Functional gene cassettes in development.

Implications for conserved genomic structure among plant species.

Cognitive kinases.

Transgenic mouse models of lipoprotein metabolism and atherosclerosis.

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

The isolation of molecular genetic markers for the identification of sex.

Human platelet glycoprotein V: characterization of the polypeptide and the related Ib-V-IX receptor system of adhesive, leucine-rich glycoproteins.

Polarization of yeast cells in spatial gradients of alpha mating factor.

Mechanism of protein kinase C activation during the induction and maintenance of long-term potentiation probed using a selective peptide substrate.

Persistent activation of the zeta isoform of protein kinase C in the maintenance of long-term potentiation.

Stereocilia displacement induced somatic motility of cochlear outer hair cells.

Cloning, sequencing, and expression of the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii.

Cooperative and anticooperative binding to a ribozyme.

Guanosine binding to the Tetrahymena ribozyme: thermodynamic coupling with oligonucleotide binding.

Engineering multiple properties of a protein by combinatorial mutagenesis.

Expression of bovine vitamin K-dependent carboxylase activity in baculovirus-infected insect cells.

Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients.

Yeast GAL11 protein is a distinctive type transcription factor that enhances basal transcription in vitro.

Crystal structure of human immunodeficiency virus (HIV) type 2 protease in complex with a reduced amide inhibitor and comparison with HIV-1 protease structures.

Production of high-titer helper-free retroviruses by transient transfection.

FimC is a periplasmic PapD-like chaperone that directs assembly of type 1 pili in bacteria.

What determines the strength of noncovalent association of ligands to proteins in aqueous solution?

DNA topoisomerase II alpha is the major chromosome protein recognized by the mitotic phosphoprotein antibody MPM-2.

Fighting for a harem of queens: physiology of reproduction in Cardiocondyla male ants.

Gamma delta T cells differentiate into a functional but nonproliferative state during a normal immune response.

Agricultural soil fumigation as a source of atmospheric methyl bromide.

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

Molecular distinction of three N-methyl-D-aspartate-receptor subtypes in situ and developmental receptor maturation demonstrated with the photoaffinity ligand 125I-labeled CGP 55802A.

Cloning and tissue-specific functional characterization of the promoter of the rat diazepam binding inhibitor, a peptide with multiple biological actions.

Physical interaction between the herpes simplex virus 1 origin-binding protein and single-stranded DNA-binding protein ICP8.

Transcription factor TFIID recognizes DNA sequences downstream of the TATA element in the Hsp70 heat shock gene.

Polyunsaturated fatty acids inhibit S14 gene transcription in rat liver and cultured hepatocytes.

The role of active-site aromatic and polar residues in catalysis and substrate discrimination by xylose isomerase.

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

An "in-out" strategy using gene targeting and FLP recombinase for the functional dissection of complex DNA regulatory elements: analysis of the beta-globin locus control region.

Single intraluminal delivery of antisense cdc2 kinase and proliferating-cell nuclear antigen oligonucleotides results in chronic inhibition of neointimal hyperplasia.

Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death.

Cellular interactions implicated in the mechanism of photoreceptor degeneration in transgenic mice expressing a mutant rhodopsin gene.

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein.

Polyoma virus early-late switch: regulation of late RNA accumulation by DNA replication.

Substrate-assisted catalysis in the cleavage of DNA by the EcoRI and EcoRV restriction enzymes.

Mitogenic activation of the Ras guanine nucleotide exchange factor in NIH 3T3 cells involves protein tyrosine phosphorylation.

Positional cloning of the hereditary renal carcinoma 3;8 chromosome translocation breakpoint.

Genomic organization of the melanoma-associated glycoprotein MUC18: implications for the evolution of the immunoglobulin domains.

Molecular cloning of an allene oxide synthase: a cytochrome P450 specialized for the metabolism of fatty acid hydroperoxides.

