| | This journal provides immediate access to some articles. Colloquium Papers Multiplicity results for the Yamabe problem on Sn Antonio Ambrosetti Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15252–15256. Published online 2002 October 24. doi: 10.1073/pnas.222494199.PMCID: PMC137702 Solitary waves and Bohmian mechanics Alberto Abbondandolo and Vieri Benci Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15257–15261. Published online 2002 October 23. doi: 10.1073/pnas.222494299.PMCID: PMC137703 On the global Cauchy problem for the nonlinear
Schrödinger equation Jean Bourgain Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15262–15268. Published online 2002 November 13. doi: 10.1073/pnas.222494399.PMCID: PMC137704 Non-Lipschitz minimizers of smooth uniformly convex functionals Vladimír Sverák and Xiaodong Yan Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15269–15276. Published online 2002 October 28. doi: 10.1073/pnas.222494699.PMCID: PMC137705 Crystalline variational methods Jean E. Taylor Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15277–15280. Published online 2002 November 11. doi: 10.1073/pnas.222494799.PMCID: PMC137706 Elliptic Yang–Mills equation Gang Tian Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15281–15286. Published online 2002 November 8. doi: 10.1073/pnas.222494899.PMCID: PMC137707 Some nonlinear elliptic equations from geometry YanYan Li Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15287–15290. Published online 2002 November 20. doi: 10.1073/pnas.222494999.PMCID: PMC137708 Commentaries Fungus-farming insects: Multiple origins and diverse evolutionary histories Ulrich G. Mueller and Nicole Gerardo Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15247–15249. Published online 2002 November 18. doi: 10.1073/pnas.242594799.PMCID: PMC137700 Statistical learning in infants Gerry T. M. Altmann Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15250–15251. Published online 2002 November 18. doi: 10.1073/pnas.262659399.PMCID: PMC137701 Physical Sciences Applied Mathematics Quantifying predictability in a model with statistical features of the atmosphere Richard Kleeman, Andrew J. Majda, and Ilya Timofeyev Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15291–15296. Published online 2002 November 12. doi: 10.1073/pnas.192583699.PMCID: PMC137709 Chemistry Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin Samir Kumar Pal, Jorge Peon, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15297–15302. Published online 2002 November 11. doi: 10.1073/pnas.242600399.PMCID: PMC137710 Are helionitronium trications stable? Wolfgang Eisfeld and Joseph S. Francisco Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15303–15307. Published online 2002 November 12. doi: 10.1073/pnas.242490299.PMCID: PMC137711 Peroxone chemistry: Formation of H2O3 and ring-(HO2)(HO3) from O3/H2O2 Xin Xu and William A. Goddard, III Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15308–15312. Published online 2002 November 18. doi: 10.1073/pnas.202596799.PMCID: PMC137712 Invisible liposomes: Refractive index matching with sucrose enables flow dichroism assessment of peptide orientation in lipid vesicle membrane Malin Ardhammar, Per Lincoln, and Bengt Nordén Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15313–15317. Published online 2002 November 6. doi: 10.1073/pnas.192583499.PMCID: PMC137713 Engineering Gaussian curvature and the equilibrium among bilayer cylinders, spheres, and discs H.-T. Jung, S. Y. Lee, E. W. Kaler, B. Coldren, and J. A. Zasadzinski Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15318–15322. Published online 2002 November 20. doi: 10.1073/pnas.242374499.PMCID: PMC137714 Geology From the Cover: Low-magnesium calcite produced by coralline algae in seawater of Late Cretaceous composition Steven M. Stanley, Justin B. Ries, and Lawrence A. Hardie Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15323–15326. Published online 2002 October 24. doi: 10.1073/pnas.232569499.PMCID: PMC137715 Biological Sciences Biochemistry Escherichia coli RecO protein anneals ssDNA complexed with its cognate ssDNA-binding protein: A common step in genetic recombination Noriko Kantake, Murty V. V. M. Madiraju, Tomohiko Sugiyama, and Stephen C. Kowalczykowski Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15327–15332. Published