Projects

GENOMIC AND IMMUNOLOGICAL ANALYSIS OF SPIROCHETE DISEASES Appropriated (D)   Accession Number: 411434

APPLIED GENOMIC ANALYSIS OF LEPTOSPIRA Nonfunded Cooperative Agreement (N)   Accession Number: 409242

IMMUNOLOGICAL RESPONSE OF CATTLE TO LEPTOSPIRA BORGPETERSENII SEROVAR HARDJO Trust (T)   Accession Number: 411688

Publications

Variable Nucleotide Tandem-Repeat Analysis Revealing a Unique Group of Leptospira interrogans Serovar Pomona Isolates Associated with California Sea Lions - (Peer Reviewed Journal)

Zuerner, R.L., Alt, D.P. 2009. Variable Nucleotide Tandem-Repeat Analysis Revealing a Unique Group of Leptospira interrogans Serovar Pomona Isolates Associated with California Sea Lions. Journal of Clinical Microbiology. 47(4):1202-1205.

Genus I. Leptospira - (Book/Chapter) - (29-Jan-09)

Family II. Leptospiraceae Hovind-Hougen 1979, 245AL - (Book/Chapter) - (29-Jan-09)

Genus II. Leptonema Hovind-Hougen 1983, 439AL - (Book/Chapter) - (29-Jan-09)

Genus III. Turneriella Levett, Morey, Galloway, Steigerwalt, Ellis 2005, 1497AL - (Book/Chapter) - (29-Jan-09)

Geographical dissemination of Leptospira interrogans serovar Pomona during seasonal migration of California sea lions - (Peer Reviewed Journal) - (17-Dec-08)

BVDV infection alters toll-like and TNF-alpha receptor signalling in bovine aortic endothelial cells - (Abstract)

Neill, J.D., Zuerner, R.L., Ridpath, J.F. 2009. BVDV Infection Alters Toll-Like and TNF-alpha Receptor Signalling in Bovine Aortic Endothelial Cells [abstract]. 4th U.S. BVDV Symposium. Paper No. 2-5.

Genetic Diversity of the Leptospiral Immunoglobulin-like (Lig) Genes in Pathogenic Leptospira spp. - (Peer Reviewed Journal)

Mcbride, A.J., Cerqueira, G.M., Suchard, M.A., Moreira, A.N., Zuerner, R.L., Reis, M.G., Haake, D.A., Ko, A.I., Dellagostin, O.A. 2009. Genetic Diversity of the Leptospiral Immunoglobulin-like (Lig) Genes in Pathogenic Leptospira spp.. Infection, Genetics and Evolution. 9(2):196-205.

Identification of a Divided Genome for VSH-1, the Prophage-Like Gene Transfer Agent of Brachyspira hyodysenteriae - (Peer Reviewed Journal)

Stanton, T.B., Humphrey, S.B., Bayles, D.O., Zuerner, R.L. 2008. Identification of a Divided Genome for VSH-1, the Prophage-Like Gene Transfer Agent of Brachyspira hyodysenteriae. Journal of Bacteriology. 191(5):1719-1721.

Conservation of the S10-spc-alpha Locus within Otherwise Highly Pastic Genomes Provides Phylogenetic Insight into the Genus Leptospira - (Peer Reviewed Journal)

Victoria, B., Ahmed, A., Zuerner, R.L., Ahmed, N., Bulach, D.M., Quinteiro, J., Hartskeerl, R.A. 2008. Conservation of the S10-spc-alpha Locus within Otherwise Highly Plastic Genomes Provides Phylogenetic Insight into the Genus Leptospira. PLoS One. 3(7):1-9. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0002752.

BHMP39 PROTEINS OF B. HYODYSENTERIAE FORM HIGH MOLECULAR WEIGHT COMPLEXES - (Abstract)

Witchell, T., Bulach, D., Hoke, D., Driesen, S., Stanton, T.B., Zuerner, R.L., Cordwell, S., Adler, B. 2008. Bhmp39 proteins of B. hyodysenteriae form high molecular weight complexes [abstract]. Australian Society for Microbiology. p.04.39.

