Fort Valley State, Fort Valley, Georgia, B.S., 1977, Biology
Atlanta University, Atlanta, Georgia, M.S., 1979, Biology
Atlanta University, Atlanta, Georgia, Ph.D., 1981, Cell Biology

Experience:

• 1981-1983, Neurobiology Postdoctoral Fellow, Department of Biochemistry, University of North Carolina School of Medicine, Chapel Hill, NC.
• 1983-1984, Research Associate, Department of Biochemistry, University of North Carolina School of Medicine, Chapel Hill, NC.
• 1984-1985, Visiting Assistant Professor, Department of Biology, North Carolina Central University, Durham, NC.
• 1985-1988, Research Associate, Department of Pathology, Lineberger Cancer Research Center, University of North Carolina School of Medicine, Chapel Hill, NC.
• 1988-1997, Research Biologist, Division of Nutritional Toxicology, National Center for Toxicological Research, Jefferson, AR
• 1997-present, Senior Research Scientist, Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, AR

Honors:

• Award for Special Act or Service (for excellence on behalf of the 1999 Summer Student Program), NCTR, 2000
• Award for Special Act or Service (for extraordinary efforts in a multitude of research projects), NCTR, 1999
• Award for Teamwork/Collegiality, NCTR, 1997
• Award for Special Act or Service, NCTR, 1997
• Certificate of Appreciation, U.S. Department of Agriculture, Rural Economic and Community Development, 1996
• EPMS Outstanding Rating, 1996
• FDA Equal Opportunity Achievement Award, 1993
• Certificate of Appreciation, University of Arkansas at Little Rock, Devoted and Invaluable Services rendered to the Ronald E. McNair Program, 1992.
• Arkansas Federally Employed Woman of the Year (for professional achievement), 1992
• NCTR Woman of the Year award (for professional achievement), 1992
• EPMS Outstanding Rating, 1991
• Women in Medical Profession, Honoree, Pine Bluff Business and Professional Women, 1991
• EPMS Outstanding Rating, 1990
• VIPS Service Award, Pine Bluff Public Schools, 1990
• EPMS Outstanding Rating, 1989
• Outstanding Young Women of America, 1988
• Elected to the National Dean’s List, Atlanta University, 1981
• Recipient of the Most Outstanding Graduate Award, Atlanta University Center Biology Honor Society, 1981
• M.L. Reddick Award for Achievement in Cell Biology, Atlanta University, 1979
• Josiah Macy, Jr., Scholarship, Woods Hole, 1979
• MARC Predoctoral Fellowship, 1979-1981
• NSF Predoctoral Fellowship, 1979

Current Primary Research Interests: Cell and Molecular Epidemiology

• Develop in vitro assays using human cells to better understand mechanistic and toxic
  action of drugs
• Develop biomarkers associated with drug toxicity and carcinogenesis in human tissues
• Investigate dietary chemopreventive agents and their interaction with drug efficiency
• Investigate the role of epigenetic changes in metabolic genes with drug efficacy and carcinogenesis

Current Publications:

• Hammons, G.J., Yan-Sanders,Y., Jin, B. Blann, E, Kadlubar, F.F. and B.D. Lyn-Cook. 2000
  Specific Site Methylation in the 5’-Flanking Region of CYP1A2: Interdividual Differences in Human Liver. Submitted to Molecular Carcinogenesis.

• Hammons, G.J., Y. Yan, Lopatina, N.G., Jin, B., Wise, C., Blann, E.B., Poirier, L.A., Kadlubar, F.F., and B.D. Lyn-Cook. Increased expressed of hepatic DNA methyltransferase in smokers. Cell Biology and Toxicology 15(6):389-394, 1999.

• Lyn-Cook, B.D., Rogers, T., Yan, Y., Blann, E., Kadlubar, F.F., and Hammons, G.J. Chemoprotective Effects of Tea Extracts and Various Components on Human Pancreatic and Prostate Tumor Cells in Vitro. Nutrition and Cancer 35(1):78-84, 1999.

• Lyn-Cook, B.D., Stottman, H.L., Yan, Y., Blann, E. and Hammons, G.J. The Effects of Phytoestrogens on Human Pancreatic Tumor Cells In Vitro. Cancer Letters 142:111-119, 1999.

• Rao, P.S., Lyn-Cook, B.D., Littlefield, N.A. and Mehendale, H.M. High Glucose Concentration Alters Cell Proliferation Dynamics in Human Hepatoma Cells. International J. of Toxicology, 18:297-306, 1999.

• Hart, R.W., Bucci, T.J., Turturro, A., Leakey, J.E., Feuers, R.J., Duffy, P.H., James, S.J., Lyn-Cook, B.D., Pipkin, J.L, and Li, S. Caloric Intake as a Modulator of Carcinogenicity and Anticarcinogenicity. In: Carcinogenic/Anticarcinogenic Factors (Book Chapter), 1999.

• Tang, Y.M., Green, B.L., Chen, G., Thompson-carino, P., Lang, N.P. , Shinde, A., Lin, D., Lyn-Cook, B.D., Hammons, G.F., Kadlubar, F.F. Human CYP1B1 Leu 432Val Gene Polymorphism: Ethnic Distribution in African-Americans, Caucasians and Chinese: Estradiol Hydroxylase Activity and Distribution in Prostate Cancer Cases and Controls. Pharmcogenetics (In Press), 1999.

• Littlefield, N.A., Sheldon, W.G., Lyn-Cook, B.D. and B.S. Hass, The Effects of Dietary Magnesium on the Transformation Process in Mice. Trace Elements in Man and Animals. 9:183-185, 1997.

• Dalu, A., Cronin, G.M., Lyn-Cook, B.D., and Mehendale, H.M. Age-Related Differences in TGF-A and Proto-oncogenes Expression in Rat Liver After a Low Dose of Carbon Tetrachloride. J. Biochem Toxicology 10(5):259-264. 1995

• Hammons, G.J., Warren, G.J., Blann, E., Nichols, J., and Lyn-Cook, B.D., Increased DT- Diaphorase Activity in Transformed and Tumorigenic Pancreatic Acinar Cells. Cancer Letters. 96:9-14. 1995.

• Lyn-Cook, B.D., Blann, E., Hass, B.S. and Hart, R.W., Oncogene Expression and Cellular Transformation: The Effects of Dietary Restriction. In: Dietary Restriction. Implications for the Design and Interpretation of Toxicity and Carcinogenicity Studies (R. Hart, D. Neuman, and R. Robertson, Eds.) ILSI Press, Washington, D.C., pp.271-278. 1995.