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BCR-ABL fusion protein (... FYOO-zhun PRO-teen)

 A protein made from pieces of two genes that get joined together. It is found in most patients with chronic myelogenous leukemia (CML), and in some patients with acute lymphoblastic leukemia (ALL) or acute myelogenous leukemia (AML). Inside the leukemia cells, the ABL gene from chromosome 9 joins to the BCR gene on chromosome 22 to form the BCR-ABL fusion gene, which makes the BCR-ABL fusion protein.



Previous Definitions:BCG, BCG solution, bcl-2 antisense oligodeoxynucleotide G3139, BCL2, BCR-ABL fusion gene
Next Definitions:BCX-1777, BDC, BEACOPP, BEACOPP regimen, Beckwith-Wiedemann syndrome

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