Cysteine-102 is positioned in the metal binding activation site of the Corynebacterium diphtheriae regulatory element DtxR.

Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1.

Expression of 300-kilodalton intermediate filament-associated protein distinguishes human glioma cells from normal astrocytes.

Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation.

Staphylococcal enterotoxins can reactivate experimental allergic encephalomyelitis.

Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.

Stromal factor plays an essential role in protein integration into thylakoids that cannot be replaced by unfolding or by heat shock protein Hsp70.

Isoprenylation of the plant molecular chaperone ANJ1 facilitates membrane association and function at high temperature.

Nucleation of hydroxyapatite by bone sialoprotein.

In vitro analysis of Ah receptor domains involved in ligand-activated DNA recognition.

Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro.

Expression of mammalian glutathione S-transferase 5-5 in Salmonella typhimurium TA1535 leads to base-pair mutations upon exposure to dihalomethanes.

Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization.

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes.

Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptors.

Giardiavirus double-stranded RNA genome encodes a capsid polypeptide and a gag-pol-like fusion protein by a translation frameshift.

Crystal structures of the monofunctional chorismate mutase from Bacillus subtilis and its complex with a transition state analog.

Asparagine 229 in thymidylate synthase contributes to, but is not essential for, catalysis.

Isolation of virulence genes directing surface glycosyl-phosphatidylinositol synthesis by functional complementation of Leishmania.

Ciliary neurotrophic factor is an endogenous pyrogen.

Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum.

Inverse splicing of a group II intron.

Characterization of distinct functional domains of transforming growth factor beta.

Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes.

T- and B-cell functions and epitope expression in nonhuman primates immunized with simian immunodeficiency virus antigen by the rectal route.

Microphotocoagulation: selective effects of repetitive short laser pulses.

Heat shock of Escherichia coli increases binding of dnaK (the hsp70 homolog) to polypeptides by promoting its phosphorylation.

Enzyme crystal structure in a neat organic solvent.

A model of human immunodeficiency virus encephalitis in scid mice.

Binding of a high-energy substrate conformer in antibody catalysis.

Transfected human liver cytochrome P-450 hydroxylates vitamin D analogs at different side-chain positions.

Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides.

Platelet-activating factor induces collagenase expression in corneal epithelial cells.

GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.

Multiple origins of advanced eusociality in bees inferred from mitochondrial DNA sequences.

Evidence for a chimeric nature of nuclear genomes: eubacterial origin of eukaryotic glyceraldehyde-3-phosphate dehydrogenase genes.

Chronic lymphocytic leukemia cells with allelic deletions at 13q14 commonly have one intact RB1 gene: evidence for a role of an adjacent locus.

A model for tumor suppression using H-1 parvovirus.

Release from quiescence of CD34+ CD38- human umbilical cord blood cells reveals their potentiality to engraft adults.

Amyloid precursor protein in the cerebral cortex is rapidly and persistently induced by loss of subcortical innervation.

Chimeric tumor necrosis factor-TrkA receptors reveal that ligand-dependent activation of the TrkA tyrosine kinase is sufficient for differentiation and survival of PC12 cells.

Modulation of early sensory processing in human auditory cortex during auditory selective attention.

Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.

Molecular cloning and characterization of rho, a ras-related small GTP-binding protein from the garden pea.

Identification of a yeast artificial chromosome clone encoding an accessory factor for the human interferon gamma receptor: evidence for multiple accessory factors.

Immunochemical detection of 4-hydroxynonenal protein adducts in oxidized hepatocytes.

Prevention of experimental autoimmune myasthenia gravis by manipulation of the immune network with a complementary peptide for the acetylcholine receptor.

Recombinant human insulin-like growth factor I exerts a trophic action and confers glutamate sensitivity on glutamate-resistant cerebellar granule cells.

A highly polymorphic microsatellite in the class II Eb gene allows tracing of major histocompatibility complex evolution in mouse