Treatment of Horizontal Canal Benign Paroxysmal Positional Vertigo - Full Text View

Treatment of Horizontal Canal Benign Paroxysmal Positional Vertigo (BPPV-HC)

This study is not yet open for participant recruitment.

Verified by Chonbuk National University, November 2008

Sponsored by:	Chonbuk National University
Information provided by:	Chonbuk National University
ClinicalTrials.gov Identifier:	NCT00810641

Purpose

The purpose of this study was to compare the immediate efficacies of each treatment maneuvers in treatment of horizontal canal benign paroxysmal positional vertigo (HC-BPPV).

Condition
Vertigo

MedlinePlus related topics: Dizziness and Vertigo

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Prospective
Official Title:	Randomized Multicenter Study of Treatment of Horizontal Canal Benign Paroxysmal Positional Vertigo

Further study details as provided by Chonbuk National University:

Estimated Enrollment:	100
Study Start Date:	December 2008
Estimated Study Completion Date:	April 2009
Estimated Primary Completion Date:	March 2009 (Final data collection date for primary outcome measure)

Groups/Cohorts
1 Geotropic HC-BPPV
2 Apogeotropic HC-BPPV

Detailed Description:

A randomized prospective study of patients with HC-BPPV. Patients with geotropic and apogeotropic type of HC-BPPV were randomized to one of each three treatment groups at their first clinic visit. These groups included the barbecue maneuver, Gufoni's maneuver, and a control group in geotropic HC-BPPV, and the head-shaking method, Gufoni's maneuver, and a control group in apogeotropic type. Responsiveness of treatment maneuver was determined by positioning maneuver immediately after each treatment method based on resolves of vertigo and positional nystagmus.

Eligibility

Ages Eligible for Study:	18 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

From December 2008, consecutive patients with geotropic and apogeotropic HC-BPPV will be recruited from nationwide seven Dizziness Clinics in Korea. This study will adopt a prospective randomized trial which consisted of two treatment arms and control group in each type of HC-BPPV. In geotropic HC BPPV, patients will be subjected to barbecue maneuver and Gufoni's maneuver and control group. In apogeotropic type, head-shaking method and Gufoni's method and control are included.

Criteria

Inclusion Criteria:

a history of brief episodes of positional vertigo,
direction-changing horizontal nystagmus beating toward the uppermost (apogeotropic nystagmus) or undermost (geotropic nystagmus) ear in both the lateral head turning positions,
no spontaneous nystagmus during upright sitting position, and
absence of identifiable central nervous system disorders that could explain the positional vertigo and nystagmus.

Exclusion Criteria:

central positional nystagmus with identifiable CNS lesions that could explain the positional nystagmus

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00810641

Contacts

Contact: Sun-Young Oh, Dr. PhD.

082-063-250-1590

ohsun@chonbuk.ac.kr

Sponsors and Collaborators

Chonbuk National University

More Information

Responsible Party:	Korean association of neuro-ophthalmology and neuro-otology ( KNONO )
Study ID Numbers:	KNONO
Study First Received:	December 17, 2008
Last Updated:	December 17, 2008
ClinicalTrials.gov Identifier:	NCT00810641
Health Authority:	Korea: Food and Drug Administration

Keywords provided by Chonbuk National University:

BPPV(benign paroxysmal positional vertigo)
HC-BPPV(BPPV involving the horizontal semicircular canal)
Nystagmus
Treatment outcome
Horizontal Canal Benign Paroxysmal Positional Vertigo

Study placed in the following topic categories:

Signs and Symptoms
Benign paroxysmal positional vertigo
Otorhinolaryngologic Diseases
Neurologic Manifestations

Vestibular Diseases
Ear Diseases
Vertigo
Nystagmus, Pathologic

Additional relevant MeSH terms:

Nervous System Diseases
Labyrinth Diseases

ClinicalTrials.gov processed this record on January 16, 2009