Transcriptional Response of Leptospira interrogans to Different Iron Sources - (Abstract)

Lo, M., Ellis, K., Murray, G., Haake, D., Matsunaga, J., Zuerner, R.L., Adler, B. 2008. Transcriptional Response of Leptospira interrogans to Different Iron Sources [abstract]. GENOMES 2008: Functional Genomics of Microorganisms. Poster No. L16.

Detection of Pathogenic Leptospira Bacteria in Pinniped Populations via PCR and Identification of a Source of Transmission for Zoonotic Leptospirosis in the Marine Environment - (Peer Reviewed Journal)

Cameron, C.E., Zuerner, R.L., Raverty, S., Colegrove, K.M., Norman, S., Lambourn, D.M., Jeffries, S.J., Gulland, F.M. 2008. Detection of Pathogenic Leptospira Bacteria in Pinniped Populations via PCR and Identification of a Source of Transmission for Zoonotic Leptospirosis in the Marine Environment. Journal of Clinical Microbiology. 46(5):1728-1733.

COLLATERAL EFFECTS OF ANTIBIOTICS - CARBADOX AND METRONIDAZOLE INDUCE VSH-1 AND FACILITATE GENE TRANSFER AMONG BRACHYSPIRA HYODYSENTERIAE STRAINS - (Peer Reviewed Journal)

Stanton, T.B., Humphrey, S.B., Sharma, V.K., Zuerner, R.L. 2008. Collateral effects of antibiotics - carbadox and metronidazole induce VSH-1 and facilitate gene transfer among Brachyspira hyodysenteriae strains. Applied and Environmental Microbiology. 74(10):2950-2956.

Leptospira Protein Expression During Infection - (Abstract)

Zuerner, R.L. 2008. Leptospira Protein Expression During Infection [abstract]. Gordon Research Conference: Biology of Spirochetes. Poster No. 2-46.

Genome Sequence of the Saprophyte Leptospira Biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis - (Peer Reviewed Journal)

Picardeau, M., Bulach, D.M., Bouchier, C., Zuerner, R.L., Zidane, N., Wilson, P.J., Creno, S., Kuczek, E.S., Bommezzadri, S., Davis, J.C., Mcgrath, A., Roche, D., Johnson, M.J., Boursaux-Eude, C., Seemann, T., Rouy, Z., Coppel, R.L., Rood, J.I., Lajus, A., Davies, J.K., Medigue, C., Adler, B. 2008. Genome Sequence of the Saprophyte Leptospira Biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis. PLoS One. 3(2):e1607. Available: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0001607.

Bovine viral diarrhea virus infection alters global transcription profiles in bovine endothelial cells - (Peer Reviewed Journal)

Neill, J.D., Ridpath, J.F., Lange, A., Zuerner, R.L. 2008. Bovine Viral Diarrhoea Virus Infection Alters Global Transcription Profiles in Bovine Endothelial Cells. Developments in Biologicals (Basel). 132:93-98.

Whole-genome Sequencing of the Saprophyte L. biflexa and Comparative Genomics of Pathogoenic and Saprophytic Leptospira Species - (Abstract)

Picardeau, M., Bulach, D.M., Bouchier, C., Zuerner, R.L., Zidane, N., Wilson, P.J., Creno, S., Kuczek, E.S., Bommezzadri, S., Davis, J.C., Mcgrath, A., Roche, D., Johnson, M.J., Boursaux-Etude, C., Seemann, T., Rouy, Z., Coppel, R.L., Rood, J.I., Lajus, A., Davies, J.K., Medigue, C., Adler, B. 2007. Whole-genome Sequencing of the Saprophyte L. biflexa and Comparative Genomics of Pathogoenic and Saprophytic Leptospira Species [abstract]. International Leptospirosis Society. p. 114.

Lesion Formation and Antibody Response Induced by Papillomatous Digital Dermatitis-Associated Spirochetes in a Murine Abscess Model - (Peer Reviewed Journal)

Elliott, M.K., Alt, D.P., Zuerner, R.L. 2007. Lesion Formation and Antibody Response Induced by Papillomatous Digital Dermatitis (PDD)-associated spirochetes in a Murine Abscess Model. Infection and Immunity. 75(9):4400-4408.

