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Propyleneimine (CASRN 75-55-8)

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0621

Propyleneimine; CASRN 75-55-8

Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of chronic toxicity data by U.S. EPA health scientists from several Program Offices and the Office of Research and Development. The summaries presented in Sections I and II represent a consensus reached in the review process. Background information and explanations of the methods used to derive the values given in IRIS are provided in the Background Documents.

STATUS OF DATA FOR Propyleneimine

File First On-Line 01/01/1992

Category (section)
Status
Last Revised
Oral RfD Assessment (I.A.) no data  
Inhalation RfC Assessment (I.B.) message 01/01/1992
Carcinogenicity Assessment (II.) no data  

_I.  Chronic Health Hazard Assessments for Noncarcinogenic Effects

_I.A. Reference Dose for Chronic Oral Exposure (RfD)

Substance Name — Propyleneimine
CASRN — 75-55-8

Not available at this time.

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_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)

Substance Name — Propyleneimine
CASRN — 75-55-8

The health effects data for propyleneimine were reviewed by the U.S. EPA RfD/RfC Work Group and determined to be inadequate for derivation of an inhalation RfC. The verification status of this chemical is currently not verifiable. There are currently no EPA documents available for this chemical.

Agency Work Group Review — 11/07/1991

Screening-Level Literature Review Findings — A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the RfC for Propyleneimine conducted in September 2002 did not identify any critical new studies. IRIS users who know of important new studies may provide that information to the IRIS Hotline at hotline.iris@epa.gov or (202)566-1676.

EPA Contacts:

Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).

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_II.  Carcinogenicity Assessment for Lifetime Exposure

Substance Name — Propyleneimine
CASRN — 75-55-8

This substance/agent has not undergone a complete evaluation and determination under US EPA's IRIS program for evidence of human carcinogenic potential.

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_III.  [reserved]
_IV.  [reserved]
_V.  [reserved]


_VI.  Bibliography

Substance Name — Propyleneimine
CASRN — 75-55-8
Last Revised — 01/01/1992

_VI.A. Oral RfD References

None

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_VI.B. Inhalation RfC References

None available

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_VI.C. Carcinogenicity Assessment References

None

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_VII.  Revision History

Substance Name — Propyleneimine
CASRN — 75-55-8

Date
Section
Description
12/01/1991 I.B. Inhalation RfC now under review
01/01/1992 I.B. Inhalation RfC message on-line
01/01/1992 VI. Bibliography on-line; no inhalation refs available
04/01/1997 III., IV., V. Bibliography on-line; no inhalation refs available Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information.
12/03/2002 I.B. Screening-Level Literature Review Findings message has been added.

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_VIII.  Synonyms

Substance Name — Propyleneimine
CASRN — 75-55-8
Last Revised — 01/01/1992

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