CGAP       the Cancer Genome Anatomy Project
    CGAP HOW TO GenesChromosomesTissuesSAGEPathwaysTools  

Genes

Gene Tools

SNP Tools

Transcriptome Analysis

CGAP Data

Purchase CGAP Reagents

Related Links

Quick Links:

NCI Logo


Gene Info

Gene Information For:Hs. APLP2, Amyloid beta (A4) precursor-like protein 2
Sequence ID:NM_001642

Database Links

UniGeneEntrez GeneOMIMSNPViewerAssemblies

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q23-q25|11q24Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 129519520 - 129519910

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820109Full LengthBC000373amyloid beta (A4) precursor-like protein 2
3640033Full LengthBC004371amyloid beta (A4) precursor-like protein 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001633  

Protein Infomation

RefSeq

mRNAProteinSwissProtPfam Motifs
NM_001642 NP_001633 Q06481 Kunitz_BPTI
A4_EXTRA

Related Sequences

 
mRNAGenPeptSwissProt
L09209 AAA35526 Q06481
L19597 AAA35601 Q06481
L23113 AAA36032 Q06481
L23114 AAA36130 Q06481
L27631 AAC41701 Q06481
S60099 AAC60589 Q06481
AF168956 AAD47291 Q06481
BC000373 AAH00373 Q06481
BC004371 AAH04371 Q06481
EU176627 ABW03428  
EU176299 ABW03750  
AK128162 BAG54641 B3KXX9
AK296765 BAG59345 B4DKY3
AK300378 BAG62113 B4DTV1
AK304736 BAG65497 B4E3I5
Z22572 CAA80295 Q06481

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens APLP2 NP_001633 R.norvegicus Aplp2 64312   XP_343514 94
M.musculus Aplp2 11804 Gene Info NP_033821 87
A.gambiae AgaP_AGAP002790 1273174   XP_312126 34
D.melanogaster Appl 31002   NP_476626 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)


If you have any questions, comments, or need information about CGAP, please contact the NCI CGAP Help Desk.