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Volume 96(22);  October 26, 1999
Commentaries
Long terminal repeat retrotransposons jump between species
Andrew J. Flavell
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12211–12212.
PMCID: PMC34249
Calcium from internal stores modifies dendritic spine shape
Kristen M. Harris
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12213–12215.
PMCID: PMC34250
Cancer prevention and diet: Help from single nucleotide polymorphisms
Bruce N. Ames
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12216–12218.
PMCID: PMC34251
Making sense of polymer-based biosensors
Peter S. Heeger and Alan J. Heeger
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12219–12221.
PMCID: PMC34252
Delineating muscarinic receptor functions
Raul R. Gainetdinov and Marc G. Caron
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12222–12223.
PMCID: PMC34253
Bridging the gap: A family of novel DNA polymerases that replicate faulty DNA
Robert E. Johnson, M. Todd Washington, Satya Prakash, and Louise Prakash
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12224–12226.
PMCID: PMC34254
SNARE proteins mediate lipid bilayer fusion
Jason B. Bock and Richard H. Scheller
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12227–12229.
PMCID: PMC34255
VHL: A very hip ligase
Mike Tyers and Rob Rottapel
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12230–12232.
PMCID: PMC34256
Review
The metabolic implications of intracellular circulation
P. W. Hochachka
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12233–12239.
PMCID: PMC34257
Physical Sciences
Applied Mathematics
Energetic considerations of ciliary beating and the advantage of metachronal coordination
Shay Gueron and Konstantin Levit-Gurevich
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12240–12245.
PMCID: PMC22900
Chemistry
Reptilian chemistry: Characterization of dianeackerone, a secretory product from a crocodile
Authrine Whyte, Zhi-Cai Yang, Kittichoat Tiyanont, Paul J. Weldon, Thomas Eisner, and Jerrold Meinwald
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12246–12250.
PMCID: PMC22901
Reptilian chemistry: Characterization of a family of dianeackerone-related steroidal esters from a crocodile secretion
Zhicai Yang, Authrine Whyte, Athula B. Attygalle, Paul J. Weldon, Thomas Eisner, and Jerrold Meinwald
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12251–12256.
PMCID: PMC22902
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor
Patricia Andrade-Gordon, Bruce E. Maryanoff, Claudia K. Derian, Han-Cheng Zhang, Michael F. Addo, Andrew L. Darrow, Annette J. Eckardt, William J. Hoekstra, David F. McComsey, Donna Oksenberg, Elwood E. Reynolds, Rosemary J. Santulli, Robert M. Scarborough, Charles E. Smith, and Kimberly B. White
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12257–12262.
PMCID: PMC22903
Mathematics
Solution of the pulse width modulation problem using orthogonal polynomials and Korteweg-de Vries equations
D. V. Chudnovsky and G. V. Chudnovsky
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12263–12268.
PMCID: PMC22904
Physics
Pressure-enhanced ortho-para conversion in solid hydrogen up to 58 GPa
Jon H. Eggert, Eran Karmon, Russell J. Hemley, Ho-kwang Mao, and Alexander F. Goncharov
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12269–12272.
PMCID: PMC22905
Statistics
Derived variables for longitudinal studies
D. R. Cox and Nanny Wermuth
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12273–12274.
PMCID: PMC22906
Biological Sciences
Agricultural Sciences
Identification of lumichrome as a Sinorhizobium enhancer of alfalfa root respiration and shoot growth
Donald A. Phillips, Cecillia M. Joseph, Guo-Ping Yang, Esperanza Martínez-Romero, James R. Sanborn, and Hanne Volpin
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12275–12280.
PMCID: PMC22907
Anthropology
Direct radiocarbon dates for Vindija G1 and Velika Pećina Late Pleistocene hominid remains
Fred H. Smith, Erik Trinkaus, Paul B. Pettitt, Ivor Karavanić, and Maja Paunović
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12281–12286.
PMCID: PMC22908
Applied Biological Sciences
From the Cover:
Highly sensitive biological and chemical sensors based on reversible fluorescence quenching in a conjugated polymer
Liaohai Chen, Duncan W. McBranch, Hsing-Lin Wang, Roger Helgeson, Fred Wudl, and David G. Whitten
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12287–12292.
