| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15275–15276. doi: 10.1073/iti4206103.PMCID: PMC1622816 Commentaries Salmon-farming impacts on wild salmon Ray Hilborn Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15277. Published online 2006 October 9. doi: 10.1073/pnas.0607419103.PMCID: PMC1622817 MicroRNAs and osmotic regulation James B. Uney and Stafford L. Lightman Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15278–15279. Published online 2006 October 9. doi: 10.1073/pnas.0607655103.PMCID: PMC1636800 Polymerization Special Feature Introduction Introduction: Polymerization Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15288. Published online 2006 October 10. doi: 10.1073/pnas.0606076103.PMCID: PMC1622819 Research Articles Kinetic resolution of racemic α-olefins with ansa-zirconocene polymerization catalysts: Enantiomorphic site vs. chain end control Jeffery A. Byers and John E. Bercaw Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15303–15308. Published online 2006 October 10. doi: 10.1073/pnas.0603071103.PMCID: PMC1622822 Diminishing catalyst concentration in atom transfer radical polymerization with reducing agents Krzysztof Matyjaszewski, Wojciech Jakubowski, Ke Min, Wei Tang, Jinyu Huang, Wade A. Braunecker, and Nicolay V. Tsarevsky Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15309–15314. Published online 2006 October 10. doi: 10.1073/pnas.0602675103.PMCID: PMC1622823 Cyclic esters and cyclodepsipeptides derived from lactide and 2,5-morpholinediones Malcolm H. Chisholm, Judith C. Gallucci, and Hongfeng Yin Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15315–15320. Published online 2006 October 10. doi: 10.1073/pnas.0602662103.PMCID: PMC1622824 Design of stereoselective Ziegler–Natta propene polymerization catalysts Vincenzo Busico, Roberta Cipullo, Roberta Pellecchia, Sara Ronca, Giuseppina Roviello, and Giovanni Talarico Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15321–15326. Published online 2006 October 10. doi: 10.1073/pnas.0602856103.PMCID: PMC1622825 From the Cover: Polymerization Special Feature: Semicrystalline thermoplastic elastomeric polyolefins: Advances through catalyst development and macromolecular design Atsushi Hotta, Eric Cochran, Janne Ruokolainen, Vikram Khanna, Glenn H. Fredrickson, Edward J. Kramer, Yong-Woo Shin, Fumihiko Shimizu, Anna E. Cherian, Phillip D. Hustad, Jeffrey M. Rose, and Geoffrey W. Coates Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15327–15332. Published online 2006 October 10. doi: 10.1073/pnas.0602894103.PMCID: PMC1834831 Ansa-metallocene polymerization catalysts derived from [2+2]cycloaddition reactions of bis(1-methylethenyl-cyclopentadienyl)zirconium systems Jan Paradies, Gerald Kehr, Roland Fröhlich, and Gerhard Erker Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15333–15337. Published online 2006 October 10. doi: 10.1073/pnas.0602627103.PMCID: PMC1834832 “Dormant” secondary metal-alkyl complexes are not omnipresent Zygmunt Flisak and Tom Ziegler Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15338–15342. Published online 2006 October 10. doi: 10.1073/pnas.0602091103.PMCID: PMC1834833 Study of ligand substituent effects on the rate and stereoselectivity of lactide polymerization using aluminum salen-type initiators Pimpa Hormnirun, Edward L. Marshall, Vernon C. Gibson, Robert I. Pugh, and Andrew J. P. White Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15343–15348. Published online 2006 October 10. doi: 10.1073/pnas.0602765103.PMCID: PMC1622826 Metallocene-catalyzed alkene polymerization and the observation of Zr-allyls Clark R. Landis and Matthew D. Christianson Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15349–15354. Published online 2006 October 10. doi: 10.1073/pnas.0602704103.PMCID: PMC1834834 Reviews Surface science of single-site heterogeneous olefin polymerization catalysts Seong H. Kim and Gabor A. Somorjai Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15289–15294. Published online 2006 October 10. doi: 10.1073/pnas.0602346103.PMCID: PMC1622820 Nuclearity and cooperativity effects in binuclear catalysts and cocatalysts for olefin polymerization