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Gene Info

Gene Information For:Hs. IDH2, Isocitrate dehydrogenase 2 (NADP+), mitochondrial
Sequence ID:NM_002168

Database Links

UniGeneEntrez GeneOMIMSNPViewerAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:15q26.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:15: 88428217 - 88446704

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2959540Full LengthBC009244isocitrate dehydrogenase 2 (NADP+), mitochondrial
6090792Full LengthBC071828isocitrate dehydrogenase 2 (NADP+), mitochondrial

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002159  

Protein Infomation

RefSeq

mRNAProteinSwissProtEnzymePfam Motifs
NM_002168 NP_002159 P48735 EC 1.1.1.42 Iso_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC009244 AAH09244 P48735 EC 1.1.1.42
BC071828 AAH71828 P48735 EC 1.1.1.42
DQ892817 ABM83743    
DQ896063 ABM87062    
AK222916 BAD96636 Q53GL5  
AK312627 BAG35513 B2R6L6  
AK294148 BAG57473 B4DFL2  
AK299987 BAG61808 B4DSZ6  
X69433 CAA49208 P48735 EC 1.1.1.42

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens IDH2 NP_002159 M.musculus Idh2 269951 Gene Info NP_766599 95
R.norvegicus Idh2 361596   NP_001014183 95
A.gambiae AgaP_AGAP003168 1273838   XP_312860 75
C.elegans C34F6.8 181311   NP_509875 69
A.thaliana ICDH 841875   NP_175836 69
S.cerevisiae IDP2 850871   NP_013275 65

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

Kegg Pathways
Pathway information courtesy of Kegg


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