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Volume 94(7);  April 1, 1997
From the Academy
Introduction to Frontiers of Science
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2773.
PMCID: PMC34143
Bose–Einstein condensation
John Doyle
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2774–2775.
PMCID: PMC34144
The cell cycle and cancer
Kathleen Collins, Tyler Jacks, and Nikola P. Pavletich
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2776–2778.
PMCID: PMC34145
Combinatorial thinking in chemistry and biology
Jonathan Ellman, Barry Stoddard, and Jim Wells
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2779–2782.
PMCID: PMC34146
The epoch of galaxy formation
David N. Spergel, Simon J. Lilly, and Charles Steidel
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2783–2784.
PMCID: PMC34147
Genetic analyses of complex behavioral disorders
George R. Uhl, Lisa H. Gold, and Neil Risch
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2785–2786.
PMCID: PMC34148
Imaging the living human brain: Magnetic resonance imaging and positron emission tomography
Nora D. Volkow, Bruce Rosen, and Lars Farde
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2787–2788.
PMCID: PMC34149
Security and privacy in the information economy
Joan Feigenbaum, Steven Rudich, Matt Blaze, and Kevin McCurley
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2789–2792.
PMCID: PMC34150
Signaling in plants
R. Michael Mulligan, Joanne Chory, and Joseph R. Ecker
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2793–2795.
PMCID: PMC34151
Commentaries
Helix is a helix is a helix?
Lynne Regan
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2796–2797.
PMCID: PMC34152
Phospholipase Cγ activation and phosphoinositide hydrolysis are essential for embryonal development
Joseph Schlessinger
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2798–2799.
PMCID: PMC34153
Evolutionary developmental biology meets the brain: The origins of mammalian cortex
Harvey J. Karten
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2800–2804.
PMCID: PMC34154
Physical Sciences
Chemistry
Encoded combinatorial chemistry: Synthesis and screening of a library of highly functionalized pyrrolidines
Derek Maclean, John R. Schullek, Martin M. Murphy, Zhi-Jie Ni, Eric M. Gordon, and Mark A. Gallop
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2805–2810.
PMCID: PMC20277
Biological Sciences
Biochemistry
Supercoiling-dependent flexibility of adenosine-tract-containing DNA detected by a topological method
Hua Tsen and Stephen D. Levene
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2817–2822.
PMCID: PMC20279
A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains
Anamitra Bhattacharyya and Elizabeth H. Blackburn
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2823–2827.
PMCID: PMC20280
Phosphorylation stimulates the cooperative DNA-binding properties of the transcription factor OmpR
Ke-Jung Huang, Chung-Yu Lan, and Michele M. Igo
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2828–2832.
PMCID: PMC20281
A direct comparison of helix propensity in proteins and peptides
Jeffrey K. Myers, C. Nick Pace, and J. Martin Scholtz
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2833–2837.
PMCID: PMC20282
Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein, and single-stranded DNA
Sam S.-K. Lee and I. R. Lehman
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2838–2842.
PMCID: PMC20283
The structure of a CAP–DNA complex having two cAMP molecules bound to each monomer
J. M. Passner and T. A. Steitz
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2843–2847.
PMCID: PMC20284
Membrane-promoted unfolding of acetylcholinesterase: A possible mechanism for insertion into the lipid bilayer
Irina Shin, David Kreimer, Israel Silman, and Lev Weiner
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2848–2852.
PMCID: PMC20285
The β subunit of the high-conductance calcium-activated potassium channel contributes to the high-affinity receptor for charybdotoxin
Markus Hanner, William A. Schmalhofer, Petraki Munujos, Hans-Günther Knaus, Gregory J. Kaczorowski, and Maria L. Garcia
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2853–2858.
PMCID: PMC20286
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
Amir Rattner, Jen-Chih Hsieh, Philip M. Smallwood, Debra J. Gilbert, Neil G. Copeland, Nancy A. Jenkins, and Jeremy Nathans
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2859–2863.