Hongbo Li and Tobin J. Marks Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15295–15302. Published online 2006 October 10. doi: 10.1073/pnas.0603396103.PMCID: PMC1622821 Physical Sciences Chemistry Kinetic resolution of racemic α-olefins with ansa-zirconocene polymerization catalysts: Enantiomorphic site vs. chain end control Jeffery A. Byers and John E. Bercaw Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15303–15308. Published online 2006 October 10. doi: 10.1073/pnas.0603071103.PMCID: PMC1622822 Diminishing catalyst concentration in atom transfer radical polymerization with reducing agents Krzysztof Matyjaszewski, Wojciech Jakubowski, Ke Min, Wei Tang, Jinyu Huang, Wade A. Braunecker, and Nicolay V. Tsarevsky Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15309–15314. Published online 2006 October 10. doi: 10.1073/pnas.0602675103.PMCID: PMC1622823 Cyclic esters and cyclodepsipeptides derived from lactide and 2,5-morpholinediones Malcolm H. Chisholm, Judith C. Gallucci, and Hongfeng Yin Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15315–15320. Published online 2006 October 10. doi: 10.1073/pnas.0602662103.PMCID: PMC1622824 Design of stereoselective Ziegler–Natta propene polymerization catalysts Vincenzo Busico, Roberta Cipullo, Roberta Pellecchia, Sara Ronca, Giuseppina Roviello, and Giovanni Talarico Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15321–15326. Published online 2006 October 10. doi: 10.1073/pnas.0602856103.PMCID: PMC1622825 From the Cover: Polymerization Special Feature: Semicrystalline thermoplastic elastomeric polyolefins: Advances through catalyst development and macromolecular design Atsushi Hotta, Eric Cochran, Janne Ruokolainen, Vikram Khanna, Glenn H. Fredrickson, Edward J. Kramer, Yong-Woo Shin, Fumihiko Shimizu, Anna E. Cherian, Phillip D. Hustad, Jeffrey M. Rose, and Geoffrey W. Coates Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15327–15332. Published online 2006 October 10. doi: 10.1073/pnas.0602894103.PMCID: PMC1834831 Ansa-metallocene polymerization catalysts derived from [2+2]cycloaddition reactions of bis(1-methylethenyl-cyclopentadienyl)zirconium systems Jan Paradies, Gerald Kehr, Roland Fröhlich, and Gerhard Erker Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15333–15337. Published online 2006 October 10. doi: 10.1073/pnas.0602627103.PMCID: PMC1834832 “Dormant” secondary metal-alkyl complexes are not omnipresent Zygmunt Flisak and Tom Ziegler Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15338–15342. Published online 2006 October 10. doi: 10.1073/pnas.0602091103.PMCID: PMC1834833 Study of ligand substituent effects on the rate and stereoselectivity of lactide polymerization using aluminum salen-type initiators Pimpa Hormnirun, Edward L. Marshall, Vernon C. Gibson, Robert I. Pugh, and Andrew J. P. White Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15343–15348. Published online 2006 October 10. doi: 10.1073/pnas.0602765103.PMCID: PMC1622826 Metallocene-catalyzed alkene polymerization and the observation of Zr-allyls Clark R. Landis and Matthew D. Christianson Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15349–15354. Published online 2006 October 10. doi: 10.1073/pnas.0602704103.PMCID: PMC1834834 Inhomogeneous dynamics in confined water nanodroplets Adriaan M. Dokter, Sander Woutersen, and Huib J. Bakker Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15355–15358. Published online 2006 October 6. doi: 10.1073/pnas.0603239103.PMCID: PMC1592463 DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators Jonathan R. Hart, Oleg Glebov, Russell J. Ernst, Ilan R. Kirsch, and Jacqueline K. Barton Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15359–15363. Published online 2006 October 9. doi: 10.1073/pnas.0607576103.PMCID: PMC1622828 Suppression of hypoxia-induced HIF-1α and of angiogenesis in endothelial cells by myo-inositol trispyrophosphate-treated erythrocytes Claudine Kieda, Ruth Greferath, Claire Crola Da Silva, Konstantina C. Fylaktakidou, Jean-Marie Lehn, and Claude Nicolau Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15576–15581. Published online 2006 October 6. doi: 