online 2002 November 18. doi: 10.1073/pnas.252633399.PMCID: PMC137716 Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction R. Pawlinski, A. Fernandes, B. Kehrle, B. Pedersen, G. Parry, J. Erlich, R. Pyo, D. Gutstein, J. Zhang, F. Castellino, E. Melis, P. Carmeliet, G. Baretton, T. Luther, M. Taubman, E. Rosen, and N. Mackman Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15333–15338. Published online 2002 November 8. doi: 10.1073/pnas.242501899.PMCID: PMC137717 Early stages of energy transduction by myosin: Roles of Arg in Switch I, of Glu in Switch II, and of the salt-bridge between them Hirofumi Onishi, Takashi Ohki, Naoki Mochizuki, and Manuel F. Morales Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15339–15344. Published online 2002 November 12. doi: 10.1073/pnas.242604099.PMCID: PMC137718 Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA R. A. Neese, L. M. Misell, S. Turner, A. Chu, J. Kim, D. Cesar, R. Hoh, F. Antelo, A. Strawford, J. M. McCune, M. Christiansen, and M. K. Hellerstein Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15345–15350. Published online 2002 November 7. doi: 10.1073/pnas.232551499.PMCID: PMC137719 Structure of factor-inhibiting hypoxia-inducible factor 1: An asparaginyl hydroxylase involved in the hypoxic response pathway Charles E. Dann, III, Richard K. Bruick, and Johann Deisenhofer Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15351–15356. Published online 2002 November 13. doi: 10.1073/pnas.202614999.PMCID: PMC137720 Structure and function from the circadian clock protein KaiA of Synechococcus elongatus: A potential clock input mechanism Stanly B. Williams, Ioannis Vakonakis, Susan S. Golden, and Andy C. LiWang Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15357–15362. Published online 2002 November 15. doi: 10.1073/pnas.232517099.PMCID: PMC137721 Identification in Drosophila melanogaster of the invertebrate G protein-coupled FMRFamide receptor Tom Meeusen, Inge Mertens, Elke Clynen, Geert Baggerman, Ruthann Nichols, Ronald J. Nachman, Roger Huybrechts, Arnold De Loof, and Liliane Schoofs Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15363–15368. Published online 2002 November 18. doi: 10.1073/pnas.252339599.PMCID: PMC137722 Crystal structure of a human aminoacyl-tRNA synthetase cytokine Xiang-Lei Yang, Robert J. Skene, Duncan E. McRee, and Paul Schimmel Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15369–15374. Published online 2002 November 11. doi: 10.1073/pnas.242611799.PMCID: PMC137723 Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase Douglas A. Whittington, Mitchell L. Wise, Marek Urbansky, Robert M. Coates, Rodney B. Croteau, and David W. Christianson Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15375–15380. Published online 2002 November 13. doi: 10.1073/pnas.232591099.PMCID: PMC137724 SWI/SNF-dependent long-range remodeling of yeast HIS3 chromatin Yeonjung Kim and David J. Clark Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15381–15386. Published online 2002 November 13. doi: 10.1073/pnas.242536699.PMCID: PMC137725 The mechanism of topoisomerase I poisoning by a camptothecin analog Bart L. Staker, Kathryn Hjerrild, Michael D. Feese, Craig A. Behnke, Alex B. Burgin, Jr., and Lance Stewart Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15387–15392. Published online 2002 November 8. doi: 10.1073/pnas.242259599.PMCID: PMC137726 Biophysics Ultrafast surface hydration dynamics and expression of protein functionality: α-Chymotrypsin Samir Kumar Pal, Jorge Peon, and Ahmed H. Zewail Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15297–15302. Published online 2002 November 11. doi: 10.1073/pnas.242600399.PMCID: PMC137710 Invisible liposomes: Refractive index matching with sucrose enables flow dichroism assessment of peptide orientation in lipid vesicle membrane Malin Ardhammar, Per Lincoln, and Bengt Nordén Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15313–15317. Published online 2002 November 6. doi: 10.1073/pnas.192583499.PMCID: PMC137713 From the Cover: Mitotic chromosomes are chromatin networks without a mechanically contiguous protein scaffold Michael G. Poirier and John F. Marko Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15393–15397. Published online 2002 November 18. doi: 10.1073/pnas.232442599.PMCID: PMC137727 