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Volume 98(17);  August 14, 2001
Commentaries
Do mRNAs act as direct sensors of small molecules to control their expression?
Gary D. Stormo and Yongmei Ji
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9465–9467. doi: 10.1073/pnas.181334498.
PMCID: PMC55472
Multidisciplinary dissection of behavioral arousal: The role of muscarinic acetylcholine stimulation in grasshopper stridulatory behavior
Moira J. van Staaden and Robert Huber
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9468–9470. doi: 10.1073/pnas.181341098.
PMCID: PMC55473
Flotillas of lipid rafts fore and aft
Lynda M. Pierini and Frederick R. Maxfield
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9471–9473. doi: 10.1073/pnas.181353098.
PMCID: PMC55474
Following the trace of elusive amines
Richard T. Premont, Raul R. Gainetdinov, and Marc G. Caron
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9474–9475. doi: 10.1073/pnas.181356198.
PMCID: PMC55475
Physical Sciences
Applied Mathematics
An Eulerian path approach to DNA fragment assembly
Pavel A. Pevzner, Haixu Tang, and Michael S. Waterman
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9748–9753. doi: 10.1073/pnas.171285098.
PMCID: PMC55524
Astronomy
Theoretical emission line ratios for [Fe III] and [Fe VII] applicable to the optical and infrared spectra of gaseous nebulae
Francis P. Keenan, Lawrence H. Aller, Robert S. I. Ryans, and Siek Hyung
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9476–9477. Published online 2001 August 7. doi: 10.1073/pnas.151263098.
PMCID: PMC55476
Chemistry
Interchain hydrogen-bonding interactions may facilitate translocation of K+ ions across the potassium channel selectivity filter, as suggested by synthetic modeling chemistry
Juan C. Mareque Rivas, Harald Schwalbe, and Stephen J. Lippard
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9478–9483. doi: 10.1073/pnas.161257798.
PMCID: PMC55477
Geophysics
Aggregate sound velocities and acoustic Grüneisen parameter of iron up to 300 GPa and 1,200 K
L. S. Dubrovinsky, N. A. Dubrovinskaia, and T. Le Bihan
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9484–9489. doi: 10.1073/pnas.161583398.
PMCID: PMC55478
Physics
Quantum optical implementation of Grover's algorithm
Marlan O. Scully and M. S. Zubairy
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9490–9493. doi: 10.1073/pnas.171317798.
PMCID: PMC55479
Biological Sciences
Biochemistry
Interchain hydrogen-bonding interactions may facilitate translocation of K+ ions across the potassium channel selectivity filter, as suggested by synthetic modeling chemistry
Juan C. Mareque Rivas, Harald Schwalbe, and Stephen J. Lippard
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9478–9483. doi: 10.1073/pnas.161257798.
PMCID: PMC55477
Formation of a selenium-substituted rhodanese by reaction with selenite and glutathione: Possible role of a protein perselenide in a selenium delivery system
Yuki Ogasawara, Gerard Lacourciere, and Thressa C. Stadtman
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9494–9498. Published online 2001 August 7. doi: 10.1073/pnas.171320998.
PMCID: PMC55480
Characterization of an adapter subunit to a phosphatidylinositol (3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity
H. H. Nandurkar, K. K. Caldwell, J. C. Whisstock, M. J. Layton, E. A. Gaudet, F. A. Norris, P. W. Majerus, and C. A. Mitchell
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9499–9504. doi: 10.1073/pnas.171306098.
PMCID: PMC55481
Mitochondria play no roles in Mn(II)-induced apoptosis in HeLa cells
Hammou Oubrahim, Earl R. Stadtman, and P. Boon Chock
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9505–9510. Published online 2001 August 7. doi: 10.1073/pnas.181319898.
PMCID: PMC55482
A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist
Wenfeng Xu, Scott R. Presnell, Julia Parrish-Novak, Wayne Kindsvogel, Steve Jaspers, Zhi Chen, Stacey R. Dillon, Zeren Gao, Teresa Gilbert, Karen Madden, Stacy Schlutsmeyer, Lena Yao, Theodore E. Whitmore, Yasmin Chandrasekher, Francis J. Grant, Mark Maurer, Laura Jelinek, Harold Storey, Ty Brender, Angie Hammond, Stavros Topouzis, Christopher H. Clegg, and Donald C. Foster
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9511–9516. Published online 2001 July 31. doi: 10.1073/pnas.171303198.