10.1073/pnas.0607109103.PMCID: PMC1622864 Environmental Sciences An arsenic metallochaperone for an arsenic detoxification pump Yung-Feng Lin, Adrian R. Walmsley, and Barry P. Rosen Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15617–15622. Published online 2006 October 9. doi: 10.1073/pnas.0603974103.PMCID: PMC1622871 Mathematics Subelliptic boundary conditions for Spin –Dirac operators, gluing, relative indices, and tame Fredholm pairs Charles L. Epstein Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15364–15369. Published online 2006 October 10. doi: 10.1073/pnas.0605368103.PMCID: PMC1622829 Physics Protein folding is slaved to solvent motions H. Frauenfelder, P. W. Fenimore, G. Chen, and B. H. McMahon Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15469–15472. Published online 2006 October 9. doi: 10.1073/pnas.0607168103.PMCID: PMC1592535 Biological Sciences Agricultural Sciences l-Kynurenine, an amino acid identified as a sex pheromone in the urine of ovulated female masu salmon Hidenobu Yambe, Shoji Kitamura, Michiya Kamio, Miho Yamada, Shigeki Matsunaga, Nobuhiro Fusetani, and Fumio Yamazaki Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15370–15374. Published online 2006 October 9. doi: 10.1073/pnas.0604340103.PMCID: PMC1622830 Anthropology Divergent mtDNA lineages of goats in an Early Neolithic site, far from the initial domestication areas Helena Fernández, Sandrine Hughes, Jean-Denis Vigne, Daniel Helmer, Greg Hodgins, Christian Miquel, Catherine Hänni, Gordon Luikart, and Pierre Taberlet Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15375–15379. Published online 2006 October 9. doi: 10.1073/pnas.0602753103.PMCID: PMC1622831 Applied Biological Sciences Early-phase transmission of Yersinia pestis by unblocked fleas as a mechanism explaining rapidly spreading plague epizootics Rebecca J. Eisen, Scott W. Bearden, Aryn P. Wilder, John A. Montenieri, Michael F. Antolin, and Kenneth L. Gage Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15380–15385. Published online 2006 October 10. doi: 10.1073/pnas.0606831103.PMCID: PMC1592641 Biochemistry DNA mismatch-specific targeting and hypersensitivity of mismatch-repair-deficient cells to bulky rhodium(III) intercalators Jonathan R. Hart, Oleg Glebov, Russell J. Ernst, Ilan R. Kirsch, and Jacqueline K. Barton Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15359–15363. Published online 2006 October 9. doi: 10.1073/pnas.0607576103.PMCID: PMC1622828 Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center Neuza Satomi Sato, Naomi Hirabayashi, Ilana Agmon, Ada Yonath, and Tsutomu Suzuki Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15386–15391. Published online 2006 October 10. doi: 10.1073/pnas.0605970103.PMCID: PMC1592644 Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases Seunghee Lee, Dong-Kee Lee, Yali Dou, Jeongkyung Lee, Bora Lee, Eunyee Kwak, Young-Yun Kong, Soo-Kyung Lee, Robert G. Roeder, and Jae W. Lee Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15392–15397. Published online 2006 October 4. doi: 10.1073/pnas.0607313103.PMCID: PMC1622834 Mapping protein dynamics in catalytic intermediates of the redox-driven proton pump cytochrome c oxidase Laura S. Busenlehner, Lina Salomonsson, Peter Brzezinski, and Richard N. Armstrong Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15398–15403. Published online 2006 October 5. doi: 10.1073/pnas.0601451103.PMCID: PMC1622835 From the Cover: Acrolein is a major cigarette-related lung cancer agent: Preferential binding at p53 mutational hotspots and inhibition of DNA repair Zhaohui Feng, Wenwei Hu, Yu Hu, and Moon-shong Tang Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15404–15409. Published online 2006 October 9. doi: 10.1073/pnas.0607031103.PMCID: PMC1592536 Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1α Seung-Hun Cha, Joseph T. Rodgers, Pere Puigserver, Shigeru Chohnan, and M. Daniel Lane Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15410–15415. Published online 2006 October 9. doi: 10.1073/pnas.0607334103.PMCID: PMC1622837 Structural basis for Rab11-dependent membrane recruitment of a family of Rab11-interacting protein 