| | This journal provides immediate access to some articles. Commentaries Do mRNAs act as direct sensors of small molecules to control
their expression? Gary D. Stormo and Yongmei Ji Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9465–9467. doi: 10.1073/pnas.181334498.PMCID: PMC55472 Multidisciplinary dissection of behavioral arousal: The role
of muscarinic acetylcholine stimulation in grasshopper stridulatory
behavior Moira J. van Staaden and Robert Huber Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9468–9470. doi: 10.1073/pnas.181341098.PMCID: PMC55473 Flotillas of lipid rafts fore and aft Lynda M. Pierini and Frederick R. Maxfield Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9471–9473. doi: 10.1073/pnas.181353098.PMCID: PMC55474 Following the trace of elusive amines Richard T. Premont, Raul R. Gainetdinov, and Marc G. Caron Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9474–9475. doi: 10.1073/pnas.181356198.PMCID: PMC55475 Physical Sciences Applied Mathematics An Eulerian path approach to DNA fragment assembly Pavel A. Pevzner, Haixu Tang, and Michael S. Waterman Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9748–9753. doi: 10.1073/pnas.171285098.PMCID: PMC55524 Astronomy Theoretical emission line ratios for [Fe III] and [Fe VII]
applicable to the optical and infrared spectra of gaseous nebulae Francis P. Keenan, Lawrence H. Aller, Robert S. I. Ryans, and Siek Hyung Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9476–9477. Published online 2001 August 7. doi: 10.1073/pnas.151263098.PMCID: PMC55476 Chemistry Interchain hydrogen-bonding interactions may facilitate
translocation of K+ ions across the potassium channel
selectivity filter, as suggested by synthetic modeling chemistry Juan C. Mareque Rivas, Harald Schwalbe, and Stephen J. Lippard Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9478–9483. doi: 10.1073/pnas.161257798.PMCID: PMC55477 Geophysics Aggregate sound velocities and acoustic Grüneisen parameter
of iron up to 300 GPa and 1,200 K L. S. Dubrovinsky, N. A. Dubrovinskaia, and T. Le Bihan Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9484–9489. doi: 10.1073/pnas.161583398.PMCID: PMC55478 Physics Quantum optical implementation of Grover's algorithm Marlan O. Scully and M. S. Zubairy Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9490–9493. doi: 10.1073/pnas.171317798.PMCID: PMC55479 Biological Sciences Biochemistry Interchain hydrogen-bonding interactions may facilitate
translocation of K+ ions across the potassium channel
selectivity filter, as suggested by synthetic modeling chemistry Juan C. Mareque Rivas, Harald Schwalbe, and Stephen J. Lippard Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9478–9483. doi: 10.1073/pnas.161257798.PMCID: PMC55477 Formation of a selenium-substituted rhodanese by reaction with
selenite and glutathione: Possible role of a protein perselenide in
a selenium delivery system Yuki Ogasawara, Gerard Lacourciere, and Thressa C. Stadtman Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9494–9498. Published online 2001 August 7. doi: 10.1073/pnas.171320998.PMCID: PMC55480 Characterization of an adapter subunit to a phosphatidylinositol
(3)P 3-phosphatase: Identification of a myotubularin-related protein lacking catalytic activity H. H. Nandurkar, K. K. Caldwell, J. C. Whisstock, M. J. Layton, E. A. Gaudet, F. A. Norris, P. W. Majerus, and C. A. Mitchell Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9499–9504. doi: 10.1073/pnas.171306098.PMCID: PMC55481 Mitochondria play no roles in Mn(II)-induced apoptosis in
HeLa cells Hammou Oubrahim, Earl R. Stadtman, and P. Boon Chock Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9505–9510. Published online 2001 August 7. doi: 10.1073/pnas.181319898.PMCID: PMC55482 A soluble class II cytokine receptor, IL-22RA2, is a naturally
occurring IL-22 antagonist Wenfeng Xu, Scott R. Presnell, Julia Parrish-Novak, Wayne Kindsvogel, Steve Jaspers, Zhi Chen, Stacey R. Dillon, Zeren Gao, Teresa Gilbert, Karen Madden, Stacy Schlutsmeyer, Lena Yao, Theodore E. Whitmore, Yasmin Chandrasekher, Francis J. Grant, Mark Maurer, Laura Jelinek, Harold Storey, Ty Brender, Angie Hammond, Stavros Topouzis, Christopher H. Clegg, and Donald C. Foster Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9511–9516. Published online 2001 July 31. doi: 10.1073/pnas.171303198.PMCID: PMC55483 Propagating conformational changes over long (and short)
