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Volume 98(18);  August 28, 2001
Commentaries
Two by two: The pairings of P-selectin and P-selectin glycoprotein ligand 1
Guy A. Zimmerman
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10023–10024. doi: 10.1073/pnas.191367898.
PMCID: PMC56905
Making sense (and antisense) of the X inactivation center
Huntington F. Willard and Laura Carrel
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10025–10027. doi: 10.1073/pnas.191380198.
PMCID: PMC56906
Targeted therapies for killing tumor cells
Adi F. Gazdar and John D. Minna
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10028–10030. doi: 10.1073/pnas.191379998.
PMCID: PMC56907
Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo
Gordon B. Mills, Yiling Lu, and Elise C. Kohn
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10031–10033. doi: 10.1073/pnas.191379498.
PMCID: PMC56908
CmC(a/t)GG methylation: A new epigenetic mark in mammalian DNA?
Matthew C. Lorincz and Mark Groudine
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10034–10036. doi: 10.1073/pnas.201392598.
PMCID: PMC56909
Physical Sciences
Applied Mathematics
The coreceptor mutation CCR5Δ32 influences the dynamics of HIV epidemics and is selected for by HIV
Amy D. Sullivan, Janis Wigginton, and Denise Kirschner
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10214–10219. Published online 2001 August 21. doi: 10.1073/pnas.181325198.
PMCID: PMC56941
Chemistry
Electrostatics of nanosystems: Application to microtubules and the ribosome
Nathan A. Baker, David Sept, Simpson Joseph, Michael J. Holst, and J. Andrew McCammon
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10037–10041. Published online 2001 August 21. doi: 10.1073/pnas.181342398.
PMCID: PMC56910
Chiral exciton coupling of merocyanine dyes within a well defined hydrogen-bonded assembly
Leonard J. Prins, Christoph Thalacker, Frank Würthner, Peter Timmerman, and David N. Reinhoudt
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10042–10045. doi: 10.1073/pnas.171131398.
PMCID: PMC56911
Biological Sciences
Applied Biological Sciences
The see-through medaka: A fish model that is transparent throughout life
Yuko Wakamatsu, Sergey Pristyazhnyuk, Masato Kinoshita, Minoru Tanaka, and Kenjiro Ozato
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10046–10050. doi: 10.1073/pnas.181204298.
PMCID: PMC56912
From the Cover:
The interplay of biology and technology
Stanley Fields
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10051–10054. Published online 2001 August 21. doi: 10.1073/pnas.191380098.
PMCID: PMC56913
Biochemistry
Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment
Hanne Hastrup, Arthur Karlin, and Jonathan A. Javitch
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10055–10060. doi: 10.1073/pnas.181344298.
PMCID: PMC56914
Phospholamban domain IB forms an interaction site with the loop between transmembrane helices M6 and M7 of sarco(endo)plasmic reticulum Ca2+ ATPases
Michio Asahi, N. Michael Green, Kazimierz Kurzydlowski, Michihiko Tada, and David H. MacLennan
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10061–10066. doi: 10.1073/pnas.181348298.
PMCID: PMC56915
Why multiple small subunits (Y2 and Y4) for yeast ribonucleotide reductase? Toward understanding the role of Y4
Jie Ge, Deborah L. Perlstein, Hiep-Hoa Nguyen, Galit Bar, Robert G. Griffin, and JoAnne Stubbe
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10067–10072. doi: 10.1073/pnas.181336498.
PMCID: PMC56916
Structure of the yeast ribonucleotide reductase Y2Y4 heterodimer
Walter C. Voegtli, Jie Ge, Deborah L. Perlstein, JoAnne Stubbe, and Amy C. Rosenzweig
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10073–10078. doi: 10.1073/pnas.181336398.
PMCID: PMC56917
Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants
Wolf-Rüdiger Scheible, Ravit Eshed, Todd Richmond, Deborah Delmer, and Chris Somerville
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10079–10084. Published online 2001 August 21. doi: 10.1073/pnas.191361598.
