| | This journal provides immediate access to some articles. Commentaries Long terminal repeat retrotransposons jump between species Andrew J. Flavell Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12211–12212. PMCID: PMC34249 Calcium from internal stores modifies dendritic spine shape Kristen M. Harris Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12213–12215. PMCID: PMC34250 Cancer prevention and diet: Help from single
nucleotide polymorphisms Bruce N. Ames Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12216–12218. PMCID: PMC34251 Making sense of polymer-based biosensors Peter S. Heeger and Alan J. Heeger Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12219–12221. PMCID: PMC34252 Delineating muscarinic receptor functions Raul R. Gainetdinov and Marc G. Caron Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12222–12223. PMCID: PMC34253 Bridging the gap: A family of novel DNA polymerases that
replicate faulty DNA Robert E. Johnson, M. Todd Washington, Satya Prakash, and Louise Prakash Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12224–12226. PMCID: PMC34254 SNARE proteins mediate lipid bilayer fusion Jason B. Bock and Richard H. Scheller Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12227–12229. PMCID: PMC34255 VHL: A very hip ligase Mike Tyers and Rob Rottapel Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12230–12232. PMCID: PMC34256 Review The metabolic implications of intracellular circulation P. W. Hochachka Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12233–12239. PMCID: PMC34257 Physical Sciences Applied Mathematics Energetic considerations of ciliary beating and the advantage of metachronal coordination Shay Gueron and Konstantin Levit-Gurevich Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12240–12245. PMCID: PMC22900 Chemistry Reptilian chemistry: Characterization of dianeackerone, a secretory product from a crocodile Authrine Whyte, Zhi-Cai Yang, Kittichoat Tiyanont, Paul J. Weldon, Thomas Eisner, and Jerrold Meinwald Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12246–12250. PMCID: PMC22901 Reptilian chemistry: Characterization of a family of dianeackerone-related steroidal esters from a crocodile secretion Zhicai Yang, Authrine Whyte, Athula B. Attygalle, Paul J. Weldon, Thomas Eisner, and Jerrold Meinwald Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12251–12256. PMCID: PMC22902 Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor Patricia Andrade-Gordon, Bruce E. Maryanoff, Claudia K. Derian, Han-Cheng Zhang, Michael F. Addo, Andrew L. Darrow, Annette J. Eckardt, William J. Hoekstra, David F. McComsey, Donna Oksenberg, Elwood E. Reynolds, Rosemary J. Santulli, Robert M. Scarborough, Charles E. Smith, and Kimberly B. White Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12257–12262. PMCID: PMC22903 Mathematics Solution of the pulse width modulation problem using orthogonal polynomials and Korteweg-de Vries equations D. V. Chudnovsky and G. V. Chudnovsky Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12263–12268. PMCID: PMC22904 Physics Pressure-enhanced ortho-para conversion in solid hydrogen up to 58 GPa Jon H. Eggert, Eran Karmon, Russell J. Hemley, Ho-kwang Mao, and Alexander F. Goncharov Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12269–12272. PMCID: PMC22905 Statistics Derived variables for longitudinal studies D. R. Cox and Nanny Wermuth Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12273–12274. PMCID: PMC22906 Biological Sciences Agricultural Sciences Identification of lumichrome as a Sinorhizobium enhancer of alfalfa root respiration and shoot growth Donald A. Phillips, Cecillia M. Joseph, Guo-Ping Yang, Esperanza Martínez-Romero, James R. Sanborn, and Hanne Volpin Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12275–12280. PMCID: PMC22907 Anthropology Direct radiocarbon dates for Vindija G1 and Velika Pećina Late Pleistocene hominid remains Fred H. Smith, Erik Trinkaus, Paul B. Pettitt, Ivor Karavanić, and Maja Paunović Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12281–12286. PMCID: PMC22908 Applied Biological Sciences From the Cover: Highly sensitive biological and chemical sensors based on reversible fluorescence quenching in a conjugated polymer Liaohai Chen, Duncan W. McBranch, Hsing-Lin Wang, Roger Helgeson, Fred Wudl, and David G. Whitten Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12287–12292. PMCID: PMC22909 DNA packing in stable lipid complexes designed for gene transfer imitates DNA compaction in bacteriophage M. Schmutz, D. Durand, A. Debin, Y. Palvadeau, A. Etienne, and A. R. Thierry Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12293–12298. PMCID: PMC22910 Biochemistry Three metal ions at the active site of the Tetrahymena group I ribozyme Shu-ou Shan, Aiichiro Yoshida, Sengen Sun, Joseph A. Piccirilli, and Daniel Herschlag Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12299–12304. PMCID: PMC22911 A structural view of evolutionary divergence Ben Spiller, Anne Gershenson, Frances H. Arnold, and Raymond C. Stevens Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12305–12310. PMCID: PMC22912 Targeting a SWI/SNF-related chromatin remodeling complex to the β-globin promoter in erythroid cells Chang-Hun Lee, Michael R. Murphy, Jong-Soo Lee, and Jay H. Chung Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12311–12315. PMCID: PMC22913 Assembly of a catalytic unit for RNA microhelix aminoacylation using nonspecific RNA binding domains Joseph W. Chihade and Paul Schimmel Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12316–12321. PMCID: PMC22914 Conversion of agonist site to metal-ion chelator site in the β2-adrenergic receptor Christian E. Elling, Kenneth Thirstrup, Birgitte Holst, and Thue W. Schwartz Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12322–12327. PMCID: PMC22915 NMR characterization of lignins in Arabidopsis altered in the activity of ferulate 5-hydroxylase Jane M. Marita, John Ralph, Ronald D. Hatfield, and Clint Chapple Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12328–12332. PMCID: PMC22916 Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product Shoko Hirotsu, Yasuko Abe, Kengo Okada, Noriyuki Nagahara, Hiroyuki Hori, Takeshi Nishino, and Toshio Hakoshima Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12333–12338. PMCID: PMC22917 Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly Hiep-Hoa T. Nguyen, Jie Ge, Deborah L. Perlstein, and JoAnne Stubbe Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12339–12344. PMCID: PMC22918 A protein residing at the subunit interface of the bacterial ribosome Dmitry E. Agafonov, Vyacheslav A. Kolb, Igor V. Nazimov, and Alexander S. Spirin Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12345–12349. PMCID: PMC22919 Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1 Young Ho Kim, Cheol Yong Choi, and Yongsok Kim Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12350–12355. PMCID: PMC22920 Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity Andrew A. Carmen, Patrick R. Griffin, Jimmy R. Calaycay, Stephen E. Rundlett, Yuko Suka, and Michael Grunstein Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12356–12361. PMCID: PMC22921 The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis Shoji Sugano, Christos Andronis, May S. Ong, Rachel M. Green, and Elaine M. Tobin Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12362–12366. PMCID: PMC22922 Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe Kyeong-Yeop Moon, Daochun Kong, Joon-Kyu Lee, Santanu Raychaudhuri, and Jerard Hurwitz Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12367–12372. PMCID: PMC22923 The Escherichia coli SOS mutagenesis proteins UmuD and UmuD′ interact physically with the replicative DNA polymerase Mark D. Sutton, Timothy Opperman, and Graham C. Walker Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12373–12378. PMCID: PMC22924 Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus Andrea Carfí, Craig A. Smith, Pamela J. Smolak, Jeffrey McGrew, and Don C. Wiley Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12379–12383. PMCID: PMC22925 hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage Derek R. Duckett, S. Maynard Bronstein, Yoichi Taya, and Paul Modrich Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12384–12388. PMCID: PMC22926 In Azotobacter vinelandii, the E1 subunit of the pyruvate dehydrogenase complex binds fpr promoter region DNA and ferredoxin I Karin Regnström, Sandrine Sauge-Merle, Kaisheng Chen, and Barbara K. Burgess Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12389–12393. PMCID: PMC22927 Mobilization of the A-kinase N-myristate through an isoform-specific intermolecular switch Milind Gangal, Teresa Clifford, Jason Deich, Xiaodong