distances in proteins Edward W. Yu and Daniel E. Koshland, Jr. Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9517–9520. doi: 10.1073/pnas.161239298.PMCID: PMC55484 Mapping the interactions between flavodoxin and its physiological
partners flavodoxin reductase and cobalamin-dependent
methionine synthase Diane A. Hall, Craig W. Vander Kooi, Chad N. Stasik, Shawn Y. Stevens, Erik R. P. Zuiderweg, and Rowena G. Matthews Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9521–9526. Published online 2001 August 7. doi: 10.1073/pnas.171168898.PMCID: PMC55485 The active site dynamics of 4-chlorobenzoyl-CoA dehalogenase Edmond Y. Lau and Thomas C. Bruice Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9527–9532. Published online 2001 August 7. doi: 10.1073/pnas.161282698.PMCID: PMC55486 Three-dimensional structure of a mammalian thioredoxin reductase:
Implications for mechanism and evolution of a selenocysteine-dependent enzyme Tatyana Sandalova, Liangwei Zhong, Ylva Lindqvist, Arne Holmgren, and Gunter Schneider Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9533–9538. Published online 2001 July 31. doi: 10.1073/pnas.171178698.PMCID: PMC55487 Mechanism of transfer of NO from extracellular
S-nitrosothiols into the cytosol by cell-surface protein disulfide isomerase Niroshan Ramachandran, Paul Root, Xing-Mai Jiang, Phillip J. Hogg, and Bulent Mutus Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9539–9544. Published online 2001 August 7. doi: 10.1073/pnas.171180998.PMCID: PMC55488 Crystal structure of the dimeric extracellular domain of human
carbonic anhydrase XII, a bitopic membrane protein overexpressed
in certain cancer tumor cells Douglas A. Whittington, Abdul Waheed, Barbara Ulmasov, Gul N. Shah, Jeffrey H. Grubb, William S. Sly, and David W. Christianson Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9545–9550. Published online 2001 August 7. doi: 10.1073/pnas.161301298.PMCID: PMC55489 DsbC activation by the N-terminal domain of DsbD David Goldstone, Peter W. Haebel, Federico Katzen, Martin W. Bader, James C. A. Bardwell, Jon Beckwith, and Peter Metcalf Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9551–9556. Published online 2001 August 7. doi: 10.1073/pnas.171315498.PMCID: PMC55490 Structure of the gene 2.5 protein, a single-stranded DNA binding
protein encoded by bacteriophage T7 Thomas Hollis, James M. Stattel, Dane S. Walther, Charles C. Richardson, and Tom Ellenberger Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9557–9562. Published online 2001 July 31. doi: 10.1073/pnas.171317698.PMCID: PMC55491 A Drosophila PIAS homologue negatively
regulates stat92E Aurel Betz, Nina Lampen, Sebastian Martinek, Michael W. Young, and James E. Darnell, Jr. Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9563–9568. doi: 10.1073/pnas.171302098.PMCID: PMC55492 Mechanism of termination of DNA replication of
Escherichia coli involves helicase–contrahelicase
interaction Sashidhar Mulugu, Aardra Potnis, Shamsuzzaman, Jeffery Taylor, Ken Alexander, and Deepak Bastia Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9569–9574. Published online 2001 August 7. doi: 10.1073/pnas.171065898.PMCID: PMC55493 Cross talk among calcineurin, Sp1/Sp3, and NFAT in control
of p21WAF1/CIP1 expression in keratinocyte differentiation Maria Paola Santini, Claudio Talora, Toshihiko Seki, Loretta Bolgan, and G. Paolo Dotto Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9575–9580. Published online 2001 August 7. doi: 10.1073/pnas.161299698.PMCID: PMC55494 Kinetic trapping of DNA by transcription factor IIIB Timothy E. Cloutier, Monett D. Librizzi, A. K. M. M. Mollah, Michael Brenowitz, and Ian M. Willis Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9581–9586. Published online 2001 July 31. doi: 10.1073/pnas.161292298.PMCID: PMC55495 BRCA1 mediates ligand-independent transcriptional repression of
the estrogen receptor Lei Zheng, Lois A. Annab, Cynthia A. Afshari, Wen-Hwa Lee, and Thomas G. Boyer Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9587–9592. Published online 2001 August 7. doi: 10.1073/pnas.171174298.PMCID: PMC55496 A metallothionein containing a zinc finger within a