PMCID: PMC56918
Human DNA replication initiation factors, ORC and MCM, associate with oriP of Epstein–Barr virus
Biswendu Chaudhuri, Hongzhan Xu, Ivan Todorov, Anindya Dutta, and John L. Yates
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10085–10089. Published online 2001 August 21. doi: 10.1073/pnas.181347998.
PMCID: PMC56919
DNA binding induces dissociation of the multimeric form of HIV-1 integrase: A time-resolved fluorescence anisotropy study
Eric Deprez, Patrick Tauc, Hervé Leh, Jean-François Mouscadet, Christian Auclair, Mary E. Hawkins, and Jean-Claude Brochon
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10090–10095. Published online 2001 August 14. doi: 10.1073/pnas.181024498.
PMCID: PMC56920
From the Cover:
A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition
Mark A. Bayfield, Albert E. Dahlberg, Ulrike Schulmeister, Silke Dorner, and Andrea Barta
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10096–10101. Published online 2001 August 21. doi: 10.1073/pnas.171319598.
PMCID: PMC56921
Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase
Youwei Jiang, Aaron M. Cypess, Evan D. Muse, Cui-Rong Wu, Cecilia G. Unson, R. B. Merrifield, and Thomas P. Sakmar
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10102–10107. Published online 2001 August 21. doi: 10.1073/pnas.131200398.
PMCID: PMC56922
Flavohemoglobin denitrosylase catalyzes the reaction of a nitroxyl equivalent with molecular oxygen
Alfred Hausladen, Andrew Gow, and Jonathan S. Stamler
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10108–10112. Published online 2001 August 21. doi: 10.1073/pnas.181199698.
PMCID: PMC56923
DNA repair of a single UV photoproduct in a designed nucleosome
Joseph V. Kosmoski, Eric J. Ackerman, and Michael J. Smerdon
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10113–10118. Published online 2001 August 21. doi: 10.1073/pnas.181073398.
PMCID: PMC56924
A hemoglobin from plants homologous to truncated hemoglobins of microorganisms
R. A. Watts, P. W. Hunt, A. N. Hvitved, M. S. Hargrove, W. J. Peacock, and E. S. Dennis
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10119–10124. doi: 10.1073/pnas.191349198.
PMCID: PMC56925
Biophysics
Electrostatics of nanosystems: Application to microtubules and the ribosome
Nathan A. Baker, David Sept, Simpson Joseph, Michael J. Holst, and J. Andrew McCammon
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10037–10041. Published online 2001 August 21. doi: 10.1073/pnas.181342398.
PMCID: PMC56910
TOUCHSTONE: An ab initio protein structure prediction method that uses threading-based tertiary restraints
Daisuke Kihara, Hui Lu, Andrzej Kolinski, and Jeffrey Skolnick
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10125–10130. Published online 2001 August 14. doi: 10.1073/pnas.181328398.
PMCID: PMC56926
X-ray structure of sensory rhodopsin II at 2.1-Å resolution
Antoine Royant, Peter Nollert, Karl Edman, Richard Neutze, Ehud M. Landau, Eva Pebay-Peyroula, and Javier Navarro
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10131–10136. Published online 2001 August 14. doi: 10.1073/pnas.181203898.
PMCID: PMC56927
Partitioning of a polymer into a nanoscopic protein pore obeys a simple scaling law
Liviu Movileanu and Hagan Bayley
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10137–10141. Published online 2001 August 14. doi: 10.1073/pnas.181089798.
PMCID: PMC56928
Cell Biology
HIV envelope gp120 activates human arterial smooth muscle cells
Alison D. Schecter, Adriane B. Berman, Lin Yi, Arevik Mosoian, Carrie M. McManus, Joan W. Berman, Mary E. Klotman, and Mark B. Taubman
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10142–10147. Published online 2001 August 14. doi: 10.1073/pnas.181328798.
PMCID: PMC56929
Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation
Seiji Ura, Norihisa Masuyama, Jonathan D. Graves, and Yukiko Gotoh
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10148–10153. Published online 2001 August 21. doi: 10.1073/pnas.181161698.