Cheng, Susan S. Taylor, and David A. Johnson Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12394–12399. PMCID: PMC22929 Isolation of a Chinese hamster ovary cell mutant defective in intramitochondrial transport of phosphatidylserine Kazuo Emoto, Osamu Kuge, Masahiro Nishijima, and Masato Umeda Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12400–12405. PMCID: PMC22930 RNase E is required for the maturation of ssrA RNA and normal ssrA RNA peptide-tagging activity Sue Lin-Chao, Chia-Li Wei, and Yi-Tzu Lin Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12406–12411. PMCID: PMC22933 Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue Xianwen Yi, Mark Mroczko, Kelath M. Manoj, Xiaotang Wang, and Lowell P. Hager Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12412–12417. PMCID: PMC22935 Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity Ehab M. Khalil, Jacqueline De Angelis, Makoto Ishii, and Philip A. Cole Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12418–12423. PMCID: PMC22936 Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif Hung Ton-That, Gwen Liu, Sarkis K. Mazmanian, Kym F. Faull, and Olaf Schneewind Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12424–12429. PMCID: PMC22937 Translocation and specific cleavage of bacteriophage T7 DNA in vivo by EcoKI L. René García and Ian J. Molineux Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12430–12435. PMCID: PMC22939 From the Cover: Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex Kazuhiro Iwai, Koji Yamanaka, Takumi Kamura, Nagahiro Minato, Ronald C. Conaway, Joan W. Conaway, Richard D. Klausner, and Arnim Pause Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12436–12441. PMCID: PMC22941 SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling Yin Sun, Xuedong Liu, Elinor Ng-Eaton, Harvey F. Lodish, and Robert A. Weinberg Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12442–12447. PMCID: PMC22943 Opening of a monomer-monomer interface of the trimeric bacteriophage T4-coded GP45 sliding clamp is required for clamp loading onto DNA Gary J. Latham, Feng Dong, Paola Pietroni, Jody M. Dozono, Daniel J. Bacheller, and Peter H. von Hippel Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12448–12453. PMCID: PMC22945 Ku is associated with the telomere in mammals Hsin-Ling Hsu, David Gilley, Elizabeth H. Blackburn, and David J. Chen Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12454–12458. PMCID: PMC22947 Rapid treadmilling of brain microtubules free of microtubule-associated proteins in vitro and its suppression by tau Dulal Panda, Herbert P. Miller, and Leslie Wilson Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12459–12464. PMCID: PMC22948 The solution structure of the Zα domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA Markus Schade, Christopher J. Turner, Ronald Kühne, Peter Schmieder, Ky Lowenhaupt, Alan Herbert, Alexander Rich, and Hartmut Oschkinat Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12465–12470. PMCID: PMC22950 An optimal Mg2+ concentration for kinetic folding of the Tetrahymena ribozyme Martha S. Rook, Daniel K. Treiber, and James R. Williamson Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12471–12476. PMCID: PMC22953 Biophysics The use of site-directed fluorophore labeling and donor–donor energy migration to investigate solution structure and dynamics in proteins Fredrik Bergström, Peter Hägglöf, Jan Karolin, Tor Ny, and Lennart B.-Å. Johansson Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12477–12481. PMCID: PMC22954 Folding protein models with a simple hydrophobic energy function: The fundamental importance of monomer inside/outside segregation Antônio F. Pereira de Araújo Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12482–12487. PMCID: PMC22956 Tropomyosin directly modulates actomyosin mechanical performance at the level of a single actin filament Peter VanBuren, Kimberly A. Palmiter, and David M. Warshaw Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12488–12493. PMCID: PMC22958 Measures of residue density in protein structures Franck Baud and Samuel Karlin Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12494–12499. PMCID: PMC22960 Atom density in protein structures Samuel Karlin, Zhan-Yang Zhu, and Franck Baud Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12500–12505. PMCID: PMC22962 Odor space and olfactory processing: Collective algorithms and