The substrate binding domain of DnaK facilitates slow protein refolding Naoki Tanaka, Shota Nakao, Hiromasa Wadai, Shoichi Ikeda, Jean Chatellier, and Shigeru Kunugi Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15398–15403. Published online 2002 November 14. doi: 10.1073/pnas.242317099.PMCID: PMC137728 Control of biochemical reactions through supramolecular RING domain self-assembly Alex Kentsis, Ronald E. Gordon, and Katherine L. B. Borden Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15404–15409. Published online 2002 November 18. doi: 10.1073/pnas.202608799.PMCID: PMC137729 Conformational-relaxation models of single-enzyme kinetics Hans-Philipp Lerch, Alexander S. Mikhailov, and Benno Hess Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15410–15415. Published online 2002 November 12. doi: 10.1073/pnas.232376799.PMCID: PMC137730 Circular dichroism spectra of short, fixed-nucleus alanine helices Der-Hang Chin, Robert W. Woody, Carol A. Rohl, and Robert L. Baldwin Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15416–15421. Published online 2002 November 11. doi: 10.1073/pnas.232591399.PMCID: PMC137731 Cell Biology Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI Thomas J. F. Nieland, Marsha Penman, Limor Dori, Monty Krieger, and Tomas Kirchhausen Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15422–15427. Published online 2002 November 18. doi: 10.1073/pnas.222421399.PMCID: PMC137732 Chemical chaperones increase the cellular activity of N370S β-glucosidase: A therapeutic strategy for Gaucher disease Anu R. Sawkar, Wei-Chieh Cheng, Ernest Beutler, Chi-Huey Wong, William E. Balch, and Jeffery W. Kelly Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15428–15433. Published online 2002 November 14. doi: 10.1073/pnas.192582899.PMCID: PMC137733 Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins Karina Barseguian, Bart Lutterbach, Scott W. Hiebert, Jeffrey Nickerson, Jane B. Lian, Janet L. Stein, Andre J. van Wijnen, and Gary S. Stein Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15434–15439. Published online 2002 November 11. doi: 10.1073/pnas.242588499.PMCID: PMC137734 Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A Laurie E. Littlepage, Hua Wu, Thorkell Andresson, Julia K. Deanehan, Laufey T. Amundadottir, and Joan V. Ruderman Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15440–15445. Published online 2002 November 6. doi: 10.1073/pnas.202606599.PMCID: PMC137735 Developmental Biology Bombyxin is a growth factor for wing imaginal disks in Lepidoptera H. Frederik Nijhout and Laura W. Grunert Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15446–15450. Published online 2002 November 12. doi: 10.1073/pnas.242548399.PMCID: PMC137736 Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells Thaddeus S. Stappenbeck, Lora V. Hooper, and Jeffrey I. Gordon Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15451–15455. Published online 2002 November 13. doi: 10.1073/pnas.202604299.PMCID: PMC137737 Pineal expression-promoting element (PIPE), a cis-acting element, directs pineal-specific gene expression in zebrafish Yoichi Asaoka, Hiroaki Mano, Daisuke Kojima, and Yoshitaka Fukada Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15456–15461. Published online 2002 November 18. doi: 10.1073/pnas.232444199.PMCID: PMC137738 Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland M. P. Postiglione, R. Parlato, A. Rodriguez-Mallon, A. Rosica, P. Mithbaokar, M. Maresca, R. C. Marians, T. F. Davies, M. S. Zannini, M. De Felice, and R. Di Lauro Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15462–15467. Published online 2002 November 13. doi: 10.1073/pnas.242328999.PMCID: PMC137739 Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells Chang-Zheng Chen, Min Li, David de Graaf, Stefano Monti, Berthold Göttgens, Maria-Jose Sanchez, Eric S. Lander, Todd R. Golub, Anthony R. Green, and Harvey F. Lodish Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15468–15473. Published online 2002 November 15. doi: 10.1073/pnas.202614899.PMCID: PMC137740 Activin A induces craniofacial cartilage from undifferentiated Xenopus ectoderm in vitro Miho Furue, Yasufumi Myoishi, Yasuto Fukui, Takashi Ariizumi, Tetsuji Okamoto, and Makoto Asashima Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15474–15479. Published