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Found 75 studies with search of: "Tipifarnib"
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Rank Status Study
1 Completed Zarnestra and Gleevec in Chronic Phase Chronic Myelogenous Leukemia
Condition: Leukemia, Myeloid, Chronic
Interventions: Drug: R115777 (Zarnestra);   Drug: Imatinib mesylate (Gleevec)
2 Completed Study of Letrozole Plus Tipifarnib or Placebo in the Treatment of Advanced Breast Cancer
Condition: Breast Cancer
Intervention: Drug: ZARNESTRA, tipifarnib, R115777
3 Completed Study of Tipifarnib in Patients With High-Risk Myelodysplastic Syndrome (MDS)
Condition: Myelodysplastic Syndrome
Intervention: Drug: ZARNESTRA, tipifarnib, R115777
4 Completed Study of Tipifarnib as Postconsolidation Therapy for Acute Myeloid Leukemia in Patients 60 Years and Older
Condition: Acute Myeloid Leukemia
Intervention: Drug: ZARNESTRA, tipifarnib, R115777
5 Completed Tipifarnib Versus Best Supportive Care in the Treatment of Newly Diagnosed Acute Myeloid Leukemia (AML)
Condition: Acute Myeloid Leukemia
Intervention: Procedure: Tipifarnib;Zarnestra; R115777
6 Completed A Phase 2 Study of Farnesyl Transferase Inhibitor (R115777, Tipifarnib) in Patients With Refractory or Relapsed Acute Myeloid Leukemia.
Condition: Leukemia, Nonlymphocytic, Acute
Intervention: Drug: tipifarnib (R115777)
7 Terminated Efficacy and Safety of the Farnesyl-Transferase Inhibitor (Tipifarnib) in Mantle Cell Lymphoma
Condition: Mantle Cell Lymphoma
Intervention: Drug: ZARNESTRA (Tipifarnib)
8 Active, not recruiting Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia
Condition: Leukemia
Interventions: Drug: etoposide;   Drug: tipifarnib
9 Recruiting Tipifarnib and Combination Chemotherapy in Treating Patients With Stage II or Stage III Breast Cancer
Condition: Breast Cancer
Interventions: Biological: pegfilgrastim;   Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: paclitaxel;   Drug: tipifarnib;   Procedure: axillary lymph node dissection;   Procedure: conventional surgery
10 Active, not recruiting Response to Tipifarnib in Individuals With Large Granular Lymphocyte Leukemia
Conditions: Leukemia, Lymphocytic;   Neutropenia;   Anemia
Intervention: Drug: Tipifarnib
11 Recruiting Tipifarnib and Etoposide in Treating Older Patients With Newly Diagnosed, Previously Untreated Acute Myeloid Leukemia
Condition: Leukemia
Interventions: Drug: etoposide;   Drug: tipifarnib
12 Active, not recruiting Capecitabine and Tipifarnib in Treating Women With Taxane-Resistant Metastatic Breast Cancer
Condition: Breast Cancer
Interventions: Drug: capecitabine;   Drug: tipifarnib
13 Active, not recruiting Tipifarnib and Fulvestrant as Second-Line Therapy in Treating Postmenopausal Women With Hormone Receptor-Positive Inoperable Locally Advanced or Metastatic Breast Cancer With Progressive Disease After Previous First-Line Endocrine Therapy
Condition: Breast Cancer
Interventions: Drug: fulvestrant;   Drug: tipifarnib
14 Suspended Tipifarnib and Gemcitabine in Treating Women With Metastatic Breast Cancer
Condition: Breast Cancer
Interventions: Drug: gemcitabine hydrochloride;   Drug: tipifarnib
15 Completed Tipifarnib Plus Tamoxifen in Treating Women With Metastatic Breast Cancer
Condition: Breast Cancer
Interventions: Drug: tamoxifen citrate;   Drug: tipifarnib
16 Suspended Tipifarnib and Sorafenib in Treating Patients With Advanced Cancer
Condition: Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: sorafenib tosylate;   Drug: tipifarnib
17 Completed Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer
Condition: Breast Cancer
Interventions: Biological: filgrastim;   Drug: cyclophosphamide;   Drug: doxorubicin hydrochloride;   Drug: tipifarnib;   Procedure: conventional surgery
18 Active, not recruiting Tipifarnib in Treating Older Patients With Acute Myeloid Leukemia
Condition: Leukemia
Intervention: Drug: tipifarnib
19 Recruiting Tipifarnib and Bortezomib in Treating Patients With Acute Leukemia or Chronic Myelogenous Leukemia in Blast Phase
Condition: Leukemia
Interventions: Drug: bortezomib;   Drug: tipifarnib;   Genetic: protein expression analysis;   Other: immunohistochemistry staining method;   Procedure: biopsy
20 Terminated A Combination of Zarnestra With Velcade for Patients With Relapsed Multiple Myeloma
Condition: Multiple Myeloma
Interventions: Drug: PS-341 (Velcade);   Drug: R11577 (Zarnestra)

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