3 (FIP3)/Arfophilin-1 Tomoo Shiba, Hiroshi Koga, Hye-Won Shin, Masato Kawasaki, Ryuichi Kato, Kazuhisa Nakayama, and Soichi Wakatsuki Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15416–15421. Published online 2006 October 9. doi: 10.1073/pnas.0605357103.PMCID: PMC1622838 Biophysics Hot-spot mimicry of a cytokine receptor by a small molecule Christopher D. Thanos, Warren L. DeLano, and James A. Wells Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15422–15427. Published online 2006 October 10. doi: 10.1073/pnas.0607058103.PMCID: PMC1592646 Shape and oligomerization state of the cytoplasmic domain of the phototaxis transducer II from Natronobacterium pharaonis Ivan L. Budyak, Vitaliy Pipich, Olga S. Mironova, Ramona Schlesinger, Giuseppe Zaccai, and Judith Klein-Seetharaman Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15428–15433. Published online 2006 October 10. doi: 10.1073/pnas.0607201103.PMCID: PMC1592645 Similarities between heterophilic and homophilic cadherin adhesion A. K. Prakasam, V. Maruthamuthu, and D. E. Leckband Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15434–15439. Published online 2006 October 5. doi: 10.1073/pnas.0606701103.PMCID: PMC1622841 Quantification and rationalization of the higher affinity of sodium over potassium to protein surfaces Luboš Vrbka, Jiří Vondrášek, Barbara Jagoda-Cwiklik, Robert Vácha, and Pavel Jungwirth Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15440–15444. Published online 2006 October 10. doi: 10.1073/pnas.0606959103.PMCID: PMC2047604 Proton–proton Overhauser NMR spectroscopy with polypeptide chains in large structures Reto Horst, Gerhard Wider, Jocelyne Fiaux, Eric B. Bertelsen, Arthur L. Horwich, and Kurt Wüthrich Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15445–15450. Published online 2006 October 10. doi: 10.1073/pnas.0607141103.PMCID: PMC1622842 Protein complex formation by acetylcholinesterase and the neurotoxin fasciculin-2 appears to involve an induced-fit mechanism Jennifer M. Bui and J. Andrew McCammon Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15451–15456. Published online 2006 October 4. doi: 10.1073/pnas.0605355103.PMCID: PMC1591298 A seven-helix coiled coil Jie Liu, Qi Zheng, Yiqun Deng, Chao-Sheng Cheng, Neville R. Kallenbach, and Min Lu Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15457–15462. Published online 2006 October 9. doi: 10.1073/pnas.0604871103.PMCID: PMC1622844 G protein-coupled receptors sense fluid shear stress in endothelial cells Mirianas Chachisvilis, Yan-Liang Zhang, and John A. Frangos Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15463–15468. Published online 2006 October 9. doi: 10.1073/pnas.0607224103.PMCID: PMC1622845 Protein folding is slaved to solvent motions H. Frauenfelder, P. W. Fenimore, G. Chen, and B. H. McMahon Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15469–15472. Published online 2006 October 9. doi: 10.1073/pnas.0607168103.PMCID: PMC1592535 Cell Biology Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting N. Fili, V. Calleja, R. Woscholski, P. J. Parker, and B. Larijani Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15473–15478. Published online 2006 October 9. doi: 10.1073/pnas.0607040103.PMCID: PMC1622847 Cell-surface heparan sulfate proteoglycans are essential components of the unconventional export machinery of FGF-2 Christoph Zehe, André Engling, Sabine Wegehingel, Tobias Schäfer, and Walter Nickel Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15479–15484. Published online 2006 October 9. doi: 10.1073/pnas.0605997103.PMCID: PMC1622848 Diacylglycerol kinase δ regulates protein kinase C and epidermal growth factor receptor signaling Tracy Crotty, Jinjin Cai, Fumio Sakane, Akinobu Taketomi, Stephen M. Prescott, and Matthew K. Topham Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15485–15490. Published online 2006 October 4. doi: 10.1073/pnas.0604104103.PMCID: PMC1622849 Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells Christopher Daly, Elizabeth Pasnikowski, Elena Burova, Vivian Wong, Thomas H. Aldrich, Jennifer Griffiths, Ella Ioffe, Thomas J. Daly, James P. Fandl, Nick Papadopoulos, Donald