PMCID: PMC20287
Synthesis of functional eukaryotic ribosomal RNAs in trans: Development of a novel in vivo rDNA system for dissecting ribosome biogenesis
Wen-Qing Liang and Maurille J. Fournier
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2864–2868.
PMCID: PMC20288
Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation
Paul Schwenger, Paola Bellosta, Ilja Vietor, Claudio Basilico, Edward Y. Skolnik, and Jan Vilček
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2869–2873.
PMCID: PMC20289
Crystal structure of varicella-zoster virus protease
Xiayang Qiu, Cheryl A. Janson, Jeffrey S. Culp, Susan B. Richardson, Christine Debouck, Ward W. Smith, and Sherin S. Abdel-Meguid
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2874–2879.
PMCID: PMC20290
A novel arachidonate-preferring acyl-CoA synthetase is present in steroidogenic cells of the rat adrenal, ovary, and testis
Man-Jong Kang, Takahiro Fujino, Hironobu Sasano, Hiroyuki Minekura, Noritaka Yabuki, Hiroshi Nagura, Hiroaki Iijima, and Tokuo T. Yamamoto
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2880–2884.
PMCID: PMC20291
Nucleosome-mediated synergism between transcription factors on the mouse mammary tumor virus promoter
Sebastián Chávez and Miguel Beato
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2885–2890.
PMCID: PMC20292
Lucigenin luminescence as a measure of intracellular superoxide dismutase activity in Escherichia coli
Stefan I. Liochev and Irwin Fridovich
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2891–2896.
PMCID: PMC20293
Expression cloning and characterization of a cDNA encoding a novel membrane protein required for the formation of O-acetylated ganglioside: A putative acetyl-CoA transporter
Akiko Kanamori, Jun Nakayama, Michiko N. Fukuda, William B. Stallcup, Katsutoshi Sasaki, Minoru Fukuda, and Yoshio Hirabayashi
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2897–2902.
PMCID: PMC20294
Defining the chemical groups essential for Tetrahymena group I intron function by nucleotide analog interference mapping
Scott A. Strobel and Kanaka Shetty
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2903–2908.
PMCID: PMC20295
Minus-strand origin of filamentous phage versus transcriptional promoters in recognition of RNA polymerase
Atsushi Higashitani, Nahoko Higashitani, and Kensuke Horiuchi
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2909–2914.
PMCID: PMC20296
Characterization of soluble forms of nonchimeric type V adenylyl cyclases
Klaus Scholich, Ann J. Barbier, Jason B. Mullenix, and Tarun B. Patel
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2915–2920.
PMCID: PMC20297
In vitro evolution of terminal protein-containing genomes
José A. Esteban, Luis Blanco, Laurentino Villar, and Margarita Salas
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2921–2926.
PMCID: PMC20298
CREB-binding protein/p300 are transcriptional coactivators of p65
Mary E. Gerritsen, Amy J. Williams, Andrew S. Neish, Sarah Moore, Yang Shi, and Tucker Collins
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2927–2932.
PMCID: PMC20299
Introduction of an RRHR motif into chicken urokinase-type plasminogen activator (ch-uPA) confers sensitivity to plasminogen activator inhibitor (PAI)-1 and PAI-2 and allows ch-uPA-mediated extracellular matrix degradation to be controlled by PAI-1
John D. Sipley, Daniela S. Alexander, Jacqueline E. Testa, and James P. Quigley
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2933–2938.
PMCID: PMC20300
Subunit arrangement in the human 20S proteasome
Friedrich Kopp, Klavs B. Hendil, Burkhardt Dahlmann, Poul Kristensen, Axel Sobek, and Wolfgang Uerkvitz
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2939–2944.
PMCID: PMC20301
The core domain of a new retina specific RGS protein stimulates the GTPase activity of transducin in vitro
Eva Faurobert and James B. Hurley
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2945–2950.
PMCID: PMC20302
Single-strand DNA intermediates in phage λ’s Red recombination pathway
Stuart A. Hill, Mary M. Stahl, and Franklin W. Stahl
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2951–2956.
