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Volume 5(4);  April 2008
Editorial
Better Reporting, Better Research: Guidelines and Guidance in PLoS Medicine
The PLoS Medicine Editors
PLoS Med. 2008 April; 5(4): e99. Published online 2008 April 29. doi: 10.1371/journal.pmed.0050099.
PMCID: PMC2346507
Perspectives
Exposure to War as a Risk Factor for Mental Disorders
David M Benedek and Robert J Ursano
PLoS Med. 2008 April; 5(4): e82. Published online 2008 April 1. doi: 10.1371/journal.pmed.0050082.
PMCID: PMC2276524
Quantifying the Importance of Interleukin-6 for Coronary Heart Disease
Bruce Neal
PLoS Med. 2008 April; 5(4): e84. Published online 2008 April 8. doi: 10.1371/journal.pmed.0050084.
PMCID: PMC2288621
A Blood Test for Lung Fibrosis
Peter J Barnes
PLoS Med. 2008 April; 5(4): e98. Published online 2008 April 29. doi: 10.1371/journal.pmed.0050098.
PMCID: PMC2346506
Standardising Outcomes in Paediatric Clinical Trials
Mike Clarke
PLoS Med. 2008 April; 5(4): e102. Published online 2008 April 29. doi: 10.1371/journal.pmed.0050102.
PMCID: PMC2346508
Health in Action
Progress in Vaccination against Haemophilus influenzae type b in the Americas
M. Carolina Danovaro-Holliday, Salvador Garcia, Ciro de Quadros, Gina Tambini, and Jon K Andrus
PLoS Med. 2008 April; 5(4): e87. Published online 2008 April 22. doi: 10.1371/journal.pmed.0050087.
PMCID: PMC2292748
Policy Forum
Chile's Neoliberal Health Reform: An Assessment and a Critique
Jean-Pierre Unger, Pierre De Paepe, Giorgio Solimano Cantuarias, and Oscar Arteaga Herrera
PLoS Med. 2008 April; 5(4): e79. Published online 2008 April 1. doi: 10.1371/journal.pmed.0050079.
PMCID: PMC2276520
Improving Defences at the Portal of HIV Entry: Mucosal and Innate Immunity: A summary report from a Global HIV Vaccine Enterprise Working Group
Robin J Shattock, Barton F Haynes, Bali Pulendran, Jorge Flores, José Esparza, and on behalf of a Working Group convened by the Global HIV Vaccine Enterprise
PLoS Med. 2008 April; 5(4): e81. Published online 2008 April 1. doi: 10.1371/journal.pmed.0050081.
PMCID: PMC2276525
What Are the Implications for Childhood Pneumonia of Successfully Introducing Hib and Pneumococcal Vaccines in Developing Countries?
J. Anthony G Scott and Mike English
PLoS Med. 2008 April; 5(4): e86. Published online 2008 April 22. doi: 10.1371/journal.pmed.0050086.
PMCID: PMC2292749
Research in Complex Humanitarian Emergencies: The Médecins Sans Frontières/epicentre Experience
Vincent Brown, Philippe J Guerin, Dominique Legros, Christophe Paquet, Bernard Pécoul, and Alain Moren
PLoS Med. 2008 April; 5(4): e89. Published online 2008 April 15. doi: 10.1371/journal.pmed.0050089.
PMCID: PMC2288622
Research Articles
Lifetime Prevalence of Mental Disorders in Lebanon: First Onset, Treatment, and Exposure to War
Elie G Karam, Zeina N Mneimneh, Hani Dimassi, John A Fayyad, Aimee N Karam, Soumana C Nasser, Somnath Chatterji, and Ronald C Kessler
PLoS Med. 2008 April; 5(4): e61. Published online 2008 April 1. doi: 10.1371/journal.pmed.0050061.
PMCID: PMC2276523
The Reversal of Fortunes: Trends in County Mortality and Cross-County Mortality Disparities in the United States
Majid Ezzati, Ari B Friedman, Sandeep C Kulkarni, and Christopher J. L Murray
PLoS Med. 2008 April; 5(4): e66. Published online 2008 April 22. doi: 10.1371/journal.pmed.0050066.
PMCID: PMC2323303
Cytological and Transcript Analyses Reveal Fat and Lazy Persister-Like Bacilli in Tuberculous Sputum
Natalie J Garton, Simon J Waddell, Anna L Sherratt, Su-Min Lee, Rebecca J Smith, Claire Senner, Jason Hinds, Kumar Rajakumar, Richard A Adegbola, Gurdyal S Besra, Philip D Butcher, and Michael R Barer
PLoS Med. 2008 April; 5(4): e75. Published online 2008 April 1. doi: 10.1371/journal.pmed.0050075.
