| | This journal provides immediate access to some articles. QnAs QnAs with Karl Mahlburg Regina Nuzzo PMCID: PMC1564270 This Week in PNAS Proc Natl Acad Sci U S A. 2006 September 12; 103(37): 13561–13562. doi: 10.1073/iti3706103.PMCID: PMC1564242 Commentaries Absolute brain size: Did we throw the baby out with the bathwater? Lori Marino PMCID: PMC1564247 A malleable catalyst dominates the metabolism of drugs F. Peter Guengerich PMCID: PMC1564253 Revisiting the photochemistry of solar UVA in human skin David Mitchell PMCID: PMC1564261 Profile Profile of Svante Pääbo Nick Zagorski PMCID: PMC1564240 Physical Sciences Applied Physical Sciences DNA-mediated anisotropic mechanical reinforcement of a virus C. Carrasco, A. Carreira, I. A. T. Schaap, P. A. Serena, J. Gómez-Herrero, M. G. Mateu, and P. J. de Pablo PMCID: PMC1564217 Chemistry Stable four-π-electron, four-membered heterocyclic cations and carbenes Yutaka Ishida, Bruno Donnadieu, and Guy Bertrand PMCID: PMC1564229 Geology INAUGURAL ARTICLE by a Recently Elected Academy Member: Climatically driven emissions of hydrocarbons from marine sediments during deglaciation T. M. Hill, J. P. Kennett, D. L. Valentine, Z. Yang, C. M. Reddy, R. K. Nelson, R. J. Behl, C. Robert, and L. Beaufort PMCID: PMC1564264 Amber from western Amazonia reveals Neotropical diversity during the middle Miocene Pierre-Olivier Antoine, Dario De Franceschi, John J. Flynn, André Nel, Patrice Baby, Mouloud Benammi, Ysabel Calderón, Nicolas Espurt, Anjali Goswami, and Rodolfo Salas-Gismondi PMCID: PMC1564219 Estimating the diversity of dinosaurs Steve C. Wang and Peter Dodson PMCID: PMC1564218 Physics Swimming efficiency of bacterium Escherichia coli Suddhashil Chattopadhyay, Radu Moldovan, Chuck Yeung, and X. L. Wu PMCID: PMC1564254 Realization of a four-step molecular switch in scanning tunneling microscope manipulation of single chlorophyll-a molecules Violeta Iancu and Saw-Wai Hla PMCID: PMC1560088 Biological Sciences Anthropology From the Cover:
Evolution of increased glia–neuron ratios in the human frontal cortex Chet C. Sherwood, Cheryl D. Stimpson, Mary Ann Raghanti, Derek E. Wildman, Monica Uddin, Lawrence I. Grossman, Morris Goodman, John C. Redmond, Christopher J. Bonar, Joseph M. Erwin, and Patrick R. Hof PMCID: PMC1564260 Applied Biological Sciences Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells Juan P. Liuzzi, Fikret Aydemir, Hyeyoung Nam, Mitchell D. Knutson, and Robert J. Cousins PMCID: PMC1564235 A microrotary motor powered by bacteria Yuichi Hiratsuka, Makoto Miyata, Tetsuya Tada, and Taro Q. P. Uyeda PMCID: PMC1564248 Rats produced by interspecies spermatogonial transplantation in mice and in vitro microinsemination Takashi Shinohara, Megumi Kato, Masanori Takehashi, Jiyoung Lee, Shinichiro Chuma, Norio Nakatsuji, Mito Kanatsu-Shinohara, and Masumi Hirabayashi PMCID: PMC1564227 Accurately quantifying low-abundant targets amid similar sequences by revealing hidden correlations in oligonucleotide microarray data Luisa A. Marcelino, Vadim Backman, Andres Donaldson, Claudia Steadman, Janelle R. Thompson, Sarah Pacocha Preheim, Cynthia Lien, Eelin Lim, Daniele Veneziano, and Martin F. Polz PMCID: PMC1559406 Biochemistry Engineering RNA sequence specificity of Pumilio repeats Cheom-Gil Cheong and Traci M. Tanaka Hall PMCID: PMC1564246 Structure of an RNA switch that enforces stringent retroviral genomic RNA dimerization Christopher S. Badorrek, Costin M. Gherghe, and Kevin M. Weeks PMCID: PMC1564256 Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors Kara