Note: This guideline has been updated. The National Guideline Clearinghouse (NGC) is working to update this summary. The recommendations that follow are based on the previous version of the guideline.
ACR Appropriateness Criteria®
Clinical Condition: Premature Cervical Dilatation
Variant 1: Patient not at risk for preterm delivery: 18 weeks gestation: by transabdominal scan cervix < 2.5 cm long.
Radiologic Exam Procedure |
Appropriateness Rating |
Comments |
Ultrasound |
Report specific cervical length in mm or cm |
9 |
|
Transabdominal followed by translabial or transvaginal |
8 |
|
Multiple looks at cervix during US exam |
8 |
|
Report endocervical diameter in mm (if dilated) |
8 |
|
Transabdominal scan only - bladder full |
2 |
|
Transabdominal scan only - bladder empty |
2 |
|
Single look at cervix during US exam |
2 |
|
Sonographic cervical stress test |
No Consensus |
May identify patients requiring treatment for preterm cervical dilation. See the summary below. |
Appropriateness Criteria Scale
1 2 3 4 5 6 7 8 9
1 = Least appropriate 9 = Most appropriate
|
Note: Abbreviations used in the tables are listed at the end of the "Major Recommendations" field.
Variant 2: Patient at risk for preterm delivery (history of 3 prior mid-trimester spontaneous losses): 18 weeks gestation: by transabdominal scan cervix < 3.8 cm long.
Radiologic Exam Procedure |
Appropriateness Rating |
Comments |
Ultrasound |
Report specific cervical length in mm or cm |
9 |
|
Multiple looks at cervix during US exam |
8 |
|
Report endocervical diameter in mm (if dilated) |
8 |
|
Transabdominal scan only - bladder empty |
6 |
|
Transabdominal followed by translabial or transvaginal |
6 |
|
Transabdominal scan only - bladder full |
2 |
|
Single look at cervix during US exam |
2 |
|
Sonographic cervical stress test |
No Consensus |
May identify patients requiring treatment for preterm cervical dilation. See the summary below. |
Appropriateness Criteria Scale
1 2 3 4 5 6 7 8 9
1 = Least appropriate 9 = Most appropriate
|
Note: Abbreviations used in the tables are listed at the end of the "Major Recommendations" field.
Variant 3: Patient at no risk for preterm delivery: 18 weeks gestation: by transabdominal scan cervix <3.8 cm long.
Radiologic Exam Procedure |
Appropriateness Rating |
Comments |
Ultrasound |
Transabdominal scan only |
8 |
|
Single look at cervix during US exam |
8 |
|
Report endocervical diameter in mm (if dilated) |
8 |
|
Transabdominal followed by translabial or transvaginal |
2 |
|
Sonographic cervical stress test |
2 |
|
Multiple looks at cervix during US exam |
2 |
|
Report specific cervical length in mm or cm |
2 |
|
Appropriateness Criteria Scale
1 2 3 4 5 6 7 8 9
1 = Least appropriate 9 = Most appropriate
|
Note: Abbreviations used in the tables are listed at the end of the "Major Recommendations" field.
Variant 4: Patient not at risk for preterm delivery: 28 weeks gestation: by transabdominal scan cervix < 2.5 cm long.
Radiologic Exam Procedure |
Appropriateness Rating |
Comments |
Ultrasound |
Report specific cervical length in mm or cm |
9 |
|
Transabdominal followed by translabial or transvaginal |
8 |
|
Multiple looks at cervix during US exam |
8 |
|
Report endocervical diameter in mm (if dilated) |
8 |
|
Transabdominal scan only - bladder full |
2 |
|
Transabdominal scan only - bladder empty |
2 |
|
Single look at cervix during US exam |
2 |
|
Sonographic cervical stress test |
No Consensus |
May identify patients requiring treatment for preterm cervical dilation. See the summary below. |
Appropriateness Criteria Scale
1 2 3 4 5 6 7 8 9
1 = Least appropriate 9 = Most appropriate
|
Note: Abbreviations used in the tables are listed at the end of the "Major Recommendations" field.
Variant 5: Patient at risk for preterm delivery (history of 3 prior mid-trimester spontaneous loses): 28 weeks gestation: by transabdominal scan cervix <3.8 cm long.
Radiologic Exam Procedure |
Appropriateness Rating |
Comments |
Ultrasound |
Report specific cervical length in mm or cm |
9 |
|
Multiple looks at cervix during US exam |
8 |
|
Report endocervical diameter in mm (if dilated). |
8 |
|
Transabdominal scan only - bladder empty |
6 |
|
Transabdominal followed by translabial or transvaginal |
6 |
|
Transabdominal scan only - bladder full |
2 |
|
Single look at cervix during US exam |
2 |
|
Sonographic cervical stress test |
No Consensus |
May identify patients requiring treatment for preterm cervical dilation. See the summary below. |
Appropriateness Criteria Scale
1 2 3 4 5 6 7 8 9
1 = Least appropriate 9 = Most appropriate
|
Note: Abbreviations used in the tables are listed at the end of the "Major Recommendations" field.
