Dwight W. Miller, Ph.D., Division of Chemistry, FDA, National Center for Toxicological Research

Oklahoma State University, B.S., 1968, Technical Education (Chemistry), Stillwater, Oklahoma
Oklahoma State University, Ph.D., 1977, Chemistry,
Oklahoma State University, Ph.D. (Physical-Organic Chemistry), Stillwater, Oklahoma

Experience:

• 1974-1976 Research Associate, Florida State University, Tallahassee, FL
• Northern Oklahoma College, Department of Science and Engineering, Tonkawa, OK.
• 6/78 to 9/78 - Research Chemist, Continental Oil Company, Analytical Services Division, Ponca City, OK.
• 8/83 to 2/86 - Consultant, Bowman and Associates, Pine Bluff, AR
• 10/79 to 9/81 - Chemist, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR
• 9/81 to 7/85 - Chemist(1320 GS-12) National Center for Toxicological Research, Division of Chemistry, Jefferson, AR.
• 7/85 to 5/93 - Chemist(1320 GS-13) National Center for Toxicological Research, Division of Chemistry, and Division of Biochemical Toxicology, Jefferson, AR.
• 5/93 to present - Chemist(1320 GS-14), National Center for Toxicological Research, Division of Chemistry, Jefferson, AR.
• 1989-1996 Project Officer for the Synthesis Contract, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR.
• November 1997 to May 1998, assigned to Team Leader for the Chemistry Program in the Division of Microbiology and Chemistry, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR.
• May 1998 to July 1998 served as Acting Director, Division of Chemistry, National Center for Toxicological Research, Division of Chemistry, Jefferson, AR.

Honors:

• 1999 Award "Best of What’s New" from Popular Science for "Fresh Tag™".
• FDA Award of Merit 1999, for technology transfer.
• Federal Laboratory Consortium, 1999 Award for Technology Transfer, Salt Lake City, UT. (This was the first technology transfer award for FDA.)
• Cash Award August 1999, for special act or service in recognition of Excellence in the Technology Transfer Area.
• Cash Award March 1998, for Special Accomplishment, reorganizing the Chemistry Program. From the Division Director, Division of Microbiology and Chemistry.
• Cash Award June 1998 , for Leadership as Team Leader, devoting time, skill, creativity and personal concern in being Team Leader for the Chemistry Staff. From the Deputy Director, NCTR.
• NCTR Government Employee of the Month, September 1998.
• Honor Student Commendation, DHHS Director, Office of Acquisition and Grants Management (Nov. 6, 1989).
• FDA, Commendable Service Award for development of vapor sampling analytical technologies (1992)
• FDA, Group Recognition Award , For exemplary dedication and interagency teamwork in the implementing a plan that addressed issues associated with the use of total parenteral nutrition.
• American Chemical Society, Central Arkansas Local Section Program Chairman (1989)
• American Chemical Society, Central Arkansas Local Section Chairman (1990)
• Oklahoma Academy of Science (1977)
• Phillips Petroleum Summer Fellow (1972)
• Phi Lambda Epsilon (1970)
• NSF Summer Research Associate (1967)

Current Primary Research Interests:

• Development of rapid test systems for the determination of food quality.
• Identifying and measurement of volatile flavors and off-flavors in food products.
• Computational and predictive Chemistry

Most Recent Publications:

• M. Lee, N. Takenaka, F.A. Beland and D.W. Miller*. "Using Direct Thermal Desorbtion to Assess the Potential Pool of Styrene and 4-Phenylcyclohexene." The Mass Spec Source, 10 (1994).

• E.D. Conte, S. Conway, D.W. Miller* and P.W. Perschbacher. "Determination of Methylisoborneol in Catfish Pond Water by Solid Phase Extraction Followed by Gas Chromatograph-Mass Spectrometry." Wat. Res. 30, 2125-2127 (1996).