PMCID: PMC22909
DNA packing in stable lipid complexes designed for gene transfer imitates DNA compaction in bacteriophage
M. Schmutz, D. Durand, A. Debin, Y. Palvadeau, A. Etienne, and A. R. Thierry
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12293–12298.
PMCID: PMC22910
Biochemistry
Three metal ions at the active site of the Tetrahymena group I ribozyme
Shu-ou Shan, Aiichiro Yoshida, Sengen Sun, Joseph A. Piccirilli, and Daniel Herschlag
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12299–12304.
PMCID: PMC22911
A structural view of evolutionary divergence
Ben Spiller, Anne Gershenson, Frances H. Arnold, and Raymond C. Stevens
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12305–12310.
PMCID: PMC22912
Targeting a SWI/SNF-related chromatin remodeling complex to the β-globin promoter in erythroid cells
Chang-Hun Lee, Michael R. Murphy, Jong-Soo Lee, and Jay H. Chung
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12311–12315.
PMCID: PMC22913
Assembly of a catalytic unit for RNA microhelix aminoacylation using nonspecific RNA binding domains
Joseph W. Chihade and Paul Schimmel
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12316–12321.
PMCID: PMC22914
Conversion of agonist site to metal-ion chelator site in the β2-adrenergic receptor
Christian E. Elling, Kenneth Thirstrup, Birgitte Holst, and Thue W. Schwartz
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12322–12327.
PMCID: PMC22915
NMR characterization of lignins in Arabidopsis altered in the activity of ferulate 5-hydroxylase
Jane M. Marita, John Ralph, Ronald D. Hatfield, and Clint Chapple
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12328–12332.
PMCID: PMC22916
Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product
Shoko Hirotsu, Yasuko Abe, Kengo Okada, Noriyuki Nagahara, Hiroyuki Hori, Takeshi Nishino, and Toshio Hakoshima
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12333–12338.
PMCID: PMC22917
Purification of ribonucleotide reductase subunits Y1, Y2, Y3, and Y4 from yeast: Y4 plays a key role in diiron cluster assembly
Hiep-Hoa T. Nguyen, Jie Ge, Deborah L. Perlstein, and JoAnne Stubbe
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12339–12344.
PMCID: PMC22918
A protein residing at the subunit interface of the bacterial ribosome
Dmitry E. Agafonov, Vyacheslav A. Kolb, Igor V. Nazimov, and Alexander S. Spirin
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12345–12349.
PMCID: PMC22919
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1
Young Ho Kim, Cheol Yong Choi, and Yongsok Kim
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12350–12355.
PMCID: PMC22920
Yeast HOS3 forms a novel trichostatin A-insensitive homodimer with intrinsic histone deacetylase activity
Andrew A. Carmen, Patrick R. Griffin, Jimmy R. Calaycay, Stephen E. Rundlett, Yuko Suka, and Michael Grunstein
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12356–12361.
PMCID: PMC22921
The protein kinase CK2 is involved in regulation of circadian rhythms in Arabidopsis
Shoji Sugano, Christos Andronis, May S. Ong, Rachel M. Green, and Elaine M. Tobin
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12362–12366.
PMCID: PMC22922
Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe
Kyeong-Yeop Moon, Daochun Kong, Joon-Kyu Lee, Santanu Raychaudhuri, and Jerard Hurwitz
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12367–12372.
PMCID: PMC22923
The Escherichia coli SOS mutagenesis proteins UmuD and UmuD′ interact physically with the replicative DNA polymerase
Mark D. Sutton, Timothy Opperman, and Graham C. Walker
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12373–12378.
PMCID: PMC22924
Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus
Andrea Carfí, Craig A. Smith, Pamela J. Smolak, Jeffrey McGrew, and Don C. Wiley
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12379–12383.
PMCID: PMC22925
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
Derek R. Duckett, S. Maynard Bronstein, Yoichi Taya, and Paul Modrich
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12384–12388.
PMCID: PMC22926
In Azotobacter vinelandii, the E1 subunit of the pyruvate dehydrogenase complex binds fpr promoter region DNA and ferredoxin I
Karin Regnström, Sandrine Sauge-Merle, Kaisheng Chen, and Barbara K. Burgess
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12389–12393.
PMCID: PMC22927
Mobilization of the A-kinase N-myristate through an isoform-specific intermolecular switch
Milind Gangal, Teresa Clifford, Jason Deich, Xiaodong Cheng, Susan S. Taylor, and David A. Johnson
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12394–12399.
