Tirelli U, Vaccher E, Sinicco A, Sabbatani S, Guidici MG, Zagni R, Monfardini S; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 600 (abstract no. W.C.P.50).
Gruppo Italiano Cooperativo AIDS-Tumori (GICAT). Italy
OBJECTIVE: To evaluate the characteristics of unusual HIV-related tumors observed in Italy. RESULTS: Since 1986 the GICAT has collected 49 HIV-related tumors other than KS and NHL predominantly among intravenous drug abusers (IVDA), in accordance with the overall epidemiology of AIDS. TABULAR DATA, SEE ABSTRACT VOLUME. Only 1 case was reported of glioblastoma, thyroid ca., thymoma, melanoma, renal ca. pancreatic ca., CLL, CML, oral ca. (male polytransfused) and anal ca. (female prostitute with anal intercourse). Testis ca. occurred in patients (pts) mainly in early HIV infection without adversely affecting full dose chemotherapy or radiotherapy. Cervix ca. in 8/9 pts treated with conisation would suggest PAP test screening in young IVDA. Lung ca. occurred in a young age group with rapid progression and death within 2 mo. Intensive chemotherapy in Burkitt-like ALL was not adversely affected by HIV infection and 2 CR were achieved (11 and 15 mo. duration). CONCLUSION: In the IVDA-based series, while oral and anorectal tumors did not occur, there is a wide spectrum of unusual HIV-related tumors which is probably underestimated because not diagnostic of AIDS. The required therapeutic approach may not be consistently influenced by HIV infection, as for KS and NHL.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- Carcinoma
- Disease Progression
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Italy
- Male
- Melanoma
- Neoplasms
- Substance Abuse, Intravenous
- radiotherapy
Other ID:
UI: 102179059
From Meeting Abstracts