• E.D. Conte, P.W. Perschbacher, C.Y. Shen and D.W. Miller. "Determination of Geosmin and Methylisoborneol in Catfish Tissue by Microwave Assisted Distillation-Solid Phase Absorbent Trapping." J. Agric. Food Chem. 44, 829-835 (1996).

• E.D. Conte, C. Shen, D.W. Miller and P.W. Perschbacher. "Microwave Distillation-Solid Phase Adsorbent Trapping Device for the Determination of Off-Flavors, geosmin and Methylisoborneol, in Catfish Tissue Below their Rejection Levels." Anal. Chem. 68, 2713-2716 (1996)

• E.D. Conte and D.W. Miller. "A Solid Phase Microextraction-Electrodeposition Device For The Determination of Putracine and Cadaverine by High Resolution GC." J. High Resolut. Chrom., 19, 293-297 (1996).

• PATENT D.W. Miller, J.G. Wilkes E.D. Conte, Food Quality Indicator Device. Provisional patent, US DOCKET number 11613.7USP1, JULY 17, 1997. International patent published Jan. 28, 1999, No. WO 99/04256.

• Jon G. Wilkes, Yongkyoung Kim, Dwight W. Miller, Manuel Holcomb, and Claire V. Nelson "Contamination of Food from Microwaving in Plastic Wrap Assessed by: (1) Distillation Purge-and-Trap GC/MS or (2) Probe/MS with Pattern Recognition" Proceedings of the 46th ASMS Conference on Mass Spectrometry and Allied Topics, Orlando, FL, May 30-June 4, 1998, 1486.

• D.W. Miller, E.D. Conte, C.Y. Shen and P.W. Perschbacher. "Colorimeteric Approach to Cyanobacterial Off-Flavor Detection." Wat. Sci. Tech. 40(6), 165-169 (1999)

• M. Zhu, F.J. Aviles, E.D. Conte, D.W. Miller and P.W. Perschbacher, "Microwave Mediated Distillation With Solid-Phase Microextraction Of Off-Flavors, Geosmin And Methylisoborneol, In Catfish Tissue". J. Chromatogr. A 833, 223-230 (1999).

• PATENT D.W. Miller, R. Beger, J.O. Lay, J.G. Wilkes and J.P. Freeman, "Methods for Predicting the Biological, Chemical, and Physical Properties of Molecules from their Spectral Properties." Provisional Patent filed July 31, 2000 Ref No. E-209-99/0

• Jon G. Wilkes, Eric D. Conte, Yongkyoung Kim, Manuel Holcomb, John B. Sutherland, and Dwight W. Miller "Sample Preparation for the analysis of off-flavors and flavors in foods" Invited Review in Journal of Chromatography A, 2000, 880, 3-33.

• Beger, R. D., Freeman, J. P., Lay, Jr., J. O., Wilkes, J. G., and Miller, D. W. Producing 13C NMR, Infrared Absorption and EI Mass Spectrometric Data Monodechlorination Models of Chlorobenzenes, Chlorophenols, and Chloroanilines J. Chem. Inf. Comput. Sci. in press.

• Beger, R. D., Freeman, J. P., Lay, Jr., J. O., Wilkes, J. G., and Miller, D. W. Producing 13C NMR, Infrared Absorption and EI Mass Spectrometric Data Monodechlorination Models of Chlorobenzenes, Chlorophenols, and Chloroanilines J. Chem. Inf. Comput. Sci. in press.

• Beger, R. D., Freeman, J. P., Lay, Jr., J. O., Wilkes, J. G., and Miller, D. W. 13C NMR and EI Mass Spectrometric Data to Produce a Predictive Model of Estrogen Receptor Binding Toxicol. Appl. Pharmacol., in press.

• Beger, R. D., Freeman, J. P., Lay, Jr., J. O., Wilkes, J. G., and Miller, D. W. The Use of 13C NMR Spectrometric Data to Produce a Predictive Model of Estrogen Receptor Binding Activity. J. Chem. Inf. Comput. Sci. in press.