| PROPOSAL NUMBER: | 02- B5.01-7782 (For NASA Use Only - Chron: 024217 ) |
| SUBTOPIC TITLE: | Biomolecular Sensors and Effectors |
| PROPOSAL TITLE: | A Wireless Communications Platform for Implantable Microinstruments |
SMALL BUSINESS CONCERN
(Firm Name, Mail Address, City/State/Zip, Phone)
Integrated Sensing Systems, Inc. (ISSYS)
391 Airport Industrial Dr.
Ypsilanti , MI 48198 - 7812
(734 ) 547 - 9896
PRINCIPAL INVESTIGATOR/PROJECT MANAGER
(Name, E-mail, Mail Address, City/State/Zip, Phone)
Matthew Straayer
straayer@mems-issys.com
391 Airport Industrial Dr.
Ypsilanti , MI 48198 - 7812
(734 ) 547 - 9896
TECHNICAL ABSTRACT (LIMIT 200 WORDS)
The innovation proposed is a platform for wireless communication based on magnetic telemetry that enables implantable micro instruments without batteries to acquire instructions, sense physical and chemical parameters, perform basic signal processing and on-site conditioning, and communicate information over 15cm. The platform, including electronics hardware and a protocol for a wide range of sensing devices and interfaces, will couple with emerging micro technologies for biochemical and biophysical applications to provide long term, implantable solutions. This proposal is innovative because the expected performance gains of the batteryless technology would enable much smaller implant sizes, increased transmission distance, and longer lifetimes than what is currently available today for monitoring chemical or physical parameters internal to the human body. In addition, this platform is capable of bi-directional communication that could allow for actively responding to individual needs such as closed-loop drug delivery. The Phase I effort involves designing the overall system architecture, proving the technical feasibility, and developing a prototype circuit design. Phase II builds on this platform and increases flexibility by incorporating a number of features into the electronics that enable the compatibility of a wide variety of interfaces and flexible performance options.
POTENTIAL COMMERCIAL APPLICATIONS (LIMIT 150 WORDS)
? Implantable sensors for conducting medical research on biological pressures in animals and humans
? Hemodynamic monitors for aiding treatment of congestive heart failure patients
? Wireless implantable sensors for monitoring and aiding treatment of pulmonary hypertension patients
? Intracranial pressure / shunt monitors for treatment of hydrocephalus
? Intraocular pressure monitors for research of glaucoma diagnosis and treatment
? Closed loop drug delivery, such as glucose sensing and insulin delivery
? Oxygen sensors for dynamic pacemaker algorithms
POTENTIAL NASA APPLICATIONS (LIMIT 150 WORDS)
? Wireless telemetry communication for micro biochemical and physical instruments and sensors
? Miniaturization of instruments through integration with MEMS-based sensors
? In situ measurement and real time control of biological and physical phenomena
? Capability for automated acquisition, processing, and communication of biological data
? Miniature bioprocessing systems which allow for precise measurement and closed loop control of multiple environmental parameters such as temperature, pH, oxygen, etc.