PMCID: PMC22929
Isolation of a Chinese hamster ovary cell mutant defective in intramitochondrial transport of phosphatidylserine
Kazuo Emoto, Osamu Kuge, Masahiro Nishijima, and Masato Umeda
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12400–12405.
PMCID: PMC22930
RNase E is required for the maturation of ssrA RNA and normal ssrA RNA peptide-tagging activity
Sue Lin-Chao, Chia-Li Wei, and Yi-Tzu Lin
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12406–12411.
PMCID: PMC22933
Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue
Xianwen Yi, Mark Mroczko, Kelath M. Manoj, Xiaotang Wang, and Lowell P. Hager
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12412–12417.
PMCID: PMC22935
Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity
Ehab M. Khalil, Jacqueline De Angelis, Makoto Ishii, and Philip A. Cole
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12418–12423.
PMCID: PMC22936
Purification and characterization of sortase, the transpeptidase that cleaves surface proteins of Staphylococcus aureus at the LPXTG motif
Hung Ton-That, Gwen Liu, Sarkis K. Mazmanian, Kym F. Faull, and Olaf Schneewind
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12424–12429.
PMCID: PMC22937
Translocation and specific cleavage of bacteriophage T7 DNA in vivo by EcoKI
L. René García and Ian J. Molineux
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12430–12435.
PMCID: PMC22939
From the Cover:
Identification of the von Hippel–Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
Kazuhiro Iwai, Koji Yamanaka, Takumi Kamura, Nagahiro Minato, Ronald C. Conaway, Joan W. Conaway, Richard D. Klausner, and Arnim Pause
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12436–12441.
PMCID: PMC22941
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling
Yin Sun, Xuedong Liu, Elinor Ng-Eaton, Harvey F. Lodish, and Robert A. Weinberg
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12442–12447.
PMCID: PMC22943
Opening of a monomer-monomer interface of the trimeric bacteriophage T4-coded GP45 sliding clamp is required for clamp loading onto DNA
Gary J. Latham, Feng Dong, Paola Pietroni, Jody M. Dozono, Daniel J. Bacheller, and Peter H. von Hippel
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12448–12453.
PMCID: PMC22945
Ku is associated with the telomere in mammals
Hsin-Ling Hsu, David Gilley, Elizabeth H. Blackburn, and David J. Chen
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12454–12458.
PMCID: PMC22947
Rapid treadmilling of brain microtubules free of microtubule-associated proteins in vitro and its suppression by tau
Dulal Panda, Herbert P. Miller, and Leslie Wilson
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12459–12464.
PMCID: PMC22948
The solution structure of the Zα domain of the human RNA editing enzyme ADAR1 reveals a prepositioned binding surface for Z-DNA
Markus Schade, Christopher J. Turner, Ronald Kühne, Peter Schmieder, Ky Lowenhaupt, Alan Herbert, Alexander Rich, and Hartmut Oschkinat
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12465–12470.
PMCID: PMC22950
An optimal Mg2+ concentration for kinetic folding of the Tetrahymena ribozyme
Martha S. Rook, Daniel K. Treiber, and James R. Williamson
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12471–12476.
PMCID: PMC22953
Biophysics
The use of site-directed fluorophore labeling and donor–donor energy migration to investigate solution structure and dynamics in proteins
Fredrik Bergström, Peter Hägglöf, Jan Karolin, Tor Ny, and Lennart B.-Å. Johansson
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12477–12481.
PMCID: PMC22954
Folding protein models with a simple hydrophobic energy function: The fundamental importance of monomer inside/outside segregation
Antônio F. Pereira de Araújo
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12482–12487.
PMCID: PMC22956
Tropomyosin directly modulates actomyosin mechanical performance at the level of a single actin filament
Peter VanBuren, Kimberly A. Palmiter, and David M. Warshaw
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12488–12493.
PMCID: PMC22958
Measures of residue density in protein structures
Franck Baud and Samuel Karlin
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12494–12499.
PMCID: PMC22960
Atom density in protein structures
Samuel Karlin, Zhan-Yang Zhu, and Franck Baud
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12500–12505.
PMCID: PMC22962
Odor space and olfactory processing: Collective algorithms and neural implementation
J. J. Hopfield
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12506–12511.
