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Significant Guidance Documents

The Office of Management and Budget (OMB) established guidelines federal agencies should follow when creating and disseminating important guidance (Bulletin No. 07-02). Part of these guidelines state that agencies must provide easy access to a list of all of an agency's significant guidance documents in electronic form on its Web site.

The Centers for Disease Control and Prevention (CDC) provides guidance products to the public and the federal community in fulfilling its mission. CDC is currently compiling a list of these documents and will shortly add these to this Web site. CDC will add any new significant guidance documents that it issues to this Web site within 30 days of their publication.


CDC's Significant Guidance* Documents

CDC has also developed and made available guidance documents and information related to Pandemic Flu, including information on Planning and Response.

CDC’s National Institute for Occupational Safety and Health makes available selected draft guidance and other documents for public review.


*OMB Bulletin No. 07-02 and Executive Order 13422 define a "significant guidance document as a guidance document disseminated to regulated entities or the general public that may reasonably be anticipated to do one or more of the following:

  1. lead to an annual effect of $100 million or more or adversely affect in a material way the economy, a sector of the economy, productivity, competition, jobs, the environment, public health or safety, or State, local, or tribal governments or communities;
  2. create a serious inconsistency or otherwise interfere with an action taken or planned by another agency;
  3. materially alter the budgetary impacts of entitlements, grants, user fees or loan programs or the rights or obligations of recipients thereof;
  4. raise novel legal or policy issues arising out of legal mandates, the President's priorities, or the principles set forth in this Executive Order.

For more information, you may read OMB Final Bulletin for Agency Good Guidance Practices. (PDF)


  • Links to non-federal organizations are provided solely as a service to our users. These links do not constitute an endorsement of these organizations or their programs by CDC or the federal government, and none should be inferred. CDC is not responsible for the content of the individual organization Web pages found at these links.
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