PMCID: PMC56930
Transportin-SR2 mediates nuclear import of phosphorylated SR proteins
Ming-Chih Lai, Ru-Inn Lin, and Woan-Yuh Tarn
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10154–10159. Published online 2001 August 21. doi: 10.1073/pnas.181354098.
PMCID: PMC56931
Self-organization of a radial microtubule array by dynein-dependent nucleation of microtubules
Ivan Vorobjev, Viacheslav Malikov, and Vladimir Rodionov
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10160–10165. Published online 2001 August 14. doi: 10.1073/pnas.181354198.
PMCID: PMC56932
From the Cover:
Dimerization of a selectin and its ligand stabilizes cell rolling and enhances tether strength in shear flow
Vishwanath Ramachandran, Tadayuki Yago, Terry Kay Epperson, Marcin M. A. Kobzdej, Matthias U. Nollert, Richard D. Cummings, Cheng Zhu, and Rodger P. McEver
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10166–10171. Published online 2001 July 31. doi: 10.1073/pnas.171248098.
PMCID: PMC56933
Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis
Anatoly V. Grishin, Olga Azhipa, Igor Semenov, and Seth J. Corey
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10172–10177. Published online 2001 August 21. doi: 10.1073/pnas.191130798.
PMCID: PMC56934
A cell-based system that recapitulates the dynamic light-dependent regulation of the vertebrate clock
Matthew P. Pando, Anna B. Pinchak, Nicolas Cermakian, and Paolo Sassone-Corsi
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10178–10183. Published online 2001 August 21. doi: 10.1073/pnas.181228598.
PMCID: PMC56935
Developmental Biology
Regulation of SR protein localization during development
Jeremy R. Sanford and James P. Bruzik
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10184–10189. doi: 10.1073/pnas.181340498.
PMCID: PMC56936
Hemocytes are essential for wing maturation in Drosophila melanogaster
John A. Kiger, Jr., Jeanette E. Natzle, and M. M. Green
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10190–10195. Published online 2001 August 14. doi: 10.1073/pnas.181338998.
PMCID: PMC56937
Evolution
Expression and phylogeny of claudins in vertebrate primordia
Richard Kollmar, Shashi Karia Nakamura, James A. Kappler, and A. J. Hudspeth
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10196–10201. Published online 2001 August 21. doi: 10.1073/pnas.171325898.
PMCID: PMC56938
Molecular phylogenetic analyses of the mitochondrial ADP-ATP carriers: The Plantae/Fungi/Metazoa trichotomy revisited
Ari Löytynoja and Michel C. Milinkovitch
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10202–10207. Published online 2001 August 21. doi: 10.1073/pnas.181187698.
PMCID: PMC56939
From the Cover:
Accelerated regulatory gene evolution in an adaptive radiation
Marianne Barrier, Robert H. Robichaux, and Michael D. Purugganan
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10208–10213. Published online 2001 August 21. doi: 10.1073/pnas.181257698.
PMCID: PMC56940
Genetics
The coreceptor mutation CCR5Δ32 influences the dynamics of HIV epidemics and is selected for by HIV
Amy D. Sullivan, Janis Wigginton, and Denise Kirschner
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10214–10219. Published online 2001 August 21. doi: 10.1073/pnas.181325198.
PMCID: PMC56941
The tRNA function of SsrA contributes to controlling repression of bacteriophage Mu prophage
Caroline Ranquet, Johannes Geiselmann, and Ariane Toussaint
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10220–10225. Published online 2001 August 21. doi: 10.1073/pnas.171620598.
PMCID: PMC56942
Activation of β-major globin gene transcription is associated with recruitment of NF-E2 to the β-globin LCR and gene promoter
Tomoyuki Sawado, Kazuhiko Igarashi, and Mark Groudine
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10226–10231. Published online 2001 August 21. doi: 10.1073/pnas.181344198.