PMCID: PMC2276522
A Randomised, Blinded, Placebo-Controlled Trial in Dementia Patients Continuing or Stopping Neuroleptics (The DART-AD Trial)
Clive Ballard, Marisa Margallo Lana, Megan Theodoulou, Simon Douglas, Rupert McShane, Robin Jacoby, Katja Kossakowski, Ly-Mee Yu, Edmund Juszczak, and on behalf of the Investigators DART AD
PLoS Med. 2008 April; 5(4): e76. Published online 2008 April 1. doi: 10.1371/journal.pmed.0050076.
PMCID: PMC2276521
Long-Term Interleukin-6 Levels and Subsequent Risk of Coronary Heart Disease: Two New Prospective Studies and a Systematic Review
John Danesh, Stephen Kaptoge, Andrea G Mann, Nadeem Sarwar, Angela Wood, Sara B Angleman, Frances Wensley, Julian P. T Higgins, Lucy Lennon, Gudny Eiriksdottir, Ann Rumley, Peter H Whincup, Gordon D. O Lowe, and Vilmundur Gudnason
PLoS Med. 2008 April; 5(4): e78. Published online 2008 April 8. doi: 10.1371/journal.pmed.0050078.
PMCID: PMC2288623
Estimating Incidence from Prevalence in Generalised HIV Epidemics: Methods and Validation
Timothy B Hallett, Basia Zaba, Jim Todd, Ben Lopman, Wambura Mwita, Sam Biraro, Simon Gregson, J. Ties Boerma, and on behalf of the ALPHA Network
PLoS Med. 2008 April; 5(4): e80. Published online 2008 April 8. doi: 10.1371/journal.pmed.0050080.
PMCID: PMC2288620
In Vivo Response to Methotrexate Forecasts Outcome of Acute Lymphoblastic Leukemia and Has a Distinct Gene Expression Profile
Michael J Sorich, Nicolas Pottier, Deqing Pei, Wenjian Yang, Leo Kager, Gabriele Stocco, Cheng Cheng, John C Panetta, Ching-Hon Pui, Mary V Relling, Meyling H Cheok, and William E Evans
PLoS Med. 2008 April; 5(4): e83. Published online 2008 April 15. doi: 10.1371/journal.pmed.0050083.
PMCID: PMC2292747
Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma
Kimberly A Kelly, Nabeel Bardeesy, Rajesh Anbazhagan, Sushma Gurumurthy, Justin Berger, Herlen Alencar, Ronald A DePinho, Umar Mahmood, and Ralph Weissleder
PLoS Med. 2008 April; 5(4): e85. Published online 2008 April 15. doi: 10.1371/journal.pmed.0050085.
PMCID: PMC2292750
Mutations in a Novel, Cryptic Exon of the Luteinizing Hormone/Chorionic Gonadotropin Receptor Gene Cause Male Pseudohermaphroditism
Nina Kossack, Manuela Simoni, Annette Richter-Unruh, Axel P. N Themmen, and Jörg Gromoll
PLoS Med. 2008 April; 5(4): e88. Published online 2008 April 22. doi: 10.1371/journal.pmed.0050088.
PMCID: PMC2323302
MMP1 and MMP7 as Potential Peripheral Blood Biomarkers in Idiopathic Pulmonary Fibrosis
Ivan O Rosas, Thomas J Richards, Kazuhisa Konishi, Yingze Zhang, Kevin Gibson, Anna E Lokshin, Kathleen O Lindell, Jose Cisneros, Sandra D MacDonald, Annie Pardo, Frank Sciurba, James Dauber, Moises Selman, Bernadette R Gochuico, and Naftali Kaminski
PLoS Med. 2008 April; 5(4): e93. Published online 2008 April 29. doi: 10.1371/journal.pmed.0050093.
PMCID: PMC2346504
A Systematic Review of Studies That Aim to Determine Which Outcomes to Measure in Clinical Trials in Children
Ian Sinha, Leanne Jones, Rosalind L Smyth, and Paula R Williamson
PLoS Med. 2008 April; 5(4): e96. Published online 2008 April 29. doi: 10.1371/journal.pmed.0050096.
PMCID: PMC2346505
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