PMCID: PMC22963
Exploring the origins of topological frustration: Design of a minimally frustrated model of fragment B of protein A
Joan-Emma Shea, José N. Onuchic, and Charles L. Brooks, III
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12512–12517.
PMCID: PMC22965
Self-assembly of fibronectin into fibrillar networks underneath dipalmitoyl phosphatidylcholine monolayers: Role of lipid matrix and tensile forces
Gretchen Baneyx and Viola Vogel
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12518–12523.
PMCID: PMC22966
Structure-based conformational preferences of amino acids
Patrice Koehl and Michael Levitt
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12524–12529.
PMCID: PMC22969
Cell Biology
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor
Patricia Andrade-Gordon, Bruce E. Maryanoff, Claudia K. Derian, Han-Cheng Zhang, Michael F. Addo, Andrew L. Darrow, Annette J. Eckardt, William J. Hoekstra, David F. McComsey, Donna Oksenberg, Elwood E. Reynolds, Rosemary J. Santulli, Robert M. Scarborough, Charles E. Smith, and Kimberly B. White
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12257–12262.
PMCID: PMC22903
Effectors of a developmental mitogen-activated protein kinase cascade revealed by expression signatures of signaling mutants
H. D. Madhani, T. Galitski, E. S. Lander, and G. R. Fink
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12530–12535.
PMCID: PMC22972
A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2
Victor S. Goldmacher, Laura M. Bartle, Anna Skaletskaya, Cheryl A. Dionne, Nancy L. Kedersha, Carol A. Vater, Jia-wen Han, Robert J. Lutz, Shinya Watanabe, Ellen D. Cahir McFarland, Elliott D. Kieff, Edward S. Mocarski, and Thomas Chittenden
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12536–12541.
PMCID: PMC22976
The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein
Heather Morehouse, Robin M. Buratowski, Pamela A. Silver, and Stephen Buratowski
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12542–12547.
PMCID: PMC22979
Casein kinase I[var epsilon] in the Wnt pathway: Regulation of β-catenin function
Chie Sakanaka, Peng Leong, Licen Xu, Stephen D. Harrison, and Lewis T. Williams
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12548–12552.
PMCID: PMC22983
Tumor burden and clonality in multiple intestinal neoplasia mouse/normal mouse aggregation chimeras
Marco R. Novelli, Harpreet Wasan, Ian Rosewell, Julie Bee, Ian P. Tomlinson, Nicholas A. Wright, and Walter F. Bodmer
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12553–12558.
PMCID: PMC22985
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
Yuting Tang, Liaoyuan A. Hu, William E. Miller, Niels Ringstad, Randy A. Hall, Julie A. Pitcher, Pietro DeCamilli, and Robert J. Lefkowitz
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12559–12564.
PMCID: PMC22990
Rapid and efficient fusion of phospholipid vesicles by the α-helical core of a SNARE complex in the absence of an N-terminal regulatory domain
Francesco Parlati, Thomas Weber, James A. McNew, Benedikt Westermann, Thomas H. Söllner, and James E. Rothman
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12565–12570.
PMCID: PMC22992
Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs
Walter Nickel, Thomas Weber, James A. McNew, Francesco Parlati, Thomas H. Söllner, and James E. Rothman
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12571–12576.
PMCID: PMC22994
The active digestion of uniparental chloroplast DNA in a single zygote of Chlamydomonas reinhardtii is revealed by using the optical tweezer
Yoshiki Nishimura, Osami Misumi, Sachihiro Matsunaga, Tetsuya Higashiyama, Akiho Yokota, and Tsuneyoshi Kuroiwa
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12577–12582.
PMCID: PMC22996
Calcium-independent activation of endothelial nitric oxide synthase by ceramide
Junsuke Igarashi, Hemant S. Thatte, Prakash Prabhakar, David E. Golan, and Thomas Michel
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12583–12588.
PMCID: PMC22998
Proteomic definition of normal human luminal and myoepithelial breast cells purified from reduction mammoplasties
Martin J. Page, Bob Amess, R. Reid Townsend, Raj Parekh, Athula Herath, Luc Brusten, Marketa J. Zvelebil, Robert C. Stein, Michael D. Waterfield, Susan C. Davies, and Michael J. O’Hare
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12589–12594.