PMCID: PMC56943
A functional role for Tsix transcription in blocking Xist RNA accumulation but not in X-chromosome choice
Nicholas Stavropoulos, Naifung Lu, and Jeannie T. Lee
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10232–10237. Published online 2001 July 31. doi: 10.1073/pnas.171243598.
PMCID: PMC56944
Mutations in Mlph, encoding a member of the Rab effector family, cause the melanosome transport defects observed in leaden mice
Lydia E. Matesic, Richard Yip, Andreé E. Reuss, Deborah A. Swing, T. Norene O'Sullivan, Colin F. Fletcher, Neal G. Copeland, and Nancy A. Jenkins
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10238–10243. Published online 2001 August 14. doi: 10.1073/pnas.181336698.
PMCID: PMC56945
The Eurasian Heartland: A continental perspective on Y-chromosome diversity
R. Spencer Wells, Nadira Yuldasheva, Ruslan Ruzibakiev, Peter A. Underhill, Irina Evseeva, Jason Blue-Smith, Li Jin, Bing Su, Ramasamy Pitchappan, Sadagopal Shanmugalakshmi, Karuppiah Balakrishnan, Mark Read, Nathaniel M. Pearson, Tatiana Zerjal, Matthew T. Webster, Irakli Zholoshvili, Elena Jamarjashvili, Spartak Gambarov, Behrouz Nikbin, Ashur Dostiev, Ogonazar Aknazarov, Pierre Zalloua, Igor Tsoy, Mikhail Kitaev, Mirsaid Mirrakhimov, Ashir Chariev, and Walter F. Bodmer
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10244–10249. doi: 10.1073/pnas.171305098.
PMCID: PMC56946
The tumor spectrum in FHIT-deficient mice
Nicola Zanesi, Vincenzo Fidanza, Louise Y. Fong, Rita Mancini, Teresa Druck, Mauro Valtieri, Thomas Rüdiger, Peter A. McCue, Carlo M. Croce, and Kay Huebner
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10250–10255. Published online 2001 August 21. doi: 10.1073/pnas.191345898.
PMCID: PMC56947
Antibody targeting studies in a transgenic murine model of spontaneous colorectal tumors
Robert W. Wilkinson, Elizabeth L. Ross, Richard Poulsom, Mohammad Ilyas, Josef Straub, David Snary, Walter F. Bodmer, and Stephen J. Mather
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10256–10260. Published online 2001 August 21. doi: 10.1073/pnas.181353498.
PMCID: PMC56948
Immunology
Attributes of γδ intraepithelial lymphocytes as suggested by their transcriptional profile
Aude M. Fahrer, Yves Konigshofer, Elizabeth M. Kerr, Ghassan Ghandour, David H. Mack, Mark M. Davis, and Yueh-hsiu Chien
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10261–10266. doi: 10.1073/pnas.171320798.
PMCID: PMC56949
Notch1 confers a resistance to glucocorticoid-induced apoptosis on developing thymocytes by down-regulating SRG3 expression
Young I. Choi, Sung H. Jeon, Jiho Jang, Sunmi Han, Joong K. Kim, Heekyoung Chung, Han W. Lee, Hee-Y. Chung, Sang D. Park, and Rho H. Seong
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10267–10272. Published online 2001 August 14. doi: 10.1073/pnas.181076198.
PMCID: PMC56950
Immune hyporesponsiveness to amyloid β-peptide in amyloid precursor protein transgenic mice: Implications for the pathogenesis and treatment of Alzheimer's disease
Alon Monsonego, Ruth Maron, Victor Zota, Dennis J. Selkoe, and Howard L. Weiner
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10273–10278. Published online 2001 August 21. doi: 10.1073/pnas.191118298.
PMCID: PMC56951
Germinal center-associated nuclear protein (GANP) has a phosphorylation-dependent DNA-primase activity that is up-regulated in germinal center regions
Kazuhiko Kuwahara, Shinjirou Tomiyasu, Satoru Fujimura, Kazumi Nomura, Yan Xing, Noriko Nishiyama, Michio Ogawa, Shinobu Imajoh-Ohmi, Shunji Izuta, and Nobuo Sakaguchi
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10279–10283. doi: 10.1073/pnas.181335698.