PMCID: PMC55483
Propagating conformational changes over long (and short) distances in proteins
Edward W. Yu and Daniel E. Koshland, Jr.
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9517–9520. doi: 10.1073/pnas.161239298.
PMCID: PMC55484
Mapping the interactions between flavodoxin and its physiological partners flavodoxin reductase and cobalamin-dependent methionine synthase
Diane A. Hall, Craig W. Vander Kooi, Chad N. Stasik, Shawn Y. Stevens, Erik R. P. Zuiderweg, and Rowena G. Matthews
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9521–9526. Published online 2001 August 7. doi: 10.1073/pnas.171168898.
PMCID: PMC55485
The active site dynamics of 4-chlorobenzoyl-CoA dehalogenase
Edmond Y. Lau and Thomas C. Bruice
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9527–9532. Published online 2001 August 7. doi: 10.1073/pnas.161282698.
PMCID: PMC55486
Three-dimensional structure of a mammalian thioredoxin reductase: Implications for mechanism and evolution of a selenocysteine-dependent enzyme
Tatyana Sandalova, Liangwei Zhong, Ylva Lindqvist, Arne Holmgren, and Gunter Schneider
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9533–9538. Published online 2001 July 31. doi: 10.1073/pnas.171178698.
PMCID: PMC55487
Mechanism of transfer of NO from extracellular S-nitrosothiols into the cytosol by cell-surface protein disulfide isomerase
Niroshan Ramachandran, Paul Root, Xing-Mai Jiang, Phillip J. Hogg, and Bulent Mutus
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9539–9544. Published online 2001 August 7. doi: 10.1073/pnas.171180998.
PMCID: PMC55488
Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells
Douglas A. Whittington, Abdul Waheed, Barbara Ulmasov, Gul N. Shah, Jeffrey H. Grubb, William S. Sly, and David W. Christianson
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9545–9550. Published online 2001 August 7. doi: 10.1073/pnas.161301298.
PMCID: PMC55489
DsbC activation by the N-terminal domain of DsbD
David Goldstone, Peter W. Haebel, Federico Katzen, Martin W. Bader, James C. A. Bardwell, Jon Beckwith, and Peter Metcalf
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9551–9556. Published online 2001 August 7. doi: 10.1073/pnas.171315498.
PMCID: PMC55490
Structure of the gene 2.5 protein, a single-stranded DNA binding protein encoded by bacteriophage T7
Thomas Hollis, James M. Stattel, Dane S. Walther, Charles C. Richardson, and Tom Ellenberger
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9557–9562. Published online 2001 July 31. doi: 10.1073/pnas.171317698.
PMCID: PMC55491
A Drosophila PIAS homologue negatively regulates stat92E
Aurel Betz, Nina Lampen, Sebastian Martinek, Michael W. Young, and James E. Darnell, Jr.
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9563–9568. doi: 10.1073/pnas.171302098.
PMCID: PMC55492
Mechanism of termination of DNA replication of Escherichia coli involves helicase–contrahelicase interaction
Sashidhar Mulugu, Aardra Potnis, Shamsuzzaman, Jeffery Taylor, Ken Alexander, and Deepak Bastia
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9569–9574. Published online 2001 August 7. doi: 10.1073/pnas.171065898.
PMCID: PMC55493
Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21WAF1/CIP1 expression in keratinocyte differentiation
Maria Paola Santini, Claudio Talora, Toshihiko Seki, Loretta Bolgan, and G. Paolo Dotto
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9575–9580. Published online 2001 August 7. doi: 10.1073/pnas.161299698.
PMCID: PMC55494
Kinetic trapping of DNA by transcription factor IIIB
Timothy E. Cloutier, Monett D. Librizzi, A. K. M. M. Mollah, Michael Brenowitz, and Ian M. Willis
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9581–9586. Published online 2001 July 31. doi: 10.1073/pnas.161292298.
PMCID: PMC55495
BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor
Lei Zheng, Lois A. Annab, Cynthia A. Afshari, Wen-Hwa Lee, and Thomas G. Boyer
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9587–9592. Published online 2001 August 7. doi: 10.1073/pnas.171174298.
PMCID: PMC55496
A metallothionein containing a zinc finger within a four-metal cluster protects a bacterium from zinc toxicity
Claudia A. Blindauer, Mark D. Harrison, John A. Parkinson, Andrea K. Robinson, Jennifer S. Cavet, Nigel J. Robinson, and Peter J. Sadler
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9593–9598. Published online 2001 August 7. doi: 10.1073/pnas.171120098.