PMCID: PMC20303
Interaction of Gal repressor with inducer and operator: Induction of gal transcription from repressor-bound DNA
Sumana Chatterjee, Yan-Ning Zhou, Siddhartha Roy, and Sankar Adhya
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2957–2962.
PMCID: PMC20304
Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase
Sandrine Cadel, Thierry Foulon, Annie Viron, Agnès Balogh, Stéphanie Midol-Monnet, Nadine Noël, and Paul Cohen
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2963–2968.
PMCID: PMC20305
Modification of protein surface hydrophobicity and methionine oxidation by oxidative systems
Chien-Chung Chao, Yan-Shan Ma, and Earl R. Stadtman
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2969–2974.
PMCID: PMC20306
Crystal structure of desheptapeptide(B24–B30)insulin at 1.6 Å resolution: Implications for receptor binding
Su-jin Bao, Dian-lin Xie, Ji-ping Zhang, Wen-rui Chang, and Dong-cai Liang
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2975–2980.
PMCID: PMC20307
Mössbauer studies of alkane ω-hydroxylase: Evidence for a diiron cluster in an integral-membrane enzyme
John Shanklin, Catalina Achim, Hermann Schmidt, Brian G. Fox, and Eckard Münck
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2981–2986.
PMCID: PMC20308
Gene 4 helicase of bacteriophage T7 mediates strand transfer through pyrimidine dimers, mismatches, and nonhomologous regions
Daochun Kong, Jack D. Griffith, and Charles C. Richardson
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2987–2992.
PMCID: PMC20309
Biophysics
Local DNA stretching mimics the distortion caused by the TATA box-binding protein
Anne Lebrun, Zippora Shakked, and Richard Lavery
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2993–2998.
PMCID: PMC20310
Cell Biology
Essential role of the tyrosine kinase substrate phospholipase C-γ1 in mammalian growth and development
Qun-sheng Ji, Glenn E. Winnier, Kevin D. Niswender, Debra Horstman, Ron Wisdom, Mark A. Magnuson, and Graham Carpenter
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2999–3003.
PMCID: PMC20311
Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity
Di Yang, Cathy Tournier, Mark Wysk, Hong-Tao Lu, Jie Xu, Roger J. Davis, and Richard A. Flavell
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3004–3009.
PMCID: PMC20312
cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein
C. H. Chris Yun, Soohyuk Oh, Mirza Zizak, Deborah Steplock, Su Tsao, Chung-Ming Tse, Edward J. Weinman, and Mark Donowitz
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3010–3015.
PMCID: PMC20313
Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors
Ursula Klingmüller, Hong Wu, Jonathan G. Hsiao, Alex Toker, Brian C. Duckworth, Lewis C. Cantley, and Harvey F. Lodish
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3016–3021.
PMCID: PMC20314
Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold
Shirwin M. Pockwinse, Gabriela Krockmalnic, Stephen J. Doxsey, Jeffrey Nickerson, Jane B. Lian, André J. van Wijnen, Janet L. Stein, Gary S. Stein, and Sheldon Penman
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3022–3027.
PMCID: PMC20315
Ras-independent transformation by v-Src
Dana T. Aftab, Joanne Kwan, and G. Steven Martin
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3028–3033.
PMCID: PMC20316
Nuclear and cytoplasmic localizations of the adenomatous polyposis coli protein
Kristi L. Neufeld and Raymond L. White
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3034–3039.
PMCID: PMC20317
The ultrastructural localization of 60-kDa Ro protein and human cytoplasmic RNAs: Association with novel electron-dense bodies
A. Darise Farris, Francine Puvion-Dutilleul, Edmond Puvion, John B. Harley, and Lela A. Lee
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3040–3045.
PMCID: PMC20318
A conserved domain is present in different families of vesicular fusion proteins: A new superfamily
Thomas Weimbs, Seng Hui Low, Steven J. Chapin, Keith E. Mostov, Philipp Bucher, and Kay Hofmann
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3046–3051.
PMCID: PMC20319
Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases
Cindy Knall, G. Scott Worthen, and Gary L. Johnson
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3052–3057.
