Also called: Also called: Regional enteritis, Regional ileitis
Crohn's disease causes inflammation of the digestive system. It is one of a group of diseases called inflammatory bowel disease. The disease can affect any area from the mouth to the anus. It often affects the lower part of the small intestine called the ileum.
Crohn's disease seems to run in some families. It can occur in people of all age groups but is most often diagnosed in young adults. Common symptoms are pain in the abdomen and diarrhea. Bleeding from the rectum, weight loss, joint pain, skin problems and fever may also occur. Children with the disease may have growth problems. Other problems can include intestinal blockage and malnutrition.
Treatment may include medicines, nutrition supplements, surgery or a combination of these options. Some people have long periods of remission, when they are free of symptoms.
National Institute of Diabetes and Digestive and Kidney Diseases
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Crohn's Disease
(Patient Education Institute) - http://www.nlm.nih.gov/medlineplus/tutorials/crohnsdisease/htm/index.htm
Also available in Spanish http://www.nlm.nih.gov/medlineplus/spanish/tutorials/crohnsdiseasespanish/htm/index.htm -
What I Need to Know about Crohn's Disease
(National Digestive Diseases Information Clearinghouse) - http://digestive.niddk.nih.gov/ddiseases/pubs/crohns_ez/index.htm
- About Crohn's Disease(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/about/crohns
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Crohn's Disease(National Institute of Diabetes and Digestive and Kidney Diseases) - http://digestive.niddk.nih.gov/ddiseases/pubs/crohns/
- Crohn's Disease(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/crohns-disease/DS00104/METHOD=print&DSECTION=all
- Facts about Crohn's Disease(Food and Drug Administration) - http://www.fda.gov/consumer/updates/crohnsdisease011508.html
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Inflammatory Bowel Disease(American Academy of Family Physicians) - http://familydoctor.org/online/famdocen/home/common/digestive/disorders/252.printerview.html
Also available in Spanish http://familydoctor.org/online/famdoces/home/common/digestive/disorders/252.printerview.html
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JAMA Patient Page: Crohn Disease(American Medical Association) - Links to PDF - http://jama.ama-assn.org/cgi/reprint/299/14/1738.pdf
- Scientists Discover New Drug Targets for Crohn's Disease(02/26/2009, HealthDay) - http://www.nlm.nih.gov/medlineplus/news/fullstory_81092.html
- How IBD Is Diagnosed(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/about/diagnose
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Lower GI Series (Barium Enema)(National Institute of Diabetes and Digestive and Kidney Diseases) - http://digestive.niddk.nih.gov/ddiseases/pubs/lowergi/
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MedlinePlus: Colonoscopy(National Library of Medicine) - http://www.nlm.nih.gov/medlineplus/colonoscopy.html
Also available in Spanish http://www.nlm.nih.gov/medlineplus/spanish/colonoscopy.html
- Understanding Capsule Endoscopy(American Society for Gastrointestinal Endoscopy) - http://www.asge.org/PatientInfoIndex.aspx?id=390
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Upper GI Series(National Institute of Diabetes and Digestive and Kidney Diseases) - http://digestive.niddk.nih.gov/ddiseases/pubs/uppergi/
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Ileostomy, Colostomy and Ileoanal Reservoir Surgery(National Institute of Diabetes and Digestive and Kidney Diseases) - http://digestive.niddk.nih.gov/ddiseases/pubs/ileostomy/index.htm
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Living with Crohn's Disease: More Options for Treatment(National Institutes of Health) - http://newsinhealth.nih.gov/2008/March/docs/01features_02.htm
- Surgery for Crohn's Disease(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/surgery/surgerycd
- Types of Medications for Inflammatory Bowel Disease(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/treatment/medications
- Diet and Nutrition(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/diet?LMI=4.2
- Specific Carbohydrate Diet: Does It Work?(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/about/news/scd
- Crohn's Disease and Ulcerative Colitis: Emotional Factors(Crohn's & Colitis Foundation of America) - Links to PDF - http://www.ccfa.org/frameviewer/?url=/media/pdf/emotional.pdf
- Intimate Relationship of Sex and Inflammatory Bowel Disease(Crohn's & Colitis Foundation of America) - Links to PDF - http://www.ccfa.org/frameviewer/?url=/media/pdf/ibdsexuality.pdf
- Anal Abscess/Fistula(American Society of Colon and Rectal Surgeons) - http://www.fascrs.org/patients/conditions/anal_abscess_fistula/
- Crohn's Disease Symptom: Is Fatigue Common?(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/crohns-disease/AN01434/METHOD=print
- Crohn’s Disease and Ulcerative Colitis: Understanding Colorectal Cancer(Crohn's & Colitis Foundation of America) - Links to PDF - http://www.ccfa.org/frameviewer/?url=/media/pdf/cancer.pdf
- Inflammatory Bowel Disease (IBD) and Measles Vaccine - http://www.cdc.gov/vaccinesafety/concerns/archive/ibd_and_measles.htm
- Possible Complications of IBD(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/about/complications/
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Short Bowel Syndrome(National Institute of Diabetes and Digestive and Kidney Diseases) - http://digestive.niddk.nih.gov/ddiseases/pubs/shortbowel/index.htm
