| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14879–14880. doi: 10.1073/iti3807104.PMCID: PMC1986578 Commentaries Targeted cleavage: Tuneable cis-cleaving ribozymes John J. Rossi Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14881–14882. Published online 2007 September 12. doi: 10.1073/pnas.0707141104.PMCID: PMC1986579 Water pulls the strings in hydrophobic polymer collapse Gerhard Hummer Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14883–14884. Published online 2007 September 12. doi: 10.1073/pnas.0706633104.PMCID: PMC1986580 Coupling of predation intensity and global diversity over geologic time Steven M. Holland Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14885–14886. Published online 2007 September 12. doi: 10.1073/pnas.0707409104.PMCID: PMC1986581 Sweet taste signaling in the gut Anthony Sclafani Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14887–14888. Published online 2007 September 12. doi: 10.1073/pnas.0707410104.PMCID: PMC1986582 Physical Sciences Applied Mathematics On the trend, detrending, and variability of nonlinear and nonstationary time series Zhaohua Wu, Norden E. Huang, Steven R. Long, and Chung-Kang Peng Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14889–14894. Published online 2007 September 10. doi: 10.1073/pnas.0701020104.PMCID: PMC1986583 Chemistry From the Cover: Energetics of water permeation through fullerene membrane Hiroyuki Isobe, Tatsuya Homma, and Eiichi Nakamura Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14895–14898. Published online 2007 September 10. doi: 10.1073/pnas.0705010104.PMCID: PMC1975687 A proposed signaling motif for nuclear import in mRNA processing via the formation of arginine claw Donald Hamelberg, Tongye Shen, and J. Andrew McCammon Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14947–14951. Published online 2007 September 6. doi: 10.1073/pnas.0703151104.PMCID: PMC1968059 Geology Biosynthesis of 2-methylbacteriohopanepolyols by an anoxygenic phototroph Sky E. Rashby, Alex L. Sessions, Roger E. Summons, and Dianne K. Newman Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15099–15104. Published online 2007 September 11. doi: 10.1073/pnas.0704912104.PMCID: PMC1986619 Physics Generalization of distance to higher dimensional objects Steven S. Plotkin Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14899–14904. Published online 2007 September 11. doi: 10.1073/pnas.0607833104.PMCID: PMC1986585 Biological Sciences Biochemistry A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment Jacob Bauer, Guangxin Xing, Haruhiko Yagi, Jane M. Sayer, Donald M. Jerina, and Hong Ling Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14905–14910. Published online 2007 September 11. doi: 10.1073/pnas.0700717104.PMCID: PMC1986586 Interaction of signal-recognition particle 54 GTPase domain and signal-recognition particle RNA in the free signal-recognition particle Tobias Hainzl, Shenghua Huang, and A. Elisabeth Sauer-Eriksson Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14911–14916. Published online 2007 September 10. doi: 10.1073/pnas.0702467104.PMCID: PMC1986587 TRRAP and GCN5 are used by c-Myc to activate RNA polymerase III transcription Niall S. Kenneth, Ben A. Ramsbottom, Natividad Gomez-Roman, Lynne Marshall, Philip A. Cole, and Robert J. White Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14917–14922. Published online 2007 September 11. doi: 10.1073/pnas.0702909104.PMCID: PMC1986588 Structural insights into the Slit-Robo complex Cecile Morlot, Nicole M. Thielens, Raimond B. G. Ravelli, Wieger Hemrika, Roland A. Romijn, Piet Gros, Stephen Cusack, and Andrew A. McCarthy Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14923–14928. Published online 2007 September 11. doi: 10.1073/pnas.0705310104.PMCID: PMC1975871 Tipin is required for stalled replication forks to resume