PMCID: PMC20320
Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice
Thorsten M. Schlaeger, Sona Bartunkova, Joel A. Lawitts, Gunnar Teichmann, Werner Risau, Urban Deutsch, and Thomas N. Sato
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3058–3063.
PMCID: PMC20321
Mitochondrial decay in hepatocytes from old rats: Membrane potential declines, heterogeneity and oxidants increase
Tory M. Hagen, David L. Yowe, James C. Bartholomew, Carol M. Wehr, Katherine L. Do, Jin-Y. Park, and Bruce N. Ames
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3064–3069.
PMCID: PMC20322
Target of rapamycin proteins and their kinase activities are required for meiosis
Xiao-Feng Zheng and Stuart L. Schreiber
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3070–3075.
PMCID: PMC20323
A proliferation switch for genetically modified cells
C. Anthony Blau, Kenneth R. Peterson, Jonathan G. Drachman, and David M. Spencer
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3076–3081.
PMCID: PMC20324
Developmental Biology
Jak1 kinase is required for cell migrations and anterior specification in zebrafish embryos
Greg Conway, Ayelet Margoliath, Sharon Wong-Madden, Richard J. Roberts, and Walter Gilbert
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3082–3087.
PMCID: PMC20325
rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina
Takahisa Furukawa, Christine A. Kozak, and Constance L. Cepko
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3088–3093.
PMCID: PMC20326
The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryo
Lorena Lim, Heping Zhou, and Robert H. Costa
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3094–3099.
PMCID: PMC20327
Evolution
Protein engineering reveals ancient adaptive replacements in isocitrate dehydrogenase
Antony M. Dean and G. Brian Golding
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3104–3109.
PMCID: PMC20329
Genetics
TCOF1 gene encodes a putative nucleolar phosphoprotein that exhibits mutations in Treacher Collins Syndrome throughout its coding region
Carol A. Wise, Lydia C. Chiang, William A. Paznekas, Mridula Sharma, Maurice M. Musy, Jennifer A. Ashley, Michael Lovett, and Ethylin W. Jabs
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3110–3115.
PMCID: PMC20330
A common mutational pattern in Cockayne syndrome patients from xeroderma pigmentosum group G: Implications for a second XPG function
Thierry Nouspikel, Philippe Lalle, Steven A. Leadon, Priscilla K. Cooper, and Stuart G. Clarkson
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3116–3121.
PMCID: PMC20331
Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2
Latha Narayanan, James A. Fritzell, Sean M. Baker, R. Michael Liskay, and Peter M. Glazer
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3122–3127.
PMCID: PMC20332
Molecular characterization of TUB, TULP1, and TULP2, members of the novel tubby gene family and their possible relation to ocular diseases
Michael A. North, Juergen K. Naggert, Yingzhuo Yan, Konrad Noben-Trauth, and Patsy M. Nishina
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3128–3133.
PMCID: PMC20333
Promoter-creating mutations in Pseudomonas putida: A model system for the study of mutation in starving bacteria
Lagle Kasak, Rita Hõrak, and Maia Kivisaar
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3134–3139.
PMCID: PMC20334
Molecular structure of a wheat chromosome end healed after gametocidal gene-induced breakage
H. Tsujimoto, T. Yamada, and T. Sasakuma
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3140–3144.
PMCID: PMC20335
Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2  in vivo
Ellen L. Gadbois, David M. Chao, Joseph C. Reese, Michael R. Green, and Richard A. Young
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3145–3150.
PMCID: PMC20336
mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p
Christopher F. J. Hardy, Olga Dryga, Sara Seematter, Paula M. B. Pahl, and Robert A. Sclafani
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3151–3155.
PMCID: PMC20337
Immunology
Folding of the conserved domain but not of flanking regions in the integrin β2 subunit requires association with the α subunit
Chichi Huang, Chafen Lu, and Timothy A. Springer
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3156–3161.
