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Found 719 studies with search of: "Methotrexate"
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Rank Status Study
1 Active, not recruiting A Study of the Safety and Efficacy of Intravenous CNTO 148 (Golimumab) in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy
Condition: Rheumatoid Arthritis
Interventions: Biological: golimumab; methotrexate;   Biological: golimumab; placebo;   Biological: golimumab; methotrexate;   Biological: golimumab; placebo;   Drug: placebo; methotrexate;   Biological: golimumab; methotrexate
2 Active, not recruiting Dose Response and Safety Study of Topical Methotrexate for the Treatment of Fingernail Psoriasis
Condition: Fingernail Psoriasis
Interventions: Drug: Methotrexate;   Drug: Methotrexate;   Drug: Methotrexate
3 Completed Treatment of Early RA: Minocycline in Combination With Methotrexate vs Methotrexate Alone
Condition: Rheumatoid Arthritis
Interventions: Drug: Combination of Minocycline and MTX or MTX alone;   Drug: methotrexate
4 Active, not recruiting A Study of the Safety and Efficacy of Golimumab in Subjects With Rheumatoid Arthritis That Are Methotrexate-Naive
Condition: Rheumatoid Arthritis
Interventions: Biological: golimumab;   Drug: placebo; methotrexate;   Drug: golimumab; methotrexate;   Biological: Golimumab
5 Completed Two-Dose Methotrexate for Ectopic Pregnancy
Condition: Ectopic Pregnancy
Intervention: Drug: Methotrexate
6 Active, not recruiting METhotrexate Therapy Effects in the Physical Capacity of Patients With ISchemic Heart Failure (METIS Trial)
Conditions: Heart Failure;   Myocardial Ischemia
Interventions: Drug: Methotrexate;   Drug: Placebo
7 Completed Abatacept and Infliximab in Combination With Methotrexate in Subjects With Rheumatoid Arthritis
Condition: Rheumatoid Arthritis
Interventions: Drug: Abatacept + Methotrexate;   Drug: Infliximab + Methotrexate;   Drug: Placebo + Methotrexate
8 Completed A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study
Condition: Rheumatoid Arthritis
Interventions: Drug: Infliximab, methylprednisolone, methotrexate;   Drug: Methotrexate;   Drug: Methotrexate + Methylprednisolone;   Drug: Methotrexate + Infliximab
9 Completed Remicade Study in Psoriatic Arthritis Patients Of Methotrexate-Naïve Disease (RESPOND) (Study P04422AM1)(COMPLETED)
Condition: Arthritis, Psoriatic
Interventions: Drug: Infliximab + methotrexate;   Drug: Methotrexate
10 Recruiting Dose Dense Adjuvant CMF (Cyclophosphamide, Methotrexate, Fluorouracil) at 14 and 10-11 Day Intervals for Women With Early Stage Breast Cancer
Condition: Breast Cancer
Interventions: Drug: cyclophosphamide, methotrexate, fluorouracil, PEG-filgrastim;   Drug: cyclophosphamide, methotrexate, fluorouracil, PEG-filgrastim
11 Recruiting Methotrexate and Temozolomide Versus Methotrexate, Procarbazine, Vincristine and Cytarabine
Condition: Lymphoma
Interventions: Drug: Methotrexate and temozolomide;   Drug: Methotrexate , procarbazine ,vincristine ,cytarabine
12 Not yet recruiting Assessment of Safety and Pharmacokinetics of a Low Dose of Methotrexate in Healthy Adult Male Kenyan Volunteers
Condition: Malaria
Intervention: Drug: Methotrexate
13 Recruiting Study Evaluating Efficacy / Safety of Etanercept + Methotrexate Compared to Usual Treatment in Moderate Rheumatoid Arthritis (RA) Subjects
Condition: Rheumatoid Arthritis
Interventions: Drug: etanercept (EnbrelTM);   Drug: methotrexate;   Drug: disease-modifying anti-rheumatic drug (DMARDs) (Methotrexate, sulfasalazine, hydroxychloroquine, leflunomide, cyclosporine A and gold)
14 Recruiting Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma
Conditions: Lymphoblastic Leukemia;   Lymphoblastic Lymphoma
Interventions: Drug: Daunorubicin;   Drug: Vincristine;   Drug: PEG-asparaginase;   Drug: Intrathecal Methotrexate;   Drug: Cyclophosphamide;   Drug: Cytarabine;   Drug: Mercaptopurine;   Drug: Methotrexate;   Drug: Doxorubicin;   Drug: Thioguanine
15 Recruiting Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy
Condition: Rheumatoid Arthritis
Interventions: Drug: E-551;   Drug: methotrexate;   Drug: S-551;   Drug: H-551;   Drug: methotrexate
16 Recruiting Open-Label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Conditions: Osteosarcoma;   Leukemia;   Lymphoma
Interventions: Drug: glucarpidase, high-dose methotrexate, leucovorin;   Drug: high-dose methotrexate, leucovorin
17 Completed The Effects of Infliximab Versus Methotrexate in the Treatment of Moderate to Severe Psoriasis (Study P04271AM2)(COMPLETED)
Condition: Psoriasis
Interventions: Drug: infliximab;   Drug: methotrexate
18 Completed Efficacy and Safety of TAK-783 in Subjects With Rheumatoid Arthritis
Condition: Arthritis, Rheumatoid
Interventions: Drug: TAK-783 and methotrexate;   Drug: Methotrexate
19 Completed Safety and Efficacy of TAK-715 in Subjects With Rheumatoid Arthritis
Condition: Arthritis, Rheumatoid
Interventions: Drug: TAK-715 and methotrexate;   Drug: TAK-715 and methotrexate;   Drug: TAK-715 and methotrexate;   Drug: Methotrexate
20 Recruiting Methotrexate, Vinblastine, Doxorubicin and Cisplatin (MVAC) Followed by Gemcitabine Plus Cisplatin (GEM+CDDP) in Locally Advanced or Metastatic Bladder Cancer
Condition: Bladder Cancer
Interventions: Drug: Methotrexate;   Drug: Vinblastine;   Drug: Doxorubicin;   Drug: Cisplatin;   Drug: Cisplatin;   Drug: Gemcitabine

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