PMCID: PMC55497
Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κB
Guozhong Gong, Gulam Waris, Rasheeda Tanveer, and Aleem Siddiqui
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9599–9604. Published online 2001 July 31. doi: 10.1073/pnas.171311298.
PMCID: PMC55498
Activation and autoregulation of DNA-PK from structured single-stranded DNA and coding end hairpins
Sébastien Soubeyrand, Heather Torrance, Ward Giffin, Wenrong Gong, Caroline Schild-Poulter, and Robert J. G. Haché
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9605–9610. Published online 2001 July 31. doi: 10.1073/pnas.171211398.
PMCID: PMC55499
Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine kinases in human NK cells upon CD16 engagement
Rossella Paolini, Rosa Molfetta, Mario Piccoli, Luigi Frati, and Angela Santoni
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9611–9616. Published online 2001 August 7. doi: 10.1073/pnas.161298098.
PMCID: PMC55500
Biophysics
Periodic perturbations in Shaker K+ channel gating kinetics by deletions in the S3–S4 linker
Carlos Gonzalez, Eduardo Rosenman, Francisco Bezanilla, Osvaldo Alvarez, and Ramon Latorre
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9617–9623. Published online 2001 August 7. doi: 10.1073/pnas.171306298.
PMCID: PMC55501
Highly selective water channel activity measured by voltage clamp: Analysis of planar lipid bilayers reconstituted with purified AqpZ
Peter Pohl, Sapar M. Saparov, Mario J. Borgnia, and Peter Agre
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9624–9629. Published online 2001 August 7. doi: 10.1073/pnas.161299398.
PMCID: PMC55502
Cell Biology
HIF-1α binding to VHL is regulated by stimulus-sensitive proline hydroxylation
Fang Yu, Sarah B. White, Quan Zhao, and Frank S. Lee
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9630–9635. doi: 10.1073/pnas.181341498.
PMCID: PMC55503
A novel mammalian receptor for the evolutionarily conserved type II GnRH
Robert Millar, Steven Lowe, Darrell Conklin, Adam Pawson, Stuart Maudsley, Brigitte Troskie, Thomas Ott, Michael Millar, Gerald Lincoln, Robin Sellar, Bjarne Faurholm, Graeme Scobie, Rolf Kuestner, Ei Terasawa, and Arieh Katz
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9636–9641. Published online 2001 August 7. doi: 10.1073/pnas.141048498.
PMCID: PMC55504
From the Cover:
Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization
Concepción Gómez-Moutón, Jose Luis Abad, Emilia Mira, Rosa Ana Lacalle, Eduard Gallardo, Sonia Jiménez-Baranda, Isabel Illa, Antonio Bernad, Santos Mañes, and Carlos Martínez-A.
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9642–9647. Published online 2001 August 7. doi: 10.1073/pnas.171160298.
PMCID: PMC55505
The Sec6/8 complex in mammalian cells: Characterization of mammalian Sec3, subunit interactions, and expression of subunits in polarized cells
Hugo T. Matern, Charles Yeaman, W. James Nelson, and Richard H. Scheller
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9648–9653. Published online 2001 August 7. doi: 10.1073/pnas.171317898.
PMCID: PMC55506
Differential effects of p19Arf and p16Ink4a loss on senescence of murine bone marrow-derived preB cells and macrophages
David H. Randle, Frederique Zindy, Charles J. Sherr, and Martine F. Roussel
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9654–9659. Published online 2001 July 31. doi: 10.1073/pnas.171217498.
PMCID: PMC55507
The yeast mutant vps5Δ affected in the recycling of Golgi membrane proteins displays an enhanced vacuolar Mg2+/H+ exchange activity
Gilles Borrelly, Jean-Christophe Boyer, Brigitte Touraine, Wojciech Szponarski, Michèle Rambier, and Rémy Gibrat
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9660–9665. Published online 2001 August 7. doi: 10.1073/pnas.161215198.
PMCID: PMC55508
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
Hisashi Harada, Jens S. Andersen, Matthias Mann, Naohiro Terada, and Stanley J. Korsmeyer
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9666–9670. Published online 2001 August 7. doi: 10.1073/pnas.171301998.
PMCID: PMC55509
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53
Makoto Nagashima, Masayuki Shiseki, Koh Miura, Koichi Hagiwara, Steven P. Linke, Remy Pedeux, Xin W. Wang, Jun Yokota, Karl Riabowol, and Curtis C. Harris
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9671–9676. Published online 2001 July 31. doi: 10.1073/pnas.161151798.
