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Volume 4(8);  August 2007
Editorial
Qualitative Research: Understanding Patients' Needs and Experiences
The PLoS Medicine Editors
PLoS Med. 2007 August; 4(8): e258. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040258.
PMCID: PMC1952201
Neglected Diseases
Anaemia: A Useful Indicator of Neglected Disease Burden and Control
Imelda Bates, Stephen McKew, and Faruk Sarkinfada
PLoS Med. 2007 August; 4(8): e231. Published online 2007 August 14. doi: 10.1371/journal.pmed.0040231.
PMCID: PMC1945036
Perspectives
Improving Case Definitions for Severe Malaria
Nicholas M Anstey and Ric N Price
PLoS Med. 2007 August; 4(8): e267. Published online 2007 August 21. doi: 10.1371/journal.pmed.0040267.
PMCID: PMC1949843
Health in Action
Creating a Conversation: Insights from the Development of a Decision Aid
Victor M Montori, Maggie Breslin, Matthew Maleska, and Audrey J Weymiller
PLoS Med. 2007 August; 4(8): e233. Published online 2007 August 7. doi: 10.1371/journal.pmed.0040233.
PMCID: PMC1939861
Development of New Tuberculosis Vaccines: A Global Perspective on Regulatory Issues
Michael J Brennan, Uli Fruth, Julie Milstien, Rosemary Tiernan, Sergio de Andrade Nishioka, Liliana Chocarro, and Developing Countries Vaccine Regulatory Network and the Ad Hoc Regulatory and TB Expert Panel
PLoS Med. 2007 August; 4(8): e252. Published online 2007 August 7. doi: 10.1371/journal.pmed.0040252.
PMCID: PMC1939860
Setting Priorities in Child Health Research Investments for South Africa
Mark Tomlinson, Mickey Chopra, David Sanders, Debbie Bradshaw, Michael Hendricks, David Greenfield, Robert E Black, Shams El Arifeen, and Igor Rudan
PLoS Med. 2007 August; 4(8): e259. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040259.
PMCID: PMC1952202
Policy Forum
Making Performance-Based Funding Work for Health
Daniel Low-Beer, Houtan Afkhami, Ryuichi Komatsu, Prerna Banati, Musoke Sempala, Itamar Katz, John Cutler, Paul Schumacher, Ronald Tran-Ba-Huy, and Bernhard Schwartländer
PLoS Med. 2007 August; 4(8): e219. Published online 2007 August 21. doi: 10.1371/journal.pmed.0040219.
PMCID: PMC1949844
HIV Denial in the Internet Era
Tara C Smith and Steven P Novella
PLoS Med. 2007 August; 4(8): e256. Published online 2007 August 21. doi: 10.1371/journal.pmed.0040256.
PMCID: PMC1949841
Research in Translation
Translating Pharmacogenomics: Challenges on the Road to the Clinic
Jesse J Swen, Tom W Huizinga, Hans Gelderblom, Elisabeth G. E de Vries, Willem J. J Assendelft, Julia Kirchheiner, and Henk-Jan Guchelaar
PLoS Med. 2007 August; 4(8): e209. Published online 2007 August 14. doi: 10.1371/journal.pmed.0040209.
PMCID: PMC1945038
Research Articles
Monitoring the Impact of Influenza by Age: Emergency Department Fever and Respiratory Complaint Surveillance in New York City
Donald R Olson, Richard T Heffernan, Marc Paladini, Kevin Konty, Don Weiss, and Farzad Mostashari
PLoS Med. 2007 August; 4(8): e247. Published online 2007 August 7. doi: 10.1371/journal.pmed.0040247.
PMCID: PMC1939858
How Evidence-Based Are the Recommendations in Evidence-Based Guidelines?
Finlay A McAlister, Sean van Diepen, Rajdeep S Padwal, Jeffrey A Johnson, and Sumit R Majumdar
PLoS Med. 2007 August; 4(8): e250. Published online 2007 August 7. doi: 10.1371/journal.pmed.0040250.
PMCID: PMC1939859
Defining Childhood Severe Falciparum Malaria for Intervention Studies
Philip Bejon, James A Berkley, Tabitha Mwangi, Edna Ogada, Isaiah Mwangi, Kathryn Maitland, Thomas Williams, J. Anthony G Scott, Mike English, Brett S Lowe, Norbert Peshu, Charles R. J. C Newton, and Kevin Marsh
PLoS Med. 2007 August; 4(8): e251. Published online 2007 August 21. doi: 10.1371/journal.pmed.0040251.
