Ochsendorf F, Schofer H, Milbradt R; International Conference on AIDS.
Int Conf AIDS. 1989 Jun 4-9; 5: 251 (abstract no. M.B.P.180).
Klinikum J.W.Goethe-Universitat, Dept. of Dermatology, Frankfurt, FRG
OBJECTIVE: To investigate whether cutaneous diseases, regarded as "non-infectious" up to now, allow a clinical evaluation of the stage of HIV-infection. METHODS: Over a 4-years-period, 267 HIV-infected patients (254 male, 13 female) were examined 4 times on an average. At first manifestation of a skin disorder, stage of HIV-infection and CD 4-counts were recorded. RESULTS: On entry of the study the mean CD 4-count was 407/mul. TABULAR DATA, SEE ABSTRACT VOLUME. 13 patients (4,9%) had lesions typical of psoriasis vulgaris. On progression of the disease in 6/9 cases CD-4 counts were lower than 200/mul. CONCLUSION: "Non-opportunistic" dermatoses were more frequent and severe in advanced stages of HIV-infection and increased with decreasing CD 4-counts. So they were a reliable clinical marker of cellular immunodeficiency indicating the risk of the individual for severe opportunistic infections.
Publication Types:
Keywords:
- Acquired Immunodeficiency Syndrome
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Disease Progression
- Female
- HIV Infections
- HIV Seropositivity
- Humans
- Male
- Psoriasis
- Skin Diseases
- T-Lymphocytes
Other ID:
UI: 102177034
From Meeting Abstracts