PMCID: PMC56952
Cell adhesion regulates gene expression at translational checkpoints in human myeloid leukocytes
Tracey S. Mahoney, Andrew S. Weyrich, Dan A. Dixon, Thomas McIntyre, Stephen M. Prescott, and Guy A. Zimmerman
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10284–10289. Published online 2001 August 21. doi: 10.1073/pnas.181201398.
PMCID: PMC56953
A monoclonal cytolytic T-lymphocyte response observed in a melanoma patient vaccinated with a tumor-specific antigenic peptide encoded by gene MAGE-3
Pierre G. Coulie, Vaios Karanikas, Didier Colau, Christophe Lurquin, Claire Landry, Marie Marchand, Thierry Dorval, Vincent Brichard, and Thierry Boon
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10290–10295. Published online 2001 August 21. doi: 10.1073/pnas.161260098.
PMCID: PMC56954
The principle of delivery of T cell epitopes to antigen-presenting cells applied to peptides from influenza virus, ovalbumin, and hen egg lysozyme: Implications for peptide vaccination
Ingunn B. Rasmussen, Elin Lunde, Terje E. Michaelsen, Bjarne Bogen, and Inger Sandlie
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10296–10301. Published online 2001 August 21. doi: 10.1073/pnas.181336898.
PMCID: PMC56955
Discrepancy between ELISPOT IFN-γ secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life
Verena Rubio-Godoy, Valerie Dutoit, Donata Rimoldi, Danielle Lienard, Ferdy Lejeune, Daniel Speiser, Philippe Guillaume, Jean-Charles Cerottini, Pedro Romero, and Danila Valmori
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10302–10307. Published online 2001 August 21. doi: 10.1073/pnas.181348898.
PMCID: PMC56956
Medical Sciences
Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival
Hidemasa Oh, George E. Taffet, Keith A. Youker, Mark L. Entman, Paul A. Overbeek, Lloyd H. Michael, and Michael D. Schneider
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10308–10313. Published online 2001 August 21. doi: 10.1073/pnas.191169098.
PMCID: PMC56957
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
Mehran S. Neshat, Ingo K. Mellinghoff, Chris Tran, Bangyan Stiles, George Thomas, Roseann Petersen, Philip Frost, James J. Gibbons, Hong Wu, and Charles L. Sawyers
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10314–10319. Published online 2001 August 14. doi: 10.1073/pnas.171076798.
PMCID: PMC56958
An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/− mice
Katrina Podsypanina, Richard T. Lee, Chris Politis, Ian Hennessy, Allison Crane, Janusz Puc, Mehran Neshat, Hong Wang, Lin Yang, Jay Gibbons, Phil Frost, Valley Dreisbach, John Blenis, Zbigniew Gaciong, Peter Fisher, Charles Sawyers, Lora Hedrick-Ellenson, and Ramon Parsons
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10320–10325. Published online 2001 August 14. doi: 10.1073/pnas.171060098.
PMCID: PMC56959
Furin inhibition results in absent or decreased invasiveness and tumorigenicity of human cancer cells
Daniel E. Bassi, Ricardo Lopez De Cicco, Haleh Mahloogi, Stanley Zucker, Gary Thomas, and Andres J. P. Klein-Szanto
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10326–10331. Published online 2001 August 21. doi: 10.1073/pnas.191199198.
PMCID: PMC56960
A combinatorial approach for selectively inducing programmed cell death in human pancreatic cancer cells
Zao-zhong Su, Irina V. Lebedeva, Rahul V. Gopalkrishnan, Neil I. Goldstein, C. A. Stein, John C. Reed, Paul Dent, and Paul B. Fisher
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10332–10337. doi: 10.1073/pnas.171315198.
PMCID: PMC56961
Molecular emergence of acute myeloid leukemia during treatment for acute lymphoblastic leukemia
Javier G. Blanco, Thierry Dervieux, Mathew J. Edick, Perdeep K. Mehta, Jeffrey E. Rubnitz, Sheila Shurtleff, Susana C. Raimondi, Frederick G. Behm, Ching-Hon Pui, and Mary V. Relling
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10338–10343. doi: 10.1073/pnas.181199898.