Papillomatous Digital Dermatitis Spirochetes Suppress the Bovine Macrophage Innate Immune Response - (Peer Reviewed Journal)

Zuerner, R.L., Heidari, M., Elliott, M.K., Alt, D.P., Neill, J.D. 2007. Papillomatous Digital Dermatitis Spirochetes Suppress the Bovine Macrophage Innate Immune Response. Veterinary Microbiology. 125(2007):256-264.

BVD virus infection alters global transcription profiles in bovine endothelial cells - (Abstract)

Neill, J.D., Zuerner, R.L., Ridpath, J.F. 2007. BVD virus infection alters global transcription profiles in bovine endothelial cells [abstract]. International Symposium on Animal Genomics for Animal Health. Paper No. SA-020. p. 15.

INDUCTION AND TRANSCRIPTION OF VSH-1, A PROPHAGE-LIKE, GENE TRANSFER AGENT OF BRACHYSPIRA HYODYSENTERIAE - (Peer Reviewed Journal)

Matson, E.G., Zuerner, R.L., Stanton, T.B. 2007. Induction and transcription of VSH-1, a prophage-like, gene transfer agent of Brachyspira hyodysenteriae. Anaerobe. 13(2):89-97.

Response of Leptospira interrogans to Physiologic Osmolarity: Relevance in Signaling the Environment-to-Host Transition - (Peer Reviewed Journal)

Matsunaga, J., Lo, M., Bulach, D.M., Zuerner, R.L., Adler, B., Haake, D.A. 2007. Response of Leptospira interrogans to Physiologic Osmolarity: Relevance in Signaling the Environment-to-Host Transition. Infection and Immunity. 1175(6):2864-2874.

Genomics and vaccine development - (Peer Reviewed Journal)

Gay, C.G., Zuerner, R., Bannantine, J.P., Lillehoj, H.S., Zhu, J., Green, R.D., Pastoret, P.P. 2007. Genomics and vaccine development. OIE Rev. Sci Tech. 26:49-67.

LIPL45B IS A NOVEL, SURFACE-EXPOSED LIPOPROTEIN EXPRESSED DURING LEPTOSPIRAL DISSEMINATION IN THE MAMMALIAN HOST - (Peer Reviewed Journal)

Matsunaga, J., Wernied, K., Zuerner, R.L., Frank, A.T., Haake, D. 2006. Lipl45b is a Novel, Surface-exposed Lipoprotein Expressed during Leptospiral Dissemination in the Mammalian Host. Microbiology. 152:3777-3786.

Genome reduction in Leptospira borgpetersenii reflects limited transmission potential - (Peer Reviewed Journal)

Bulach, D., Zuerner, R.L., Wilson, P., Seemann, T., Mcgrath, A., Cullen, P., Davies, J., Kuczek, E., Alt, D.P., Peterson-Burch, B. 2006. Genome reduction in Leptospira borgpetersenii reflects limited transmission potential. Proceedings of the National Academy of Sciences. 103(39):14560-14565.

EFFECTS OF TEMPERATURE ON GENE EXPRESSION PATTERNS IN LEPTOSPIRA INTERROGANS SEROVAR LAI AS ASSESSED BY WHOLE-GENOME MICROARRAYS - (Peer Reviewed Journal)

Lo, M., Bulach, D.M., Powell, D.R., Haake, D.A., Matsunaga, J., Paustian, M., Zuerner, R.L., Adler, B. 2006. Effects of Temperature on Gene Expression Patterns in Leptospira interrogans Serovar Lai as Assessed by Whole-Genome Microarrays. Infection and Immunity. 74(10):5848-5859.

THE ORGANIZATION OF LEPTOSPIRA AT A GENOMIC LEVEL - (Book/Chapter)

Bulach, D., Seemann, T., Zuerner, R.L., Adler, B. 2006. The organization of leptospira at a genomic level. In: Chan, V.L., Sherman, P.M., Bourke, B., editors. Bacterial Genomes and Infectious Diseases. Totowa, USA: Humana Press. p. 109-123.