PMCID: PMC55510
Developmental Biology
Sexual dimorphism among bovine embryos in their ability to make the transition to expanded blastocyst and in the expression of the signaling molecule IFN-τ
Melissa A. Larson, Koji Kimura, H. Michael Kubisch, and R. Michael Roberts
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9677–9682. Published online 2001 July 31. doi: 10.1073/pnas.171305398.
PMCID: PMC55511
Apaf-1 deficiency and neural tube closure defects are found in fog mice
Narimon Honarpour, Sandra L. Gilbert, Bruce T. Lahn, Xiaodong Wang, and Joachim Herz
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9683–9687. doi: 10.1073/pnas.171283198.
PMCID: PMC55512
Primary defects in the lens underlie complex anterior segment abnormalities of the Pax6 heterozygous eye
J. Martin Collinson, Jane C. Quinn, Malcolm A. Buchanan, Matthew H. Kaufman, Sarah E. Wedden, John D. West, and Robert E. Hill
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9688–9693. Published online 2001 July 31. doi: 10.1073/pnas.161144098.
PMCID: PMC55513
Functional analysis of the LACERATA gene of Arabidopsis provides evidence for different roles of fatty acid ω-hydroxylation in development
Kirsten Wellesen, Francis Durst, Franck Pinot, Irene Benveniste, Klaus Nettesheim, Ellen Wisman, Sabine Steiner-Lange, Heinz Saedler, and Alexander Yephremov
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9694–9699. Published online 2001 August 7. doi: 10.1073/pnas.171285998.
PMCID: PMC55514
Ecology
From the Cover:
Bat predation on nocturnally migrating birds
Carlos Ibáñez, Javier Juste, Juan L. García-Mudarra, and Pablo T. Agirre-Mendi
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9700–9702. Published online 2001 August 7. doi: 10.1073/pnas.171140598.
PMCID: PMC55515
Phase transition between disordered and ordered foraging in Pharaoh's ants
Madeleine Beekman, David J. T. Sumpter, and Francis L. W. Ratnieks
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9703–9706. Published online 2001 August 7. doi: 10.1073/pnas.161285298.
PMCID: PMC55516
Evolution
Evaluating hypotheses of basal animal phylogeny using complete sequences of large and small subunit rRNA
Mónica Medina, Allen G. Collins, Jeffrey D. Silberman, and Mitchell L. Sogin
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9707–9712. doi: 10.1073/pnas.171316998.
PMCID: PMC55517
Genetics
Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor
Darko Knutti, Dieter Kressler, and Anastasia Kralli
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9713–9718. Published online 2001 July 31. doi: 10.1073/pnas.171184698.
PMCID: PMC55518
SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway
K. L. Woodford-Richens, A. J. Rowan, P. Gorman, S. Halford, D. C. Bicknell, H. S. Wasan, R. R. Roylance, W. F. Bodmer, and I. P. M. Tomlinson
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9719–9723. Published online 2001 July 31. doi: 10.1073/pnas.171321498.
PMCID: PMC55519
Transgene analysis proves mRNA trans-splicing at the complex mod(mdg4) locus in Drosophila
Rainer Dorn, Gunter Reuter, and Andrea Loewendorf
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9724–9729. Published online 2001 August 7. doi: 10.1073/pnas.151268698.
PMCID: PMC55520
Essential role of Drosophila Hdac1 in homeotic gene silencing
Yuh-Long Chang, Yu-Huei Peng, I-Ching Pan, Der-Shan Sun, Balas King, and Der-Hwa Huang
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9730–9735. Published online 2001 August 7. doi: 10.1073/pnas.171325498.
PMCID: PMC55521
From the Cover:
A conserved RNA structure (thi box) is involved in regulation of thiamin biosynthetic gene expression in bacteria
Juan Miranda-Ríos, Margarito Navarro, and Mario Soberón
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9736–9741. Published online 2001 July 24. doi: 10.1073/pnas.161168098.
PMCID: PMC55522
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
Natasha J. Caplen, Susan Parrish, Farhad Imani, Andrew Fire, and Richard A. Morgan
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9742–9747. Published online 2001 July 31. doi: 10.1073/pnas.171251798.
PMCID: PMC55523
An Eulerian path approach to DNA fragment assembly
Pavel A. Pevzner, Haixu Tang, and Michael S. Waterman
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9748–9753. doi: 10.1073/pnas.171285098.
