Effect of Systematic Medication Review in Elderly Patients Admitted to an Orthopedic Department - Tabular View

This Tabular View shows the required WHO registration data elements as marked by ^†

Tracking Information

First Received Date ^†

August 20, 2008

Last Updated Date

February 26, 2009

Start Date ^†

April 2009

Current Primary Outcome Measures ^†

Admission time for elderly patients 65 years and older admitted to an Orthopedic Department [ Time Frame: October 2009 ] [ Designated as safety issue: No ]

Original Primary Outcome Measures ^†

Same as current

Change History

Complete list of historical versions of study NCT00738816 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^†

Time to first unscheduled physician contact(general practitioner,emergency department, ambulatory care or re-admission to hospital) after discharge from the Orthopaedic Department [ Time Frame: 3 and 12 month after admission date ] [ Designated as safety issue: No ]

Original Secondary Outcome Measures ^†

Same as current

Descriptive Information

Brief Title ^†

Effect of Systematic Medication Review in Elderly Patients Admitted to an Orthopedic Department

Official Title ^†

The Effect of Systematic Medication Review in Elderly Patients Admitted to an Orthopedic Department.

Brief Summary

Elderly patients have a higher risk of experiencing adverse drug events due to an age related increase in morbidity and medication use. Inappropriate or wrong medication use among elderly patients acutely admitted to hospitals is assumed to result in earlier contact to general practitioner, emergency departments and re-admissions if not corrected during hospital admission. It is therefore our hypothesis that a systematic medication review conducted by pharmacists and physicians specialized in pharmacology will increase time to first unscheduled physician contact (general practitioner, emergency departments, ambulatory care and re-admissions) after discharge from hospital from an average of 21days to 25 days. Further, the following secondary outcome parameters will be measured at 3 and 12 month follow-up:

length of in-hospital stay
number of contacts to general practitioner 30 days after discharge, that resulted in medication changes
number of re-admissions at 3 and 12 month
number of death at 3 and 12 month
number of contact to primary health care at 3 and 12 month
patients self-experienced quality of health (EQ-5D)

Detailed Description

Study Phase

Study Type ^†

Interventional

Study Design ^†

Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Safety Study

Condition ^†

Elderly

Intervention ^†

Other: Systematic medication review and advisory notes

Study Arms / Comparison Groups

Other: Systematic medication review

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^†

Not yet recruiting

Enrollment ^†

100

Estimated Completion Date

April 2010

Estimated Primary Completion Date

October 2009 (final data collection date for primary outcome measure)

Eligibility Criteria ^†

Inclusion Criteria:

age 65 years or older
expected admission time of more than 24 hours
acute admission

Exclusion Criteria:

Psychotic patients
Moribund patients
Suicidal patients

Gender

Both

Ages

65 Years and older

Accepts Healthy Volunteers

Contacts ^††

Contact: Marianne Lisby, MHSc

+45 61264949

marilisb@rm.dk

Location Countries ^†

Denmark

Expanded Access Status

Administrative Information

NCT ID ^†

NCT00738816

Responsible Party

Marianne Lisby, Aarhus University Hospital

Secondary IDs ^††

Study Sponsor ^†

Aarhus University Hospital

Collaborators ^††

Investigators ^†

Principal Investigator:

Nielsen Lars Peter, Assoc. Prof.

Aarhus University Hospital, Denmark

Information Provided By

University of Aarhus

Verification Date

February 2009

^† Required WHO trial registration data element.
^†† WHO trial registration data element that is required only if it exists.