M. McDonald, Gavin Thurston, George D. Yancopoulos, and John S. Rudge Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15491–15496. Published online 2006 October 9. doi: 10.1073/pnas.0607538103.PMCID: PMC1592534 Ecology Pinoresinol: A lignol of plant origin serving for defense in a caterpillar Frank C. Schroeder, Marta L. del Campo, Jacqualine B. Grant, Douglas B. Weibel, Scott R. Smedley, Kelly L. Bolton, Jerrold Meinwald, and Thomas Eisner Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15497–15501. Published online 2006 October 9. doi: 10.1073/pnas.0605921103.PMCID: PMC1622851 Predicted climate change alters the indirect effect of predators on an ecosystem process Janet R. Lensing and David H. Wise Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15502–15505. Published online 2006 October 5. doi: 10.1073/pnas.0607064103.PMCID: PMC1622852 From the Cover: Epizootics of wild fish induced by farm fish Martin Krkošek, Mark A. Lewis, Alexandra Morton, L. Neil Frazer, and John P. Volpe Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15506–15510. Published online 2006 October 4. doi: 10.1073/pnas.0603525103.PMCID: PMC1591297 Evolution The deepest divergences in land plants inferred from phylogenomic evidence Yin-Long Qiu, Libo Li, Bin Wang, Zhiduan Chen, Volker Knoop, Milena Groth-Malonek, Olena Dombrovska, Jungho Lee, Livija Kent, Joshua Rest, George F. Estabrook, Tory A. Hendry, David W. Taylor, Christopher M. Testa, Mathew Ambros, Barbara Crandall-Stotler, R. Joel Duff, Michael Stech, Wolfgang Frey, Dietmar Quandt, and Charles C. Davis Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15511–15516. Published online 2006 October 9. doi: 10.1073/pnas.0603335103.PMCID: PMC1622854 Genetics Global roles of Ste11p, cell type, and pheromone in the control of gene expression during early sexual differentiation in fission yeast Juan Mata and Jürg Bähler Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15517–15522. Published online 2006 October 9. doi: 10.1073/pnas.0603403103.PMCID: PMC1592531 A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance Iryna Zubovych, Thomas Doundoulakis, Patrick G. Harran, and Michael G. Roth Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15523–15528. Published online 2006 October 10. doi: 10.1073/pnas.0607338103.PMCID: PMC1622856 Immunology Critical role for the β regulatory subunits of Cav channels in T lymphocyte function Abdallah Badou, Mithilesh Kumar Jha, Didi Matza, Wajahat Z. Mehal, Marc Freichel, Veit Flockerzi, and Richard A. Flavell Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15529–15534. Published online 2006 October 6. doi: 10.1073/pnas.0607262103.PMCID: PMC1622857 Increased susceptibility to bacterial superinfection as a consequence of innate antiviral responses Alexander A. Navarini, Mike Recher, Karl S. Lang, Panco Georgiev, Susanne Meury, Andreas Bergthaler, Lukas Flatz, Jacques Bille, Regine Landmann, Bernhard Odermatt, Hans Hengartner, and Rolf M. Zinkernagel Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15535–15539. Published online 2006 October 9. doi: 10.1073/pnas.0607325103.PMCID: PMC1622858 Medical Sciences Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor Weisheng Xu, Lang Ngo, Gisela Perez, Milos Dokmanovic, and Paul A. Marks Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15540–15545. Published online 2006 October 9. doi: 10.1073/pnas.0607518103.PMCID: PMC1592530 FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction Felix B. Engel, Patrick C. H. Hsieh, Richard T. Lee, and Mark T. Keating Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15546–15551. Published online 2006 October 10. doi: 10.1073/pnas.0607382103.PMCID: PMC1622860 Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling Masaya Baba, Seung-Beom Hong, Nirmala Sharma, Michelle B. Warren, Michael L. Nickerson, Akihiro Iwamatsu, Dominic Esposito, William K. Gillette, Ralph F. Hopkins, III, James L. Hartley, Mutsuo Furihata, Shinya Oishi, Wei Zhen, Terrence R. Burke, Jr., W. Marston Linehan, Laura S. Schmidt, and Berton Zbar Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15552–15557. Published online 2006 October 