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IRIS Toxicological Review of Halogenated Platinum Salts and Platinum Compounds (External Review Draft)

Federal Register Notices
Contact
Andrew Rooney
by phone at:   919-541-1492
by email at:  rooney.andrew@epa.gov
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Notice

[4/27/09] EPA announced an external peer review workshop for the draft review report to be held on May 21st in Washington, DC.

[2/5/09] EPA announces the release of the Toxicological Review of Halogenated Platinum Salts and Platinum Compounds in the Feb 5, 2009 Federal Register Notice. This draft assessment is provided for public viewing and comment. Public comments received on the Toxicological Review within 60 days after the release of the FRN will be provided to the external peer reviewers for their consideration. Any comments not received within the requested time period will be considered by EPA in their revisions. The date and location of the external peer review meeting will be provided in a separate announcement.

EPA conducted a peer review of the scientific basis supporting the human health hazard and dose-response assessment of halogenated platinum salts and platinum compounds that will appear in the Integrated Risk Information System (IRIS) database.
Background
The draft Toxicological Review of Halogenated Platinum Salts and Platinum Compounds provides scientific support and rationale for the hazard and dose-response assessment pertaining to chronic exposure to Halogenated Platinum Salts and Platinum Compounds. The two major uses of Pt compounds are in jewelry and in automotive emission control catalysts (catalytic converters). Evidence suggests that vehicles equipped with catalytic converters represent a significant source of Pt in ambient air, especially in areas heavily populated with automotive vehicles. Use of Pt compounds as fuel-borne catalysts in diesel fuel vehicles presents another potential source of environmental Pt.

This assessment contains the derivation of a chronic reference concentration.

History/Chronology

2005The IRIS assessment of Halogenated Platinum Salts and Platinum Compounds was initiated in 2005.
Feb 2009EPA released an updated external review draft for public review and comment.
Mar 2009EPA announced a public listening session for the draft review report.
Apr 2009EPA announced an external peer review workshop for the draft review report to be held on May 21st in Washington, DC.
Jul 2009EPA releases the comments from the public comment period and external review workshop.

Next Steps

Following the External Peer Review, the final assessment will be published on the IRIS database. Previously, an assessment for Halogenated Platinum Salts and Platinum Compounds is not currently in IRIS.

Downloads/Related Links

This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.

Additional Information

Comments on the assessment may be submitted and reviewed using the e-Government Regulations.gov Web site. From the site, select Environmental Protection Agency and the keyword EPA-HQ-ORD-2009-0040 (for the docket ID) to comment on this report.

Citation

U.S. EPA. IRIS Toxicological Review of Halogenated Platinum Salts and Platinum Compounds (External Review Draft). EPA/635/R-08/018, 2009.
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