PMCID: PMC23001
Developmental Biology
Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis
Joerg Heyer, Diana Escalante-Alcalde, Marie Lia, Erwin Boettinger, Winfried Edelmann, Colin L. Stewart, and Raju Kucherlapati
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12595–12600.
PMCID: PMC23005
Developmental exposure to vasopressin increases aggression in adult prairie voles
John M. Stribley and C. Sue Carter
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12601–12604.
PMCID: PMC23008
The STAR protein QKI-6 is a translational repressor
Lisa Saccomanno, Carrie Loushin, Eric Jan, Eric Punkay, Karen Artzt, and Elizabeth B. Goodwin
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12605–12610.
PMCID: PMC23011
Ecology
Self-organized defensive behavior in honeybees
J. Millor, M. Pham-Delegue, J. L. Deneubourg, and S. Camazine
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12611–12615.
PMCID: PMC23012
Evolution
From the Cover:
Two living species of coelacanths?
Mark T. Holder, Mark V. Erdmann, Thomas P. Wilcox, Roy L. Caldwell, and David M. Hillis
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12616–12620.
PMCID: PMC23015
From the Cover:
Evidence for the recent horizontal transfer of long terminal repeat retrotransposon
I. King Jordan, Lilya V. Matyunina, and John F. McDonald
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12621–12625.
PMCID: PMC23018
Macroevolution of insect–plant associations: The relevance of host biogeography to host affiliation
Judith X. Becerra and D. Lawrence Venable
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12626–12631.
PMCID: PMC23020
All males are not created equal: Fertility differences depend on gamete recognition polymorphisms in sea urchins
Stephen R. Palumbi
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12632–12637.
PMCID: PMC23023
Calibrating bacterial evolution
Howard Ochman, Susannah Elwyn, and Nancy A. Moran
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12638–12643.
PMCID: PMC23026
Signaling of need, sibling competition, and the cost of honesty
Rufus A. Johnstone
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12644–12649.
PMCID: PMC23029
Genetics
Profound misregulation of muscle-specific gene expression in facioscapulohumeral muscular dystrophy
Rossella Tupler, Giovanni Perini, Maria Antonietta Pellegrino, and Michael R. Green
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12650–12654.
PMCID: PMC23032
Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation
D. Gachotte, S. E. Sen, J. Eckstein, R. Barbuch, M. Krieger, B. D. Ray, and M. Bard
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12655–12660.
PMCID: PMC23033
Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers
Shannon A. Kuismanen, Mari T. Holmberg, Reijo Salovaara, Pascal Schweizer, Lauri A. Aaltonen, Albert de la Chapelle, Minna Nyström-Lahti, and Päivi Peltomäki
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12661–12666.
PMCID: PMC23037
LFG: An anti-apoptotic gene that provides protection from Fas-mediated cell death
Nikunj V. Somia, Mark J. Schmitt, Douglas E. Vetter, Daniel Van Antwerp, Stephen F. Heinemann, and Inder M. Verma
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12667–12672.
PMCID: PMC23041
A genetic method for dissecting the mechanism of transcriptional activator synergy by identical activators
Robert C. Langdon and Ann Hochschild
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12673–12678.
PMCID: PMC23043
The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components
Bee Na Lee and Elaine A. Elion
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12679–12684.
PMCID: PMC23046
Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred
Alan T. Remaley, Stephan Rust, Marie Rosier, Cathy Knapper, Laurent Naudin, Cyril Broccardo, Katherine M. Peterson, Christine Koch, Isabelle Arnould, Catherine Prades, Nicholas Duverger, Harald Funke, Gerd Assman, Maria Dinger, Michael Dean, Giovanna Chimini, Silvia Santamarina-Fojo, Donald S. Fredrickson, Patrice Denefle, and H. Bryan Brewer, Jr.
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12685–12690.
PMCID: PMC23050
Immunology
Activation changes the spectrum but not the diversity of genes expressed by T cells
T. Kent Teague, David Hildeman, Ross M. Kedl, Tom Mitchell, William Rees, Brian C. Schaefer, Jeremy Bender, John Kappler, and Philippa Marrack
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12691–12696.
PMCID: PMC23052
From the Cover:
BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes simplex virus 1
Mark Suter, Andrew M. Lew, Philipp Grob, Gosse J. Adema, Mathias Ackermann, Ken Shortman, and Cornel Fraefel
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12697–12702.