6. doi: 10.1073/pnas.0603781103.PMCID: PMC1592464 Germ-line mutations in p27Kip1 cause a multiple endocrine neoplasia syndrome in rats and humans Natalia S. Pellegata, Leticia Quintanilla-Martinez, Heide Siggelkow, Elenore Samson, Karin Bink, Heinz Höfler, Falko Fend, Jochen Graw, and Michael J. Atkinson Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15558–15563. Published online 2006 October 9. doi: 10.1073/pnas.0603877103.PMCID: PMC1622862 Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways Krzysztof Laudanski, Carol Miller-Graziano, Wenzhong Xiao, Michael N. Mindrinos, Daniel R. Richards, Asit De, Lyle L. Moldawer, Ronald V. Maier, Paul Bankey, Henry V. Baker, Bernard H. Brownstein, J. Perren Cobb, Steve E. Calvano, Ronald W. Davis, Ronald G. Tompkins, and Inflammation and Host Response to Injury Large-Scale Collaborative Research Program Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15564–15569. Published online 2006 October 10. doi: 10.1073/pnas.0607028103.PMCID: PMC1592643 An 85-aa segment of the GB virus type C NS5A phosphoprotein inhibits HIV-1 replication in CD4+ Jurkat T cells Jinhua Xiang, James H. McLinden, Qing Chang, Thomas M. Kaufman, and Jack T. Stapleton Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15570–15575. Published online 2006 October 9. doi: 10.1073/pnas.0604728103.PMCID: PMC1622863 Suppression of hypoxia-induced HIF-1α and of angiogenesis in endothelial cells by myo-inositol trispyrophosphate-treated erythrocytes Claudine Kieda, Ruth Greferath, Claire Crola Da Silva, Konstantina C. Fylaktakidou, Jean-Marie Lehn, and Claude Nicolau Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15576–15581. Published online 2006 October 6. doi: 10.1073/pnas.0607109103.PMCID: PMC1622864 Microbiology INAUGURAL ARTICLE by a Recently Elected Academy Member: Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp genome shaped for versatility Patrick S. G. Chain, Vincent J. Denef, Konstantinos T. Konstantinidis, Lisa M. Vergez, Loreine Agulló, Valeria Latorre Reyes, Loren Hauser, Macarena Córdova, Luis Gómez, Myriam González, Miriam Land, Victoria Lao, Frank Larimer, John J. LiPuma, Eshwar Mahenthiralingam, Stephanie A. Malfatti, Christopher J. Marx, J. Jacob Parnell, Alban Ramette, Paul Richardson, Michael Seeger, Daryl Smith, Theodore Spilker, Woo Jun Sul, Tamara V. Tsoi, Luke E. Ulrich, Igor B. Zhulin, and James M. Tiedje Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15280–15287. Published online 2006 October 9. doi: 10.1073/pnas.0606924103.PMCID: PMC1622818 The complete genome of Rhodococcus sp. RHA1 provides insights into a catabolic powerhouse Michael P. McLeod, René L. Warren, William W. L. Hsiao, Naoto Araki, Matthew Myhre, Clinton Fernandes, Daisuke Miyazawa, Wendy Wong, Anita L. Lillquist, Dennis Wang, Manisha Dosanjh, Hirofumi Hara, Anca Petrescu, Ryan D. Morin, George Yang, Jeff M. Stott, Jacqueline E. Schein, Heesun Shin, Duane Smailus, Asim S. Siddiqui, Marco A. Marra, Steven J. M. Jones, Robert Holt, Fiona S. L. Brinkman, Keisuke Miyauchi, Masao Fukuda, Julian E. Davies, William W. Mohn, and Lindsay D. Eltis Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15582–15587. Published online 2006 October 9. doi: 10.1073/pnas.0607048103.PMCID: PMC1622865 High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition Ya-Lin Chiu, H. Ewa Witkowska, Steven C. Hall, Mario Santiago, Vanessa B. Soros, Cécile Esnault, Thierry Heidmann, and Warner C. Greene Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15588–15593. Published online 2006 October 9. doi: 10.1073/pnas.0604524103.PMCID: PMC1592537 A deletion defining a common Asian lineage of Mycobacterium tuberculosis associates with immune subversion Sandra M. Newton, Rebecca J. Smith, Katalin A. Wilkinson, Mark P. Nicol, Natalie J. Garton, Karl J. Staples, Graham R. Stewart, John R. Wain, Adrian R. Martineau, Sarah Fandrich, Timothy Smallie, Brian Foxwell, Ahmed Al-Obaidi, Jamila Shafi, Kumar Rajakumar, Beate Kampmann, Peter W. Andrew, Loems Ziegler-Heitbrock, Michael R. Barer, and Robert J. Wilkinson Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15594–15598. Published online 2006 October 