PMCID: PMC20338
Folding of the β-propeller domain of the integrin αL subunit is independent of the I domain and dependent on the β2 subunit
Chichi Huang and Timothy A. Springer
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3162–3167.
PMCID: PMC20339
Human immune disorder arising from mutation of the α chain of the interleukin-2 receptor
Nigel Sharfe, Harjit K. Dadi, Michal Shahar, and Chaim M. Roifman
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3168–3171.
PMCID: PMC20340
Rolling and transient tethering of leukocytes on antibodies reveal specializations of selectins
Shuqi Chen, Ronen Alon, Robert C. Fuhlbrigge, and Timothy A. Springer
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3172–3177.
PMCID: PMC20341
Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway
Emerita Brigino, Soichi Haraguchi, Angelos Koutsonikolis, George J. Cianciolo, Una Owens, Robert A. Good, and Noorbibi K. Day
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3178–3182.
PMCID: PMC20342
Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine
Vincenzo Bronte, Miles W. Carroll, Theresa J. Goletz, Michael Wang, Willem W. Overwijk, Francesco Marincola, Steven A. Rosenberg, Bernard Moss, and Nicholas P. Restifo
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3183–3188.
PMCID: PMC20343
In differentiated CD4+ T Cells, interleukin 4 production is cytokine-autonomous, whereas interferon γ production is cytokine-dependent
Jane Hu-Li, Hua Huang, John Ryan, and William E. Paul
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3189–3194.
PMCID: PMC20344
Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation
Anthony G. Wilson, Julian A. Symons, Tarra L. McDowell, Hugh O. McDevitt, and Gordon W. Duff
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3195–3199.
PMCID: PMC20345
A peptide composed of tandem analogs of two myasthenogenic T cell epitopes interferes with specific autoimmune responses
Yael Katz-Levy, Miri Paas-Rozner, Susan Kirshner, Molly Dayan, Einat Zisman, Mati Fridkin, Itzhak Wirguin, Michael Sela, and Edna Mozes
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3200–3205.
PMCID: PMC20346
Medical Sciences
Cloning and characterization of the extreme 5′-terminal sequences of the RNA genomes of GB virus C/hepatitis G virus
Sen-Yung Hsieh, Pei-Ying Yang, Hsiao-Chin Chen, and Yun-Fan Liaw
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3206–3210.
PMCID: PMC20347
Inflammation and NOx-induced nitration: Assay for 3-nitrotyrosine by HPLC with electrochemical detection
Mark K. Shigenaga, Ho H. Lee, Benjamin C. Blount, Stephan Christen, Eric T. Shigeno, Helena Yip, and Bruce N. Ames
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3211–3216.
PMCID: PMC20348
γ-Tocopherol traps mutagenic electrophiles such as NOx and complements α-tocopherol: Physiological implications
Stephan Christen, Alan A. Woodall, Mark K. Shigenaga, Peter T. Southwell-Keely, Mark W. Duncan, and Bruce N. Ames
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3217–3222.
PMCID: PMC20349
Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B
Allan Z. Zhao, Hong Zhao, Jeanette Teague, Wilfred Fujimoto, and Joseph A. Beavo
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3223–3228.
PMCID: PMC20350
AIM1, a novel non-lens member of the βγ-crystallin superfamily, is associated with the control of tumorigenicity in human malignant melanoma
Michael E. Ray, Graeme Wistow, Yan A. Su, Paul S. Meltzer, and Jeffrey M. Trent
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3229–3234.
PMCID: PMC20351
Regular alcohol consumption mimics cardiac preconditioning by protecting against ischemia–reperfusion injury
Masami Miyamae, Ivan Diamond, Michael W. Weiner, S. Albert Camacho, and Vincent M. Figueredo
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3235–3239.
PMCID: PMC20352
Ectopic expression of A-myb in transgenic mice causes follicular hyperplasia and enhanced B lymphocyte proliferation
Susan E. DeRocco, Renato Iozzo, XiaoPing Ma, Roland Schwarting, David Peterson, and Bruno Calabretta
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3240–3244.
