-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 TpHhapf3VfCO2FQp4+L/4DXs/Hp+k8f1PV+t3MPvo8DBKyooNmKoLeKlryN4tB2n
 Exs6aW97xjfugzwLQUGG5Q==

<SEC-DOCUMENT>0001193805-09-000615.txt : 20090317
<SEC-HEADER>0001193805-09-000615.hdr.sgml : 20090317
<ACCEPTANCE-DATETIME>20090317181631
ACCESSION NUMBER:		0001193805-09-000615
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20090130
FILED AS OF DATE:		20090317
DATE AS OF CHANGE:		20090317

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			QLT INC/BC
		CENTRAL INDEX KEY:			0000827809
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			A1
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		887 GREAT NORTHERN WAY
		STREET 2:		-
		CITY:			VANCOUVER
		STATE:			A1
		ZIP:			V5T 4T5
		BUSINESS PHONE:		6047077000

	MAIL ADDRESS:	
		STREET 1:		887 GREAT NORTHERN WAY
		CITY:			VANCOUVER
		STATE:			A1
		ZIP:			V5T 4T5

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	QLT PHOTO THERAPEUTICS INC
		DATE OF NAME CHANGE:	19960618

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	QUADRA LOGIC TECHNOLOGIES INC
		DATE OF NAME CHANGE:	19941201

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RENAISSANCE TECHNOLOGIES LLC
		CENTRAL INDEX KEY:			0001037389
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-17082
		FILM NUMBER:		09689283

	BUSINESS ADDRESS:	
		STREET 1:		800 THIRD AVE 33TH FL
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		2124866780

	MAIL ADDRESS:	
		STREET 1:		800 THIRD AVE 33RD FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022

	FORMER NAME:	
		FORMER CONFORMED NAME:	RENAISSANCE TECHNOLOGIES CORP
		DATE OF NAME CHANGE:	19990324

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SIMONS JAMES H
		CENTRAL INDEX KEY:			0000941976
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-17082
		FILM NUMBER:		09689282

	MAIL ADDRESS:	
		STREET 1:		RENAISSANCE TECHNOLOGIES LLC
		STREET 2:		800 THIRD AVE
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>e605177_ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0203</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2009-01-30</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000827809</issuerCik>
        <issuerName>QLT INC/BC</issuerName>
        <issuerTradingSymbol>QLTI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000941976</rptOwnerCik>
            <rptOwnerName>SIMONS JAMES H</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>RENAISSANCE TECHNOLOGIES LLC</rptOwnerStreet1>
            <rptOwnerStreet2>800 THIRD AVE</rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Please see footnote (1)</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001037389</rptOwnerCik>
            <rptOwnerName>RENAISSANCE TECHNOLOGIES LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>800 THIRD AVE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10022</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>Please see footnote (1)</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>182130</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>169290</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1314</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4920153</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>349800</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>59000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F7"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>5800</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F8"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Shares</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>100</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>See Footnote</value>
                    <footnoteId id="F9"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">This Form 3 is being filed by the undersigned as well as the entity listed on the Joint Filer Information Statement attached
 as an exhibit hereto (the &quot;Reporting Persons&quot;).  Neither the filing nor the execution of this statement shall be deemed an
 admission that either of the Reporting Persons are beneficial owners of any of the securities reported herein for purposes
 of Section 16 of the Securities Exchange Act of 1934 (the &quot;Exchange Act&quot;) or that either of the Reporting Persons are
 obligated to file this statement under Section 16 of the Exchange Act.  In any event, each of the Reporting Persons
 expressly disclaims beneficial ownership of the securities reported herein under Section 16 to the extent above such
 Reporting Person's pecuniary interest therein.</footnote>
        <footnote id="F2">Deutsche Bank AG, through an institutional account managed by Renaissance Technologies LLC (&quot;Renaissance&quot;).</footnote>
        <footnote id="F3">Palomino Ltd., which maintains an institutional account managed by Renaissance.</footnote>
        <footnote id="F4">Rock Creek MB, LLC, a trading subsidiary of certain Renaissance funds that is managed by Renaissance.</footnote>
        <footnote id="F5">RIEF Trading LLC, a trading subsidiary of certain Renaissance funds that is managed by Renaissance.</footnote>
        <footnote id="F6">RIEF RMP LLC, a fund managed by Renaissance.</footnote>
        <footnote id="F7">SGAM AI Equity Fund, a fund for which Renaissance provides investment management services.</footnote>
        <footnote id="F8">GF Trading LLC, a trading subsidiary of a Renaissance fund that is managed by Renaissance.</footnote>
        <footnote id="F9">Bear Stearns Equity Strategies RT LLC, which maintains an institutional account that is managed by Renaissance.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ James H. Simons</signatureName>
        <signatureDate>2009-03-17</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99
<SEQUENCE>2
<FILENAME>e605177_ex99.txt
<TEXT>

                             Joint Filer Information

Names:                             James H. Simons, Renaissance Technologies LLC

Address:                           800 Third Avenue
                                   New York, N.Y. 10022

Designated Filer:                  James H. Simons

Issuer and Ticker Symbol:          QLT Inc. (QLTI)

Date of Event Requring Filing
Of  This Statement:                January 30, 2009

The undersigned, Renaissance Technologies LLC, is jointly filing the attached
Statement of Changes In Beneficial Ownership on Form 3 with James H. Simons with
respect to the beneficial ownership of securities of QLT INC.

Signature:

Renaissance Technologies LLC


By: /s/ Mark Silber
    -----------------------------------------
      Mark Silber, Executive Vice President
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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