6. doi: 10.1073/pnas.0604283103.PMCID: PMC1622867 Chlamydial TARP is a bacterial nucleator of actin Travis J. Jewett, Elizabeth R. Fischer, David J. Mead, and Ted Hackstadt Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15599–15604. Published online 2006 October 6. doi: 10.1073/pnas.0603044103.PMCID: PMC1622868 Pseudomonas aeruginosa type III-secreted toxin ExoT inhibits host-cell division by targeting cytokinesis at multiple steps Sasha H. Shafikhani and Joanne Engel Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15605–15610. Published online 2006 October 9. doi: 10.1073/pnas.0605949103.PMCID: PMC1622869 Comparative genomics of the lactic acid bacteria K. Makarova, A. Slesarev, Y. Wolf, A. Sorokin, B. Mirkin, E. Koonin, A. Pavlov, N. Pavlova, V. Karamychev, N. Polouchine, V. Shakhova, I. Grigoriev, Y. Lou, D. Rohksar, S. Lucas, K. Huang, D. M. Goodstein, T. Hawkins, V. Plengvidhya, D. Welker, J. Hughes, Y. Goh, A. Benson, K. Baldwin, J.-H. Lee, I. Díaz-Muñiz, B. Dosti, V. Smeianov, W. Wechter, R. Barabote, G. Lorca, E. Altermann, R. Barrangou, B. Ganesan, Y. Xie, H. Rawsthorne, D. Tamir, C. Parker, F. Breidt, J. Broadbent, R. Hutkins, D. O'Sullivan, J. Steele, G. Unlu, M. Saier, T. Klaenhammer, P. Richardson, S. Kozyavkin, B. Weimer, and D. Mills Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15611–15616. Published online 2006 October 9. doi: 10.1073/pnas.0607117103.PMCID: PMC1622870 An arsenic metallochaperone for an arsenic detoxification pump Yung-Feng Lin, Adrian R. Walmsley, and Barry P. Rosen Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15617–15622. Published online 2006 October 9. doi: 10.1073/pnas.0603974103.PMCID: PMC1622871 Neuroscience Human fronto–mesolimbic networks guide decisions about charitable donation Jorge Moll, Frank Krueger, Roland Zahn, Matteo Pardini, Ricardo de Oliveira-Souza, and Jordan Grafman Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15623–15628. Published online 2006 October 9. doi: 10.1073/pnas.0604475103.PMCID: PMC1622872 Eph tyrosine kinase receptor EphA4 is required for the topographic mapping of the corticospinal tract Alison J. Canty, Ursula Greferath, Ann M. Turnley, and Mark Murphy Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15629–15634. Published online 2006 October 9. doi: 10.1073/pnas.0607350103.PMCID: PMC1622873 Interplay between PIP3 and calmodulin regulation of olfactory cyclic nucleotide-gated channels James D. Brady, Elizabeth D. Rich, Jeffrey R. Martens, Jeffrey W. Karpen, Michael D. Varnum, and R. Lane Brown Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15635–15640. Published online 2006 October 10. doi: 10.1073/pnas.0603344103.PMCID: PMC1622874 Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry Gene-Jack Wang, Julia Yang, Nora D. Volkow, Frank Telang, Yeming Ma, Wei Zhu, Christopher T. Wong, Dardo Tomasi, Panayotis K. Thanos, and Joanna S. Fowler Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15641–15645. Published online 2006 October 5. doi: 10.1073/pnas.0601977103.PMCID: PMC1592230 A beta2-frequency (20–30 Hz) oscillation in nonsynaptic networks of somatosensory cortex Anita K. Roopun, Steven J. Middleton, Mark O. Cunningham, Fiona E. N. LeBeau, Andrea Bibbig, Miles A. Whittington, and Roger D. Traub Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15646–15650. Published online 2006 October 9. doi: 10.1073/pnas.0607443103.PMCID: PMC1592532 Fronto-cerebellar systems are associated with infant motor and adult executive functions in healthy adults but not in schizophrenia Khanum Ridler, Juha M. Veijola, Päivikki Tanskanen, Jouko Miettunen, Xavier Chitnis, John Suckling, Graham K. Murray, Marianne Haapea, Peter B. Jones, Matti K. Isohanni, and Edward T. Bullmore Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15651–15656. Published online 2006 October 6. doi: 10.1073/pnas.0602639103.PMCID: PMC1636802 Switching off calcium-dependent inactivation in l-type calcium channels by an autoinhibitory domain Christian Wahl-Schott, Ludwig Baumann, Hartmut Cuny, Christian Eckert, Kristina Griessmeier, and Martin Biel Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15657–15662. Published online 