PMCID: PMC20353
Inhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosis
Takashi Shimamoto, Shuji Nakamura, Jacques Bollekens, Frank H. Ruddle, and Kenichi Takeshita
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3245–3249.
PMCID: PMC20354
Trans receptor inhibition of human glioblastoma cells by erbB family ectodomains
Donald M. O’Rourke, Xiaolan Qian, Hong-Tao Zhang, James G. Davis, Eric Nute, Judith Meinkoth, and Mark I. Greene
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3250–3255.
PMCID: PMC20355
Transloading of tumor antigen-derived peptides into antigen-presenting cells
Michael Buschle, Walter Schmidt, Wolfgang Zauner, Karl Mechtler, Barbara Trska, Helen Kirlappos, and Max L. Birnstiel
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3256–3261.
PMCID: PMC20356
Cell-free tumor antigen peptide-based cancer vaccines
Walter Schmidt, Michael Buschle, Wolfgang Zauner, Helen Kirlappos, Karl Mechtler, Barbara Trska, and Max L. Birnstiel
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3262–3267.
PMCID: PMC20357
Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands
Christine Delporte, Brian C. O’Connell, Xinjun He, Henry E. Lancaster, Anne C. O’Connell, Peter Agre, and Bruce J. Baum
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3268–3273.
PMCID: PMC20358
Prevention of insect-borne disease: An approach using transgenic symbiotic bacteria
Ravi V. Durvasula, Andrew Gumbs, Anil Panackal, Oleg Kruglov, Serap Aksoy, R. Bruce Merrifield, Frank F. Richards, and Charles B. Beard
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3274–3278.
PMCID: PMC20359
A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis
Sandy D. Der, Yi-Li Yang, Charles Weissmann, and Bryan R. G. Williams
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3279–3283.
PMCID: PMC20360
Peptide-induced nasal tolerance for a mycobacterial heat shock protein 60 T cell epitope in rats suppresses both adjuvant arthritis and nonmicrobially induced experimental arthritis
Berent J. Prakken, Ruurd van der Zee, Stephen M. Anderton, Peter J. S. van Kooten, Wietse Kuis, and Willem van Eden
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3284–3289.
PMCID: PMC20361
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: Implications for cancer and neuronal damage
Benjamin C. Blount, Matthew M. Mack, Carol M. Wehr, James T. MacGregor, Robert A. Hiatt, Gene Wang, Sunitha N. Wickramasinghe, Richard B. Everson, and Bruce N. Ames
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3290–3295.
PMCID: PMC20362
Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity
Paolo Salomoni, Danilo Perrotti, Robert Martinez, Claudio Franceschi, and Bruno Calabretta
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3296–3301.
PMCID: PMC20363
Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway
Evelyne Goillot, Joel Raingeaud, Ann Ranger, Robert I. Tepper, Roger. J. Davis, Ed Harlow, and Irma Sanchez
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3302–3307.
PMCID: PMC20364
Dietary fat influences on polyp phenotype in multiple intestinal neoplasia mice
Harpreet S. Wasan, Marco Novelli, Julie Bee, and Walter F. Bodmer
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3308–3313.
PMCID: PMC20365
Anti-viral protection conferred by recombinant adenylate cyclase toxins from Bordetella pertussis carrying a CD8+ T cell epitope from lymphocytic choriomeningitis virus
M. F. Saron, C. Fayolle, P. Sebo, D. Ladant, A. Ullmann, and C. Leclerc
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3314–3319.
PMCID: PMC20366
The CAG repeat within the androgen receptor gene and its relationship to prostate cancer
Edward Giovannucci, Meir J. Stampfer, Krishna Krithivas, Myles Brown, Adam Brufsky, James Talcott, Charles H. Hennekens, and Philip W. Kantoff
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3320–3323.
PMCID: PMC20367
Human lymphotoxin mutein lacks hypotensive activity but has higher in vivo antitumor activity than lymphotoxin or tumor necrosis factor
Mitsue Taniyama, Toshimi Morita, Yasuhiro Yamagishi, Akihisa Kato, Chinami Bando, Noriyuki Okawa, and Akira Kaji
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3324–3329.