PMCID: PMC55524
Gene expression profiling of clear cell renal cell carcinoma: Gene identification and prognostic classification
Masayuki Takahashi, Daniel R. Rhodes, Kyle A. Furge, Hiro-omi Kanayama, Susumu Kagawa, Brian B. Haab, and Bin Tean Teh
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9754–9759. Published online 2001 August 7. doi: 10.1073/pnas.171209998.
PMCID: PMC55525
Interactions of Exo1p with components of MutLα in Saccharomyces cerevisiae
Phuoc T. Tran, Jeffrey A. Simon, and R. Michael Liskay
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9760–9765. Published online 2001 July 31. doi: 10.1073/pnas.161175998.
PMCID: PMC55526
Type I topoisomerase activity is required for proper chromosomal segregation in Escherichia coli
Qing Zhu, Pintip Pongpech, and Russell J. DiGate
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9766–9771. Published online 2001 August 7. doi: 10.1073/pnas.171579898.
PMCID: PMC55527
Immunology
Identification of a family of Fc receptor homologs with preferential B cell expression
Randall S. Davis, Yui-Hsi Wang, Hiromi Kubagawa, and Max D. Cooper
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9772–9777. Published online 2001 August 7. doi: 10.1073/pnas.171308498.
PMCID: PMC55528
Molecular cloning of Porimin, a novel cell surface receptor mediating oncotic cell death
Fengrong Ma, Chonghui Zhang, K. V. S. Prasad, Gordon J. Freeman, and Stuart F. Schlossman
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9778–9783. Published online 2001 July 31. doi: 10.1073/pnas.171322898.
PMCID: PMC55529
Medical Sciences
Nephrocystin interacts with Pyk2, p130Cas, and tensin and triggers phosphorylation of Pyk2
Thomas Benzing, Peter Gerke, Katja Höpker, Friedhelm Hildebrandt, Emily Kim, and Gerd Walz
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9784–9789. Published online 2001 August 7. doi: 10.1073/pnas.171269898.
PMCID: PMC55530
UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53
Weidong Jiang, Honnavara N. Ananthaswamy, H. Konrad Muller, Allal Ouhtit, Svetlana Bolshakov, Stephen E. Ullrich, Adel K. El-Naggar, and Margaret L. Kripke
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9790–9795. Published online 2001 July 31. doi: 10.1073/pnas.171066498.
PMCID: PMC55531
HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells
Ian E. Krop, Dennis Sgroi, Dale A. Porter, Kathryn L. Lunetta, Rebbecca LeVangie, Pankaj Seth, Carolyn M. Kaelin, Esther Rhei, Marcus Bosenberg, Stuart Schnitt, Jeffrey R. Marks, Zrinka Pagon, Drazen Belina, Jasminka Razumovic, and Kornelia Polyak
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9796–9801. Published online 2001 July 31. doi: 10.1073/pnas.171138398.
PMCID: PMC55532
Near-precise interchromosomal recombination and functional DNA topoisomerase II cleavage sites at MLL and AF-4 genomic breakpoints in treatment-related acute lymphoblastic leukemia with t(4;11) translocation
Brian D. Lovett, Luca Lo Nigro, Eric F. Rappaport, Ian A. Blair, Neil Osheroff, Naiyu Zheng, Maureen D. Megonigal, Wendy Reed Williams, Peter C. Nowell, and Carolyn A. Felix
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9802–9807. Published online 2001 August 7. doi: 10.1073/pnas.171309898.
PMCID: PMC55533
Treatment of spinal muscular atrophy by sodium butyrate
Jan-Gowth Chang, Hsiu-Mei Hsieh-Li, Yuh-Jyh Jong, Nancy M. Wang, Chang-Hai Tsai, and Hung Li
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9808–9813. doi: 10.1073/pnas.171105098.
PMCID: PMC55534
Spatial–temporal imaging of bacterial infection and antibiotic response in intact animals
Ming Zhao, Meng Yang, Eugene Baranov, Xiaoen Wang, Sheldon Penman, A. R. Moossa, and Robert M. Hoffman
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9814–9818. Published online 2001 July 31. doi: 10.1073/pnas.161275798.
PMCID: PMC55535
Antisense DNAs as multisite genomic modulators identified by DNA microarray
Yee Sook Cho, Meyoung-Kon Kim, Chris Cheadle, Catherine Neary, Kevin G. Becker, and Yoon S. Cho-Chung
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9819–9823. Published online 2001 July 31. doi: 10.1073/pnas.171314398.