PMCID: PMC56962
Mobilized bone marrow cells repair the infarcted heart, improving function and survival
Donald Orlic, Jan Kajstura, Stefano Chimenti, Federica Limana, Igor Jakoniuk, Federico Quaini, Bernardo Nadal-Ginard, David M. Bodine, Annarosa Leri, and Piero Anversa
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10344–10349. Published online 2001 August 14. doi: 10.1073/pnas.181177898.
PMCID: PMC56963
Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols
Sanjay Gupta, Kedar Hastak, Nihal Ahmad, Jonathan S. Lewin, and Hasan Mukhtar
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10350–10355. Published online 2001 August 14. doi: 10.1073/pnas.171326098.
PMCID: PMC56964
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
Thomas Brabletz, Andreas Jung, Simone Reu, Marc Porzner, Falk Hlubek, Leoni A. Kunz-Schughart, Ruth Knuechel, and Thomas Kirchner
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10356–10361. doi: 10.1073/pnas.171610498.
PMCID: PMC56965
HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals
Susan Moir, Angela Malaspina, Kisani M. Ogwaro, Eileen T. Donoghue, Claire W. Hallahan, Linda A. Ehler, Shuying Liu, Joseph Adelsberger, Réjean Lapointe, Patrick Hwu, Michael Baseler, Jan M. Orenstein, Tae-Wook Chun, Jo Ann M. Mican, and Anthony S. Fauci
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10362–10367. Published online 2001 August 14. doi: 10.1073/pnas.181347898.
PMCID: PMC56966
An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration
Johanna Lahdenranta, Renata Pasqualini, Reinier O. Schlingemann, Martin Hagedorn, William B. Stallcup, Corazon D. Bucana, Richard L. Sidman, and Wadih Arap
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10368–10373. doi: 10.1073/pnas.181329198.
PMCID: PMC56967
FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and regulates mitosis
Hideshi Ishii, Andrea Vecchione, Yoshiki Murakumo, Gustavo Baldassarre, Shinichiro Numata, Francesco Trapasso, Hansjuerg Alder, Raffaele Baffa, and Carlo M. Croce
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10374–10379. Published online 2001 August 14. doi: 10.1073/pnas.181222898.
PMCID: PMC56968
Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP function
Yijun Zhu, Chao Qi, Wen-Qing Cao, Anjana V. Yeldandi, M. Sambasiva Rao, and Janardan K. Reddy
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10380–10385. Published online 2001 August 21. doi: 10.1073/pnas.181347498.
PMCID: PMC56969
The nuclear factor kappa B (NF-κB): A potential therapeutic target for estrogen receptor negative breast cancers
Debajit K. Biswas, Sun-Chun Dai, Antonio Cruz, Barbara Weiser, Edgard Graner, and Arthur B. Pardee
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10386–10391. Published online 2001 August 21. doi: 10.1073/pnas.151257998.
PMCID: PMC56970
Characterization of key residues in the subdomain encoded by exons 8 and 9 of human inducible nitric oxide synthase: A critical role for Asp-280 in substrate binding and subunit interactions
Dipak K. Ghosh, Mohammad B. Rashid, Brian Crane, Varsha Taskar, Molly Mast, Mary A. Misukonis, J. Brice Weinberg, and N. Tony Eissa
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10392–10397. Published online 2001 August 21. doi: 10.1073/pnas.181251298.
PMCID: PMC56971
AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations
Youzhong Yuan, Liming Zhou, Toshihiro Miyamoto, Hiromi Iwasaki, Nari Harakawa, Christopher J. Hetherington, Sebastien A. Burel, Eric Lagasse, Irving L. Weissman, Koichi Akashi, and Dong-Er Zhang
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10398–10403. doi: 10.1073/pnas.171321298.
PMCID: PMC56972
CmC(A/T)GG DNA methylation in mature B cell lymphoma gene silencing
Cindy Sue Malone, Maurine D. Miner, Jeanette R. Doerr, James P. Jackson, Steven E. Jacobsen, Randolph Wall, and Michael Teitell
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10404–10409. Published online 2001 August 14. doi: 10.1073/pnas.181206898.
PMCID: PMC56973
Microbiology
The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins
Joshua Munger and Bernard Roizman
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10410–10415. Published online 2001 August 21. doi: 10.1073/pnas.181344498.
PMCID: PMC56974
Global differential gene expression in response to growth temperature alteration in group A Streptococcus
Laura M. Smoot, James C. Smoot, Morag R. Graham, Greg A. Somerville, Daniel E. Sturdevant, Cristi A. Lux Migliaccio, Gail L. Sylva, and James M. Musser
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10416–10421. Published online 2001 August 21. doi: 10.1073/pnas.191267598.
PMCID: PMC56975
Molecular characterization of a mannoprotein with homology to chitin deacetylases that stimulates T cell responses to Cryptococcus neoformans
Stuart M. Levitz, Shu-hua Nong, Michael K. Mansour, Chao Huang, and Charles A. Specht
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10422–10427. Published online 2001 August 14. doi: 10.1073/pnas.181331398.
PMCID: PMC56976
Neurobiology
Glutamate-induced transient modification of the postsynaptic density
Ayse Dosemeci, Jung-Hwa Tao-Cheng, Lucia Vinade, Christine A. Winters, Lucas Pozzo-Miller, and Thomas S. Reese
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10428–10432. Published online 2001 August 21. doi: 10.1073/pnas.181336998.
PMCID: PMC56977
Gene transfer of the JNK interacting protein-1 protects dopaminergic neurons in the MPTP model of Parkinson's disease
Xu Gang Xia, Thomas Harding, Michael Weller, Alison Bieneman, James B. Uney, and Jörg B. Schulz
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10433–10438. Published online 2001 August 14. doi: 10.1073/pnas.181182298.
PMCID: PMC56978
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
Jonathan D. Cooper, Ahmad Salehi, Jean-Dominique Delcroix, Charles L. Howe, Pavel V. Belichenko, Jane Chua-Couzens, Joshua F. Kilbridge, Elaine J. Carlson, Charles J. Epstein, and William C. Mobley
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10439–10444. Published online 2001 August 14. doi: 10.1073/pnas.181219298.
PMCID: PMC56979
Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways
James Yager, Stephen Richards, Daria S. Hekmat-Scafe, Daryl D. Hurd, Vanathi Sundaresan, David R. Caprette, William M. Saxton, John R. Carlson, and Michael Stern
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10445–10450. Published online 2001 August 21. doi: 10.1073/pnas.191107698.
PMCID: PMC56980
Induction of stereotypy in dopamine-deficient mice requires striatal D1 receptor activation
Elena H. Chartoff, Brett T. Marck, Alvin M. Matsumoto, Daniel M. Dorsa, and Richard D. Palmiter
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10451–10456. Published online 2001 August 21. doi: 10.1073/pnas.181356498.
PMCID: PMC56981
Noninvasive neuroelectronic interfacing with synaptically connected snail neurons immobilized on a semiconductor chip
Günther Zeck and Peter Fromherz
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10457–10462. doi: 10.1073/pnas.181348698.
PMCID: PMC56982
Plastic neural changes and reading improvement caused by audiovisual training in reading-impaired children
T. Kujala, K. Karma, R. Ceponiene, S. Belitz, P. Turkkila, M. Tervaniemi, and R. Näätänen
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10509–10514. Published online 2001 August 21. doi: 10.1073/pnas.181589198.
PMCID: PMC56991
Pharmacology
Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling
Nazareno Paolocci, Walter F. Saavedra, Katrina M. Miranda, Cristian Martignani, Takayoshi Isoda, Joshua M. Hare, Michael G. Espey, Jon M. Fukuto, Martin Feelisch, David A. Wink, and David A. Kass
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10463–10468. Published online 2001 August 21. doi: 10.1073/pnas.181191198.