ANTIMICROBIAL COLLATERAL EFFECTS: INDUCTION OF THE PROPHAGE-LIKE, GENE TRANSFER AGENT VSH-1 IN CULTURES OF THE SWINE PATHOGEN BRACHYPSIRA HYODYSENTERIAE - (Abstract)

Stanton, T.B., Sharma, V.K., Humphrey, S.B., Zuerner, R.L. 2006. Antimicrobial collateral effects: Induction of the prophage-like, gene transfer agent VSH-1 in cultures of the swine pathogen Brachypsira hyodysenteriae [abstract]. American Society for Microbiology. May 20-26, 2006, Orlando, Florida. 2006 CDROM.

SEQUENCE CONSERVATION OF THE LEPTOSPIRAL IMMUNOGLOBULIN-LIKE (LIG) GENES AMONG PATHOGENIC LEPTOSPIRA SPP. - (Abstract)

Mcbride, A.J., Cerqueira, G., Medeiros, M., Zuerner, R.L., Reis, M.G., Haake, D., Ko, A.I., Dellagostin, O.A. 2006. Sequence conservation of the Leptospiral immunoglobulin-like (lig) genes among pathogenic Leptospira spp. [abstract]. Gordon Research Conference Proceedings. Paper No. M1.

Comparative Analysis of Pathogenic Leptospira Genomes - (Book/Chapter)

Zuerner, R.L., Bulach, D.M., Seemann, T., Coppel, R.L., Adler, B. 2006. Comparative Analysis of Pathogenic Leptospira Genomes. In: Cabello, F.C., et al., editors. Molecular Biology of Spirochetes. Amsterdam, Holland: IOS Press. p. 101-115.

COMPARATIVE GENOMICS OF PATHOGENIC LEPTOSPIRA - (Abstract)

Zuerner, R.L. 2005. Comparative genomics of pathogenic leptospira [abstract]. NATO Advanced Research Workshop, Molecular Biology of Spirochetes, 2005, National Institute of Public Health. p. 25.

THE VITAMIN K-DEPENDENT CARBOXYLASE HAS BEEN ACQUIRED AND ADAPTED BY LEPTOSPIRA PATHOGENS FOR A ROLE OTHER THAN PROTEIN CARBOXYLATION - (Peer Reviewed Journal)

Rishavy, M.A., Hallgren, K.W., Yakubenko, A.V., Zuerner, R.L., Runge, K.W., Berkner, K.L. 2005. The vitamin k-dependent carboxylase has been acquired and adapted by Leptospira pathogens for a role other than protein carboxylation. Journal of Biological Chemistry. 280(41):34870-7.

GENOME ANALYSIS OF PATHOGENIC LEPTOSPIRA - (Abstract)

Zuerner, R.L. 2005. Genome analysis of pathogenic leptospira [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. p. 86.

2004 LEPTOSPIROSIS OUTBREAK AMONGST CALIFORNIAN SEA LIONS - (Abstract)

Cullen, P.A., Gulland, F., Zuerner, R.L., Raverty, S., Lambourn, D., Cameron, C.E. 2005. 2004 Leptospirosis outbreak amongst Californian sea lions [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. p. 328.

THE GENOME OF LEPTOSPIRA BIFLEXA - (Abstract)

Bulach, D.M., Seemann, T., Mcgrath, A., Kuczek, E., Coppel, R.L., Davies, J.K., Rood, J.I., Alt, D.P., Zuerner, R.L., Adler, B. 2005. The genome of Leptospira biflexa [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. p. 136.

ANALYSIS OF THE EFFECTS OF TEMPERATURE SHIFTS ON LEPTOSPIRAL GENE EXPRESSION AS ASSESSED BY WHOLE GENOME MICROARRAY - (Abstract)

Lo, M., Bulach, D.M., Haake, D.A., Matsunaga, J., Paustian, M., Zuerner, R.L., Adler, B. 2005. Analysis of the effects of temperature shifts on leptospiral gene expression as assessed by whole genome microarray [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. p.143.