PMCID: PMC23055
CD8 T cell ignorance or tolerance to islet antigens depends on antigen dose
Christian Kurts, Robyn M. Sutherland, Gayle Davey, Ming Li, Andrew M. Lew, Effrossini Blanas, Francis R. Carbone, Jacques F. A. P. Miller, and William R. Heath
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12703–12707.
PMCID: PMC23058
Humoral response to herpes simplex virus is complement-dependent
Xavier J. Da Costa, Mark A. Brockman, Elisabeth Alicot, Minghe Ma, Michael B. Fischer, Xioaning Zhou, David M. Knipe, and Michael C. Carroll
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12708–12712.
PMCID: PMC23060
RAG2 is regulated differentially in B and T cells by elements 5′ of the promoter
Robert J. Monroe, Feng Chen, Roger Ferrini, Laurie Davidson, and Frederick W. Alt
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12713–12718.
PMCID: PMC23063
Medical Sciences
In vivo inhibition of rat stellate cell activation by soluble transforming growth factor β type II receptor: A potential new therapy for hepatic fibrosis
Jacob George, Dominique Roulot, Victor E. Koteliansky, and D. Montgomery Bissell
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12719–12724.
PMCID: PMC23066
Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein
Melissa Burton, Hiroyuki Nakai, Peter Colosi, Janet Cunningham, Rachel Mitchell, and Linda Couto
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12725–12730.
PMCID: PMC23069
Nrf2 is essential for protection against acute pulmonary injury in mice
Kaimin Chan and Yuet Wai Kan
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12731–12736.
PMCID: PMC23072
Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes
Marc Foretz, Colette Guichard, Pascal Ferré, and Fabienne Foufelle
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12737–12742.
PMCID: PMC23076
Plasmodium falciparum domain mediating adhesion to chondroitin sulfate A: A receptor for human placental infection
Pierre A. Buffet, Benoit Gamain, Christine Scheidig, Dror Baruch, Joseph D. Smith, Rosaura Hernandez-Rivas, Bruno Pouvelle, Shinya Oishi, Nobutaka Fujii, Thierry Fusai, Daniel Parzy, Louis H. Miller, Jürg Gysin, and Artur Scherf
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12743–12748.
PMCID: PMC23079
Dose-response resistance to HIV-1/MuLV pseudotype virus ex vivo in a hairpin ribozyme transgenic mouse model
Michael Andäng, Jorma Hinkula, Graham Hotchkiss, Sten Larsson, Sven Britton, Flossie Wong-Staal, Britta Wahren, and Lars Ährlund-Richter
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12749–12753.
PMCID: PMC23081
In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
Gerard J. Nuovo, Todd W. Plaia, Steven A. Belinsky, Stephen B. Baylin, and James G. Herman
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12754–12759.
PMCID: PMC23084
A mechanism of paraquat toxicity involving nitric oxide synthase
Brian J. Day, Manisha Patel, Lisa Calavetta, Ling-Yi Chang, and Jonathan S. Stamler
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12760–12765.
PMCID: PMC23088
Hepatitis C virus and other Flaviviridae viruses enter cells via low density lipoprotein receptor
Vincent Agnello, György Ábel, Mutasim Elfahal, Glenn B. Knight, and Qing-Xiu Zhang
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12766–12771.
PMCID: PMC23090
Molecular cloning and functional analysis of SUT-1, a sulfate transporter from human high endothelial venules
Jean-Philippe Girard, Espen S. Baekkevold, Jacques Feliu, Per Brandtzaeg, and François Amalric
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12772–12777.
PMCID: PMC23093
Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin
Markus Gerhard, Norbert Lehn, Nina Neumayer, Thomas Borén, Roland Rad, Wolfgang Schepp, Stephan Miehlke, Meinhard Classen, and Christian Prinz
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12778–12783.
PMCID: PMC23096
Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: Role of epsilon protein kinase C
Che-Hong Chen, Mary O. Gray, and Daria Mochly-Rosen
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12784–12789.
PMCID: PMC23099
Steroid disorders in children: Congenital adrenal hyperplasia and apparent mineralocorticoid excess
Maria I. New and Robert C. Wilson
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12790–12797.