PMCID: PMC55536
An immune response manifested by the common occurrence of annexins I and II autoantibodies and high circulating levels of IL-6 in lung cancer
Franck M. Brichory, David E. Misek, Anne-Marie Yim, Melissa C. Krause, Thomas J. Giordano, David G. Beer, and Samir M. Hanash
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9824–9829. doi: 10.1073/pnas.171320598.
PMCID: PMC55537
Heart regeneration in adult MRL mice
John M. Leferovich, Khamilia Bedelbaeva, Stefan Samulewicz, Xiang-Ming Zhang, Donna Zwas, Edward B. Lankford, and Ellen Heber-Katz
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9830–9835. Published online 2001 August 7. doi: 10.1073/pnas.181329398.
PMCID: PMC55538
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease
Carsten Korth, Barnaby C. H. May, Fred E. Cohen, and Stanley B. Prusiner
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9836–9841. doi: 10.1073/pnas.161274798.
PMCID: PMC55539
A new recommended dietary allowance of vitamin C for healthy young women
Mark Levine, Yaohui Wang, Sebastian J. Padayatty, and Jason Morrow
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9842–9846. doi: 10.1073/pnas.171318198.
PMCID: PMC55540
Hepatitis C virus replication is directly inhibited by IFN-α in a full-length binary expression system
Raymond T. Chung, Wenping He, Afroz Saquib, Ana M. Contreras, Ramnik J. Xavier, Ashish Chawla, Timothy C. Wang, and Emmett V. Schmidt
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9847–9852. Published online 2001 August 7. doi: 10.1073/pnas.171319698.
PMCID: PMC55541
Microbiology
DNA/DNA hybridization to microarrays reveals gene-specific differences between closely related microbial genomes
A. E. Murray, D. Lies, G. Li, K. Nealson, J. Zhou, and J. M. Tiedje
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9853–9858. Published online 2001 August 7. doi: 10.1073/pnas.171178898.
PMCID: PMC55542
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion
Luis González-Reyes, M. Begoña Ruiz-Argüello, Blanca García-Barreno, Leslie Calder, Juan A. López, Juan P. Albar, John J. Skehel, Don C. Wiley, and José A. Melero
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9859–9864. Published online 2001 August 7. doi: 10.1073/pnas.151098198.
PMCID: PMC55543
The evolution of methicillin resistance in Staphylococcus aureus: Similarity of genetic backgrounds in historically early methicillin-susceptible and -resistant isolates and contemporary epidemic clones
M. Inês Crisóstomo, Henrik Westh, Alexander Tomasz, Marilyn Chung, Duarte C. Oliveira, and Hermínia de Lencastre
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9865–9870. Published online 2001 July 31. doi: 10.1073/pnas.161272898.
PMCID: PMC55544
Polar targeting of Shigella virulence factor IcsA in Enterobacteriacae and Vibrio
Macarthur Charles, Marisa Pérez, Jessica H. Kobil, and Marcia B. Goldberg
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9871–9876. Published online 2001 July 31. doi: 10.1073/pnas.171310498.
PMCID: PMC55545
From the Cover:
Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021
Delphine Capela, Frédérique Barloy-Hubler, Jérôme Gouzy, Gordana Bothe, Frédéric Ampe, Jacques Batut, Pierre Boistard, Anke Becker, Marc Boutry, Edouard Cadieu, Stéphane Dréano, Stéphanie Gloux, Thérèse Godrie, André Goffeau, Daniel Kahn, Ernö Kiss, Valérie Lelaure, David Masuy, Thomas Pohl, Daniel Portetelle, Alfred Pühler, Bénédicte Purnelle, Ulf Ramsperger, Clotilde Renard, Patricia Thébault, Micheline Vandenbol, Stefan Weidner, and Francis Galibert
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9877–9882. Published online 2001 July 31. doi: 10.1073/pnas.161294398.
PMCID: PMC55546
From the Cover:
Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid
Melanie J. Barnett, Robert F. Fisher, Ted Jones, Caridad Komp, A. Pia Abola, Frédérique Barloy-Hubler, Leah Bowser, Delphine Capela, Francis Galibert, Jérôme Gouzy, Mani Gurjal, Andrea Hong, Lucas Huizar, Richard W. Hyman, Daniel Kahn, Michael L. Kahn, Sue Kalman, David H. Keating, Curtis Palm, Melicent C. Peck, Raymond Surzycki, Derek H. Wells, Kuo-Chen Yeh, Ronald W. Davis, Nancy A. Federspiel, and Sharon R. Long
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9883–9888. Published online 2001 July 31. doi: 10.1073/pnas.161294798.