DNA replication after removal of aphidicolin in Xenopus egg extracts Alessia Errico, Vincenzo Costanzo, and Tim Hunt Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14929–14934. Published online 2007 September 10. doi: 10.1073/pnas.0706347104.PMCID: PMC1975688 From the Cover: Targeting the absence: Homozygous DNA deletions as immutable signposts for cancer therapy Alexander Varshavsky Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14935–14940. Published online 2007 September 10. doi: 10.1073/pnas.0706546104.PMCID: PMC1986591 Getting specificity from simplicity in putative proteins from the prebiotic Earth Jaime López de la Osa, David A. Bateman, Sylvia Ho, Carlos González, Avijit Chakrabartty, and Douglas V. Laurents Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14941–14946. Published online 2007 September 12. doi: 10.1073/pnas.0706876104.PMCID: PMC1986592 Biophysics Generalization of distance to higher dimensional objects Steven S. Plotkin Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14899–14904. Published online 2007 September 11. doi: 10.1073/pnas.0607833104.PMCID: PMC1986585 A proposed signaling motif for nuclear import in mRNA processing via the formation of arginine claw Donald Hamelberg, Tongye Shen, and J. Andrew McCammon Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14947–14951. Published online 2007 September 6. doi: 10.1073/pnas.0703151104.PMCID: PMC1968059 Robust protein–protein interactions in crowded cellular environments Eric J. Deeds, Orr Ashenberg, Jaline Gerardin, and Eugene I. Shakhnovich Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14952–14957. Published online 2007 September 11. doi: 10.1073/pnas.0702766104.PMCID: PMC1986594 Analysis of ryanodine receptor clusters in rat and human cardiac myocytes Christian Soeller, David Crossman, Ray Gilbert, and Mark B. Cannell Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14958–14963. Published online 2007 September 11. doi: 10.1073/pnas.0703016104.PMCID: PMC1986595 Cell Biology Ribonucleoprotein-masked nicks at 50-kbp intervals in the eukaryotic genomic DNA Lóránt Székvölgyi, Zsuzsa Rákosy, Bálint L. Bálint, Endre Kókai, László Imre, György Vereb, Zsolt Bacsó, Katalin Goda, Sándor Varga, Margit Balázs, Viktor Dombrádi, László Nagy, and Gábor Szabó Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14964–14969. Published online 2007 September 11. doi: 10.1073/pnas.0702269104.PMCID: PMC1986596 Maintenance of imprinting and nuclear architecture in cycling cells Kathrin Teller, Irina Solovei, Karin Buiting, Bernhard Horsthemke, and Thomas Cremer Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14970–14975. Published online 2007 September 11. doi: 10.1073/pnas.0704285104.PMCID: PMC1986597 The Rho GTPase-activating proteins RGA-3 and RGA-4 are required to set the initial size of PAR domains in Caenorhabditis elegans one-cell embryos Stephanie Schonegg, Alexandru T. Constantinescu, Carsten Hoege, and Anthony A. Hyman Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14976–14981. Published online 2007 September 11. doi: 10.1073/pnas.0706941104.PMCID: PMC1986598 Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells Costas A. Lyssiotis, John Walker, Chunlei Wu, Toru Kondo, Peter G. Schultz, and Xu Wu Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14982–14987. Published online 2007 September 12. doi: 10.1073/pnas.0707044104.PMCID: PMC1986599 Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1 Erna Magnúsdóttir, Sergey Kalachikov, Koji Mizukoshi, David Savitsky, Akemi Ishida-Yamamoto, Andrey A. Panteleyev, and Kathryn Calame Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14988–14993. Published online 2007 September 10. doi: 10.1073/pnas.0707323104.PMCID: PMC1986600 Developmental Biology Correct dosage of Fog2 and Gata4 transcription factors is critical for fetal testis