Variant 6: Patient at no risk for preterm delivery: 28 weeks gestation: by transabdominal scan cervix <3.8 cm long.
Radiologic Exam Procedure |
Appropriateness Rating |
Comments |
Ultrasound |
Transabdominal scan only |
8 |
|
Single look at cervix during US exam |
8 |
|
Report endocervical diameter in mm (if dilated) |
8 |
|
Transabdominal followed by translabial or transvaginal |
2 |
|
Sonographic cervical stress test |
2 |
|
Multiple looks at cervix during US exam |
2 |
|
Report specific cervical length in mm or cm |
2 |
|
Appropriateness Criteria Scale
1 2 3 4 5 6 7 8 9
1 = Least appropriate 9 = Most appropriate
|
Note: Abbreviations used in the tables are listed at the end of the "Major Recommendations" field.
The term cervical incompetence was first introduced in 1948. This condition, which is characterized by painless midtrimester cervical dilatation, has a reported incidence of 1% and may be responsible for as many as 20% of second trimester miscarriages.
As a result of recent investigations that recognize features shared by women with cervical incompetence and those with premature labor, the concept of cervical incompetence as an "all or none" phenomenon has been challenged. Cervical incompetence is believed to represent a continuum that relates to cervical length and pregnancy history.
Regardless of the precise definition for this condition, there is no debate that preterm birth (<37 weeks of gestation) continues as the leading cause of perinatal morbidity and mortality. Consequently, it remains a major obstetrical challenge. Various methods for diagnosing preterm cervical dilatation have been proposed.
Digital Examination
Initial assessment is usually clinical and is based on digital palpation of the cervix. This examination can detect changes in cervical texture such as softening (which occurs as a precursor to delivery), and it can appreciate distensibility of the external os. These findings occur relatively late in the process of cervical dilatation, however, and in some cases are found too late to be reversed. Further, some physicians question the accuracy of digital measurements, which consistently underestimate measurements made by translabial or transvaginal ultrasound. Most likely, this inaccuracy is due to the anatomic configuration of the cervix because the portion of cervix that lies above the anterior fornix or above the bladder base is hidden from the examiner's fingers. The digital examination has other limitations: 1) it is a subjective assessment; 2) the internal cervical os, which reflects initial changes associated with premature cervical dilatation, is beyond the examiner's reach; and 3) there are potential side effects that include risk of infection and ruptured membranes.
Nonetheless, if a patient is clinically at risk for preterm delivery, or if the ultrasound examination detects a short cervical length, some obstetrician-gynecologists may perform a digital cervical examination. If she is near term (>37 weeks), however, this examination can be omitted, unless clinically indicated for other reasons. To optimize the results and patient management, it is important to correlate the findings of the ultrasound examination with the digital examination.
Sonographic Examination
Unlike digital examination, sonographic measurement of cervical length generates an image that may be reviewed and standardized, thus overcoming subjectivity.
Normal appearing cervix: During pregnancy, the length of the cervix does not elongate appreciably. Most authorities consider 3.0 cm in length as the lower limit of normal. In one large prospective, multicenter study, 4.0 cm was reported as the 75th percentile, 3.5 cm as the 50th percentile, 3.0 cm as the 25th percentile, and 2.6 as the 10th percentile.
Transabdominal evaluation: Because most obstetrical sonographic examinations are done transabdominally, this method remains the most common, even though it is the least reliable imaging method for evaluating the cervix. Using this approach, bladder overdistension can compress the walls of the lower uterine segment and cervix, creating a deceivingly normal appearance in women with cervical effacement, shortening, or frank dilatation. Furthermore, an underdistended bladder may preclude adequate cervical visualization for any one of a variety of reasons: acoustic shadowing from the pubic symphysis, refractive shadowing from the bladder-uterine interface, and loss of the acoustic window provided by the urinary bladder and/or amniotic fluid, or an inability to elevate the fetal head or other presenting part. Even when visible on a transabdominal scan, the cervical image is usually suboptimal. Because the external os is often not clearly identified, a technically correct cervical length measurement may not be possible. Aside from women near term (>37 weeks), if a patient has a clinical history or sonographic findings suspicious for cervical pathology, consideration should be given to additional scanning using either a transperineal or transvaginal approach. Rarely, in an at-risk patient, the entire cervix is clearly visible on a technically adequate transabdominal examination, in which case the translabial/transvaginal scan may be omitted. If a patient is not at risk, and has a normal-appearing cervix on transabdominal scans (with an empty or minimally filled bladder), it is not necessary to proceed to translabial/transvaginal imaging.