- Traveling with Inflammatory Bowel Disease (IBD)(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/living/travel
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What People with Inflammatory Bowel Disease Need to Know about Osteoporosis(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Osteoporosis/Conditions_Behaviors/inflammatory_bowel.asp
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Crohn's Disease(Patient Education Institute) - http://www.nlm.nih.gov/medlineplus/tutorials/crohnsdisease/htm/index.htm
Also available in Spanish http://www.nlm.nih.gov/medlineplus/spanish/tutorials/crohnsdiseasespanish/htm/index.htm
- Minimally Invasive Colon Surgery(OR-Live) - One hour program - 1/24/2007 - http://www.or-live.com/distributors/NLM/rnh.cfm?id=388
- Atlas of the Body: The Digestive System(American Medical Association) - http://www.medem.com/medlib/article/ZZZ7C4T46JC
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ClinicalTrials.gov: Crohn Disease(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Crohn+Disease%22
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ClinicalTrials.gov: Inflammatory Bowel Diseases(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Inflammatory+Bowel+Diseases%22
- Placebo Effect: What's Your Gut Feeling?(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/research/placebo
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Genetics Home Reference: Crohn disease(National Library of Medicine) - http://ghr.nlm.nih.gov/condition=crohndisease
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Learning about Crohn's Disease(National Human Genome Research Institute) - http://www.genome.gov/25521854
- New Developments in Basic IBD Research(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/about/news/trendsinbasicresearch
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Research Shows Promise of Pineapple Extract for Inflammatory Bowel Disease(National Center for Complementary and Alternative Medicine) - http://nccam.nih.gov/research/results/spotlight/070108.htm
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Crohn's disease, autophagy, and the Paneth cell. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=19369659&tool=MedlinePlus
- Article: Where are all the Mycobacterium avium subspecies paratuberculosis in patients... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=19325887&tool=MedlinePlus
- Article: Ileal pouch rectal anastomosis: a viable alternative to permanent ileostomy... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=19318001&tool=MedlinePlus
- Crohn's Disease -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=crohn+disease[majr]+AND+(jsubsetk[text]+OR+jsubsetn[text]+OR+jsubsetaim[text]+OR+review[pt]+OR+guideline[pt]+OR+clinical+trial[pt]+OR+patient+education+handout[pt]+OR+systematic[sb])+AND+humans[mh]+AND+english[la]+NOT(letter[pt]+OR+editorial[pt]+OR+case+reports[pt])&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus
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Digestive Diseases Dictionary(National Institute of Diabetes and Digestive and Kidney Diseases) - http://digestive.niddk.nih.gov/ddiseases/pubs/dictionary/
- Find a CCFA Physician Member(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/physician/?LMI=4.6
- GI Physician Locator(American College of Gastroenterology) - http://www.acg.gi.org/patients/phylocator.asp
- American Gastroenterological Association - http://www.gastro.org/
- American Society of Colon and Rectal Surgeons - http://www.fascrs.org/
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National Institute of Diabetes and Digestive and Kidney Diseases - http://www.niddk.nih.gov/
- Social Security: Applying for Benefits(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/living/disability/
- Guide for Parents(Crohn's & Colitis Foundation of America) - Links to PDF - http://www.ccfa.org/frameviewer/?url=/media/pdf/parentguide2005.pdf
- Guide for Teachers and Other School Personnel(Crohn's & Colitis Foundation of America) - Links to PDF - http://www.ccfa.org/frameviewer/?url=/media/pdf/teacherguide2005.pdf
- Inflammatory Bowel Disease(Nemours Foundation) - http://kidshealth.org/kid/health_problems/stomach/IBD.html
- Treating Children and Adolescents(Crohn's & Colitis Foundation of America) - http://www.ccfa.org/info/treatment/kidsmeds
- Inflammatory Bowel Disease(Nemours Foundation) - http://kidshealth.org/teen/diseases_conditions/digestive/ibd.html
- Teen Guide: Dealing with Crohn’s & Colitis(Crohn's & Colitis Foundation of America) - Large PDF file - http://www.ccfa.org/frameviewer/?url=/media/pdf/teensfinal.pdf
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Inflammatory Bowel Disease(National Women's Health Information Center) - http://womenshealth.gov/faq/inflammatory-bowel-disease.cfm
Also available in Spanish http://womenshealth.gov/espanol/preguntas/ibd.htm
- Pregnancy and IBD(Crohn's & Colitis Foundation of America) - Links to PDF - http://www.ccfa.org/media/pdf/FactSheets/pregnancy.pdf
- Colonic Diseases - http://www.nlm.nih.gov/medlineplus/colonicdiseases.html
- Ulcerative Colitis - http://www.nlm.nih.gov/medlineplus/ulcerativecolitis.html
- Digestive System - http://www.nlm.nih.gov/medlineplus/digestivesystem.html
The primary NIH organization for research on Crohn's Disease is the National Institute of Diabetes and Digestive and Kidney Diseases - http://www.niddk.nih.gov/
Crohn's Disease - Multiple Languages - http://www.nlm.nih.gov/medlineplus/languages/crohnsdisease.html