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Found 156 studies with search of: "Ezetimibe"
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Rank Status Study
1 Completed Comparison of Ezetimibe Plus Simvastatin Versus Ezetimibe or Simvastatin Alone in Subjects With Primary Hypercholesterolemia (Study P03757)(COMPLETED)
Condition: Hypercholesterolemia
Interventions: Drug: Ezetimibe + Simvastatin;   Drug: Simvastatin;   Drug: Ezetimibe
2 Completed Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects
Conditions: Pharmacokinetics;   Drug Interactions;   Hypercholesterolemia;   Immunosuppression
Interventions: Drug: 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany;   Drug: 1 capsule Prograf(R) (tacrolimus), Astellas Pharma GmbH, Germany;   Drug: 1 tablet Ezetrol(R) + 1 capsules Prograf(R)
3 Completed Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects
Conditions: Pharmacokinetics;   Drug Interactions;   Hypercholesterolemia;   Immunosuppression
Interventions: Drug: 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany;   Drug: 1 tablet Rapamune(R) (sirolimus), Wyeth Pharma, Germany;   Drug: 1 tablet Ezetrol(R) + 1 tablet Rapamune(R)
4 Completed Assessment of Potential Interaction Between Ezetimibe and Rosuvastatin in Healthy Subjects With High Cholesterol (P03317)(COMPLETED)
Conditions: Hypercholesterolemia;   Atherosclerosis
Interventions: Drug: Ezetimibe + Rosuvastatin;   Drug: Rosuvastatin;   Drug: Placebo;   Drug: Ezetimibe
5 Completed Efficacy of TAK-475 Alone and With Ezetimibe in Subjects With Primary Dyslipidemia.
Condition: Hypercholesterolemia
Interventions: Drug: Lapaquistat;   Drug: Lapaquistat and ezetimibe;   Drug: Ezetimibe
6 Not yet recruiting Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-Lowering Ezetimibe and the Non-Nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2
Conditions: Pharmacokinetics;   Drug Interactions;   Pharmacodynamics;   Intestinal Transporter Expression
Interventions: Drug: 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany;   Drug: 1 tablet Ezetrol(R) + 2 capsules Sustiva(R) (efavirenz) single dose, DuPont Pharma;   Drug: tablet Ezetrol(R) and 2 capsules Sustiva(R) steady state
7 Completed Evaluation of Low-Density Lipoprotein (LDL) Cholesterol Levels in Patients Switched From Zetia 10 Milligrams to 5 Milligrams
Condition: Hypercholesterolemia
Interventions: Drug: Ezetimibe 10 mg;   Drug: Ezetimibe 5 mg
8 Enrolling by invitation A 12-Week Post-Marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-Lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)
Conditions: Hypercholesterolemia;   Familial Hypercholesterolemia;   Homozygous Sitosterolemia
Interventions: Drug: Ezetimibe;   Drug: Ezetimibe + other lipid-lowering medication(s)
9 Active, not recruiting A 52-Week Post-Marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-Lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)
Conditions: Hypercholesterolemia;   Familial Hypercholesterolemia;   Homozygous Sitosterolemia
Interventions: Drug: Ezetimibe;   Drug: Ezetimibe + other lipid-lowering medication(s)
10 Recruiting A Study of Ezetimibe Added On to Rosuvastatin Versus Up Titration of Rosuvastatin in Patients With Hypercholesterolemia
Condition: Hypercholesterolemia
Interventions: Drug: Comparator: rosuvastatin 5 mg + ezetimibe 10 mg;   Drug: Comparator: rosuvastatin 10 mg;   Drug: Comparator: rosuvastatin 10 mg + ezetimibe 10 mg;   Drug: Comparator: rosuvastatin 20 mg
11 Completed Effectiveness and Safety of Ezetimibe Added to Atorvastatin in Patients With High Cholesterol and Coronary Heart Disease (Study P03740)(COMPLETED)
Conditions: Hypercholesterolemia;   Coronary Heart Disease
Interventions: Drug: ezetimibe;   Drug: placebo
12 Completed To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia
Condition: Hypercholesterolemia
Interventions: Drug: Comparator: ezetimibe/simvastatin + niacin (ER);   Drug: Comparator: Placebo to ezetimibe/simvastatin;   Drug: Comparator: niacin (ER) tablet;   Drug: Comparator: ezetimibe (+) simvastatin;   Drug: Comparator: Placebo to Niacin (ER)
13 Completed Safety and Efficacy Study Comparing ABT-335 in Combination With Atorvastatin and Ezetimibe to Atorvastatin in Combination With Ezetimibe in Subjects With Abnormal Lipid (Fat) Levels in the Blood
Conditions: Dyslipidemias;   Coronary Heart Disease;   Combined (Atherogenic) Dyslipidemia;   Mixed Dyslipidemia
Interventions: Drug: ABT-335;   Drug: placebo;   Drug: atorvastatin;   Drug: ezetimibe
14 Completed Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With High Cholesterol (P03434)
Conditions: Hypercholesterolemia;   Atherosclerosis
Interventions: Drug: Ezetimibe + Atorvastatin;   Drug: Atorvastatin
15 Completed Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)(COMPLETED)
Conditions: Hypercholesterolaemia;   Atherosclerosis
Interventions: Drug: Ezetimibe + Simvastatin;   Drug: Simvastatin
16 Completed Effects of Ezetimibe on the Absorption of Oxidized Cholesterol
Condition: Hypercholesterolemia
Intervention: Drug: ezetimibe
17 Active, not recruiting Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression of Peripheral Arterial Disease (The ELIMIT Study)
Condition: Peripheral Arterial Disease
Interventions: Drug: Ezetimibe;   Drug: Niaspan;   Drug: Statin therapy;   Behavioral: Standard care;   Drug: Aspirin;   Drug: Clopidogrel;   Drug: Placebo Niaspan;   Drug: Placebo Ezetimibe;   Procedure: Percutaneous transluminal angioplasty (PTA)
18 Completed Effect Of Ezetimibe Coadministration With Simvastatin In A Middle Eastern Population: A Prospective, Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial
Condition: Hypercholesterolemia
Interventions: Drug: ezetimibe;   Drug: simvastatin;   Drug: Placebo (Unspecified)
19 Terminated Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)(TERMINATED)
Conditions: Hypercholesterolemia;   Atherosclerosis
Interventions: Drug: Ezetimibe;   Drug: Placebo
20 Completed Higher-Dose Ezetimibe to Treat Homozygous Sitosterolemia
Conditions: Heart Diseases;   Metabolism, Inborn Errors
Interventions: Drug: SCH-58235;   Drug: Ezetimibe

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