neural implementation J. J. Hopfield Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12506–12511. PMCID: PMC22963 Exploring the origins of topological frustration: Design of a minimally frustrated model of fragment B of protein A Joan-Emma Shea, José N. Onuchic, and Charles L. Brooks, III Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12512–12517. PMCID: PMC22965 Self-assembly of fibronectin into fibrillar networks underneath dipalmitoyl phosphatidylcholine monolayers: Role of lipid matrix and tensile forces Gretchen Baneyx and Viola Vogel Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12518–12523. PMCID: PMC22966 Structure-based conformational preferences of amino acids Patrice Koehl and Michael Levitt Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12524–12529. PMCID: PMC22969 Cell Biology Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor Patricia Andrade-Gordon, Bruce E. Maryanoff, Claudia K. Derian, Han-Cheng Zhang, Michael F. Addo, Andrew L. Darrow, Annette J. Eckardt, William J. Hoekstra, David F. McComsey, Donna Oksenberg, Elwood E. Reynolds, Rosemary J. Santulli, Robert M. Scarborough, Charles E. Smith, and Kimberly B. White Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12257–12262. PMCID: PMC22903 Effectors of a developmental mitogen-activated protein kinase cascade revealed by expression signatures of signaling mutants H. D. Madhani, T. Galitski, E. S. Lander, and G. R. Fink Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12530–12535. PMCID: PMC22972 A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2 Victor S. Goldmacher, Laura M. Bartle, Anna Skaletskaya, Cheryl A. Dionne, Nancy L. Kedersha, Carol A. Vater, Jia-wen Han, Robert J. Lutz, Shinya Watanabe, Ellen D. Cahir McFarland, Elliott D. Kieff, Edward S. Mocarski, and Thomas Chittenden Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12536–12541. PMCID: PMC22976 The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein Heather Morehouse, Robin M. Buratowski, Pamela A. Silver, and Stephen Buratowski Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12542–12547. PMCID: PMC22979 Casein kinase I ![[var epsilon]](corehtml/pmc/pmcents/epsiv.gif) in the Wnt pathway: Regulation of β-catenin function Chie Sakanaka, Peng Leong, Licen Xu, Stephen D. Harrison, and Lewis T. Williams Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12548–12552. PMCID: PMC22983 Tumor burden and clonality in multiple intestinal neoplasia mouse/normal mouse aggregation chimeras Marco R. Novelli, Harpreet Wasan, Ian Rosewell, Julie Bee, Ian P. Tomlinson, Nicholas A. Wright, and Walter F. Bodmer Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12553–12558. PMCID: PMC22985 Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor Yuting Tang, Liaoyuan A. Hu, William E. Miller, Niels Ringstad, Randy A. Hall, Julie A. Pitcher, Pietro DeCamilli, and Robert J. Lefkowitz Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12559–12564. PMCID: PMC22990 Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain Francesco Parlati, Thomas Weber, James A. McNew, Benedikt Westermann, Thomas H. Söllner, and James E. Rothman Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12565–12570. PMCID: PMC22992 Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs Walter Nickel, Thomas Weber, James A. McNew, Francesco Parlati, Thomas H. Söllner, and James E. Rothman Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12571–12576. PMCID: PMC22994 The active digestion of uniparental chloroplast DNA in a single zygote of Chlamydomonas reinhardtii is revealed by using the optical tweezer Yoshiki Nishimura, Osami Misumi, Sachihiro Matsunaga, Tetsuya Higashiyama, Akiho Yokota, and Tsuneyoshi Kuroiwa Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12577–12582. PMCID: PMC22996 Calcium-independent activation of endothelial nitric oxide synthase by ceramide Junsuke Igarashi, Hemant S. Thatte, Prakash Prabhakar, David E. Golan, and Thomas Michel Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12583–12588. PMCID: PMC22998 Proteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties Martin J. Page, Bob Amess, R. Reid Townsend, Raj Parekh, Athula Herath, Luc Brusten, Marketa J. Zvelebil, Robert C. Stein, Michael D. Waterfield, Susan C. Davies, and Michael J. O’Hare Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12589–12594. PMCID: PMC23001 Developmental Biology Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis Joerg Heyer, Diana Escalante-Alcalde, Marie Lia, Erwin Boettinger, Winfried Edelmann, Colin L. Stewart, and Raju Kucherlapati Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12595–12600. PMCID: PMC23005 Developmental exposure to vasopressin increases aggression in adult prairie voles John M. Stribley and C. Sue Carter Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12601–12604. PMCID: PMC23008 The STAR protein QKI-6 is a translational repressor Lisa Saccomanno, Carrie Loushin, Eric Jan, Eric Punkay, Karen Artzt, and Elizabeth B. Goodwin Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12605–12610. PMCID: PMC23011 Ecology Self-organized defensive behavior in honeybees J. Millor, M. Pham-Delegue, J. L. Deneubourg, and S. Camazine Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12611–12615. PMCID: PMC23012 Evolution From the Cover: Two living species of coelacanths? Mark T. Holder, Mark V. Erdmann, Thomas P. Wilcox, Roy L. Caldwell, and David M. Hillis Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12616–12620. PMCID: PMC23015 From the Cover: Evidence for the recent horizontal transfer of long terminal repeat retrotransposon I. King Jordan, Lilya V. Matyunina, and John F. McDonald Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12621–12625. PMCID: PMC23018 Macroevolution of insect–plant associations: The relevance of host biogeography to host affiliation Judith X. Becerra and D. Lawrence Venable Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12626–12631. PMCID: PMC23020 All males are not created equal: Fertility differences depend on gamete recognition polymorphisms in sea urchins Stephen R. Palumbi Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12632–12637. PMCID: PMC23023 Calibrating bacterial evolution Howard Ochman, Susannah Elwyn, and Nancy A. Moran Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12638–12643. PMCID: PMC23026 Signaling of need, sibling competition, and the cost of honesty Rufus A. Johnstone Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12644–12649. PMCID: PMC23029 Genetics Profound misregulation of muscle-specific gene expression in facioscapulohumeral muscular dystrophy Rossella Tupler, Giovanni Perini, Maria Antonietta Pellegrino, and Michael R. Green Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12650–12654. PMCID: PMC23032 Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation D. Gachotte, S. E. Sen, J. Eckstein, R. Barbuch, M. Krieger, B. D. Ray, and M. Bard Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12655–12660. PMCID: PMC23033 Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers Shannon A. Kuismanen, Mari T. Holmberg, Reijo Salovaara, Pascal Schweizer, Lauri A. Aaltonen, Albert de la Chapelle, Minna Nyström-Lahti, and Päivi Peltomäki Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12661–12666. PMCID: PMC23037 LFG: An anti-apoptotic gene that provides protection from Fas-mediated cell death Nikunj V. Somia, Mark J. Schmitt, Douglas E. Vetter, Daniel Van Antwerp, Stephen F. Heinemann, and Inder M. Verma Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12667–12672. PMCID: PMC23041 A genetic method for dissecting the mechanism of transcriptional activator synergy by identical activators Robert C. Langdon and Ann Hochschild Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12673–12678. PMCID: PMC23043 The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components Bee Na Lee and Elaine A. Elion Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12679–12684. PMCID: PMC23046 Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred Alan T. Remaley, Stephan Rust, Marie Rosier, Cathy Knapper, Laurent Naudin, Cyril Broccardo, Katherine M. Peterson, Christine Koch, Isabelle Arnould, Catherine Prades, Nicholas Duverger, Harald Funke, Gerd Assman, Maria Dinger, Michael Dean, Giovanna Chimini, Silvia Santamarina-Fojo, Donald S. Fredrickson, Patrice Denefle, and H. Bryan Brewer, Jr. Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12685–12690. PMCID: PMC23050 Immunology Activation changes the spectrum but not the diversity of genes expressed by T cells T. Kent Teague, David Hildeman, Ross M. Kedl, Tom Mitchell, William Rees, Brian C. Schaefer, Jeremy Bender, John Kappler, and Philippa Marrack Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12691–12696. PMCID: PMC23052 From the Cover: BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes simplex virus 1 Mark Suter, Andrew M. Lew, Philipp Grob, Gosse J. Adema, Mathias Ackermann, Ken Shortman, and Cornel Fraefel Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12697–12702. PMCID: PMC23055 CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose Christian Kurts, Robyn M. Sutherland, Gayle Davey, Ming Li, Andrew M. Lew, Effrossini Blanas, Francis R. Carbone, Jacques F. A. P. Miller, and William R. Heath Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12703–12707. PMCID: PMC23058 Humoral response to herpes simplex virus is complement-dependent Xavier J. Da Costa, Mark A. Brockman, Elisabeth Alicot, Minghe Ma, Michael B. Fischer, Xioaning Zhou, David M. Knipe, and Michael C. Carroll Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12708–12712. PMCID: PMC23060 RAG2 is regulated differentially in B and T cells by elements 5′ of the promoter Robert J. Monroe, Feng Chen, Roger Ferrini, Laurie Davidson, and Frederick W. Alt Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12713–12718. PMCID: PMC23063 Medical Sciences In vivo inhibition of rat stellate cell activation by soluble transforming growth factor β type II receptor: A potential new therapy for hepatic fibrosis Jacob George, Dominique Roulot, Victor E. Koteliansky, and D. Montgomery Bissell Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12719–12724. PMCID: PMC23066 Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein Melissa Burton, Hiroyuki Nakai, Peter Colosi, Janet Cunningham, Rachel Mitchell, and Linda Couto Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12725–12730. PMCID: PMC23069 Nrf2 is essential for protection against acute pulmonary injury in mice Kaimin Chan and Yuet Wai Kan Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12731–12736. PMCID: PMC23072 Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes Marc Foretz, Colette Guichard, Pascal Ferré, and Fabienne Foufelle Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12737–12742. PMCID: PMC23076 Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection Pierre A. Buffet, Benoit Gamain, Christine Scheidig, Dror Baruch, Joseph D. Smith, Rosaura Hernandez-Rivas, Bruno Pouvelle, Shinya Oishi, Nobutaka Fujii, Thierry Fusai, Daniel Parzy, Louis H. Miller, Jürg Gysin, and Artur Scherf Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12743–12748. PMCID: PMC23079 Dose-response resistance to HIV-1/MuLV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model Michael Andäng, Jorma Hinkula, Graham Hotchkiss, Sten Larsson, Sven Britton, Flossie Wong-Staal, Britta Wahren, and Lars Ährlund-Richter Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12749–12753. PMCID: PMC23081 In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis Gerard J. Nuovo, Todd W. Plaia, Steven A. Belinsky, Stephen B. Baylin, and James G. Herman Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12754–12759. PMCID: PMC23084 A mechanism of paraquat toxicity involving nitric oxide synthase Brian J. Day, Manisha Patel, Lisa Calavetta, Ling-Yi Chang, and Jonathan S. Stamler Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12760–12765. PMCID: PMC23088 Hepatitis C virus and other Flaviviridae viruses enter cells via low density lipoprotein receptor Vincent Agnello, György Ábel, Mutasim Elfahal, Glenn B. Knight, and Qing-Xiu Zhang Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12766–12771. PMCID: PMC23090 Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules Jean-Philippe Girard, Espen S. Baekkevold, Jacques Feliu, Per Brandtzaeg, and François Amalric Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12772–12777. PMCID: PMC23093 Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin Markus Gerhard, Norbert Lehn, Nina Neumayer, Thomas Borén, Roland Rad, Wolfgang Schepp, Stephan Miehlke, Meinhard Classen, and Christian Prinz Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12778–12783. PMCID: PMC23096 Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: Role of epsilon protein kinase C Che-Hong Chen, Mary O. Gray, and Daria Mochly-Rosen Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12784–12789. PMCID: PMC23099 INAUGURAL ARTICLE by a Recently Elected Academy Member: Steroid disorders in children: Congenital adrenal hyperplasia and apparent mineralocorticoid