online 2002 November 7. doi: 10.1073/pnas.242597399.PMCID: PMC137741 Two isoforms of the Notch antagonist Hairless are produced by differential translation initiation Dieter Maier, Anja C. Nagel, and Anette Preiss Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15480–15485. Published online 2002 November 6. doi: 10.1073/pnas.242596699.PMCID: PMC137742 Ecology Altered host plant volatiles are proxies for sex pheromones in the gall wasp Antistrophus rufus John F. Tooker, Wilfried A. Koenig, and Lawrence M. Hanks Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15486–15491. Published online 2002 November 18. doi: 10.1073/pnas.252626799.PMCID: PMC137743 A computational method for resequencing long DNA targets by universal oligonucleotide arrays Itsik Pe'er, Naama Arbili, and Ron Shamir Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15492–15496. Published online 2002 November 12. doi: 10.1073/pnas.232278299.PMCID: PMC137744 Linking climate change and biological invasions: Ocean warming facilitates nonindigenous species invasions John J. Stachowicz, Jeffrey R. Terwin, Robert B. Whitlatch, and Richard W. Osman Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15497–15500. Published online 2002 November 6. doi: 10.1073/pnas.242437499.PMCID: PMC137745 Evolution The effect of selection on a long wavelength-sensitive (LWS) opsin gene of Lake Victoria cichlid fishes Yohey Terai, Werner E. Mayer, Jan Klein, Herbert Tichy, and Norihiro Okada Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15501–15506. Published online 2002 November 15. doi: 10.1073/pnas.232561099.PMCID: PMC137746 From the Cover: The single, ancient origin of chromist plastids Hwan Su Yoon, Jeremiah D. Hackett, Gabriele Pinto, and Debashish Bhattacharya Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15507–15512. Published online 2002 November 15. doi: 10.1073/pnas.242379899.PMCID: PMC137747 The signal of ancient introns is obscured by intron density and homolog number Scott William Roy, Alexei Fedorov, and Walter Gilbert Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15513–15517. Published online 2002 November 13. doi: 10.1073/pnas.242600199.PMCID: PMC137748 A general population genetic theory for the evolution of developmental interactions Sean H. Rice Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15518–15523. Published online 2002 November 18. doi: 10.1073/pnas.202620999.PMCID: PMC137749 Genetics Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia George Adrian Calin, Calin Dan Dumitru, Masayoshi Shimizu, Roberta Bichi, Simona Zupo, Evan Noch, Hansjuerg Aldler, Sashi Rattan, Michael Keating, Kanti Rai, Laura Rassenti, Thomas Kipps, Massimo Negrini, Florencia Bullrich, and Carlo M. Croce Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15524–15529. Published online 2002 November 14. doi: 10.1073/pnas.242606799.PMCID: PMC137750 Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae Adam M. Deutschbauer, Roy M. Williams, Angela M. Chu, and Ronald W. Davis Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15530–15535. Published online 2002 November 13. doi: 10.1073/pnas.202604399.PMCID: PMC137751 Transcriptional profiling of a mouse model for Rett syndrome reveals subtle transcriptional changes in the brain Matthew Tudor, Schahram Akbarian, Richard Z. Chen, and Rudolf Jaenisch Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15536–15541. Published online 2002 November 13. doi: 10.1073/pnas.242566899.PMCID: PMC137752 An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells Jay L. Vivian, Yijing Chen, Della Yee, Elizabeth Schneider, and Terry Magnuson Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15542–15547. Published online 2002 November 13. doi: 10.1073/pnas.242474199.PMCID: PMC137753 Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene Tomoo Ogi, Yoichi Shinkai, Kiyoji Tanaka, and Haruo Ohmori Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15548–15553. Published online 2002 November 13. doi: 10.1073/pnas.222377899.PMCID: PMC137754 Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements C. Melissa Dobson, Timothy Wai, Daniel Leclerc, Aaron Wilson, Xuchu Wu, Carole Doré, Thomas Hudson, David S. Rosenblatt, and Roy A. Gravel Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15554–15559. Published online 2002 November 15. doi: 