CGAP       the Cancer Genome Anatomy Project
    CGAP HOW TO GenesChromosomesTissuesSAGEPathwaysTools  

Genes

Gene Tools

SNP Tools

Transcriptome Analysis

CGAP Data

Purchase CGAP Reagents

Related Links

Quick Links:

NCI Logo


Gene Info

Gene Information For:Hs. SDHB, Succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Sequence ID:NM_003000

Database Links

UniGeneEntrez GeneOMIMDTPSNPViewerAssembliesSNP500CancerRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p36.1-p35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 17217962 - 17253114

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4124737Full LengthBC007840succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam Motifs
NM_003000 NP_002991 P21912 EC 1.3.5.1  

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M32246 AAA35708 P21912 EC 1.3.5.1
U17248 AAA81167 P21912 EC 1.3.5.1
BC007840 AAH07840 P21912 EC 1.3.5.1
DQ403007 ABD77140 Q0QEY7  
D10245 BAA01089 P21912 EC 1.3.5.1
AK312056 BAG34992 B2R545  

Homologs (from HomoloGene)

Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SDHB NP_002991 R.norvegicus Sdhb 298596   XP_216558 92
M.musculus Sdhb 67680 Gene Info NP_075863 92
A.gambiae AgaP_AGAP007309 1269860   XP_308512 77
S.cerevisiae SDH2 850685   NP_013059 73
D.melanogaster SdhB 35590   NP_477101 70
S.pombe sdh2 2542842   NP_593530 70
N.crassa NCU00959.1 2706599   XP_325139 67
A.thaliana SDH2-2 834065   NP_198881 65
M.grisea MGG_00167 2674556   XP_369077 65
C.elegans sdhb-1 174482   NP_495992 64

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

Kegg Pathways
Pathway information courtesy of Kegg


If you have any questions, comments, or need information about CGAP, please contact the NCI CGAP Help Desk.