PMCID: PMC20368
Development of medullary thyroid carcinoma in transgenic mice expressing the RET protooncogene altered by a multiple endocrine neoplasia type 2A mutation
Francine-Marie Michiels, Sophie Chappuis, Bernard Caillou, Andrea Pasini, Monique Talbot, Roger Monier, Gilbert M. Lenoir, Jean Feunteun, and Marc Billaud
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3330–3335.
PMCID: PMC20369
Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential
Masahiko Tsujii, Sunao Kawano, and Raymond N. DuBois
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3336–3340.
PMCID: PMC20370
Microbiology
Human cytomegalovirus IE1 and IE2 proteins are mutagenic and mediate “hit-and-run” oncogenic transformation in cooperation with the adenovirus E1A proteins
Yuqiao Shen, Hua Zhu, and Thomas Shenk
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3341–3345.
PMCID: PMC20371
Development of a novel anti-HIV-1 agent from within: Effect of chimeric Vpr-containing protease cleavage site residues on virus replication
D. Serio, T. A. Rizvi, M. Cartas, V. S. Kalyanaraman, I. T. Weber, H. Koprowski, and A. Srinivasan
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3346–3351.
PMCID: PMC20372
HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses
Richard P. Tomko, Ruliang Xu, and Lennart Philipson
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3352–3356.
PMCID: PMC20373
Neurobiology
Pituitary adenylate cyclase-activating polypeptide is an autocrine inhibitor of mitosis in cultured cortical precursor cells
Nairu Lu and Emanuel DiCicco-Bloom
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3357–3362.
PMCID: PMC20374
Induction of dopamine D3 receptor expression as a mechanism of behavioral sensitization to levodopa
Régis Bordet, Sophie Ridray, Suzanna Carboni, Jorge Diaz, Pierre Sokoloff, and Jean-Charles Schwartz
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3363–3367.
PMCID: PMC20375
Time-course changes of nerve growth factor, corticotropin-releasing hormone, and nitric oxide synthase isoforms and their possible role in the development of inflammatory response in experimental allergic encephalomyelitis
Laura Calzà, Luciana Giardino, Monica Pozza, Alessandra Micera, and Luigi Aloe
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3368–3373.
PMCID: PMC20376
Restrictive clonal allocation in the chimeric mouse brain
Chia-Yi Kuan, Eileen A. Elliott, Richard A. Flavell, and Pasko Rakic
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3374–3379.
PMCID: PMC20377
Age-dependent decrease of synaptic plasticity in the neocortex of αCaMKII mutant mice
Alfredo Kirkwood, Alcino Silva, and Mark F. Bear
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3380–3383.
PMCID: PMC20378
Guanylyl cyclase expression in specific sensory neurons: A new family of chemosensory receptors
Sidney Yu, Leon Avery, Eric Baude, and David L. Garbers
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3384–3387.
PMCID: PMC20379
A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway
Dawn M. Juilfs, Hans-Jürgen Fülle, Allan Z. Zhao, Miles D. Houslay, David L. Garbers, and Joseph A. Beavo
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3388–3395.
PMCID: PMC20380
Neuronal nitric oxide synthase alternatively spliced forms: Prominent functional localizations in the brain
Mikael J. L. Eliasson, Seth Blackshaw, Michael J. Schell, and Solomon H. Snyder
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3396–3401.
PMCID: PMC20381
Patterns of synaptic activity in neural networks recorded by light emission from synaptolucins
Gero Miesenböck and James E. Rothman
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3402–3407.
PMCID: PMC20382
The role of temporal cortical areas in perceptual organization
D. L. Sheinberg and N. K. Logothetis
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3408–3413.
PMCID: PMC20383
The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation
Laird Bloom and H. Robert Horvitz
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3414–3419.
PMCID: PMC20384
Pharmacology
Targeting E2F1–DNA complexes with microgonotropen DNA binding agents
Shu-Yuan Chiang, Thomas C. Bruice, Jane C. Azizkhan, Loretta Gawron, and Terry A. Beerman
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 2811–2816.
