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anti-PSCA fully human monoclonal antibody MK4721 An IgG1k fully human monoclonal antibody directed against the human prostate stem cell antigen (PSCA) with potential antineoplastic activity. Anti-PSCA fully human monoclonal antibody MK4721 selectively targets and binds to PSCA, triggering complement-dependent cell lysis and antibody-dependent cell-mediated cytotoxicity in tumor cells expressing PSCA. PSCA is a glycosyl-phosphatidylinositol (GPI)-linked cell surface antigen found in cancers of the bladder, pancreas, and prostate. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
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Code name: | ![](https://webarchive.library.unt.edu/eot2008/20090511131148im_/http://www.cancer.gov/images/spacer.gif) | AGS-PSCA | | ![](https://webarchive.library.unt.edu/eot2008/20090511131148im_/http://www.cancer.gov/images/spacer.gif) |
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