development in mice Gerrit J. Bouma, Linda L. Washburn, Kenneth H. Albrecht, and Eva M. Eicher Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 14994–14999. Published online 2007 September 11. doi: 10.1073/pnas.0701677104.PMCID: PMC1986601 Proteasomal selection of multiprotein complexes recruited by LIM homeodomain transcription factors Cenap Güngör, Naoko Taniguchi-Ishigaki, Hong Ma, Alexander Drung, Baris Tursun, Heather P. Ostendorff, Michael Bossenz, Catherina G. Becker, Thomas Becker, and Ingolf Bach Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15000–15005. Published online 2007 September 11. doi: 10.1073/pnas.0703738104.PMCID: PMC1986602 Evolution From the Cover: Strong coupling of predation intensity and diversity in the Phanerozoic fossil record John Warren Huntley and Michał Kowalewski Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15006–15010. Published online 2007 September 12. doi: 10.1073/pnas.0704960104.PMCID: PMC1986603 Different cognitive processes underlie human mate choices and mate preferences Peter M. Todd, Lars Penke, Barbara Fasolo, and Alison P. Lenton Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15011–15016. Published online 2007 September 7. doi: 10.1073/pnas.0705290104.PMCID: PMC1986604 From the Cover: Coupling of dispersal and aggression facilitates the rapid range expansion of a passerine bird Renée A. Duckworth and Alexander V. Badyaev Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15017–15022. Published online 2007 September 7. doi: 10.1073/pnas.0706174104.PMCID: PMC1986605 The hypothesis of reproductive compensation and its assumptions about mate preferences and offspring viability Patricia Adair Gowaty, Wyatt W. Anderson, Cynthia K. Bluhm, Lee C. Drickamer, Yong-Kyu Kim, and Allen J. Moore Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15023–15027. Published online 2007 September 11. doi: 10.1073/pnas.0706622104.PMCID: PMC1986606 Genetics Dual-specificity splice sites function alternatively as 5′ and 3′ splice sites Chaolin Zhang, Michelle L. Hastings, Adrian R. Krainer, and Michael Q. Zhang Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15028–15033. Published online 2007 September 11. doi: 10.1073/pnas.0703773104.PMCID: PMC1986607 Visualizing the dynamics of p21Waf1/Cip1 cyclin-dependent kinase inhibitor expression in living animals Naoko Ohtani, Yuko Imamura, Kimi Yamakoshi, Fumiko Hirota, Rika Nakayama, Yoshiaki Kubo, Naozumi Ishimaru, Akiko Takahashi, Atsushi Hirao, Takatsune Shimizu, David J. Mann, Hideyuki Saya, Yoshio Hayashi, Seiji Arase, Mitsuru Matsumoto, Nakao Kazuki, and Eiji Hara Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15034–15039. Published online 2007 September 11. doi: 10.1073/pnas.0706949104.PMCID: PMC1975854 Insulin gene mutations as a cause of permanent neonatal diabetes Julie Støy, Emma L. Edghill, Sarah E. Flanagan, Honggang Ye, Veronica P. Paz, Anna Pluzhnikov, Jennifer E. Below, M. Geoffrey Hayes, Nancy J. Cox, Gregory M. Lipkind, Rebecca B. Lipton, Siri Atma W. Greeley, Ann-Marie Patch, Sian Ellard, Donald F. Steiner, Andrew T. Hattersley, Louis H. Philipson, Graeme I. Bell, and Neonatal Diabetes International Collaborative Group Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15040–15044. Published online 2007 September 12. doi: 10.1073/pnas.0707291104.PMCID: PMC1986609 Immunology Increased competition for antigen during priming negatively impacts the generation of memory CD4 T cells David A. Blair and Leo Lefrançois Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15045–15050. Published online 2007 September 7. doi: 10.1073/pnas.0703767104.PMCID: PMC1986610 Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1 Paul A. Ramsland, Natasha Willoughby, Halina M. Trist, William Farrugia, P. Mark Hogarth, John D. Fraser, and Bruce D. Wines Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15051–15056. Published