four-metal cluster protects a bacterium from zinc toxicity Claudia A. Blindauer, Mark D. Harrison, John A. Parkinson, Andrea K. Robinson, Jennifer S. Cavet, Nigel J. Robinson, and Peter J. Sadler Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9593–9598. Published online 2001 August 7. doi: 10.1073/pnas.171120098.PMCID: PMC55497 Human hepatitis C virus NS5A protein alters intracellular calcium
levels, induces oxidative stress, and activates STAT-3
and NF-κB Guozhong Gong, Gulam Waris, Rasheeda Tanveer, and Aleem Siddiqui Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9599–9604. Published online 2001 July 31. doi: 10.1073/pnas.171311298.PMCID: PMC55498 Activation and autoregulation of DNA-PK from structured
single-stranded DNA and coding end hairpins Sébastien Soubeyrand, Heather Torrance, Ward Giffin, Wenrong Gong, Caroline Schild-Poulter, and Robert J. G. Haché Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9605–9610. Published online 2001 July 31. doi: 10.1073/pnas.171211398.PMCID: PMC55499 Ubiquitination and degradation of Syk and ZAP-70 protein tyrosine
kinases in human NK cells upon CD16 engagement Rossella Paolini, Rosa Molfetta, Mario Piccoli, Luigi Frati, and Angela Santoni Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9611–9616. Published online 2001 August 7. doi: 10.1073/pnas.161298098.PMCID: PMC55500 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Periodic perturbations in Shaker K +
channel gating kinetics by deletions in the S3–S4 linker Carlos Gonzalez, Eduardo Rosenman, Francisco Bezanilla, Osvaldo Alvarez, and Ramon Latorre Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9617–9623. Published online 2001 August 7. doi: 10.1073/pnas.171306298.PMCID: PMC55501 Highly selective water channel activity measured by voltage
clamp: Analysis of planar lipid bilayers reconstituted with
purified AqpZ Peter Pohl, Sapar M. Saparov, Mario J. Borgnia, and Peter Agre Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9624–9629. Published online 2001 August 7. doi: 10.1073/pnas.161299398.PMCID: PMC55502 Cell Biology HIF-1α binding to VHL is regulated by stimulus-sensitive
proline hydroxylation Fang Yu, Sarah B. White, Quan Zhao, and Frank S. Lee Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9630–9635. doi: 10.1073/pnas.181341498.PMCID: PMC55503 A novel mammalian receptor for the evolutionarily conserved type
II GnRH Robert Millar, Steven Lowe, Darrell Conklin, Adam Pawson, Stuart Maudsley, Brigitte Troskie, Thomas Ott, Michael Millar, Gerald Lincoln, Robin Sellar, Bjarne Faurholm, Graeme Scobie, Rolf Kuestner, Ei Terasawa, and Arieh Katz Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9636–9641. Published online 2001 August 7. doi: 10.1073/pnas.141048498.PMCID: PMC55504 From the Cover: Segregation of leading-edge and uropod components into specific
lipid rafts during T cell polarization Concepción Gómez-Moutón, Jose Luis Abad, Emilia Mira, Rosa Ana Lacalle, Eduard Gallardo, Sonia Jiménez-Baranda, Isabel Illa, Antonio Bernad, Santos Mañes, and Carlos Martínez-A. Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9642–9647. Published online 2001 August 7. doi: 10.1073/pnas.171160298.PMCID: PMC55505 INAUGURAL ARTICLE by a Recently Elected Academy Member: The Sec6/8 complex in mammalian cells: Characterization of
mammalian Sec3, subunit interactions, and expression of
subunits in polarized cells Hugo T. Matern, Charles Yeaman, W. James Nelson, and Richard H. Scheller Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9648–9653. Published online 2001 August 7. doi: 10.1073/pnas.171317898.PMCID: PMC55506 Differential effects of p19Arf and
p16Ink4a loss on senescence of murine bone
marrow-derived preB cells and macrophages David H. Randle, Frederique Zindy, Charles J. Sherr, and Martine F. Roussel Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9654–9659. Published online 2001 July 31. doi: 10.1073/pnas.171217498.PMCID: PMC55507 The yeast mutant vps5Δ affected in the recycling
of Golgi membrane proteins displays an enhanced vacuolar
Mg2+/H+ exchange activity Gilles Borrelly, Jean-Christophe Boyer, Brigitte Touraine, Wojciech Szponarski, Michèle Rambier, and Rémy Gibrat Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9660–9665. Published online 2001 August 7. doi: 10.1073/pnas.161215198.PMCID: PMC55508 p70S6 kinase signals cell survival as well as growth,
