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autologous heat-shock protein 70 peptide vaccine AG-858 A recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. HSP70 associates with antigenic peptides, transporting them into antigen presenting cells (APC) for processing. Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Code name: | | AG-858 | | |
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