provides “eat resistance” during phagocytic predation by the protozoan Tetrahymena thermophila Lawrence A. Klobutcher, Katerina Ragkousi, and Peter Setlow Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 165–170. Published online 2005 December 21. doi: 10.1073/pnas.0507121102.PMCID: PMC1324984 Multiple sensors control reciprocal expression of Pseudomonas aeruginosa regulatory RNA and virulence genes Isabelle Ventre, Andrew L. Goodman, Isabelle Vallet-Gely, Perrine Vasseur, Chantal Soscia, Søren Molin, Sophie Bleves, Andrée Lazdunski, Stephen Lory, and Alain Filloux Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 171–176. Published online 2005 December 22. doi: 10.1073/pnas.0507407103.PMCID: PMC1324988 Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria Frank P. Mockenhaupt, Jakob P. Cramer, Lutz Hamann, Miriam S. Stegemann, Jana Eckert, Na-Ri Oh, Rowland N. Otchwemah, Ekkehart Dietz, Stephan Ehrhardt, Nicolas W. J. Schröder, Ulrich Bienzle, and Ralf R. Schumann Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 177–182. Published online 2005 December 21. doi: 10.1073/pnas.0506803102.PMCID: PMC1324982 Neuroscience Silent plateau potentials, rhythmic bursts, and pacemaker firing: Three patterns of activity that coexist in quadristable subthalamic neurons Jason I. Kass and Isabelle M. Mintz Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 183–188. Published online 2005 December 22. doi: 10.1073/pnas.0506781102.PMCID: PMC1324981 Neural activity in speech-sensitive auditory cortex during silence M. D. Hunter, S. B. Eickhoff, T. W. R. Miller, T. F. D. Farrow, I. D. Wilkinson, and P. W. R. Woodruff Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 189–194. Published online 2005 December 21. doi: 10.1073/pnas.0506268103.PMCID: PMC1317878 Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity Stefan Berger, David P. Wolfer, Oliver Selbach, Heike Alter, Gitta Erdmann, Holger M. Reichardt, Aisa N. Chepkova, Hans Welzl, Helmut L. Haas, Hans-Peter Lipp, and Günther Schütz Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 195–200. Published online 2005 December 20. doi: 10.1073/pnas.0503878102.PMCID: PMC1324975 From the Cover: Inhibitory control by an integral feedback signal in prefrontal cortex: A model of discrimination between sequential stimuli Paul Miller and Xiao-Jing Wang Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 201–206. Published online 2005 December 21. doi: 10.1073/pnas.0508072103.PMCID: PMC1324991 Stimulation of muscarinic receptors mimics experience-dependent plasticity in the honey bee brain Nyla Ismail, Gene E. Robinson, and Susan E. Fahrbach Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 207–211. Published online 2005 December 22. doi: 10.1073/pnas.0508318102.PMCID: PMC1324993 Pharmacology Giα and Gβ subunits both define selectivity of G protein activation by α2-adrenergic receptors Scott K. Gibson and Alfred G. Gilman Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 212–217. Published online 2005 December 21. doi: 10.1073/pnas.0509763102.PMCID: PMC1325004 Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide N. R. F. Nascimento, L. M. A. Lessa, M. R. Kerntopf, C. M. Sousa, R. S. Alves, M. G. R. Queiroz, J. Price, D. B. Heimark, J. Larner, X. Du, M. Brownlee, A. Gow, C. Davis, and M. C. Fonteles Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 218–223. Published online 2005 December 22. doi: 10.1073/pnas.0509779103.PMCID: PMC1325005 Physiology From the Cover: Premature ovarian failure in androgen receptor-deficient mice Hiroko Shiina, Takahiro Matsumoto, Takashi Sato, Katsuhide Igarashi, Junko Miyamoto, Sayuri Takemasa, Matomo Sakari, Ichiro Takada, Takashi Nakamura, Daniel Metzger, Pierre Chambon, Jun Kanno, Hiroyuki Yoshikawa, and Shigeaki Kato Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 224–229. Published online 2005 December 22. doi: 10.1073/pnas.0506736102.PMCID: PMC1324980 Plant Biology Cinnamoyl-CoA reductase, a key enzyme in lignin biosynthesis, is an effector of small GTPase Rac in defense signaling in rice Tsutomu Kawasaki, Hisako Koita, Tomoyuki Nakatsubo, Kana Hasegawa, Kenichi Wakabayashi, Hiroki Takahashi, Kenji Umemura, Toshiaki Umezawa, and Ko Shimamoto Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 230–235. Published online 2005 December 27. doi: 10.1073/pnas.0509875103.PMCID: PMC1325009 A gradient of auxin and auxin-dependent transcription precedes tropic growth responses C. Alex Esmon, Amanda G. Tinsley, Karin Ljung, Goran Sandberg, Leonard B. Hearne, and Emmanuel Liscum Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 236–241. Published online 2005 December 21. doi: 10.1073/pnas.0507127103.PMCID: PMC1324985 Social Sciences Anthropology The questionable contribution of the Neolithic and the Bronze Age to European craniofacial form C. Loring Brace, Noriko Seguchi, Conrad B. Quintyn, Sherry C. Fox, A. Russell Nelson, Sotiris K. Manolis, and Pan Qifeng Proc Natl Acad Sci U S A. 2006 January 3; 103(1): 242–247. Published online 2005 December 21. doi: 10.1073/pnas.0509801102.PMCID: PMC1325007 |