Developmental Glycobiology Unit, LCDB 
NATIONAL INSTITUTES OF HEALTH/NIDCR
BUILDING 30, ROOM 4A400B1
30 CONVENT DR, MSC 4370
BETHESDA, MD 20892-4370
Phone: (301) 451-6318
Fax: (301) 402-0897
E-mail: Dr. Kelly Ten Hagen
Research Interests
Role of O-glycosylation during eukaryotic development; mucin-type O-linked glycosylation; O-glycans in Drosophila development; cell adhesion, signaling, and migration; and identification of in vivo substrates destined to be glycosylated.
Education
1986: BS, Cornell University, Ithaca, NY
1992: PhD, Stanford University, Stanford, CA
Recent publications
Ten Hagen, K.G. and Tran, D.T. A UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is essential for viability in Drosophila melanogaster. J. Biol. Chem. 277: 22616-22622, 2002.
Ten Hagen, K.G., Fritz, T.A., and Tabak, L.A. All in the family: the UDP-GalNAc : polypeptide N-acetylgalactosaminyltransferases. Glycobiol. 13: 1R-16R, 2003.
Young, W.W., Holcomb, D.R., Ten Hagen, K.G., and Tabak, L.A. Expression of UDP-GaINAc : polypeptide N-acetylgalactosaminyltransferase isoforms in murine tissues determined by real-time PCR: a new view of a large family. Glycobiol. 13: 549-557, 2003.
Ten Hagen, K.G., Tran, D.T., Gerken, T.A., Stein, D.S., and Zhang, Z. Functional characterization and expression analysis of members of the UDP-GalNAc : polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster. J. Biol. Chem. 278: 35039-35048, 2003.
Hang, H.C., Yu, C., Ten Hagen, K.G., Tian, E., Winans, K.A., Tabak, L.A., and Bertozzi, C.R. Small molecule inhibitors of mucin-type O-linked glycosylation from a uridine-based library. Chemistry & Biology. 11: 337-345, 2004.
Pratt, M.R., Hang, H.C., Ten Hagen, K.G., Rarick, J., Gerken, T.A., Tabak, L.A., and Bertozzi, C.R. Deconvoluting the functions of polypeptide N-±-acetylgalactosminyltransferase family members by glycopeptide substrate profiling. Chemistry & Biology. 11: 1009-1016, 2004.
Muller, R., Hulsmeier, A.J., Altmann, F., Ten Hagen, K.G., Tiemeyer, M., and Hennet, T. Characterization of mucin-type core-1 ¾1-3 galactosyltransferase homologous enzymes in Drosophila melanogaster. FEBS Journal. 272: 4295-4305, 2005.
Tian, E and Ten Hagen, K.G. Expression of the UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase family is spatially and temporally regulated during Drosophila development. Glycobiol. 16: 83-95, 2006.
Tian, E and Ten Hagen, K.G. A UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase is required for epithelial tube formation. J. Bio. Chem. 282: 606-614, 2007.
Tian, E and Ten Hagen, K.G. O-linked glycan expression during Drosophila development. Glycobiol. 17: 820-827, 2007.
Complete CV and Publications