U.S. Food & Drug Administration
Center for Food Safety & Applied Nutrition

Bacteriological Analytical Manual Online
January 2003

M17a
Biosynth Chromogenic Medium (BCM) for Listeria monocytogenes

(Biosynth Chromogenic Medium (BCM) for Listeria monocytogenes is available commercially)

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The proprietary BCM Listeria monocytogenes Plating Medium contains a substrate for phosphotidylinositol-specific phospholipase C (PlcA) enzymes that differentiates L. monocytogenes and L. ivanovii from other Listeria species. It can be obtained commercially as a dehydrated basal medium plus supplements. Differential activity for all Listeria species is due to the addition of a chromogenic substrate. One source is Biosynth International, Inc., Naperville, IL.


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