PMCID: PMC23101
Sustained in vivo cardiac protection by a rationally designed peptide that causes [var epsilon] protein kinase C translocation
Gerald W. Dorn, II, Miriam C. Souroujon, Tamar Liron, Che-Hong Chen, Mary O. Gray, Hui Zhong Zhou, Michael Csukai, Guangyu Wu, John N. Lorenz, and Daria Mochly-Rosen
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12798–12803.
PMCID: PMC23103
Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia
Xiaoyan Jiang, Angel Lopez, Tessa Holyoake, Allen Eaves, and Connie Eaves
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12804–12809.
PMCID: PMC23105
Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
Christine F. Skibola, Martyn T. Smith, Eleanor Kane, Eve Roman, Sara Rollinson, Raymond A. Cartwright, and Gareth Morgan
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12810–12815.
PMCID: PMC23109
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons
Núria Morral, Wanda O’Neal, Karen Rice, Michele Leland, Johanne Kaplan, Pedro A. Piedra, Heshan Zhou, Robin J. Parks, Rizwan Velji, Estuardo Aguilar-Córdova, Samuel Wadsworth, Frank L. Graham, Stefan Kochanek, K. Dee Carey, and Arthur L. Beaudet
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12816–12821.
PMCID: PMC23112
The inv(16) encodes an acute myeloid leukemia 1 transcriptional corepressor
Bart Lutterbach, Yue Hou, Kristie L. Durst, and Scott W. Hiebert
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12822–12827.
PMCID: PMC23113
Microbiology
A conserved residue in the tip proteins of CS1 and CFA/I pili of enterotoxigenic Escherichia coli that is essential for adherence
Harry Sakellaris, George P. Munson, and June R. Scott
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12828–12832.
PMCID: PMC23117
Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization
Michael Wilson, Joseph DeRisi, Hans-Henrik Kristensen, Paul Imboden, Sangeeta Rane, Patrick O. Brown, and Gary K. Schoolnik
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12833–12838.
PMCID: PMC23119
Reciprocal secretion of proteins by the bacterial type III machines of plant and animal pathogens suggests universal recognition of mRNA targeting signals
Deborah M. Anderson, Derrick E. Fouts, Alan Collmer, and Olaf Schneewind
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12839–12843.
PMCID: PMC23122
Attenuation of virulence in Mycobacterium tuberculosis expressing a constitutively active iron repressor
Yukari C. Manabe, Beatrice J. Saviola, Li Sun, John R. Murphy, and William R. Bishai
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12844–12848.
PMCID: PMC23125
Adeno-associated virus (AAV) site-specific integration: Formation of AAV–AAVS1 junctions in an in vitro system
Julie Dyall, Paul Szabo, and Kenneth I. Berns
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12849–12854.
PMCID: PMC23128
Neurobiology
The neuroprotective agent SR 57746A abrogates experimental autoimmune encephalomyelitis and impairs associated blood–brain barrier disruption: Implications for multiple sclerosis treatment
Bernard Bourrié, Estelle Bribes, Martine Esclangon, Laurent Garcia, Jean Marchand, Corinne Thomas, Jean-Pierre Maffrand, and Pierre Casellas
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12855–12859.
PMCID: PMC23131
Postsynaptic clustering of γ-aminobutyric acid type A receptors by the γ3 subunit in vivo
Kristin Baer, Christian Essrich, Jack A. Benson, Dietmar Benke, Horst Bluethmann, Jean-Marc Fritschy, and Bernhard Lüscher
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12860–12865.
PMCID: PMC23133
MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia
Alessandro Alessandrini, Shobu Namura, Michael A. Moskowitz, and Joseph V. Bonventre
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12866–12869.
PMCID: PMC23136
Evidence for a protective role of metallothionein-1 in focal cerebral ischemia
Menno van Lookeren Campagne, Harold Thibodeaux, Nick van Bruggen, Belinda Cairns, Robert Gerlai, James T. Palmer, Simon P. Williams, and David G. Lowe
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12870–12875.
PMCID: PMC23139
Bidirectional, experience-dependent regulation of N-methyl-d-aspartate receptor subunit composition in the rat visual cortex during postnatal development
Elizabeth M. Quinlan, Daniel H. Olstein, and Mark F. Bear
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12876–12880.