inactivating the pro-apoptotic molecule BAD Hisashi Harada, Jens S. Andersen, Matthias Mann, Naohiro Terada, and Stanley J. Korsmeyer Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9666–9670. Published online 2001 August 7. doi: 10.1073/pnas.171301998.PMCID: PMC55509 DNA damage-inducible gene p33ING2 negatively
regulates cell proliferation through acetylation of p53 Makoto Nagashima, Masayuki Shiseki, Koh Miura, Koichi Hagiwara, Steven P. Linke, Remy Pedeux, Xin W. Wang, Jun Yokota, Karl Riabowol, and Curtis C. Harris Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9671–9676. Published online 2001 July 31. doi: 10.1073/pnas.161151798.PMCID: PMC55510 Developmental Biology Sexual dimorphism among bovine embryos in their ability to make
the transition to expanded blastocyst and in the expression of
the signaling molecule IFN-τ Melissa A. Larson, Koji Kimura, H. Michael Kubisch, and R. Michael Roberts Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9677–9682. Published online 2001 July 31. doi: 10.1073/pnas.171305398.PMCID: PMC55511 Apaf-1 deficiency and neural tube closure defects
are found in fog mice Narimon Honarpour, Sandra L. Gilbert, Bruce T. Lahn, Xiaodong Wang, and Joachim Herz Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9683–9687. doi: 10.1073/pnas.171283198.PMCID: PMC55512 Primary defects in the lens underlie complex anterior segment
abnormalities of the Pax6 heterozygous eye J. Martin Collinson, Jane C. Quinn, Malcolm A. Buchanan, Matthew H. Kaufman, Sarah E. Wedden, John D. West, and Robert E. Hill Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9688–9693. Published online 2001 July 31. doi: 10.1073/pnas.161144098.PMCID: PMC55513 Functional analysis of the LACERATA gene of
Arabidopsis provides evidence for different roles of
fatty acid ω-hydroxylation in development Kirsten Wellesen, Francis Durst, Franck Pinot, Irene Benveniste, Klaus Nettesheim, Ellen Wisman, Sabine Steiner-Lange, Heinz Saedler, and Alexander Yephremov Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9694–9699. Published online 2001 August 7. doi: 10.1073/pnas.171285998.PMCID: PMC55514 Ecology From the Cover: Bat predation on nocturnally migrating birds Carlos Ibáñez, Javier Juste, Juan L. García-Mudarra, and Pablo T. Agirre-Mendi Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9700–9702. Published online 2001 August 7. doi: 10.1073/pnas.171140598.PMCID: PMC55515 Phase transition between disordered and ordered foraging in
Pharaoh's ants Madeleine Beekman, David J. T. Sumpter, and Francis L. W. Ratnieks Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9703–9706. Published online 2001 August 7. doi: 10.1073/pnas.161285298.PMCID: PMC55516 Evolution Evaluating hypotheses of basal animal phylogeny using complete
sequences of large and small subunit rRNA Mónica Medina, Allen G. Collins, Jeffrey D. Silberman, and Mitchell L. Sogin Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9707–9712. doi: 10.1073/pnas.171316998.PMCID: PMC55517 Genetics Regulation of the transcriptional coactivator PGC-1 via
MAPK-sensitive interaction with a repressor Darko Knutti, Dieter Kressler, and Anastasia Kralli Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9713–9718. Published online 2001 July 31. doi: 10.1073/pnas.171184698.PMCID: PMC55518 SMAD4 mutations in colorectal cancer probably occur before
chromosomal instability, but after divergence of the microsatellite
instability pathway K. L. Woodford-Richens, A. J. Rowan, P. Gorman, S. Halford, D. C. Bicknell, H. S. Wasan, R. R. Roylance, W. F. Bodmer, and I. P. M. Tomlinson Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9719–9723. Published online 2001 July 31. doi: 10.1073/pnas.171321498.PMCID: PMC55519 Transgene analysis proves mRNA trans-splicing at the complex
mod(mdg4) locus in Drosophila Rainer Dorn, Gunter Reuter, and Andrea Loewendorf Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9724–9729. Published online 2001 August 7. doi: 10.1073/pnas.151268698.PMCID: PMC55520 Essential role of Drosophila Hdac1 in homeotic
gene silencing Yuh-Long Chang, Yu-Huei Peng, I-Ching Pan, Der-Shan Sun, Balas King, and Der-Hwa Huang Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9730–9735. Published online 2001 August 7. doi: 10.1073/pnas.171325498.PMCID: PMC55521 From the Cover: A conserved RNA structure (thi box) is involved in
