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Table 3. Criteria for Grading Severity of Nausea and Vomiting
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Grade 1
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Grade 2
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Grade 3
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Grade 4
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Grade 5
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Adapted from Cancer Therapy Evaluation Program, Common Terminology Criteria for Adverse Events, Version 3.0, DCTD, NCI, NIH, DHHS.
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Nausea |
Loss of appetite without alteration in eating habits |
Oral intake decreased without significant weight loss, dehydration or malnutrition; IV fluids indicated <24 h |
Inadequate oral caloric or fluid intake; IV fluids, tube feedings, or TPN indicated ≥24 h |
Life-threatening consequences |
Death |
Vomiting |
1 episode in 24 h |
2–5 episodes in 24 h; IV fluids indicated <24 h |
≥6 episodes in 24 h; IV fluids, or TPN indicated ≥24 h |
Life-threatening consequences |
Death |
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