2006 October 6. doi: 10.1073/pnas.0604621103.PMCID: PMC1622877 Ionic control of ocular growth and refractive change Sheila G. Crewther, Helena Liang, Barbara M. Junghans, and David P. Crewther Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15663–15668. Published online 2006 October 5. doi: 10.1073/pnas.0607241103.PMCID: PMC1622878 From the Cover: miR-7b, a microRNA up-regulated in the hypothalamus after chronic hyperosmolar stimulation, inhibits Fos translation Heon-Jin Lee, Miklós Palkovits, and W. Scott Young, III Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15669–15674. Published online 2006 October 6. doi: 10.1073/pnas.0605781103.PMCID: PMC1622879 Physiology Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects Brian J. Feldman, Ryan S. Streeper, Robert V. Farese, Jr., and Keith R. Yamamoto Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15675–15680. Published online 2006 October 9. doi: 10.1073/pnas.0607501103.PMCID: PMC1592529 Running over rough terrain reveals limb control for intrinsic stability Monica A. Daley and Andrew A. Biewener Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15681–15686. Published online 2006 October 10. doi: 10.1073/pnas.0601473103.PMCID: PMC1622881 Plant Biology Methionine catabolism in Arabidopsis cells is initiated by a γ-cleavage process and leads to S-methylcysteine and isoleucine syntheses Fabrice Rébeillé, Samuel Jabrin, Richard Bligny, Karen Loizeau, Bernadette Gambonnet, Valérie Van Wilder, Roland Douce, and Stéphane Ravanel Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15687–15692. Published online 2006 October 9. doi: 10.1073/pnas.0606195103.PMCID: PMC1622882 Population Biology Uncertainty in predictions of disease spread and public health responses to bioterrorism and emerging diseases Bret D. Elderd, Vanja M. Dukic, and Greg Dwyer Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15693–15697. Published online 2006 October 9. doi: 10.1073/pnas.0600816103.PMCID: PMC1592533 Psychology Transforming reflectance spectra into Munsell color space by using prime colors A. Kimball Romney and James T. Fulton Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15698–15703. Published online 2006 October 9. doi: 10.1073/pnas.0607488103.PMCID: PMC1622884 Visual saliency and texture segregation without feature gradient Ohad Ben-Shahar Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15704–15709. Published online 2006 October 9. doi: 10.1073/pnas.0604410103.PMCID: PMC1622885 Mathematical analysis of locomotor behavior by mice in a radial maze Allan D. Coop, Mihaela A. Stavarache, Donald W. Pfaff, and George N. Reeke Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15710–15715. Published online 2006 October 9. doi: 10.1073/pnas.0607258103.PMCID: PMC1622886 Programming social, cognitive, and neuroendocrine development by early exposure to novelty Akaysha C. Tang, Katherine G. Akers, Bethany C. Reeb, Russell D. Romeo, and Bruce S. McEwen Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15716–15721. Published online 2006 October 9. doi: 10.1073/pnas.0607374103.PMCID: PMC1622887 Sustainability Science From the Cover: Epizootics of wild fish induced by farm fish Martin Krkošek, Mark A. Lewis, Alexandra Morton, L. Neil Frazer, and John P. Volpe Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15506–15510. Published online 2006 October 4. doi: 10.1073/pnas.0603525103.PMCID: PMC1591297 Social Sciences Psychology Programming social, cognitive, and neuroendocrine development by early exposure to novelty Akaysha C. Tang, Katherine G. Akers, Bethany C. Reeb, Russell D. Romeo, and Bruce S. McEwen Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15716–15721. Published online 2006 October 9. doi: 10.1073/pnas.0607374103.PMCID: PMC1622887 Correction Correction for Ebrahem et al., Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration Proc Natl Acad Sci U S A. 2006 October 17; 103(42): 15722. Published online 2006 October 3. doi: 10.1073/pnas.0607578103.PMCID: PMC1622888 Corrects: Quteba Ebrahem, et al. Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration. Proc Natl Acad Sci U S A. 2006 September 5; 103(36): 13480–13484. |