regulation of thiamin biosynthetic gene expression in bacteria Juan Miranda-Ríos, Margarito Navarro, and Mario Soberón Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9736–9741. Published online 2001 July 24. doi: 10.1073/pnas.161168098.PMCID: PMC55522 Specific inhibition of gene expression by small double-stranded
RNAs in invertebrate and vertebrate systems Natasha J. Caplen, Susan Parrish, Farhad Imani, Andrew Fire, and Richard A. Morgan Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9742–9747. Published online 2001 July 31. doi: 10.1073/pnas.171251798.PMCID: PMC55523 An Eulerian path approach to DNA fragment assembly Pavel A. Pevzner, Haixu Tang, and Michael S. Waterman Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9748–9753. doi: 10.1073/pnas.171285098.PMCID: PMC55524 Gene expression profiling of clear cell renal cell carcinoma:
Gene identification and prognostic classification Masayuki Takahashi, Daniel R. Rhodes, Kyle A. Furge, Hiro-omi Kanayama, Susumu Kagawa, Brian B. Haab, and Bin Tean Teh Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9754–9759. Published online 2001 August 7. doi: 10.1073/pnas.171209998.PMCID: PMC55525 Interactions of Exo1p with components of MutLα in
Saccharomyces cerevisiae Phuoc T. Tran, Jeffrey A. Simon, and R. Michael Liskay Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9760–9765. Published online 2001 July 31. doi: 10.1073/pnas.161175998.PMCID: PMC55526 Type I topoisomerase activity is required for proper chromosomal
segregation in Escherichia coli Qing Zhu, Pintip Pongpech, and Russell J. DiGate Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9766–9771. Published online 2001 August 7. doi: 10.1073/pnas.171579898.PMCID: PMC55527 Immunology Identification of a family of Fc receptor homologs with
preferential B cell expression Randall S. Davis, Yui-Hsi Wang, Hiromi Kubagawa, and Max D. Cooper Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9772–9777. Published online 2001 August 7. doi: 10.1073/pnas.171308498.PMCID: PMC55528 Molecular cloning of Porimin, a novel cell surface receptor
mediating oncotic cell death Fengrong Ma, Chonghui Zhang, K. V. S. Prasad, Gordon J. Freeman, and Stuart F. Schlossman Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9778–9783. Published online 2001 July 31. doi: 10.1073/pnas.171322898.PMCID: PMC55529 Medical Sciences Nephrocystin interacts with Pyk2, p130Cas, and tensin
and triggers phosphorylation of Pyk2 Thomas Benzing, Peter Gerke, Katja Höpker, Friedhelm Hildebrandt, Emily Kim, and Gerd Walz Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9784–9789. Published online 2001 August 7. doi: 10.1073/pnas.171269898.PMCID: PMC55530 UV irradiation augments lymphoid malignancies in mice with one
functional copy of wild-type p53 Weidong Jiang, Honnavara N. Ananthaswamy, H. Konrad Muller, Allal Ouhtit, Svetlana Bolshakov, Stephen E. Ullrich, Adel K. El-Naggar, and Margaret L. Kripke Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9790–9795. Published online 2001 July 31. doi: 10.1073/pnas.171066498.PMCID: PMC55531 HIN-1, a putative cytokine highly expressed in normal but not
cancerous mammary epithelial cells Ian E. Krop, Dennis Sgroi, Dale A. Porter, Kathryn L. Lunetta, Rebbecca LeVangie, Pankaj Seth, Carolyn M. Kaelin, Esther Rhei, Marcus Bosenberg, Stuart Schnitt, Jeffrey R. Marks, Zrinka Pagon, Drazen Belina, Jasminka Razumovic, and Kornelia Polyak Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9796–9801. Published online 2001 July 31. doi: 10.1073/pnas.171138398.PMCID: PMC55532 Near-precise interchromosomal recombination and functional DNA
topoisomerase II cleavage sites at MLL and
AF-4 genomic breakpoints in treatment-related acute
lymphoblastic leukemia with t(4;11) translocation Brian D. Lovett, Luca Lo Nigro, Eric F. Rappaport, Ian A. Blair, Neil Osheroff, Naiyu Zheng, Maureen D. Megonigal, Wendy Reed Williams, Peter C. Nowell, and Carolyn A. Felix Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9802–9807. Published online 2001 August 7. doi: 10.1073/pnas.171309898.PMCID: PMC55533 Treatment of spinal muscular atrophy by sodium butyrate Jan-Gowth Chang, Hsiu-Mei Hsieh-Li, Yuh-Jyh Jong, Nancy M. Wang, Chang-Hai Tsai, and Hung Li Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9808–9813. doi: 10.1073/pnas.171105098.PMCID: PMC55534 Spatial–temporal imaging of bacterial infection and antibiotic