R. Schmelzer, Bora Inceoglu, Lukas Kubala, In-Hae Kim, Steven L. Jinks, Jason P. Eiserich, and Bruce D. Hammock PMCID: PMC1564210 Purification and molecular cloning of a DNA ADP-ribosylating protein, CARP-1, from the edible clam Meretrix lamarckii Tsuyoshi Nakano, Yuko Matsushima-Hibiya, Masafumi Yamamoto, Shigeki Enomoto, Yasuko Matsumoto, Yukari Totsuka, Masahiko Watanabe, Takashi Sugimura, and Keiji Wakabayashi PMCID: PMC1564245 Helix-packing motifs in membrane proteins R. F. S. Walters and W. F. DeGrado PMCID: PMC1564267 Biosynthesis of mycobacterial lipoarabinomannan: Role of a branching mannosyltransferase Devinder Kaur, Stefan Berg, Premkumar Dinadayala, Brigitte Gicquel, Delphi Chatterjee, Michael R. McNeil, Varalakshmi D. Vissa, Dean C. Crick, Mary Jackson, and Patrick J. Brennan PMCID: PMC1557798 Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome Berthold Wilden, Andreas Savelsbergh, Marina V. Rodnina, and Wolfgang Wintermeyer PMCID: PMC1564220 NikR–operator complex structure and the mechanism of repressor activation by metal ions Eric R. Schreiter, Sheila C. Wang, Deborah B. Zamble, and Catherine L. Drennan PMCID: PMC1564233 From the Cover:
Structural basis for ligand promiscuity in cytochrome P450 3A4 Marika Ekroos and Tove Sjögren PMCID: PMC1564212 Intersubunit signaling in glutamate-1-semialdehyde-aminomutase J. Stetefeld, M. Jenny, and P. Burkhard PMCID: PMC1564225 Phosphorylation of actin Tyr-53 inhibits filament nucleation and elongation and destabilizes filaments Xiong Liu, Shi Shu, Myoung-Soon S. Hong, Rodney L. Levine, and Edward D. Korn PMCID: PMC1557634 Inhibition of a spliceosome turnover pathway suppresses splicing defects Shatakshi Pandit, Bert Lynn, and Brian C. Rymond PMCID: PMC1564266 Biophysics DNA-mediated anisotropic mechanical reinforcement of a virus C. Carrasco, A. Carreira, I. A. T. Schaap, P. A. Serena, J. Gómez-Herrero, M. G. Mateu, and P. J. de Pablo PMCID: PMC1564217 Swimming efficiency of bacterium Escherichia coli Suddhashil Chattopadhyay, Radu Moldovan, Chuck Yeung, and X. L. Wu PMCID: PMC1564254 Realization of a four-step molecular switch in scanning tunneling microscope manipulation of single chlorophyll-a molecules Violeta Iancu and Saw-Wai Hla PMCID: PMC1560088 Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics Jörg Zimmermann, Erin L. Oakman, Ian F. Thorpe, Xinghua Shi, Paul Abbyad, Charles L. Brooks, III, Steven G. Boxer, and Floyd E. Romesberg PMCID: PMC1564241 Chemistry New building blocks in the 2/1 crystalline approximant of a Bergman-type icosahedral quasicrystal Qisheng Lin and John D. Corbett PMCID: PMC1564238 Developmental Biology Molecular characterization of embryonic gonads by gene expression profiling in Drosophila melanogaster Shuji Shigenobu, Yu Kitadate, Chiyo Noda, and Satoru Kobayashi PMCID: PMC1559405 Control of growth and positional information by the graded vestigial expression pattern in the wing of Drosophila melanogaster L. A. Baena-Lopez and A. García-Bellido PMCID: PMC1564234 Ecology Diverse responses of phenology to global changes in a grassland ecosystem Elsa E. Cleland, Nona R. Chiariello, Scott R. Loarie, Harold A. Mooney, and Christopher B. Field PMCID: PMC1560087 Foraging biology predicts food web complexity Andrew P. Beckerman, Owen L. Petchey, and Philip H. Warren PMCID: PMC1560085 Evolution Amber from western Amazonia reveals Neotropical diversity during the middle Miocene Pierre-Olivier Antoine, Dario De Franceschi, John J. Flynn, André Nel, Patrice Baby, Mouloud Benammi, Ysabel Calderón, Nicolas Espurt, Anjali Goswami, and