10.1073/pnas.242614799.PMCID: PMC137755 High incidence of epithelial cancers in mice deficient for DNA polymerase δ proofreading Robert E. Goldsby, Laura E. Hays, Xin Chen, Elise A. Olmsted, William B. Slayton, Gerry J. Spangrude, and Bradley D. Preston Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15560–15565. Published online 2002 November 12. doi: 10.1073/pnas.232340999.PMCID: PMC137756 Immunology RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes Pau Serra, Abdelaziz Amrani, Bingye Han, Jun Yamanouchi, Shari J. Thiessen, and Pere Santamaria Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15566–15571. Published online 2002 November 13. doi: 10.1073/pnas.242321099.PMCID: PMC137757 In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: Why are CD4+ but not CD8+ T cells depleted? Ruy M. Ribeiro, Hiroshi Mohri, David D. Ho, and Alan S. Perelson Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15572–15577. Published online 2002 November 14. doi: 10.1073/pnas.242358099.PMCID: PMC137758 Medical Sciences Involvement of estrogen receptor β in terminal differentiation of mammary gland epithelium Carola Förster, Sari Mäkela, Anni Wärri, Silke Kietz, David Becker, Kjell Hultenby, Margaret Warner, and Jan-Åke Gustafsson Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15578–15583. Published online 2002 November 18. doi: 10.1073/pnas.192561299.PMCID: PMC137759 INAUGURAL ARTICLE by a Recently Elected Academy Member: A comparison of the molecular clock of hepatitis C virus in the United States and Japan predicts that hepatocellular carcinoma incidence in the United States will increase over the next two decades Yasuhito Tanaka, Kousuke Hanada, Masashi Mizokami, Anthony E. T. Yeo, J. Wai-Kuo Shih, Takashi Gojobori, and Harvey J. Alter Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15584–15589. Published online 2002 November 18. doi: 10.1073/pnas.242608099.PMCID: PMC137760 Cell surface CCR5 density determines the postentry efficiency of R5 HIV-1 infection Yea-Lih Lin, Clément Mettling, Pierre Portales, Jacques Reynes, Jacques Clot, and Pierre Corbeau Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15590–15595. Published online 2002 November 14. doi: 10.1073/pnas.242134499.PMCID: PMC137761 Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy Helen Vlassara, Weijing Cai, Jill Crandall, Teresia Goldberg, Robert Oberstein, Veronique Dardaine, Melpomeni Peppa, and Elliot J. Rayfield Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15596–15601. Published online 2002 November 12. doi: 10.1073/pnas.242407999.PMCID: PMC137762 The hemochromatosis protein HFE inhibits iron export from macrophages Hal Drakesmith, Emma Sweetland, Lisa Schimanski, Jon Edwards, Diana Cowley, Mubeen Ashraf, Judy Bastin, and Alain R. M. Townsend Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15602–15607. Published online 2002 November 12. doi: 10.1073/pnas.242614699.PMCID: PMC137763 Noninvasive imaging of protein–protein interactions in living subjects by using reporter protein complementation and reconstitution strategies R. Paulmurugan, Y. Umezawa, and S. S. Gambhir Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15608–15613. Published online 2002 November 18. doi: 10.1073/pnas.242594299.PMCID: PMC137764 Targeting the Mycobacterium tuberculosis 30/32-kDa mycolyl transferase complex as a therapeutic strategy against tuberculosis: Proof of principle by using antisense technology Günter Harth, Marcus A. Horwitz, David Tabatadze, and Paul C. Zamecnik Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15614–15619. Published online 2002 November 11. doi: 10.1073/pnas.242612299.PMCID: PMC137765 Neuroprotective autoimmunity: Naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system Jonathan Kipnis, Tal Mizrahi, Ehud Hauben, Iftach Shaked, Ethan Shevach, and Michal Schwartz Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15620–15625. Published online 2002 November 12. doi: 10.1073/pnas.232565399.PMCID: PMC137766 A genomic-scale view of the cAMP response element-enhancer decoy: A tumor target-based genetic tool Yee Sook Cho, Meyoung-Kon Kim, Chris Cheadle, Catherine Neary, Yun Gyu Park, Kevin G. Becker, and Yoon S. Cho-Chung Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15626–15631. Published online 2002 November 18. doi: 10.1073/pnas.242617799.PMCID: PMC137767 Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53 Heejei Yoon, Sandya Liyanarachchi, Fred A. Wright, Ramana Davuluri, Janet C. Lockman, Albert de la Chapelle, and Natalia S. Pellegata Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15632–15637. Published online 2002 November 15. doi: 10.1073/pnas.242597299.PMCID: PMC137768 Measurements of endothelial cell-to-cell and cell-to-substrate gaps and micromechanical properties of endothelial cells during monocyte adhesion Noriyuki Kataoka, Kanso Iwaki, Ken Hashimoto, Seiichi Mochizuki, Yasuo Ogasawara, Masaaki Sato, Katsuhiko Tsujioka, and Fumihiko Kajiya Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15638–15643. Published online 2002 November 14. doi: 10.1073/pnas.242590799.PMCID: PMC137769 Progesterone receptor knockout mice have an improved glucose homeostasis secondary to β-cell proliferation Frédéric Picard, Mitsuhiro Wanatabe, Kristina Schoonjans, John Lydon, Bert W. O'Malley, and Johan Auwerx Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15644–15648. Published online 2002 November 15. doi: 10.1073/pnas.202612199.PMCID: PMC137770 The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria Johan W. Jonker, Marije Buitelaar, Els Wagenaar, Martin A. van der Valk, George L. Scheffer, Rik J. Scheper, Torsten Plösch, Folkert Kuipers, Ronald P. J. Oude Elferink, Hilde Rosing, Jos H. Beijnen, and Alfred H. Schinkel Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15649–15654. Published online 2002 November 12. doi: 10.1073/pnas.202607599.PMCID: PMC137771 Microbiology Infection of a human hepatoma cell line by hepatitis B virus Philippe Gripon, Sylvie Rumin, Stephan Urban, Jacques Le Seyec, Denise Glaise, Isabelle Cannie, Claire Guyomard, Josette Lucas, Christian Trepo, and Christiane Guguen-Guillouzo Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15655–15660. Published online 2002 November 13. doi: 10.1073/pnas.232137699.PMCID: PMC137772 INAUGURAL ARTICLE by a Recently Elected Academy Member: Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease Robert Thimme, Jens Bukh, Hans Christian Spangenberg, Stefan Wieland, Janell Pemberton, Carola Steiger, Sugantha Govindarajan, Robert H. Purcell, and Francis V. Chisari Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15661–15668. Published online 2002 November 19. doi: 10.1073/pnas.202608299.PMCID: PMC137773 Genomic analysis of the host response to hepatitis C virus infection Andrew I. Su, John P. Pezacki, Lisa Wodicka, Amy D. Brideau, Lubica Supekova, Robert Thimme, Stefan Wieland, Jens Bukh, Robert H. Purcell, Peter G. Schultz, and Francis V. Chisari Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15669–15674. Published online 2002 November 19. doi: 10.1073/pnas.202608199.PMCID: PMC137774 Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis Eleftherios Mylonakis, Frederick M. Ausubel, John R. Perfect, Joseph Heitman, and Stephen B. Calderwood Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15675–15680. Published online 2002 November 15. doi: 10.1073/pnas.232568599.PMCID: PMC137775 Cultivating the uncultured Karsten Zengler, Gerardo Toledo, Michael Rappé, James Elkins, Eric J. Mathur, Jay M. Short, and Martin Keller Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15681–15686. Published online 2002 November 18. doi: 10.1073/pnas.252630999.PMCID: PMC137776 Microarray-based detection and genotyping of viral pathogens David Wang, Laurent Coscoy, Maxine Zylberberg, Pedro C. Avila, Homer A. Boushey, Don Ganem, and Joseph L. DeRisi Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15687–15692. Published online 2002 November 12. doi: 10.1073/pnas.242579699.PMCID: PMC137777 Membrane localization of MinD is mediated by a C-terminal motif that is conserved across eubacteria, archaea, and chloroplasts Tim H. Szeto, Susan L. Rowland, Lawrence I. Rothfield, and Glenn F. King Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15693–15698. Published online 2002 November 7. doi: 10.1073/pnas.232590599.PMCID: PMC137778 A simple alfalfa seedling infection model for Pseudomonas aeruginosa strains associated with cystic fibrosis shows AlgT (sigma-22) and RhlR contribute to pathogenesis Laura Silo-Suh, Sang-Jin Suh, Pamela A. Sokol, and Dennis E. Ohman Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15699–15704. Published online 2002 November 