response in intact animals Ming Zhao, Meng Yang, Eugene Baranov, Xiaoen Wang, Sheldon Penman, A. R. Moossa, and Robert M. Hoffman Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9814–9818. Published online 2001 July 31. doi: 10.1073/pnas.161275798.PMCID: PMC55535 Antisense DNAs as multisite genomic modulators identified by
DNA microarray Yee Sook Cho, Meyoung-Kon Kim, Chris Cheadle, Catherine Neary, Kevin G. Becker, and Yoon S. Cho-Chung Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9819–9823. Published online 2001 July 31. doi: 10.1073/pnas.171314398.PMCID: PMC55536 An immune response manifested by the common occurrence of
annexins I and II autoantibodies and high circulating levels of
IL-6 in lung cancer Franck M. Brichory, David E. Misek, Anne-Marie Yim, Melissa C. Krause, Thomas J. Giordano, David G. Beer, and Samir M. Hanash Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9824–9829. doi: 10.1073/pnas.171320598.PMCID: PMC55537 Heart regeneration in adult MRL mice John M. Leferovich, Khamilia Bedelbaeva, Stefan Samulewicz, Xiang-Ming Zhang, Donna Zwas, Edward B. Lankford, and Ellen Heber-Katz Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9830–9835. Published online 2001 August 7. doi: 10.1073/pnas.181329398.PMCID: PMC55538 Acridine and phenothiazine derivatives as pharmacotherapeutics
for prion disease Carsten Korth, Barnaby C. H. May, Fred E. Cohen, and Stanley B. Prusiner Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9836–9841. doi: 10.1073/pnas.161274798.PMCID: PMC55539 A new recommended dietary allowance of vitamin C for healthy
young women Mark Levine, Yaohui Wang, Sebastian J. Padayatty, and Jason Morrow Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9842–9846. doi: 10.1073/pnas.171318198.PMCID: PMC55540 Hepatitis C virus replication is directly inhibited by IFN-α in
a full-length binary expression system Raymond T. Chung, Wenping He, Afroz Saquib, Ana M. Contreras, Ramnik J. Xavier, Ashish Chawla, Timothy C. Wang, and Emmett V. Schmidt Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9847–9852. Published online 2001 August 7. doi: 10.1073/pnas.171319698.PMCID: PMC55541 Microbiology DNA/DNA hybridization to microarrays reveals gene-specific
differences between closely related microbial genomes A. E. Murray, D. Lies, G. Li, K. Nealson, J. Zhou, and J. M. Tiedje Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9853–9858. Published online 2001 August 7. doi: 10.1073/pnas.171178898.PMCID: PMC55542 Cleavage of the human respiratory syncytial virus fusion protein
at two distinct sites is required for activation of membrane
fusion Luis González-Reyes, M. Begoña Ruiz-Argüello, Blanca García-Barreno, Leslie Calder, Juan A. López, Juan P. Albar, John J. Skehel, Don C. Wiley, and José A. Melero Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9859–9864. Published online 2001 August 7. doi: 10.1073/pnas.151098198.PMCID: PMC55543 The evolution of methicillin resistance in Staphylococcus
aureus: Similarity of genetic backgrounds in historically early
methicillin-susceptible and -resistant isolates and contemporary epidemic clones M. Inês Crisóstomo, Henrik Westh, Alexander Tomasz, Marilyn Chung, Duarte C. Oliveira, and Hermínia de Lencastre Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9865–9870. Published online 2001 July 31. doi: 10.1073/pnas.161272898.PMCID: PMC55544 Polar targeting of Shigella virulence factor IcsA
in Enterobacteriacae and Vibrio Macarthur Charles, Marisa Pérez, Jessica H. Kobil, and Marcia B. Goldberg Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9871–9876. Published online 2001 July 31. doi: 10.1073/pnas.171310498.PMCID: PMC55545 From the Cover: Analysis of the chromosome sequence of the legume symbiont
Sinorhizobium meliloti strain 1021 Delphine Capela, Frédérique Barloy-Hubler, Jérôme Gouzy, Gordana Bothe, Frédéric Ampe, Jacques Batut, Pierre Boistard, Anke Becker, Marc Boutry, Edouard Cadieu, Stéphane Dréano, Stéphanie Gloux, Thérèse Godrie, André Goffeau, Daniel Kahn, Ernö Kiss, Valérie Lelaure, David Masuy, Thomas Pohl, Daniel Portetelle, Alfred Pühler, Bénédicte Purnelle, Ulf Ramsperger, Clotilde Renard, Patricia Thébault, Micheline Vandenbol, Stefan Weidner, and Francis Galibert Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9877–9882. Published online 2001 July 31. doi: 10.1073/pnas.161294398.PMCID: PMC55546 From the Cover: Nucleotide sequence and predicted functions of the entire