PMCID: PMC1949845
Expansion of Regulatory T Cells in Patients with Langerhans Cell Histiocytosis
Brigitte Senechal, Gaelle Elain, Eric Jeziorski, Virginie Grondin, Natacha Patey-Mariaud de Serre, Francis Jaubert, Kheira Beldjord, Arielle Lellouch, Christophe Glorion, Michel Zerah, Pierre Mary, Mohammed Barkaoui, Jean Francois Emile, Liliane Boccon-Gibod, Patrice Josset, Marianne Debré, Alain Fischer, Jean Donadieu, and Frederic Geissmann
PLoS Med. 2007 August; 4(8): e253. Published online 2007 August 14. doi: 10.1371/journal.pmed.0040253.
PMCID: PMC1945037
Increasing Coverage and Decreasing Inequity in Insecticide-Treated Bed Net Use among Rural Kenyan Children
Abdisalan M Noor, Abdinasir A Amin, Willis S Akhwale, and Robert W Snow
PLoS Med. 2007 August; 4(8): e255. Published online 2007 August 21. doi: 10.1371/journal.pmed.0040255.
PMCID: PMC1949846
Antiretroviral Treatment and Prevention of Peripartum and Postnatal HIV Transmission in West Africa: Evaluation of a Two-Tiered Approach
Besigin Tonwe-Gold, Didier K Ekouevi, Ida Viho, Clarisse Amani-Bosse, Siaka Toure, Patrick A Coffie, François Rouet, Renaud Becquet, Valériane Leroy, Wafaa M El-Sadr, Elaine J Abrams, and François Dabis
PLoS Med. 2007 August; 4(8): e257. Published online 2007 August 21. doi: 10.1371/journal.pmed.0040257.
PMCID: PMC1949842
Whole Grain, Bran, and Germ Intake and Risk of Type 2 Diabetes: A Prospective Cohort Study and Systematic Review
Jeroen S. L de Munter, Frank B Hu, Donna Spiegelman, Mary Franz, and Rob M van Dam
PLoS Med. 2007 August; 4(8): e261. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040261.
PMCID: PMC1952203
Reducing Amyloid Plaque Burden via Ex Vivo Gene Delivery of an Aβ-Degrading Protease: A Novel Therapeutic Approach to Alzheimer Disease
Matthew L Hemming, Michaela Patterson, Casper Reske-Nielsen, Ling Lin, Ole Isacson, and Dennis J Selkoe
PLoS Med. 2007 August; 4(8): e262. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040262.
PMCID: PMC1952204
Independent Associations of Fasting Insulin, Glucose, and Glycated Haemoglobin with Stroke and Coronary Heart Disease in Older Women
Debbie A Lawlor, Abigail Fraser, Shah Ebrahim, and George Davey Smith
PLoS Med. 2007 August; 4(8): e263. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040263.
PMCID: PMC1952205
Corrections
Correction: Commercial Serological Antibody Detection Tests for the Diagnosis of Pulmonary Tuberculosis: A Systematic Review
Karen R Steingart, Megan Henry, Suman Laal, Philip C Hopewell, Andrew Ramsay, Dick Menzies, Jane Cunningham, Karin Weldingh, and Madhukar Pai
PLoS Med. 2007 August; 4(8): e254. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040254.
PMCID: PMC1952197
Corrects: Karen R Steingart, et al. Commercial Serological Antibody Detection Tests for the Diagnosis of Pulmonary Tuberculosis: A Systematic Review. PLoS Med. 2007 June; 4(6): e202.
Correction: Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target
Angela N Kuntz, Elisabeth Davioud-Charvet, Ahmed A Sayed, Lindsay L Califf, Jean Dessolin, Elias S. J Arnér, and David L Williams
PLoS Med. 2007 August; 4(8): e264. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040264.
PMCID: PMC1952206
Corrects: Angela N Kuntz, et al. Thioredoxin Glutathione Reductase from Schistosoma mansoni: An Essential Parasite Enzyme and a Key Drug Target. PLoS Med. 2007 June; 4(6): e206.
Correction: EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice
Alexei Shir, Manfred Ogris, Ernst Wagner, and Alexander Levitzki
PLoS Med. 2007 August; 4(8): e266. Published online 2007 August 28. doi: 10.1371/journal.pmed.0040266.
PMCID: PMC1952207
Corrects: Alexei Shir, et al. EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice. PLoS Med. 2006 January; 3(1): e6.
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