PMCID: PMC20278
Physiology
Variable expression of myoglobin among the hemoglobinless Antarctic icefishes
Bruce D. Sidell, Michael E. Vayda, Deena J. Small, Thomas J. Moylan, Richard L. Londraville, Meng-Lan Yuan, Kenneth J. Rodnick, Zoe A. Eppley, and Lori Costello
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3420–3424.
PMCID: PMC20385
Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution
Minglin Li, Xiuwen Liu, Gertraud Robinson, Ud Bar-Peled, Kay-Uwe Wagner, W. Scott Young, Lothar Hennighausen, and Priscilla A. Furth
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3425–3430.
PMCID: PMC20386
Plant Biology
Microcolinearity in sh2-homologous regions of the maize, rice, and sorghum genomes
M. Chen, P. SanMiguel, A. C. de Oliveira, S.-S. Woo, H. Zhang, R. A. Wing, and J. L. Bennetzen
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3431–3435.
PMCID: PMC20387
Lack of mitochondrial and nuclear-encoded subunits of complex I and alteration of the respiratory chain in Nicotiana sylvestris mitochondrial deletion mutants
Sophie Gutierres, Mohammed Sabar, Christine Lelandais, Philippe Chetrit, Philippe Diolez, Hervé Degand, Marc Boutry, Fernand Vedel, Yaroslav de Kouchkovsky, and Rosine De Paepe
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3436–3441.
PMCID: PMC20388
Transcriptional analysis of nucleolar dominance in polyploid plants: Biased expression/silencing of progenitor rRNA genes is developmentally regulated in Brassica
Z. Jeffrey Chen and Craig S. Pikaard
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3442–3447.
PMCID: PMC20389
Voltage-dependent gating characteristics of the K+ channel KAT1 depend on the N and C termini
Irene Marten and Toshinori Hoshi
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3448–3453.
PMCID: PMC20390
Choline monooxygenase, an unusual iron-sulfur enzyme catalyzing the first step of glycine betaine synthesis in plants: Prosthetic group characterization and cDNA cloning
Bala Rathinasabapathi, Michael Burnet, Brenda L. Russell, Douglas A. Gage, Pao-Chi Liao, Gordon J. Nye, Paul Scott, John H. Golbeck, and Andrew D. Hanson
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3454–3458.
PMCID: PMC20391
Hrp pilus: An hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000
Elina Roine, Wensheng Wei, Jing Yuan, Eeva-Liisa Nurmiaho-Lassila, Nisse Kalkkinen, Martin Romantschuk, and Sheng Yang He
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3459–3464.
PMCID: PMC20392
Multi-functional acetyl-CoA carboxylase from Brassica napus is encoded by a multi-gene family: Indication for plastidic localization of at least one isoform
Wolfgang Schulte, Reinhard Töpfer, Ralf Stracke, Jeff Schell, and Norbert Martini
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3465–3470.
PMCID: PMC20393
Population Biology
Centaurea corymbosa, a cliff-dwelling species tottering on the brink of extinction: A demographic and genetic study
Bruno Colas, Isabelle Olivieri, and Miquel Riba
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3471–3476.
PMCID: PMC20394
Social Sciences
Anthropology
Microsatellite diversity and the demographic history of modern humans
Lynn B. Jorde, Alan R. Rogers, Michael Bamshad, W. Scott Watkins, Patrycja Krakowiak, Sandy Sung, Juha Kere, and Henry C. Harpending
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3100–3103.
PMCID: PMC20328
Psychology
Reciprocal interactions between occlusion and motion computations
Barton L. Anderson and Pawan Sinha
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3477–3480.
PMCID: PMC20395
Correction
Proc Natl Acad Sci U S A. 1997 April 1; 94(7): 3481.
PMCID: PMC56126
Corrects: R Mollaaghababa, et al. Structure and function in rhodopsin: expression of functional mammalian opsin in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1996 October 15; 93(21): 11482–11486.
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