8. doi: 10.1073/pnas.242343999.PMCID: PMC137779 Host–pathogen interactions: Host resistance factor Nramp1 up-regulates the expression of Salmonella pathogenicity island-2 virulence genes Michelle L. Zaharik, Bruce A. Vallance, José L. Puente, Philippe Gros, and B. Brett Finlay Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15705–15710. Published online 2002 November 19. doi: 10.1073/pnas.252415599.PMCID: PMC137780 The analysis of the intramacrophagic virulome of Brucella suis deciphers the environment encountered by the pathogen inside the macrophage host cell Stephan Köhler, Vincent Foulongne, Safia Ouahrani-Bettache, Gisèle Bourg, Jacques Teyssier, Michel Ramuz, and Jean-Pierre Liautard Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15711–15716. Published online 2002 November 18. doi: 10.1073/pnas.232454299.PMCID: PMC137781 Neuroscience An exchanger-like protein underlies the large Mg2+ current in Paramecium W. John Haynes, Ching Kung, Yoshiro Saimi, and Robin R. Preston Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15717–15722. Published online 2002 November 6. doi: 10.1073/pnas.242603999.PMCID: PMC137782 Neurovestibular modulation of circadian and homeostatic regulation: Vestibulohypothalamic connection? Patrick M. Fuller, Timothy A. Jones, Sherri M. Jones, and Charles A. Fuller Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15723–15728. Published online 2002 November 14. doi: 10.1073/pnas.242251499.PMCID: PMC137783 Disrupted synaptic development in the hypoxic newborn brain Sheila M. Curristin, Anjun Cao, William B. Stewart, Heping Zhang, Joseph A. Madri, Jon S. Morrow, and Laura R. Ment Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15729–15734. Published online 2002 November 15. doi: 10.1073/pnas.232568799.PMCID: PMC137784 INAUGURAL ARTICLE by a Recently Elected Academy Member: Optical imaging reveals retinotopic organization of dorsal V3 in New World owl monkeys David C. Lyon, Xiangmin Xu, Vivien A. Casagrande, James D. Stefansic, Daniel Shima, and Jon H. Kaas Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15735–15742. Published online 2002 November 19. doi: 10.1073/pnas.242600699.PMCID: PMC137785 Reorganization of the cochleotopic map in the bat's auditory system by inhibition Zhongju Xiao and Nobuo Suga Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15743–15748. Published online 2002 November 5. doi: 10.1073/pnas.242606699.PMCID: PMC137786 Intracerebroventricular corticotropin-releasing factor increases limbic glucose metabolism and has social context-dependent behavioral effects in nonhuman primates Elissa M. Strome, G. H. Trevor Wheler, J. Dee Higley, D. Lynn Loriaux, Stephen J. Suomi, and Doris J. Doudet Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15749–15754. Published online 2002 November 18. doi: 10.1073/pnas.232480899.PMCID: PMC137787 Auditory looming perception in rhesus monkeys Asif A. Ghazanfar, John G. Neuhoff, and Nikos K. Logothetis Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15755–15757. Published online 2002 November 12. doi: 10.1073/pnas.242469699.PMCID: PMC137788 Increased rates of cerebral glucose metabolism in a mouse model of fragile X mental retardation Mei Qin, Julia Kang, and Carolyn Beebe Smith Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15758–15763. Published online 2002 November 11. doi: 10.1073/pnas.242377399.PMCID: PMC137789 Fast synaptic transmission between striatal spiny projection neurons Uwe Czubayko and Dietmar Plenz Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15764–15769. Published online 2002 November 18. doi: 10.1073/pnas.242428599.PMCID: PMC137790 Pharmacology NCX-1015, a nitric-oxide derivative of prednisolone, enhances regulatory T cells in the lamina propria and protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis in mice Stefano Fiorucci, Elisabetta Antonelli, Eleonora Distrutti, Piero Del Soldato, Roderick J. Flower, Mark J. Paul Clark, Antonio Morelli, Mauro Perretti, and Louis J. Ignarro Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15770–15775. Published online 2002 November 11. doi: 10.1073/pnas.232583599.PMCID: PMC137791 Physiology Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice R. C. Marians, L. Ng, H. C. Blair, P. Unger, P. N. Graves, and T. F. Davies Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15776–15781. Published