Thakur A, Sharma V, Mandal A; International Conference on AIDS.
Int Conf AIDS. 1994 Aug 7-12; 10: 164 (abstract no. PB0668).
G.B. Pant Hospital-N.D., Delhi, India.
OBJECTIVE: To find out prevalence of tuberculosis in HIV infected individuals. METHOD: Antibodies to mycobacterial antigen A60 were measured in 126 HIV infected individuals by employing an immune enzymatic test system. RESULTS: Thirty three (26%) serum samples demonstrated 'significant' (200 units/ml and above) antimycobacterial IgG antibodies by this method. A direct correlation was observed with the antibody concentration and the clinico-radiological and bacteriological evidence of tuberculosis of these individuals. Comparison of antibody titre with the spectrum of HIV infection revealed that asymptomatic individuals. CONCLUSION: It is concluded that though conventional bacteriologic studies are still the 'gold standerd' for establishing the diagnosis of tuberculosis. This serological test holds good promise for preliminary diagnosis of mycobacteriesis in HIV infected persons.
Publication Types:
Keywords:
- AIDS Vaccines
- Acquired Immunodeficiency Syndrome
- Antibodies
- Antigens
- Antigens, Bacterial
- HIV Antigens
- HIV Core Protein p24
- HIV Infections
- HIV Seropositivity
- Immunoglobulins
- Serologic Tests
- Tuberculosis
- immunology
Other ID:
UI: 102210109
From Meeting Abstracts