online 2007 September 11. doi: 10.1073/pnas.0706028104.PMCID: PMC1986611 Activation of naturally occurring lung CD4+CD25+ regulatory T cells requires CD8 and MHC I interaction Anthony Joetham, Katsuyuki Takeda, Nobuaki Miyahara, Shigeki Matsubara, Hiroshi Ohnishi, Toshiyuki Koya, Azzeddine Dakhama, and Erwin W. Gelfand Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15057–15062. Published online 2007 September 12. doi: 10.1073/pnas.0706765104.PMCID: PMC1986612 Chicken cathelicidin-B1, an antimicrobial guardian at the mucosal M cell gateway Ryo Goitsuka, Chen-lo H. Chen, Lesley Benyon, Yusuke Asano, Daisuke Kitamura, and Max D. Cooper Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15063–15068. Published online 2007 September 7. doi: 10.1073/pnas.0707037104.PMCID: PMC1986613 Medical Sciences Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1 Hyeung-Jin Jang, Zaza Kokrashvili, Michael J. Theodorakis, Olga D. Carlson, Byung-Joon Kim, Jie Zhou, Hyeon Ho Kim, Xiangru Xu, Sic L. Chan, Magdalena Juhaszova, Michel Bernier, Bedrich Mosinger, Robert F. Margolskee, and Josephine M. Egan Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15069–15074. Published online 2007 August 27. doi: 10.1073/pnas.0706890104.PMCID: PMC1986614 From the Cover: T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1 Robert F. Margolskee, Jane Dyer, Zaza Kokrashvili, Kieron S. H. Salmon, Erwin Ilegems, Kristian Daly, Emeline L. Maillet, Yuzo Ninomiya, Bedrich Mosinger, and Soraya P. Shirazi-Beechey Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15075–15080. Published online 2007 August 27. doi: 10.1073/pnas.0706678104.PMCID: PMC1986615 Myocardial ischemia results in tetrahydrobiopterin (BH4) oxidation with impaired endothelial function ameliorated by BH4 Cristian Dumitrescu, Roberto Biondi, Yong Xia, Arturo J. Cardounel, Lawrence J. Druhan, Giuseppe Ambrosio, and Jay L. Zweier Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15081–15086. Published online 2007 September 11. doi: 10.1073/pnas.0702986104.PMCID: PMC1986616 Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation Francesco Grassi, Gianluca Tell, Michaela Robbie-Ryan, Yuhao Gao, Masakazu Terauchi, Xiaoying Yang, Milena Romanello, Dean P. Jones, M. Neale Weitzmann, and Roberto Pacifici Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15087–15092. Published online 2007 September 11. doi: 10.1073/pnas.0703610104.PMCID: PMC1986617 High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1 Naoki Terasaka, Nan Wang, Laurent Yvan-Charvet, and Alan R. Tall Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15093–15098. Published online 2007 September 10. doi: 10.1073/pnas.0704602104.PMCID: PMC1986618 Microbiology Biosynthesis of 2-methylbacteriohopanepolyols by an anoxygenic phototroph Sky E. Rashby, Alex L. Sessions, Roger E. Summons, and Dianne K. Newman Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15099–15104. Published online 2007 September 11. doi: 10.1073/pnas.0704912104.PMCID: PMC1986619 Envelope variation as a primary determinant of lentiviral vaccine efficacy Jodi K. Craigo, Baoshan Zhang, Shannon Barnes, Tara L. Tagmyer, Sheila J. Cook, Charles J. Issel, and Ronald C. Montelaro Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15105–15110. Published online 2007 September 10. doi: 10.1073/pnas.0706449104.PMCID: PMC1986620 Neuroscience Nonhuman primate event-related potentials indexing covert shifts of attention Geoffrey F. Woodman, Min-Suk Kang, Andrew F. Rossi, and Jeffrey D. Schall Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15111–15116. Published online 2007 September 11. doi: 10.1073/pnas.0703477104.PMCID: PMC1986621 Genetic contributions to white matter architecture revealed by diffusion tensor imaging in Williams syndrome Stefano Marenco, Michael A. Siuta, J. Shane