IDENTIFICATION OF GENES OF VSH-1, A PROPHAGE-LIKE GENE TRANSFER AGENT OF BRACHYSPIRA HYODYSENTERIAE - (Peer Reviewed Journal)

Matson, E.G., Thompson, M., Humphrey, S.B., Zuerner, R.L., Stanton, T.B. 2005. Identification of genes of VSH-1, a prophage-like gene transfer agent of Brachyspira hyodysenteriae. Journal of Bacteriology. 187(17):5885-5892.

IN VITRO SELECTED LEPTOSPIRA INTERROGANS SEROVAR POMONA ANTIGENIC VARIANTS HAVE NOVEL IS1501 TRANSPOSITIONS - (Peer Reviewed Journal)

Zuerner, R.L., Trueba, G. 2005. In vitro selected leptospira interrogans serovar pomona antigenic variants have novel is1501 transpositions. Federation of European Microbiological Societies Microbiology Letters. 248(2005):199-205.

LABORATORY MAINTENANCE OF PATHOGENIC LEPTOSPIRA - (Book/Chapter)

Zuerner, R.L. 2006. Laboratory maintenance of pathogenic leptospira. In: Coico, R., Kowalik, T., Quarles, J.M., Stevenson, B., Taylor, R.D., and Simon, A.E., editors. Current Protocols in Microbiology Vol. 1. Edison, NJ. John Wiley & Sons, Inc. p. 12E 1.1 - 12E 1.13.

INCURSION OF LEPTOSPIRA INTERROGANS, SEROVAR POMONA INTO THE PACIFIC NORTHWEST WITH MIGRATORY SUBADULT AND ADULT CALIFORNIA SEA LIONS (ZALOPHUS CALIFORNIANUS) - (Abstract)

Raverty, S., Lambourn, D., Cameron, C.E., Norman, S.A., Zuerner, R.L., Szaniszlo, W., Olesiuk, P., Gulland, F. 2005. Incursion of leptospira interrogans, serovar pomona into the pacific northwest with migratory subadult and adult california sea lions (zalophus californianus)[abstract]. Proceedings of the International Association for Aquatic Animal Medicine. p. 245.

VSH-1, A PROPHAGE-LIKE, GENE TRANSFER AGENT OF BRACHYSPIRA HYODYSENTERIAE AND (PROBABLY) OF OTHER BRACHYSPIRA SPECIES - (Abstract)

Stanton, T.B., Matson, E.G., Humphrey, S.B., Zuerner, R.L., Sharma, V.K. 2005. VSH-1, a prophage-like, gene transfer agent of Brachyspira hyodysenteriae and (probably) of other Brachyspira species [abstract]. Third International Conference on Colonic Spirochaetal Infections in Animals and Humans. p. 15-16.

COMPLETION OF THE GENOME SEQUENCE OF BRUCELLA ABORTUS AND COMPARISON TO THE HIGHLY SIMILAR GENOMES OF B. MELITENSIS AND B. SUIS - (Peer Reviewed Journal)

Halling, S.M., Peterson Burch, B.D., Bricker, B.J., Zuerner, R.L., Qing, Z., Li, L., Kapur, V., Alt, D.P., Olsen, S.C. 2005. Completion of the genome sequence of brucella abortus and comparison to the highly similar genomes of b. melitensis and b. suis. Journal of Bacteriology. 187(8):2715-26.

EXPERIMENTAL CANINE LEPTOSPIROSIS CAUSED BY LEPTOSPIRA INTERROGANS SEROVARS POMONA AND BRATISLAVA - (Peer Reviewed Journal)

Greenlee, J.J., Alt, D.P., Bolin, C.A., Zuerner, R.L., Andreasen, C.B. 2005. Experimental canine Leptospirosis caused by Leptospira interrogans serovars Pomona and Bratislava. American Journal of Veterinary Research. 66(10):1816-1822.

INFLUENCE OF THE SPIROVAC(R) LEPTOSPIROSIS VACCINE ON IMMUNOLOGIC RESPONSES OF BISON TO BRUCELLA ABORTUS STRAIN RB51 VACCINE - (Abstract)

Olsen, S.C., Stoffregen, W.C., Zuerner, R.L., Alt, D.P. 2004. Influence of the spirovac(r) leptospirosis vaccine on immunologic responses of bison to brucella abortus strain rb51 vaccine [abstract]. Research Workers in Animal Diseases Conference Proceedings. p.98.