Rodolfo Salas-Gismondi PMCID: PMC1564219 Estimating the diversity of dinosaurs Steve C. Wang and Peter Dodson PMCID: PMC1564218 Chiral-selective aminoacylation of an RNA minihelix: Mechanistic features and chiral suppression Koji Tamura and Paul R. Schimmel PMCID: PMC1564265 Parallel genetic origins of pelvic reduction in vertebrates Michael D. Shapiro, Michael A. Bell, and David M. Kingsley PMCID: PMC1564237 Genetics INAUGURAL ARTICLE by a Recently Elected Academy Member: Patterns of nucleotide misincorporations during enzymatic amplification and direct large-scale sequencing of ancient DNA M. Stiller, R. E. Green, M. Ronan, J. F. Simons, L. Du, W. He, M. Egholm, J. M. Rothberg, S. G. Keates, N. D. Ovodov, E. E. Antipina, G. F. Baryshnikov, Y. V. Kuzmin, A. A. Vasilevski, G. E. Wuenschell, J. Termini, M. Hofreiter, V. Jaenicke-Després, and S. Pääbo PMCID: PMC1564221 A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression Kum-Joo Shin, Estelle A. Wall, Joelle R. Zavzavadjian, Leah A. Santat, Jamie Liu, Jong-Ik Hwang, Robert Rebres, Tamara Roach, William Seaman, Melvin I. Simon, and Iain D. C. Fraser PMCID: PMC1557799 From the Cover:
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation Stéphane Mouret, Caroline Baudouin, Marie Charveron, Alain Favier, Jean Cadet, and Thierry Douki PMCID: PMC1564232 Yeast G1 DNA damage checkpoint regulation by H2A phosphorylation is independent of chromatin remodeling Ali Javaheri, Robert Wysocki, Olivier Jobin-Robitaille, Mohammed Altaf, Jacques Côté, and Stephen J. Kron PMCID: PMC1564209 Immunology LPS-induced TNF-α factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways Xiaoren Tang, Daniel Metzger, Susan Leeman, and Salomon Amar PMCID: PMC1560089 Hmgb3 regulates the balance between hematopoietic stem cell self-renewal and differentiation Michael J. Nemeth, Martha R. Kirby, and David M. Bodine PMCID: PMC1564268 Testing gene function early in the B cell lineage in mb1-cre mice E. Hobeika, S. Thiemann, B. Storch, H. Jumaa, P. J. Nielsen, R. Pelanda, and M. Reth PMCID: PMC1564216 Medical Sciences Nonimmune immunoglobulin binding and multiple adhesion characterize Plasmodium falciparum-infected erythrocytes of placental origin Niloofar Rasti, Fatuma Namusoke, Arnaud Chêne, Qijun Chen, Trine Staalsoe, Mo-Quen Klinkert, Florence Mirembe, Fred Kironde, and Mats Wahlgren PMCID: PMC1564255 Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor Weijing Cai, John C. He, Li Zhu, Changyong Lu, and Helen Vlassara PMCID: PMC1564251 Pregnane X receptor (PXR) activation: A mechanism for neuroprotection in a mouse model of Niemann–Pick C disease S. Joshua Langmade, Sarah E. Gale, Andrey Frolov, Ikuko Mohri, Kinuko Suzuki, Synthia H. Mellon, Steven U. Walkley, Douglas F. Covey, Jean E. Schaffer, and Daniel S. Ory PMCID: PMC1564205 The iminosugar isofagomine increases the activity of N370S mutant acid β-glucosidase in Gaucher fibroblasts by several mechanisms Richard A. Steet, Stephen Chung, Brandon Wustman, Allan Powe, Hung Do, and Stuart A. Kornfeld PMCID: PMC1564243 Effective cell and gene therapy in a murine model of Gaucher disease Ida Berglin Enquist, Eva Nilsson, Andreas Ooka, Jan-Eric Månsson, Karin Olsson, Mats Ehinger, Roscoe O. Brady, Johan Richter, and Stefan Karlsson PMCID: PMC1564262 An aged host promotes the evolution of avirulent coxsackievirus into a virulent strain Raina T. Gay, Sarah Belisle, Melinda A. Beck, and Simin Nikbin Meydani PMCID: PMC1564236 Microbiology Host defenses against Staphylococcus aureus infection require recognition of bacterial lipoproteins Juliane Bubeck Wardenburg, Wade A. Williams, and Dominique Missiakas PMCID: PMC1564215 Leishmania disease development depends on the presence of apoptotic promastigotes in the virulent inoculum Ger van Zandbergen, Annalena Bollinger, Alexander Wenzel, Shaden Kamhawi, Reinhard Voll, Matthias Klinger, Antje Müller, Christoph Hölscher, Martin Herrmann, David Sacks, Werner Solbach, and Tamás Laskay PMCID: PMC1564231 Neuroscience From the Cover:
A Drosophila model for age-associated changes in sleep:wake cycles Kyunghee Koh, Joshua M. Evans, Joan C. Hendricks, and Amita Sehgal PMCID: PMC1564207 Consistent resting-state networks across healthy subjects J. S. Damoiseaux, S. A. R. B. Rombouts, F. Barkhof, P. Scheltens, C. J. Stam, S. M. Smith, and C. F. Beckmann PMCID: PMC1564249 Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6 Mallorie Poët, Uwe Kornak, Michaela Schweizer, Anselm A. Zdebik, Olaf Scheel, Sabine Hoelter, Wolfgang Wurst, Anja Schmitt, Jens C. Fuhrmann, Rosa Planells-Cases, Sara E. Mole, Christian A. Hübner, and Thomas J. Jentsch PMCID: PMC1564226 Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials Alberto Ferri, Mauro Cozzolino, Claudia Crosio, Monica Nencini, Arianna Casciati, Edith Butler Gralla, Giuseppe Rotilio, Joan Selverstone Valentine, and Maria Teresa Carrì PMCID: PMC1557633 Pharmacology Therapeutic potential of histamine H3 receptor agonist for the treatment of obesity and diabetes mellitus Ryo Yoshimoto, Yasuhisa Miyamoto, Ken Shimamura, Akane Ishihara, Kazuhiko Takahashi, Hidehito Kotani, Airu S. Chen, Howard Y. Chen, Douglas J. MacNeil, Akio Kanatani, and Shigeru Tokita PMCID: PMC1560086 Evaluation of disulfide reduction during receptor-mediated endocytosis by using FRET imaging Jun Yang, Hongtao Chen, Iontcho R. Vlahov, Ji-Xin Cheng, and Philip S. Low PMCID: PMC1564263 Physiology Faithful replication of foraging techniques along cultural transmission chains by chimpanzees and children Victoria Horner, Andrew Whiten, Emma Flynn, and Frans B. M. de Waal PMCID: PMC1564214 Psychology Anterior cingulate cortex activity can be independent of response conflict in Stroop-like tasks Ardi Roelofs, Miranda van Turennout, and Michael G. H. Coles PMCID: PMC1564252 Sustainability Science From the Cover:
Wild bees enhance honey bees’ pollination of hybrid sunflower Sarah S. Greenleaf and Claire Kremen PMCID: PMC1564230 Corrections Correction for Abu-Hamad et al., The expression level of the voltage-dependent anion channel controls life and death of the cell PMCID: PMC1564244 Corrects: Salah Abu-Hamad, et al. The expression level of the voltage-dependent anion channel controls life and death of the cell. Proc Natl Acad Sci U S A. 2006 April 11; 103(15): 5787–5792. Correction for Onishi et al., Toward understanding actin activation of myosin ATPase: The role of myosin surface loops PMCID: PMC1564224 Corrects: Hirofumi Onishi, et al. Toward understanding actin activation of myosin ATPase: The role of myosin surface loops. Proc Natl Acad Sci U S A. 2006 April 18; 103(16): 6136–6141. Correction for Flomenbom et al., Utilizing the information content in two-state trajectories PMCID: PMC1564259 Corrects: Ophir Flomenbom, et al. Utilizing the information content in two-state trajectories. Proc Natl Acad Sci U S A. 2006 July 18; 103(29): 10907–10910. Correction for Zaman et al., Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis PMCID: PMC1564228 Corrects: Muhammad H. Zaman, et al. Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. Proc Natl Acad Sci U S A. 2006 July 18; 103(29): 10889–10894. |