online 2002 November 13. doi: 10.1073/pnas.242322099.PMCID: PMC137792 Kidney-specific chloride channel, OmClC-K, predominantly expressed in the diluting segment of freshwater-adapted tilapia kidney Hiroaki Miyazaki, Toyoji Kaneko, Shinichi Uchida, Sei Sasaki, and Yoshio Takei Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15782–15787. Published online 2002 November 11. doi: 10.1073/pnas.242611099.PMCID: PMC137793 Plant Biology KaiA-stimulated KaiC phosphorylation in circadian timing loops in cyanobacteria Hideo Iwasaki, Taeko Nishiwaki, Yohko Kitayama, Masato Nakajima, and Takao Kondo Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15788–15793. Published online 2002 October 21. doi: 10.1073/pnas.222467299.PMCID: PMC137794 Visualization by comprehensive microarray analysis of gene expression programs during transdifferentiation of mesophyll cells into xylem cells Taku Demura, Gen Tashiro, Gorou Horiguchi, Naoki Kishimoto, Minoru Kubo, Naoko Matsuoka, Atsushi Minami, Miyo Nagata-Hiwatashi, Keiko Nakamura, Yoshimichi Okamura, Naomi Sassa, Shinsuke Suzuki, Junshi Yazaki, Shoshi Kikuchi, and Hiroo Fukuda Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15794–15799. Published online 2002 November 18. doi: 10.1073/pnas.232590499.PMCID: PMC137795 An Arabidopsis histidine kinase is essential for megagametogenesis Melissa S. Pischke, Linda G. Jones, Denichiro Otsuga, Donna E. Fernandez, Gary N. Drews, and Michael R. Sussman Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15800–15805. Published online 2002 November 8. doi: 10.1073/pnas.232580499.PMCID: PMC137796 A chloroplast FKBP interacts with and affects the accumulation of Rieske subunit of cytochrome bf complex Rajeev Gupta, Ruth M. Mould, Zengyong He, and Sheng Luan Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15806–15811. Published online 2002 November 7. doi: 10.1073/pnas.222550399.PMCID: PMC137797 Mitogen-activated protein kinase signaling in postgermination arrest of development by abscisic acid C. Lu, M.-H. Han, A. Guevara-Garcia, and N. V. Fedoroff Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15812–15817. Published online 2002 November 14. doi: 10.1073/pnas.242607499.PMCID: PMC137798 The systemin precursor gene regulates both defensive and developmental genes in Solanum tuberosum Javier Narváez-Vásquez and Clarence A. Ryan, Jr. Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15818–15821. Published online 2002 November 8. doi: 10.1073/pnas.232591199.PMCID: PMC137799 Psychology (Biological Sciences) From the Cover: Statistical learning of new visual feature combinations by infants József Fiser and Richard N. Aslin Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15822–15826. Published online 2002 November 12. doi: 10.1073/pnas.232472899.PMCID: PMC137800 Social Sciences Economic Sciences Testing neoclassical competitive market theory in the field John A. List Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15827–15830. Published online 2002 November 13. doi: 10.1073/pnas.202602999.PMCID: PMC137801 Corrections Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 13. doi: 10.1073/pnas.242625699.PMCID: PMC137696 Corrects: Carol M. Kiekhaefer, et al. Hematopoietic-specific activators establish an overlapping pattern of histone acetylation and methylation within a mammalian chromatin domain. Proc Natl Acad Sci U S A. 2002 October 29; 99(22): 14309–14314. Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 11. doi: 10.1073/pnas.252628999.PMCID: PMC137697 Corrects: Linh Hoang, et al. Cytochrome c folding pathway: Kinetic native-state hydrogen exchange. Proc Natl Acad Sci U S A. 2002 September 17; 99(19): 12173–12178. Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 18. doi: 10.1073/pnas.222515899.PMCID: PMC137698 Corrects: Daniel J. Battle, et al. From the Cover: Specificity of RNA–RNA helix recognition. Proc Natl Acad Sci U S A. 2002 September 3; 99(18): 11676–11681. Proc Natl Acad Sci U S A. 2002 November 26; 99(24): 15831. Published online 2002 November 12. doi: 10.1073/pnas.232531999.PMCID: PMC137699 Corrects: Andreas Heise, et al. Two immediate-early pathogen-responsive members of the AtCMPG gene family in Arabidopsis thaliana and the W-box-containing elicitor-response element of AtCMPG1. Proc Natl Acad Sci U S A. 2002 June 25; 99(13): 9049–9054. |