PMCID: PMC56983
Physiology
Does oxidative damage to DNA increase with age?
Michelle L. Hamilton, Holly Van Remmen, Jessica A. Drake, Hong Yang, Zhong Mao Guo, Kristen Kewitt, Christi A. Walter, and Arlan Richardson
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10469–10474. Published online 2001 August 21. doi: 10.1073/pnas.171202698.
PMCID: PMC56984
Basolateral membrane expression of a K+ channel, Kir 2.3, is directed by a cytoplasmic COOH-terminal domain
Sophie Le Maout, Paul A. Welling, Manuel Brejon, Olav Olsen, and Jean Merot
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10475–10480. Published online 2001 August 14. doi: 10.1073/pnas.181481098.
PMCID: PMC56985
Plant Biology
cAMP acts as a second messenger in pollen tube growth and reorientation
Ana Moutinho, Patrick J. Hussey, Anthony J. Trewavas, and Rui Malhó
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10481–10486. Published online 2001 August 21. doi: 10.1073/pnas.171104598.
PMCID: PMC56986
Regulation of plant growth by cytokinin
Tomáš Werner, Václav Motyka, Miroslav Strnad, and Thomas Schmülling
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10487–10492. Published online 2001 August 14. doi: 10.1073/pnas.171304098.
PMCID: PMC56987
Intragenic recombination generated two distinct Cf genes that mediate AVR9 recognition in the natural population of Lycopersicon pimpinellifolium
Renier A. L. Van der Hoorn, Marco Kruijt, Ronelle Roth, Bas F. Brandwagt, Matthieu H. A. J. Joosten, and Pierre J. G. M. De Wit
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10493–10498. Published online 2001 August 21. doi: 10.1073/pnas.181241798.
PMCID: PMC56988
An essential role of a TatC homologue of a ΔpH- dependent protein transporter in thylakoid membrane formation during chloroplast development in Arabidopsis thaliana
Reiko Motohashi, Noriko Nagata, Takuya Ito, Seiji Takahashi, Tokunori Hobo, Shigeo Yoshida, and Kazuo Shinozaki
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10499–10504. doi: 10.1073/pnas.181304598.
PMCID: PMC56989
Population Biology
From the Cover:
A genome-wide scan for linkage to human exceptional longevity identifies a locus on chromosome 4
Annibale A. Puca, Mark J. Daly, Stephanie J. Brewster, Tara C. Matise, Jeffrey Barrett, Maureen Shea-Drinkwater, Sammy Kang, Erin Joyce, Julie Nicoli, Erica Benson, Louis M. Kunkel, and Thomas Perls
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10505–10508. Published online 2001 August 27. doi: 10.1073/pnas.181337598.
PMCID: PMC56990
Social Sciences
Psychology
Plastic neural changes and reading improvement caused by audiovisual training in reading-impaired children
T. Kujala, K. Karma, R. Ceponiene, S. Belitz, P. Turkkila, M. Tervaniemi, and R. Näätänen
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10509–10514. Published online 2001 August 21. doi: 10.1073/pnas.181589198.
PMCID: PMC56991
Corrections
Correction
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10515. Published online 2001 August 21.
PMCID: PMC56992
Corrects: P. D. Calvert, et al. Phototransduction in transgenic mice after targeted deletion of the rod transducin α-subunit. Proc Natl Acad Sci U S A. 2000 December 5; 97(25): 13913–13918.
Correction
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10515. Published online 2001 August 14.
PMCID: PMC56993
Corrects: Virginia Goss Tusher, et al. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A. 2001 April 24; 98(9): 5116–5121.
Correction
Proc Natl Acad Sci U S A. 2001 August 28; 98(18): 10515. Published online 2001 August 14.
PMCID: PMC56994
Corrects: Takashi Sugawara, et al. A missense mutation of the Na+ channel αII subunit gene Nav1.2 in a patient with febrile and afebrile seizures causes channel dysfunction. Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6384–6389.
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