PMCID: PMC55547
From the Cover:
The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing endosymbiont Sinorhizobium meliloti
Turlough M. Finan, Stefan Weidner, Kim Wong, Jens Buhrmester, Patrick Chain, Frank J. Vorhölter, Ismael Hernandez-Lucas, Anke Becker, Alison Cowie, Jérôme Gouzy, Brian Golding, and Alfred Pühler
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9889–9894. Published online 2001 July 31. doi: 10.1073/pnas.161294698.
PMCID: PMC55548
Exploring the transcriptome of the malaria sporozoite stage
Stefan H. I. Kappe, Malcolm J. Gardner, Stuart M. Brown, Jessica Ross, Kai Matuschewski, Jose M. Ribeiro, John H. Adams, John Quackenbush, Jennifer Cho, Daniel J. Carucci, Stephen L. Hoffman, and Victor Nussenzweig
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9895–9900. Published online 2001 August 7. doi: 10.1073/pnas.171185198.
PMCID: PMC55549
Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates
Gregory St. John, Nathan Brot, Jia Ruan, Hediye Erdjument-Bromage, Paul Tempst, Herbert Weissbach, and Carl Nathan
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9901–9906. Published online 2001 July 31. doi: 10.1073/pnas.161295398.
PMCID: PMC55550
Neurobiology
Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized
Youlin Ruan, Laurence Tecott, Ming-Ming Jiang, Lily Yeh Jan, and Yuh Nung Jan
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9907–9912. Published online 2001 July 31. doi: 10.1073/pnas.171321098.
PMCID: PMC55551
Brain glucose utilization in mice with a targeted mutation in the thyroid hormone α or β receptor gene
Yoshiaki Itoh, Takanori Esaki, Masahiro Kaneshige, Hideyo Suzuki, Michelle Cook, Louis Sokoloff, Sheue-Yann Cheng, and Jacques Nunez
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9913–9918. Published online 2001 July 31. doi: 10.1073/pnas.171319498.
PMCID: PMC55552
A role for muscarinic excitation: Control of specific singing behavior by activation of the adenylate cyclase pathway in the brain of grasshoppers
Ralf Heinrich, Beate Wenzel, and Norbert Elsner
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9919–9923. Published online 2001 July 3. doi: 10.1073/pnas.151131998.
PMCID: PMC55553
Neural agrin controls acetylcholine receptor stability in skeletal muscle fibers
Gabriela Bezakova, Inger Rabben, Iren Sefland, Guido Fumagalli, and Terje Lømo
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9924–9929. Published online 2001 August 7. doi: 10.1073/pnas.171539698.
PMCID: PMC55554
A neurohistochemical blueprint for pain-induced loss of appetite
Amy Malick, Moshe Jakubowski, Joel K. Elmquist, Clifford B. Saper, and Rami Burstein
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9930–9935. doi: 10.1073/pnas.171616898.
PMCID: PMC55555
Trypanosoma cruzi trans-sialidase: A potent and specific survival factor for human Schwann cells by means of phosphatidylinositol 3-kinase/Akt signaling
Marina V. Chuenkova, Frank B. Furnari, Webster K. Cavenee, and Miercio A. Pereira
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9936–9941. Published online 2001 July 31. doi: 10.1073/pnas.161298398.
PMCID: PMC55556
Subretinal transplantation of genetically modified human cell lines attenuates loss of visual function in dystrophic rats
Raymond D. Lund, Peter Adamson, Yves Sauvé, David J. Keegan, Sergej V. Girman, Shaomei Wang, Helen Winton, Naheed Kanuga, Anthony S. L. Kwan, Laurence Beauchène, Anne Zerbib, Len Hetherington, Pierre-Olivier Couraud, Peter Coffey, and John Greenwood
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9942–9947. doi: 10.1073/pnas.171266298.
PMCID: PMC55557
Role of guanylate cyclase-activating proteins (GCAPs) in setting the flash sensitivity of rod photoreceptors
Ana Mendez, Marie E. Burns, Izabela Sokal, Alexander M. Dizhoor, Wolfgang Baehr, Krzysztof Palczewski, Denis A. Baylor, and Jeannie Chen
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9948–9953. Published online 2001 August 7. doi: 10.1073/pnas.171308998.
