Rhona Borts describes the results of two new studies, which use entirely different approaches to show that recombination hotspots are determined not only by features of the local genome but also by sequences acting at a considerable distance both in cis and trans.
Repairing an ancestral human pseudogene by mutagenesis, or by the application of aminoglycosides to suppress the termination codon, a new study shows, can restore the production of retrocyclins, peptides that block HIV-1 entry into cells.
C. elegans Abl (ABL-1) inhibits the engulfment of apoptotic cells, a new study shows, via a newly defined pathway that includes the C. elegans homolog of the cytoskeletal regulator Abl-interactor.
The evolution of resistance to insecticides by mosquitoes is a major threat to ongoing malaria control programs and plans for global eradication. Andrew Read and colleagues explain how evolutionary theory suggests a practical solution.
The prion protein is infamous for its role in devastating neurological diseases, but its normal, physiological function has remained mysterious. Using the experimentally tractable zebrafish model, a new study reveals fresh clues to this puzzle.
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