Welcome to the NIH Genetic Modification Clinical Research Information System (GeMCRIS®). GeMCRIS is a comprehensive information resource and analytical tool for scientists, research participants, institutional oversight committees, sponsors, federal officials, and others with an interest in human gene transfer research. GeMCRIS allows users to access an array of information about human gene transfer trials registered with the NIH, including medical conditions under study, institutions where trials are being conducted, investigators carrying out these trials, gene products being used, route of gene product delivery, and summaries of study protocols. To facilitate access to this information, GeMCRIS offers a number of preformatted reports. You can also create your own query tailored to your particular information needs. To get started, use the "Search" menu item above, or click the "Frequently Asked Questions" link on the left to learn more about using the system. We are seeking comments on GeMCRIS's utility and ease of use. Please take a moment to respond to the questions on the form provided through the "Feedback" link on this page. Your input is critical to ensuring that the system meets the needs of all its diverse users.