PMCID: PMC55558
Role of glutamate δ-2 receptors in activity-dependent competition between heterologous afferent fibers
Laura Morando, Roberta Cesa, Roberta Rasetti, Robin Harvey, and Piergiorgio Strata
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9954–9959. Published online 2001 August 7. doi: 10.1073/pnas.171098398.
PMCID: PMC55559
Receptor subtype-specific pronociceptive and analgesic actions of galanin in the spinal cord: Selective actions via GalR1 and GalR2 receptors
Hong-Xiang Liu, Pablo Brumovsky, Ralf Schmidt, William Brown, Kemal Payza, Lejla Hodzic, Chantevy Pou, Claude Godbout, and Tomas Hökfelt
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9960–9964. Published online 2001 July 31. doi: 10.1073/pnas.161293598.
PMCID: PMC55560
Arousal effect of orexin A depends on activation of the histaminergic system
Zhi-Li Huang, Wei-Min Qu, Wei-Dong Li, Takatoshi Mochizuki, Naomi Eguchi, Takeshi Watanabe, Yoshihiro Urade, and Osamu Hayaishi
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9965–9970. Published online 2001 August 7. doi: 10.1073/pnas.181330998.
PMCID: PMC55561
Identification of peptides from brain and pituitary of Cpefat/Cpefat mice
Fa-Yun Che, Lin Yan, Hong Li, Nino Mzhavia, Lakshmi A. Devi, and Lloyd D. Fricker
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9971–9976. Published online 2001 July 31. doi: 10.1073/pnas.161542198.
PMCID: PMC55562
Pharmacology
Heart-targeted overexpression of caspase3 in mice increases infarct size and depresses cardiac function
Gianluigi Condorelli, Roberta Roncarati, John Ross, Jr., Angela Pisani, Giorgio Stassi, Matilde Todaro, Stephen Trocha, Alessandra Drusco, Yusu Gu, Matteo A. Russo, Giacomo Frati, Steven P. Jones, David J. Lefer, Claudio Napoli, and Carlo M. Croce
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9977–9982. Published online 2001 August 7. doi: 10.1073/pnas.161120198.
PMCID: PMC55563
Physiology
Mediation of tubuloglomerular feedback by adenosine: Evidence from mice lacking adenosine 1 receptors
Daqing Sun, Linda C. Samuelson, Tianxin Yang, Yuning Huang, Alex Paliege, Thom Saunders, Josie Briggs, and Jurgen Schnermann
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9983–9988. doi: 10.1073/pnas.171317998.
PMCID: PMC55564
Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in mice
Y. Liao, K. H. Day, D. N. Damon, and B. R. Duling
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9989–9994. Published online 2001 July 31. doi: 10.1073/pnas.171305298.
PMCID: PMC55565
Plant Biology
Functional activity and role of cation-efflux family members in Ni hyperaccumulation in Thlaspi goesingense
Michael W. Persans, Ken Nieman, and David E. Salt
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9995–10000. Published online 2001 July 31. doi: 10.1073/pnas.171039798.
PMCID: PMC55566
Enhanced synthesis of choline and glycine betaine in transgenic tobacco plants that overexpress phosphoethanolamine N-methyltransferase
Scott D. McNeil, Michael L. Nuccio, Michael J. Ziemak, and Andrew D. Hanson
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10001–10005. Published online 2001 July 31. doi: 10.1073/pnas.171228998.
PMCID: PMC55567
Psychology
Crossmodal binding of fear in voice and face
R. J. Dolan, J. S. Morris, and B. de Gelder
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10006–10010. Published online 2001 August 7. doi: 10.1073/pnas.171288598.
PMCID: PMC55568
Social Sciences
Anthropology
A cranium for the earliest Europeans: Phylogenetic position of the hominid from Ceprano, Italy
G. Manzi, F. Mallegni, and A. Ascenzi
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10011–10016. doi: 10.1073/pnas.151259998.
PMCID: PMC55569
Old World sources of the first New World human inhabitants: A comparative craniofacial view
C. Loring Brace, A. Russell Nelson, Noriko Seguchi, Hiroaki Oe, Leslie Sering, Pan Qifeng, Li Yongyi, and Dashtseveg Tumen
Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10017–10022. Published online 2001 July 31. doi: 10.1073/pnas.171305898.
PMCID: PMC55570
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