Sinorhizobium meliloti pSymA megaplasmid Melanie J. Barnett, Robert F. Fisher, Ted Jones, Caridad Komp, A. Pia Abola, Frédérique Barloy-Hubler, Leah Bowser, Delphine Capela, Francis Galibert, Jérôme Gouzy, Mani Gurjal, Andrea Hong, Lucas Huizar, Richard W. Hyman, Daniel Kahn, Michael L. Kahn, Sue Kalman, David H. Keating, Curtis Palm, Melicent C. Peck, Raymond Surzycki, Derek H. Wells, Kuo-Chen Yeh, Ronald W. Davis, Nancy A. Federspiel, and Sharon R. Long Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9883–9888. Published online 2001 July 31. doi: 10.1073/pnas.161294798.PMCID: PMC55547 From the Cover: The complete sequence of the 1,683-kb pSymB megaplasmid from the
N2-fixing endosymbiont
Sinorhizobium meliloti Turlough M. Finan, Stefan Weidner, Kim Wong, Jens Buhrmester, Patrick Chain, Frank J. Vorhölter, Ismael Hernandez-Lucas, Anke Becker, Alison Cowie, Jérôme Gouzy, Brian Golding, and Alfred Pühler Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9889–9894. Published online 2001 July 31. doi: 10.1073/pnas.161294698.PMCID: PMC55548 Exploring the transcriptome of the malaria sporozoite stage Stefan H. I. Kappe, Malcolm J. Gardner, Stuart M. Brown, Jessica Ross, Kai Matuschewski, Jose M. Ribeiro, John H. Adams, John Quackenbush, Jennifer Cho, Daniel J. Carucci, Stephen L. Hoffman, and Victor Nussenzweig Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9895–9900. Published online 2001 August 7. doi: 10.1073/pnas.171185198.PMCID: PMC55549 Peptide methionine sulfoxide reductase from Escherichia
coli and Mycobacterium tuberculosis protects
bacteria against oxidative damage from reactive nitrogen
intermediates Gregory St. John, Nathan Brot, Jia Ruan, Hediye Erdjument-Bromage, Paul Tempst, Herbert Weissbach, and Carl Nathan Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9901–9906. Published online 2001 July 31. doi: 10.1073/pnas.161295398.PMCID: PMC55550 Neurobiology Ethanol hypersensitivity and olfactory discrimination defect in
mice lacking a homolog of Drosophila neuralized Youlin Ruan, Laurence Tecott, Ming-Ming Jiang, Lily Yeh Jan, and Yuh Nung Jan Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9907–9912. Published online 2001 July 31. doi: 10.1073/pnas.171321098.PMCID: PMC55551 Brain glucose utilization in mice with a targeted mutation in the
thyroid hormone α or β receptor gene Yoshiaki Itoh, Takanori Esaki, Masahiro Kaneshige, Hideyo Suzuki, Michelle Cook, Louis Sokoloff, Sheue-Yann Cheng, and Jacques Nunez Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9913–9918. Published online 2001 July 31. doi: 10.1073/pnas.171319498.PMCID: PMC55552 A role for muscarinic excitation: Control of specific singing
behavior by activation of the adenylate cyclase pathway in the brain
of grasshoppers Ralf Heinrich, Beate Wenzel, and Norbert Elsner Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9919–9923. Published online 2001 July 3. doi: 10.1073/pnas.151131998.PMCID: PMC55553 Neural agrin controls acetylcholine receptor stability in
skeletal muscle fibers Gabriela Bezakova, Inger Rabben, Iren Sefland, Guido Fumagalli, and Terje Lømo Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9924–9929. Published online 2001 August 7. doi: 10.1073/pnas.171539698.PMCID: PMC55554 A neurohistochemical blueprint for pain-induced loss of appetite Amy Malick, Moshe Jakubowski, Joel K. Elmquist, Clifford B. Saper, and Rami Burstein Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9930–9935. doi: 10.1073/pnas.171616898.PMCID: PMC55555 Trypanosoma cruzi trans-sialidase:
A potent and specific survival factor for human Schwann cells by
means of phosphatidylinositol 3-kinase/Akt signaling Marina V. Chuenkova, Frank B. Furnari, Webster K. Cavenee, and Miercio A. Pereira Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9936–9941. Published online 2001 July 31. doi: 10.1073/pnas.161298398.PMCID: PMC55556 Subretinal transplantation of genetically modified human cell
lines attenuates loss of visual function in dystrophic rats Raymond D. Lund, Peter Adamson, Yves Sauvé, David J. Keegan, Sergej V. Girman, Shaomei Wang, Helen Winton, Naheed Kanuga, Anthony S. L. Kwan, Laurence Beauchène, Anne Zerbib, Len Hetherington, Pierre-Olivier Couraud, Peter Coffey, and John Greenwood Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9942–9947. doi: 10.1073/pnas.171266298.PMCID: PMC55557 Role of guanylate cyclase-activating proteins (GCAPs) in setting
