Rethinking cell structure.

The causes and prevention of cancer.

Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension.

Symbiotic induction of a MADS-box gene during development of alfalfa root nodules.

Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America.

Structural variety of arginine-rich RNA-binding peptides.

Tumorigenic activity of the BCR-ABL oncogenes is mediated by BCL2.

Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation.

Direct measurement of hydrogen bonding in DNA nucleotide bases by atomic force microscopy.

Efficient high-resolution genetic mapping of mouse interspersed repetitive sequence PCR products, toward integrated genetic and physical mapping of the mouse genome.

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

Local nitric oxide production in viral and autoimmune diseases of the central nervous system.

A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids.

Dynamics of active lamellae in cultured epithelial cells: effects of expression of exogenous N-ras oncogene.

The folding of GroEL-bound barnase as a model for chaperonin-mediated protein folding.

Restriction fragment length polymorphism-coupled domain-directed differential display: a highly efficient technique for expression analysis of multigene families.

Pax5 (BSAP) regulates the murine immunoglobulin 3' alpha enhancer by suppressing binding of NF-alpha P, a protein that controls heavy chain transcription.

Age-related learning deficits in transgenic mice expressing the 751-amino acid isoform of human beta-amyloid precursor protein.

Inflammation-induced recombinant protein expression in vivo using promoters from acute-phase protein genes.

Purification and identification of pituitary cytotropic factor.

DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene.

Phosphorylation of the human leukemia inhibitory factor (LIF) receptor by mitogen-activated protein kinase and the regulation of LIF receptor function by heterologous receptor activation.

Full-length myotonin protein kinase (72 kDa) displays serine kinase activity.

Position-dependent variegation of globin transgene expression in mice.

Chimeric tumor necrosis factor receptors with constitutive signaling activity.

Inhibition of human immunodeficiency virus replication by nonimmunosuppressive analogs of cyclosporin A.

Cyclins as markers of tumor proliferation: immunocytochemical studies in breast cancer.

Scavenger receptor A gene regulatory elements target gene expression to macrophages and to foam cells of atherosclerotic lesions.

Two Drosophila nervous system antigens, Nervana 1 and 2, are homologous to the beta subunit of Na+,K(+)-ATPase.

Interferon gamma signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain.

Complex flexibility of the transforming growth factor beta superfamily.

Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum.

Identification of functionally important helical faces in transmembrane segments by scanning mutagenesis.

Enhanced secretion of glycocholic acid in a specially adapted cell line is associated with overexpression of apparently novel ATP-binding cassette proteins.

Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs.

Translational termination efficiency in mammals is influenced by the base following the stop codon.

Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

Drosophila 5-HT2 serotonin receptor: coexpression with fushi-tarazu during segmentation.

Structure and stability of a second molten globule intermediate in the apomyoglobin folding pathway.

Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

Binding of purified multiple antibiotic-resistance repressor protein (MarR) to mar operator sequences.

Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1.

Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure.

Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with other HIV-1-specific inhibitors (i.e., TSAO derivatives).

Grasshopper crop and midgut extract effects on plants: an example of reward feedback.

The dietary adaptations of European Miocene catarrhines.

Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.

Adaptive reversion of an episomal frameshift mutation in Escherichia coli requires conjugal functions but not actual conjugation.

Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division.

The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver.

Reduced surface expression of transforming growth factor beta receptor type II in mitogen-activated T cells from Sézary patients.

A simple test of the vicarious trial-and-error hypothesis of hippocampal function.

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments.

A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3.

Misexpression of the white (w) gene triggers male-male courtship in Drosophila.

Neural-network-based classification of cognitively normal, demented, Alzheimer disease and vascular dementia from single photon emission with computed tomography image data from brain.

Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2.

Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination.

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism.

Operational RNA code for amino acids: species-specific aminoacylation of minihelices switched by a single nucleotide.

Sticky ions in biological systems.

A class of single-stranded telomeric DNA-binding proteins required for Rap1p localization in yeast nuclei.

Human immunodeficiency virus 1 reservoir in CD4+ T cells is restricted to certain V beta subsets.

Induction of intracellular cAMP by a synthetic retroviral envelope peptide: a possible mechanism of immunopathogenesis in retroviral infections.

Genomic DNA fingerprinting by restriction fragment end labeling.

Emergent spindle oscillations and intermittent burst firing in a thalamic model: specific neuronal mechanisms.

Mechanisms underlying the sensitivity of songbird forebrain neurons to temporal order.

Cortical correlate of pattern backward masking.

Vector-mediated delivery of a polyamide ("peptide") nucleic acid analogue through the blood-brain barrier in vivo.

Significant discrepancies between van't Hoff and calorimetric enthalpies.

The N-terminal region (A/B) of rat thyroid hormone receptors alpha 1, beta 1, but not beta 2 contains a strong thyroid hormone-dependent transactivation function.

Accelerated evolution in the protein-coding regions is universal in crotalinae snake venom gland phospholipase A2 isozyme genes.

Direct detection and isolation of restriction landmark genomic scanning (RLGS) spot DNA markers tightly linked to a specific trait by using the RLGS spot-bombing method.

Transient transfection and expression of firefly luciferase in Giardia lamblia.

Evidence for five divergent thioredoxin h sequences in Arabidopsis thaliana.

Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences.

Identification of a plastid protein involved in vesicle fusion and/or membrane protein translocation.

RuvC protein resolves Holliday junctions via cleavage of the continuous (noncrossover) strands.

Rep protein of tomato yellow leaf curl geminivirus has an ATPase activity required for viral DNA replication.

Combinatorial association and abundance of components of interferon-stimulated gene factor 3 dictate the selectivity of interferon responses.

Low concentrations of diacylglycerol promote the binding of apolipophorin III to a phospholipid bilayer: a surface plasmon resonance spectroscopy study.

Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.

Mitochondrial DNA replication but no nuclear DNA replication during development of Dictyostelium.

Yeast histone H3 and H4 N termini function through different GAL1 regulatory elements to repress and activate transcription.

Adaptive mutations in Escherichia coli as a model for the multiple mutational origins of tumors.

Cytotoxic T-lymphocyte clones from different patients display limited T-cell-receptor variable-region gene usage in HLA-A2-restricted recognition of the melanoma antigen Melan-A/MART-1.

Natural killer and lymphokine-activated killer cells require granzyme B for the rapid induction of apoptosis in susceptible target cells.

Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitis.

Blockade of T- and B-lymphocyte development by antibody to the gamma c subunit of the receptors for interleukins 2, 4, and 7.

Human immunodeficiency virus type 1 reverse transcriptase: enhancement of activity by interaction with cellular topoisomerase I.

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system.

Construction and characterization of a highly complex retroviral library for lineage analysis.

Deregulated expression of PAX5 in medulloblastoma.

The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction.

DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors.

Elevated expression of H type GDP-L-fucose:beta-D-galactoside alpha-2-L-fucosyltransferase is associated with human colon adenocarcinoma progression.

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity.

Somatodendritic expression of an immediate early gene is regulated by synaptic activity.

Redistribution of synaptic vesicles and their proteins in temperature-sensitive shibire(ts1) mutant Drosophila.

Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylation.

Insertional mutagenesis and marker rescue in a protozoan parasite: cloning of the uracil phosphoribosyltransferase locus from Toxoplasma gondii.

Endogenous mutagenesis by an insertion sequence element identifies Aeromonas salmonicida AbcA as an ATP-binding cassette transport protein required for biogenesis of smooth lipopolysaccharide.

PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae

Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain