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Maintenance Rituximab for Follicular Lymphoma

Azacitidine Improves Survival in MDS

Second Stem Cell Transplant Not Helpful in Myeloma
Axitinib (Ag 013736) As Second Line Therapy For Metastatic Renal Cell Cancer

Basic Trial Information
Trial Description
     Summary
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overPharmaceutical / IndustryA4061032
AXIS TRIAL, NCT00678392

Trial Description

Summary

The study is designed to demonstrate that axitinib (AG-013736) is superior to sorafenib in delaying tumor progression in patients with metastatic renal cell cancer after failure of one first line regimen.

Eligibility Criteria

Inclusion Criteria:

  • Histologically documented metastatic renal cell cancer with a component of clear cell histology.
  • Evidence of measurable disease
  • Must have failed one prior systemic first-line regimen for metastatic renal cell cancer

Exclusion Criteria:

  • Prior treatment for metastatic renal cell cancer with more that one systemic first line therapy
  • Major surgery less than 4 weeks or radiation less than 2 weeks of starting study drug

Trial Contact Information

Trial Lead Organizations/Sponsors

Pfizer Incorporated

Pfizer CT.gov Call CenterStudy Director

Pfizer Oncology Clinical Trial Information ServicePh: 1-877-369-9753
  Email: PfizerCancerTrials@emergingmed.com

Pfizer CT.gov Call CenterPh: 1-800-718-1021

Trial Sites

U.S.A.
California
  Encinitis
 Pfizer Investigational Site
  La Jolla
 Pfizer Investigational Site
  Los Angeles
 Pfizer Investigational Site
  San Diego
 Pfizer Investigational Site
Colorado
  Aurora
 Pfizer Investigational Site
  Boulder
 Pfizer Investigational Site
  Colorado Springs
 Pfizer Investigational Site
  Denver
 Pfizer Investigational Site
  Lakewood
 Pfizer Investigational Site
  Littleton
 Pfizer Investigational Site
  Lone Tree
 Pfizer Investigational Site
  Longmont
 Pfizer Investigational Site
  Parker
 Pfizer Investigational Site
  Thornton
 Pfizer Investigational Site
District of Columbia
  Washington
 Pfizer Investigational Site
Florida
  Bonita Springs
 Pfizer Investigational Site
  Bradenton
 Pfizer Investigational Site
  Cape Coral
 Pfizer Investigational Site
  Deerfield Beach
 Pfizer Investigational Site
  Englewood
 Pfizer Investigational Site
  Fort Myers
 Pfizer Investigational Site
  Miami
 Pfizer Investigational Site
  Naples
 Pfizer Investigational Site
  Orlando
 Pfizer Investigational Site
  Port Charlotte
 Pfizer Investigational Site
  Sarasota
 Pfizer Investigational Site
  Venice
 Pfizer Investigational Site
Georgia
  Atlanta
 Pfizer Investigational Site
  Ringgold
 Pfizer Investigational Site
Idaho
  Boise
 Pfizer Investigational Site
  Fruitland
 Pfizer Investigational Site
  Meridian
 Pfizer Investigational Site
  Nampa
 Pfizer Investigational Site
  Twin Falls
 Pfizer Investigational Site
Illinois
  Maywood
 Pfizer Investigational Site
Indiana
  Carmel
 Pfizer Investigational Site
  Fishers
 Pfizer Investigational Site
  Greenfield
 Pfizer Investigational Site
  Indianapolis
 Pfizer Investigational Site
Kentucky
  Crestview Hills
 Pfizer Investigational Site
  Louisville
 Pfizer Investigational Site
  Paducah
 Pfizer Investigational Site
Massachusetts
  Boston
 Pfizer Investigational Site
Michigan
  Ann Arbor
 Pfizer Investigational Site
  Detroit
 Pfizer Investigational Site
  Farmington Hills
 Pfizer Investigational Site
Minnesota
  Minneapolis
 Pfizer Investigational Site
Missouri
  Columbia
 Pfizer Investigational Site
  St. Louis
 Pfizer Investigational Site
Nebraska
  Omaha
 Pfizer Investigational Site
Nevada
  Henderson
 Pfizer Investigational Site
  Las Vegas
 Pfizer Investigational Site
New Jersey
  Hackensack
 Pfizer Investigational Site
New York
  New York
 Pfizer Investigational Site
  Oneida
 Pfizer Investigational Site
  Oswego
 Pfizer Investigational Site
  Stony Brook
 Pfizer Investigational Site
  Syracuse
 Pfizer Investigational Site
North Carolina
  Cary
 Pfizer Investigational Site
  Durham
 Pfizer Investigational Site
  Raleigh
 Pfizer Investigational Site
Ohio
  Cincinnati
 Pfizer Investigational Site
  Cleveland
 Pfizer Investigational Site
  Dayton
 Pfizer Investigational Site
  Fairfield
 Pfizer Investigational Site
  Hamilton
 Pfizer Investigational Site
  Kettering
 Pfizer Investigational Site
  Wilmington
 Pfizer Investigational Site
Oklahoma
  Norman
 Pfizer Investigational Site
  Oklahoma City
 Pfizer Investigational Site
Oregon
  Eugene
 Pfizer Investigational Site
  Springfield
 Pfizer Investigational Site
Pennsylvania
  Allentown
 Pfizer Investigational Site
  Bethlehem
 Pfizer Investigational Site
  Hershey
 Pfizer Investigational Site
South Carolina
  Charleston
 Pfizer Investigational Site
  Easley
 Pfizer Investigational Site
  Greenville
 Pfizer Investigational Site
  Seneca
 Pfizer Investigational Site
  Spartanburg
 Pfizer Investigational Site
Tennessee
  Chattanooga
 Pfizer Investigational Site
  Crossville
 Pfizer Investigational Site
  Franklin
 Pfizer Investigational Site
  Gallatin
 Pfizer Investigational Site
  Germantown
 Pfizer Investigational Site
  Hermitage
 Pfizer Investigational Site
  Hixson
 Pfizer Investigational Site
  Knoxville
 Pfizer Investigational Site
  Lebanon
 Pfizer Investigational Site
  Murfreesboro
 Pfizer Investigational Site
  Nashville
 Pfizer Investigational Site
  Paris
 Pfizer Investigational Site
  Smyrna
 Pfizer Investigational Site
  Union City
 Pfizer Investigational Site
Texas
  Amarillo
 Pfizer Investigational Site
  Austin
 Pfizer Investigational Site
  Bedford
 Pfizer Investigational Site
  Dallas
 Pfizer Investigational Site
  Fort Worth
 Pfizer Investigational Site
  Fortworth
 Pfizer Investigational Site
  Lubbock
 Pfizer Investigational Site
  Round Rock
 Pfizer Investigational Site
  Tyler
 Pfizer Investigational Site
  Webster
 Pfizer Investigational Site
Virginia
  Arlington
 Pfizer Investigational Site
  Fairfax
 Pfizer Investigational Site
  Leesburg
 Pfizer Investigational Site
  Manassas
 Pfizer Investigational Site
  Mechanicsville
 Pfizer Investigational Site
  Midlothian
 Pfizer Investigational Site
  Norfolk
 Pfizer Investigational Site
  Richmond
 Pfizer Investigational Site
  Woodbridge
 Pfizer Investigational Site
Washington
  Seattle
 Pfizer Investigational Site
West Virginia
  Morgantown
 Pfizer Investigational Site
Australia
Australian Capital Territory
  Garran
 Pfizer Investigational Site
South Australia
  Ashford
 Pfizer Investigational Site
Victoria
  Ballarat
 Pfizer Investigational Site
  East Melbourne
 Pfizer Investigational Site
  Heidelberg
 Pfizer Investigational Site
  Heidelberg West
 Pfizer Investigational Site
Austria
  Wien
 Pfizer Investigational Site
Canada
Newfoundland and Labrador
  St. John's
 Pfizer Investigational Site
Ontario
  Oshawa
 Pfizer Investigational Site
France
  LYON
 Pfizer Investigational Site
  PARIS CEDEX 15
 Pfizer Investigational Site
  ST HERBLAIN CEDEX
 Pfizer Investigational Site
  Vandoeuvre les Nancy
 Pfizer Investigational Site
  VILLEJUIF CEDEX
 Pfizer Investigational Site
Germany
  Aachen
 Pfizer Investigational Site
  Berlin
 Pfizer Investigational Site
  Essen
 Pfizer Investigational Site
  Hannover
 Pfizer Investigational Site
  Muenchen
 Pfizer Investigational Site
Greece
  Athens
 Pfizer Investigational Site
India
  Kochi
 Pfizer Investigational Site
Italy
  Aviano (PN)
 Pfizer Investigational Site
  Genova
 Pfizer Investigational Site
  Milano
 Pfizer Investigational Site
  Pavia
 Pfizer Investigational Site
  Rozzano (MI)
 Pfizer Investigational Site
Poland
  Gdansk
 Pfizer Investigational Site
  Poznan
 Pfizer Investigational Site
  Warszawa
 Pfizer Investigational Site
Republic of Korea
  Busan
 Pfizer Investigational Site
  Goyang-si
 Pfizer Investigational Site
  Seoul
 Pfizer Investigational Site
Republic of Singapore
  Singapore
 Pfizer Investigational Site
Russia
  Moscow
 Pfizer Investigational Site
  Obninsk
 Pfizer Investigational Site
  St. Petersburg
 Pfizer Investigational Site
Spain
  L'HOSPITALET DE LLOBREGAT
 Pfizer Investigational Site
  MADRID
 Pfizer Investigational Site
  MALAGA
 Pfizer Investigational Site
  PAMPLONA
 Pfizer Investigational Site
  ZARAGOZA
 Pfizer Investigational Site
Sweden
  Linkoping
 Pfizer Investigational Site
  Umea
 Pfizer Investigational Site
  Vaxjo
 Pfizer Investigational Site
Taiwan, Province of China
  Taichung
 Pfizer Investigational Site
  Taoyun
 Pfizer Investigational Site
United Kingdom
  Birmingham
 Pfizer Investigational Site
  Northwood
 Pfizer Investigational Site

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT00678392
Information obtained from ClinicalTrials.gov on May 13, 2009

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.

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