ROLE OF HHA AND LER IN TRANSCRIPTIONAL REGULATION OF THE ESP OPERON OF ENTEROHEMORRHAGIC ESCHERICHIA COLI O157:H7 - (Peer Reviewed Journal)

Sharma, V.K., Zuerner, R.L. 2004. Role of hha and ler in transcriptional regulation of the esp operon of enterohemorrhagic Escherichia coli O157:H7. Journal of Bacteriology. 186(21):7290-7301.

EXPRESSION OF LEPTOSPIRAL IMMUNOGLOBULIN-LIKE PROTEIN FROM LEPTOSPIRA INTERROGANS AND EVALUATION OF ITS DIAGNOSTIC POTENTIAL IN A KINETIC ELISA - (Peer Reviewed Journal)

Palanaippan, R., Chang, Y., Hassan, F., Mcdonough, S., Pough, M., Barr, S., Simpson, K., Mohammad, H., Haake, D., Zuerner, R.L. 2004. Expression of leptospiral immunoglobulin-like protein from leptospira interrogans and evaluation of its diagnostic potential in kinetic ELISA. Journal of Medical Microbiology. 53(10):975-984.

GENETIC VARIATION IN BRACHYSPIRA: CHROMOSOMAL REARRANGEMENTS AND SEQUENCE DRIFT DISTINGUISH B. PILOSICOLI FROM B. HYODYSENTERIAE - (Peer Reviewed Journal)

Zuerner, R.L., Stanton, T.B., Minion, C., Li, C., Charon, N., Trott, D.J., Hampson, D. 2004. Genetic variation in Brachyspira: Chromosomal Rearrangements and Sequence Drift Distinguish B. pilosicoli from B. hyodysenteriae. Anaerobe 10 (2004): 229-237.

MOLECULAR EVOLUTION AND MOSAICISM OF LEPTOSPIRA OUTER MEMBRANE PROTEINS INVOLVES HORIZONTAL DNA TRANSFER - (Peer Reviewed Journal)

Haake, D.A., Suchard, M.A., Kelley, M.M., Dundoo, M., Alt, D.P., Zuerner, R.L. 2004. Molecular evolution and mosaicism of leptospira outer membrane proteins involves horizontal dna transfer. Journal of Bacteriology. 186(9):2818-2828.

CHARACTERISTICS OF VSH-1 GENE TRANSCRIPTION IN BRACHYSPIRA HYODYSENTERIAE - (Abstract)

MATSON, E.G., HUMPHREY, S.B., ZUERNER, R.L., STANTON, T.B. CHARACTERISTICS OF VSH-1 GENE TRANSCRIPTION IN BRACHYSPIRA HYODYSENTERIAE. PROCEEDINGS OF THE GORDON RESEARCH CONFERENCE. 2004. P. 2.

SAGE ANALYSIS OF BOVINE MACROPHAGES: IDENTIFICATION OF GENES TARGETED FOR IMMUNE SUPPRESSION BY DIGITAL DERMATITIS SPIROCHETES - (Proceedings/Symposium)

Heidari, M., Zuerner, R.L., Alt, D.P., Neill, J.D. 2004. Sage analysis of bovine macrophages: identification of genes targeted for immune suppression by digital dermatitis spirochetes. Gordon Research Conference Proceedings. p. 20.

IDENTIFICATION AND CLONING OF THE GENE ENCODING BMPC: AN OUTER MEMBRANE LIPOPROTEIN ASSOCIATED WITH BRACHYSPIRA PILOSICOLI MEMBRANE VESICLES - (Peer Reviewed Journal)

Trott, D.J., Alt, D.P., Zuerner, R.L., Bulach, D.M., Wannemuehler, M.J., Stasko, J.A., Townsend, K.M., Stanton, T.B. 2004. Identification and cloning of the gene encoding BmpC: an outer membrane lipoprotein associated with Brachyspira pilosicoli membrane vesicles. Microbiology. 150 (Pt 4):1041-1053.