the flash sensitivity of rod photoreceptors Ana Mendez, Marie E. Burns, Izabela Sokal, Alexander M. Dizhoor, Wolfgang Baehr, Krzysztof Palczewski, Denis A. Baylor, and Jeannie Chen Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9948–9953. Published online 2001 August 7. doi: 10.1073/pnas.171308998.PMCID: PMC55558 Role of glutamate δ-2 receptors in activity-dependent
competition between heterologous afferent fibers Laura Morando, Roberta Cesa, Roberta Rasetti, Robin Harvey, and Piergiorgio Strata Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9954–9959. Published online 2001 August 7. doi: 10.1073/pnas.171098398.PMCID: PMC55559 Receptor subtype-specific pronociceptive and analgesic actions of
galanin in the spinal cord: Selective actions via GalR1 and
GalR2 receptors Hong-Xiang Liu, Pablo Brumovsky, Ralf Schmidt, William Brown, Kemal Payza, Lejla Hodzic, Chantevy Pou, Claude Godbout, and Tomas Hökfelt Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9960–9964. Published online 2001 July 31. doi: 10.1073/pnas.161293598.PMCID: PMC55560 Arousal effect of orexin A depends on activation of the
histaminergic system Zhi-Li Huang, Wei-Min Qu, Wei-Dong Li, Takatoshi Mochizuki, Naomi Eguchi, Takeshi Watanabe, Yoshihiro Urade, and Osamu Hayaishi Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9965–9970. Published online 2001 August 7. doi: 10.1073/pnas.181330998.PMCID: PMC55561 Identification of peptides from brain and pituitary of
Cpefat/Cpefat mice Fa-Yun Che, Lin Yan, Hong Li, Nino Mzhavia, Lakshmi A. Devi, and Lloyd D. Fricker Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9971–9976. Published online 2001 July 31. doi: 10.1073/pnas.161542198.PMCID: PMC55562 Pharmacology Heart-targeted overexpression of caspase3 in mice
increases infarct size and depresses cardiac function Gianluigi Condorelli, Roberta Roncarati, John Ross, Jr., Angela Pisani, Giorgio Stassi, Matilde Todaro, Stephen Trocha, Alessandra Drusco, Yusu Gu, Matteo A. Russo, Giacomo Frati, Steven P. Jones, David J. Lefer, Claudio Napoli, and Carlo M. Croce Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9977–9982. Published online 2001 August 7. doi: 10.1073/pnas.161120198.PMCID: PMC55563 Physiology Mediation of tubuloglomerular feedback by adenosine: Evidence
from mice lacking adenosine 1 receptors Daqing Sun, Linda C. Samuelson, Tianxin Yang, Yuning Huang, Alex Paliege, Thom Saunders, Josie Briggs, and Jurgen Schnermann Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9983–9988. doi: 10.1073/pnas.171317998.PMCID: PMC55564 Endothelial cell-specific knockout of connexin 43 causes
hypotension and bradycardia in mice Y. Liao, K. H. Day, D. N. Damon, and B. R. Duling Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9989–9994. Published online 2001 July 31. doi: 10.1073/pnas.171305298.PMCID: PMC55565 Plant Biology Functional activity and role of cation-efflux family members in
Ni hyperaccumulation in Thlaspi goesingense Michael W. Persans, Ken Nieman, and David E. Salt Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 9995–10000. Published online 2001 July 31. doi: 10.1073/pnas.171039798.PMCID: PMC55566 Enhanced synthesis of choline and glycine betaine in transgenic
tobacco plants that overexpress
phosphoethanolamine N-methyltransferase Scott D. McNeil, Michael L. Nuccio, Michael J. Ziemak, and Andrew D. Hanson Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10001–10005. Published online 2001 July 31. doi: 10.1073/pnas.171228998.PMCID: PMC55567 Psychology Crossmodal binding of fear in voice and face R. J. Dolan, J. S. Morris, and B. de Gelder Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10006–10010. Published online 2001 August 7. doi: 10.1073/pnas.171288598.PMCID: PMC55568 Social Sciences Anthropology A cranium for the earliest Europeans: Phylogenetic position of
the hominid from Ceprano, Italy G. Manzi, F. Mallegni, and A. Ascenzi Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10011–10016. doi: 10.1073/pnas.151259998.PMCID: PMC55569 Old World sources of the first New World human inhabitants: A
comparative craniofacial view C. Loring Brace, A. Russell Nelson, Noriko Seguchi, Hiroaki Oe, Leslie Sering, Pan Qifeng, Li Yongyi, and Dashtseveg Tumen Proc Natl Acad Sci U S A. 2001 August 14; 98(17): 10017–10022. Published online 2001 July 31. doi: 10.1073/pnas.171305898.PMCID: PMC55570 |