Translabial/transvaginal evaluation: These approaches are the most accurate for assessing the cervix. Cervical length is determined as the distance between the internal and external os. The internal os is normally at the level where the cervical canal meets the amniotic sac. The external os is often more difficult to precisely define because of acoustic shadowing from rectal gas. This problem can be minimized by either scanning the patient in a lateral decubitus position or elevating the hips and buttocks on a thick pad or pillow.
In patients at risk for cervical shortening or incompetence, some investigators suggest performing a cervical "stress test" by either applying transfundal pressure while scanning transvaginally, or by examining the patient while she is standing. Because some patients will initially have a completely normal-appearing cervix, these important maneuvers may identify additional women who may require treatment for preterm cervical dilatation. If the cervix is already dilated or short, the cervical stress test may not be necessary because it may compound the problem by inducing further dilatation and shortening.
Abnormal-appearing cervix: Although the clinical presentation varies, from an imager's point of view cervical changes are essentially identical in patients in term labor, preterm labor, or cervical incompetence. In each of these clinical situations, cervical dilatation begins proximally, at the level of the internal os, and progresses distally. As the internal os dilates, membranes and amniotic fluid invaginate into the proximal endocervical canal. The most accepted terminology for these changes is funneling, although wedging or beaking have also been used. Eventually the entire endocervical canal becomes filled with fluid, and if the membranes remain intact, they may be visible bulging into the vagina. Concurrent with dilatation, the cervix becomes effaced and shortened. Dilatation and effacement typically progress simultaneously, although, in a given patient, one or the other event may appear to predominate. In fact, in a series of patients with short cervices (<2.5 cm in length), funneling correlated with earlier delivery as well as higher neonatal mortality and morbidity.
Investigators have recommended quantitating these cervical changes using a variety of measuring techniques, but the simplest and most reproducible measurement in sensitivity and predictive value appears to be the residual closed length of the cervix. This calculation, which takes into account both dilatation and effacement, can be obtained by measuring from the distal apex of endocervical funneling at the internal os to the external os. Analysis supports 3.0 cm as the optimal cutoff to maximize sensitivity and specificity for predicting premature delivery. One investigation showed that all 24 subjects who delivered prematurely had a cervical length of less than 3.0 cm, and none of 15 women who had a cervical length of at least 3.0 cm delivered spontaneously before 36 weeks.
If a woman is clinically at risk for preterm delivery, or if a short cervix is detected by sonography, the precise length of the cervix should be measured and reported (this measurement is usually based on translabial or transvaginal scans). Studies have shown that serial transvaginal surveillance of cervical length in patients followed by cervical cerclage when cervical changes are encountered appears to reduce the cerclage rate without compromising pregnancy outcome. In addition, in cases with visible dilatation, sonologists should report the maximal endocervical diameter. The percent of "effacement" based on sonographic images is not reliable, because it is not possible to determine the location of the internal os once dilatation becomes apparent.
Pitfalls: A false diagnosis of preterm cervical dilatation may be made on a transabdominal scan in a patient who has a resolving lower uterine segment contraction, or whose cervix is vertically oriented (typically with a nondistended maternal bladder), and lacks prominent endocervical mucus. Under these circumstances, the glandular tissue circumferentially surrounding the endocervical canal can appear quite sonolucent and mimic endocervical fluid. These false positive errors can be avoided if a patient with suspicious findings on transabdominal images is reevaluated using a translabial or transvaginal approach. A false diagnosis of preterm cervical shortening may occur on a translabial scan if rectal gas obscured the external os.
False negative diagnoses can occur during transperineal or transvaginal scanning if a cervical stress test is omitted. One of the most challenging groups of patients to evaluate are those in whom the appearance of the cervix changes during the sonographic examination. These transient but important observations underscore the need to observe the appearance of the cervix several times during a single obstetrical sonographic study, and suggest that a single image of the cervix may be insufficient for thorough cervical evaluation. This is particularly the case in women at-risk for preterm delivery, or those in whom a short cervix is detected by sonography. When a woman has transitory cervical changes, the minimal length of residual cervix should be reported and the patient should be considered at risk. Clinical follow-up of these women reveals that 61% to 74% have preterm labor or deliver prematurely.
Conclusion
Translabial and transvaginal sonography can each provide unique information about the cervix, that otherwise might not be readily available. These examinations are easy to perform, and in the appropriate clinical setting, should become an integral part of the sonographic study.
Abbreviations