excess Maria I. New and Robert C. Wilson Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12790–12797. PMCID: PMC23101 Sustained in vivo cardiac protection by a rationally designed peptide that causes ![[var epsilon]](corehtml/pmc/pmcents/epsiv.gif) protein kinase C translocation Gerald W. Dorn, II, Miriam C. Souroujon, Tamar Liron, Che-Hong Chen, Mary O. Gray, Hui Zhong Zhou, Michael Csukai, Guangyu Wu, John N. Lorenz, and Daria Mochly-Rosen Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12798–12803. PMCID: PMC23103 Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia Xiaoyan Jiang, Angel Lopez, Tessa Holyoake, Allen Eaves, and Connie Eaves Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12804–12809. PMCID: PMC23105 Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults Christine F. Skibola, Martyn T. Smith, Eleanor Kane, Eve Roman, Sara Rollinson, Raymond A. Cartwright, and Gareth Morgan Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12810–12815. PMCID: PMC23109 Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons Núria Morral, Wanda O’Neal, Karen Rice, Michele Leland, Johanne Kaplan, Pedro A. Piedra, Heshan Zhou, Robin J. Parks, Rizwan Velji, Estuardo Aguilar-Córdova, Samuel Wadsworth, Frank L. Graham, Stefan Kochanek, K. Dee Carey, and Arthur L. Beaudet Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12816–12821. PMCID: PMC23112 The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor Bart Lutterbach, Yue Hou, Kristie L. Durst, and Scott W. Hiebert Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12822–12827. PMCID: PMC23113 Microbiology A conserved residue in the tip proteins of CS1 and CFA/I pili of enterotoxigenic Escherichia coli that is essential for adherence Harry Sakellaris, George P. Munson, and June R. Scott Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12828–12832. PMCID: PMC23117 Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization Michael Wilson, Joseph DeRisi, Hans-Henrik Kristensen, Paul Imboden, Sangeeta Rane, Patrick O. Brown, and Gary K. Schoolnik Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12833–12838. PMCID: PMC23119 Reciprocal secretion of proteins by the bacterial type III machines of plant and animal pathogens suggests universal recognition of mRNA targeting signals Deborah M. Anderson, Derrick E. Fouts, Alan Collmer, and Olaf Schneewind Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12839–12843. PMCID: PMC23122 Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor Yukari C. Manabe, Beatrice J. Saviola, Li Sun, John R. Murphy, and William R. Bishai Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12844–12848. PMCID: PMC23125 Adeno-associated virus (AAV) site-specific integration: Formation of AAV–AAVS1 junctions in an in vitro system Julie Dyall, Paul Szabo, and Kenneth I. Berns Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12849–12854. PMCID: PMC23128 Neurobiology The neuroprotective agent SR 57746A abrogates experimental autoimmune encephalomyelitis and impairs associated blood–brain barrier disruption: Implications for multiple sclerosis treatment Bernard Bourrié, Estelle Bribes, Martine Esclangon, Laurent Garcia, Jean Marchand, Corinne Thomas, Jean-Pierre Maffrand, and Pierre Casellas Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12855–12859. PMCID: PMC23131 Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo Kristin Baer, Christian Essrich, Jack A. Benson, Dietmar Benke, Horst Bluethmann, Jean-Marc Fritschy, and Bernhard Lüscher Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12860–12865. PMCID: PMC23133 MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia Alessandro Alessandrini, Shobu Namura, Michael A. Moskowitz, and Joseph V. Bonventre Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12866–12869. PMCID: PMC23136 Evidence for a protective role of metallothionein-1 in focal cerebral ischemia Menno van Lookeren Campagne, Harold Thibodeaux, Nick van Bruggen, Belinda Cairns, Robert Gerlai, James T. Palmer, Simon P. Williams, and David G. Lowe Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12870–12875. PMCID: PMC23139 Bidirectional, experience-dependent regulation of N-methyl-d-aspartate receptor subunit composition in the rat visual cortex during postnatal development Elizabeth M. Quinlan, Daniel H. Olstein, and Mark F. Bear Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12876–12880. PMCID: PMC23143 Glutamate infused posttraining into the hippocampus or caudate-putamen differentially strengthens place and response learning Mark G. Packard Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12881–12886. PMCID: PMC23146 Survival of reproductive behaviors in estrogen receptor β gene-deficient (βERKO) male and female mice Sonoko Ogawa, Johnny Chan, April E. Chester, Jan-Åke Gustafsson, Kenneth S. Korach, and Donald W. Pfaff Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12887–12892. PMCID: PMC23148 INAUGURAL ARTICLE by a Recently Elected Academy Member: Activity-dependent regulation of synaptic clustering in a hippocampal culture system Ege T. Kavalali, Jürgen Klingauf, and Richard W. Tsien Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12893–12900. PMCID: PMC23151 Vocal imitation in zebra finches is inversely related to model abundance Ofer Tchernichovski, Thierry Lints, Partha P. Mitra, and Fernando Nottebohm Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12901–12904. PMCID: PMC23154 Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice Robert M. Mihalek, Pradeep K. Banerjee, Esa R. Korpi, Joseph J. Quinlan, Leonard L. Firestone, Zhi-Ping Mi, Carl Lagenaur, Verena Tretter, Werner Sieghart, Stephan G. Anagnostaras, Jennifer R. Sage, Michael S. Fanselow, Alessandro Guidotti, Igor Spigelman, Zhiwei Li, Timothy M. DeLorey, Richard W. Olsen, and Gregg E. Homanics Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12905–12910. PMCID: PMC23157 The role of the synthetic enzyme GAD65 in the control of neuronal γ-aminobutyric acid release Ning Tian, Carl Petersen, Shera Kash, Steinunn Baekkeskov, David Copenhagen, and Roger Nicoll Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12911–12916. PMCID: PMC23160 Mechanisms underlying kainate receptor-mediated disinhibition in the hippocampus M. Frerking, C. C. H. Petersen, and R. A. Nicoll Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12917–12922. PMCID: PMC23163 Plant Biology Compromised disease resistance in saponin-deficient plants K. Papadopoulou, R. E. Melton, M. Leggett, M. J. Daniels, and A. E. Osbourn Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12923–12928. PMCID: PMC23166 Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway Ian E. Burbulis and Brenda Winkel-Shirley Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12929–12934. PMCID: PMC23169 Biosynthetic origin of conjugated double bonds: Production of fatty acid components of high-value drying oils in transgenic soybean embryos Edgar B. Cahoon, Thomas J. Carlson, Kevin G. Ripp, Bruce J. Schweiger, George A. Cook, Sarah E. Hall, and Anthony J. Kinney Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12935–12940. PMCID: PMC23170 Genetic ablation of root cap cells in Arabidopsis Ryuji Tsugeki and Nina V. Fedoroff Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12941–12946. PMCID: PMC23173 Proteinase inhibitor-inducing activity of the prohormone prosystemin resides exclusively in the C-terminal systemin domain James E. Dombrowski, Gregory Pearce, and Clarence A. Ryan Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12947–12952. PMCID: PMC23176 Psychology Invariance between subjects of brain wave representations of language Patrick Suppes, Bing Han, Julie Epelboim, and Zhong-Lin Lu Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12953–12958. PMCID: PMC23179 Functional neuroanatomical double dissociation of mnemonic and executive control processes contributing to working memory performance Bradley R. Postle, Jeffrey S. Berger, and Mark D’Esposito Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12959–12964. PMCID: PMC23182 Low-status monkeys “play dumb” when learning in mixed social groups Christine M. Drea and Kim Wallen Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12965–12969. PMCID: PMC23184 Social Sciences Anthropology Low-status monkeys “play dumb” when learning in mixed social groups Christine M. Drea and Kim Wallen Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12965–12969. PMCID: PMC23184 Correction Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12970. PMCID: PMC56178 Corrects: Cheng-Chi Chao, et al. The role of MHC class II molecules in susceptibility to type I diabetes: Identification of peptide epitopes and characterization of the T cell repertoire. Proc Natl Acad Sci U S A. 1999 August 3; 96(16): 9299–9304. |