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Chylothorax Following Heart Surgery
This study has been terminated.
Sponsored by: Children's Healthcare of Atlanta
Information provided by: Children's Healthcare of Atlanta
ClinicalTrials.gov Identifier: NCT00215098
  Purpose

The purpose of this study is to determine at risk populations for certain congenital heart defects or certain operative procedures and to define the associated morbidity secondary to chylothorax - prolonged chest tube drainage, prolonged hospital stay, need for central access and hyperalimentation, subsequent infection.


Condition
Chylothorax

MedlinePlus related topics: Heart Surgery
U.S. FDA Resources
Study Type: Observational
Study Design: Natural History, Longitudinal, Defined Population, Retrospective Study
Official Title: Chylothorax in Children Following Congenital Heart Surgery

Further study details as provided by Children's Healthcare of Atlanta:

Estimated Enrollment: 70
Study Start Date: May 2005
Estimated Study Completion Date: November 2006
Detailed Description:

Chylothorax is not uncommon following congenital heart surgery. It often results in prolonged chest tube drainage and hospital stays. Due to the feeding difficulties, it often results in malnutrition and the need for central hyperalimentation. In addition, it results in a depressed immune system with the possibility of subsequent infection. Chylothorax can be a significant contributor to post-operative morbidity and mortality.

The primary aims are to determine at risk populations - certain congenital heart defects or certain operative procedures, to define the associated morbidity secondary to chylothorax - prolonged chest tube drainage, prolonged hospital stay, need for central access and hyperalimentation, subsequent infection and to review our current treatment methods - change formulas, hyperalimentation, somatostatin. The secondary aims are to determine ways to prevent chylothorax, determine the most successful treatment method, and to discover better treatment methods. This study will be conducted through a retrospective chart review.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Patients in the congenital surgery database
  • patients have developed post-operative chylous effusions

Exclusion Criteria:

-

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00215098

Locations
United States, Georgia
Children's Healthcare of Atlanta at Egleston
Atlanta, Georgia, United States, 30322
Sponsors and Collaborators
Children's Healthcare of Atlanta
Investigators
Principal Investigator: Brian Kogon, MD Emory University
  More Information

Study ID Numbers: 05-093
Study First Received: September 20, 2005
Last Updated: June 12, 2007
ClinicalTrials.gov Identifier: NCT00215098  
Health Authority: United States: Food and Drug Administration

Keywords provided by Children's Healthcare of Atlanta:
pediatric health
cardiac
congenital heart surgery
post-operative chylous effusions
heart defects
children

Study placed in the following topic categories:
Respiratory Tract Diseases
Pleural Diseases
Chylothorax

ClinicalTrials.gov processed this record on January 16, 2009