Kippenhan, Samuel Grodofsky, Wei-li Chang, Philip Kohn, Carolyn B. Mervis, Colleen A. Morris, Daniel R. Weinberger, Andreas Meyer-Lindenberg, Carlo Pierpaoli, and Karen Faith Berman Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15117–15122. Published online 2007 September 7. doi: 10.1073/pnas.0704311104.PMCID: PMC1986622 Human cone photoreceptor dependence on RPE65 isomerase Samuel G. Jacobson, Tomas S. Aleman, Artur V. Cideciyan, Elise Heon, Marcin Golczak, William A. Beltran, Alexander Sumaroka, Sharon B. Schwartz, Alejandro J. Roman, Elizabeth A. M. Windsor, James M. Wilson, Gustavo D. Aguirre, Edwin M. Stone, and Krzysztof Palczewski Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15123–15128. Published online 2007 September 11. doi: 10.1073/pnas.0706367104.PMCID: PMC1986623 Color contrast processing in human striate cortex R. W. Kentridge, C. A. Heywood, and L. Weiskrantz Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15129–15131. Published online 2007 September 6. doi: 10.1073/pnas.0706603104.PMCID: PMC1986624 Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching Zilu Wu, Anindya Ghosh-Roy, Mehmet Fatih Yanik, Jin Z. Zhang, Yishi Jin, and Andrew D. Chisholm Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15132–15137. Published online 2007 September 11. doi: 10.1073/pnas.0707001104.PMCID: PMC1975853 Effects of simian immunodeficiency virus on the circadian rhythms of body temperature and gross locomotor activity Salvador Huitron-Resendiz, Maria Cecilia G. Marcondes, Claudia T. Flynn, Caroline M. S. Lanigan, and Howard S. Fox Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15138–15143. Published online 2007 September 10. doi: 10.1073/pnas.0707171104.PMCID: PMC1986626 Physiology MicroRNA regulation of cyclooxygenase-2 during embryo implantation Anindita Chakrabarty, Susanne Tranguch, Takiko Daikoku, Kevin Jensen, Henry Furneaux, and Sudhansu K. Dey Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15144–15149. Published online 2007 September 11. doi: 10.1073/pnas.0705917104.PMCID: PMC1986627 Plant Biology Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction Sandy Vanderauwera, Marc De Block, Nancy Van de Steene, Brigitte van de Cotte, Michael Metzlaff, and Frank Van Breusegem Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15150–15155. Published online 2007 September 6. doi: 10.1073/pnas.0706668104.PMCID: PMC1986628 RNAi-mediated gene silencing reveals involvement of Arabidopsis chromatin-related genes in Agrobacterium-mediated root transformation Yan Ma Crane and Stanton B. Gelvin Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15156–15161. Published online 2007 September 7. doi: 10.1073/pnas.0706986104.PMCID: PMC1986629 Population Biology DNA evidence for historic population size and past ecosystem impacts of gray whales S. Elizabeth Alter, Eric Rynes, and Stephen R. Palumbi Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15162–15167. Published online 2007 September 11. doi: 10.1073/pnas.0706056104.PMCID: PMC1975855 Social Sciences Psychology Different cognitive processes underlie human mate choices and mate preferences Peter M. Todd, Lars Penke, Barbara Fasolo, and Alison P. Lenton Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15011–15016. Published online 2007 September 7. doi: 10.1073/pnas.0705290104.PMCID: PMC1986604 Correction Correction for Bock-Axelsen et al., Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles Jacob Bock Axelsen, Joseph Lotem, Leo Sachs, and Eytan Domany Proc Natl Acad Sci U S A. 2007 September 18; 104(38): 15168. Published online 2007 September 7. doi: 10.1073/pnas.0707795104.PMCID: PMC1986631 Corrects: Jacob Bock Axelsen, et al. Genes overexpressed in different human solid cancers exhibit different tissue-specific expression profiles. Proc Natl Acad Sci U S A. 2007 August 7; 104(32): 13122–13127. |