CHARACTERIZATION OF SPHINGOMYELINASE-LIKE GENES IN LEPTOSPIRA BORGPETERSENII SEROVAR HARDJO - (Abstract) - (18-Sep-03)

CHARACTERIZATION OF TREPONEMA-PHAGEDENIS-LIKE SPIROCHETES ISOLATED FROM PAPILLOMATOUS DIGITAL DERMATITIS LESIONS IN DAIRY CATTLE - (Peer Reviewed Journal)

Trott, D.J., Moeller, M.R., Zuerner, R.L., Goff, J.P., Waters, W.R., Alt, D.P., Walker, R.L., Wannemuehler, M.J. 2003. Characterization of treponema-phagedenis-like spirochetes isolated from papillomatous digital dermatitis lesions in dairy cattle. Infection and Immunity.

COMPARATIVE ANALYSIS OF BRACHYSPIRA GENOMES (2ND INTERNATIONAL CONFERENCE ON COLONIC SPIROCHAETAL INFECTIONS IN ANIMALS AND HUMANS) - (Abstract)

Zuerner, R.L. 2003. Comparative analysis of brachyspira genomes [abstract]. 2nd international conference on colonic spirochaetal infections in animals and humans. pg. 25.

LIPL21 IS A NOVEL SURFACE EXPOSED LIPOPROTEIN OF PATHOGENIC LEPTOSPIRA SPECIES - (Peer Reviewed Journal)

Cullen, P., Haake, D., Bulach, D., Zuerner, R.L., Adler, B. 2003. Lipl21 is a novel surface exposed lipoprotein of pathogenic leptospira species. Infection and Immunity.

GENOMIC SEQUENCE ANALYSIS OF LEPTOSPIRA BORGPETERSENII SEROVAR HARDJO - (Abstract)

Zuerner, R.L., Alt, D.P., Bulach, D., Adler, B., Cullen, P., Haake, D. 2002. Genomic sequence analysis of leptospira borgpetersenii serovar hardjo [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. pg. 32.

THE S10-SPC-ALPHA OPERON IS HIGHLY CONSERVED AMONG L. INTERROGANS SENSU STRICTO - (Abstract)

Victoria, B., Zuerner, R.L., Hartskeerl, R.A. 2002. The s10-spc-alpha operon is highly conserved among l. interrogans sensu stricto [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. pg. 75.

IDENTIFICATION AND CHARACTERIZATION OF A NOVEL LEPTOSPIRAL 'MINI-MOMP' - (Abstract)

Cullen, P.A., Haake, D., Bulach, D.M., Zuerner, R.L., Adler, B. 2002. Identification and characterization of a novel leptospiral 'mini-momp' [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. pg. 27.

SEQUENCING AND PRELIMINARY ANALYSIS OF THE GENOME OF LEPTOSPIRA BORGPETERSENII SEROVAR HARDJOBOVIS - (Abstract)

Bulach, D., Wilson, P., Mcgrath, A., Kuczek, E., Coppel, R., Davies, J., Rood, J., Zuerner, R.L., Adler, B. 2002. Sequencing and preliminary analysis of the genome of leptospira borgpetersenii serovar hardjobovis [abstract]. International Leptospirosis Society Meeting Abstracts and Proceedings. p. 33.

EVALUATION OF TYPE 1 IMMUNE RESPONSE IN NAIVE AND VACCINATED ANIMALS FOLLOWING CHALLENGE WITH LEPTOSPIRA BORGPETERSENII SEROVAR HARDJO: INVOLVEMENT OF WC1**+ GAMMA DELTA AND CD4 T CELLS - (Peer Reviewed Journal)

Naiman, B., Blumerman, S., Alt, D.P., Bolin, C., Brown, R., Zuerner, R.L., Baldwin, C. 2002. Evaluation of type 1 immune response in naive and vaccinated animals following challenge with leptospira borgpetersenii serovar hardjo: involvement of wc1**+ gamma delta and cd4 t cells. Infection and Immunity. 70(11)6147-57.