PMCID: PMC23143
Glutamate infused posttraining into the hippocampus or caudate-putamen differentially strengthens place and response learning
Mark G. Packard
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12881–12886.
PMCID: PMC23146
Survival of reproductive behaviors in estrogen receptor β gene-deficient (βERKO) male and female mice
Sonoko Ogawa, Johnny Chan, April E. Chester, Jan-Åke Gustafsson, Kenneth S. Korach, and Donald W. Pfaff
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12887–12892.
PMCID: PMC23148
Activity-dependent regulation of synaptic clustering in a hippocampal culture system
Ege T. Kavalali, Jürgen Klingauf, and Richard W. Tsien
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12893–12900.
PMCID: PMC23151
Vocal imitation in zebra finches is inversely related to model abundance
Ofer Tchernichovski, Thierry Lints, Partha P. Mitra, and Fernando Nottebohm
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12901–12904.
PMCID: PMC23154
Attenuated sensitivity to neuroactive steroids in γ-aminobutyrate type A receptor delta subunit knockout mice
Robert M. Mihalek, Pradeep K. Banerjee, Esa R. Korpi, Joseph J. Quinlan, Leonard L. Firestone, Zhi-Ping Mi, Carl Lagenaur, Verena Tretter, Werner Sieghart, Stephan G. Anagnostaras, Jennifer R. Sage, Michael S. Fanselow, Alessandro Guidotti, Igor Spigelman, Zhiwei Li, Timothy M. DeLorey, Richard W. Olsen, and Gregg E. Homanics
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12905–12910.
PMCID: PMC23157
The role of the synthetic enzyme GAD65 in the control of neuronal γ-aminobutyric acid release
Ning Tian, Carl Petersen, Shera Kash, Steinunn Baekkeskov, David Copenhagen, and Roger Nicoll
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12911–12916.
PMCID: PMC23160
Mechanisms underlying kainate receptor-mediated disinhibition in the hippocampus
M. Frerking, C. C. H. Petersen, and R. A. Nicoll
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12917–12922.
PMCID: PMC23163
Plant Biology
Compromised disease resistance in saponin-deficient plants
K. Papadopoulou, R. E. Melton, M. Leggett, M. J. Daniels, and A. E. Osbourn
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12923–12928.
PMCID: PMC23166
Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway
Ian E. Burbulis and Brenda Winkel-Shirley
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12929–12934.
PMCID: PMC23169
Biosynthetic origin of conjugated double bonds: Production of fatty acid components of high-value drying oils in transgenic soybean embryos
Edgar B. Cahoon, Thomas J. Carlson, Kevin G. Ripp, Bruce J. Schweiger, George A. Cook, Sarah E. Hall, and Anthony J. Kinney
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12935–12940.
PMCID: PMC23170
Genetic ablation of root cap cells in Arabidopsis
Ryuji Tsugeki and Nina V. Fedoroff
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12941–12946.
PMCID: PMC23173
Proteinase inhibitor-inducing activity of the prohormone prosystemin resides exclusively in the C-terminal systemin domain
James E. Dombrowski, Gregory Pearce, and Clarence A. Ryan
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12947–12952.
PMCID: PMC23176
Psychology
Invariance between subjects of brain wave representations of language
Patrick Suppes, Bing Han, Julie Epelboim, and Zhong-Lin Lu
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12953–12958.
PMCID: PMC23179
Functional neuroanatomical double dissociation of mnemonic and executive control processes contributing to working memory performance
Bradley R. Postle, Jeffrey S. Berger, and Mark D’Esposito
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12959–12964.
PMCID: PMC23182
Low-status monkeys “play dumb” when learning in mixed social groups
Christine M. Drea and Kim Wallen
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12965–12969.
PMCID: PMC23184
Social Sciences
Anthropology
Low-status monkeys “play dumb” when learning in mixed social groups
Christine M. Drea and Kim Wallen
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12965–12969.
PMCID: PMC23184
Correction
Proc Natl Acad Sci U S A. 1999 October 26; 96(22): 12970.
PMCID: PMC56178
Corrects: Cheng-Chi Chao, et al. The role of MHC class II molecules in susceptibility to type I diabetes: Identification of peptide epitopes and characterization of the T cell repertoire. Proc Natl Acad Sci U S A. 1999 August 3; 96(16): 9299–9304.
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