Journal Publications, 2009
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April
Journal of Virology
Multiply-deleted replication-defective adenovirus vectors do not induce measurable vector-specific T cells in human trials.
Koup RA, Lamoreaux L, Zarkowsky D, Bailer RT, King CR, Gall JG, Brough DE, Graham BS, Roederer M.
J Virol. 2009 Apr 1.
Blood
Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV suppressive activity.
Almeida JR, Sauce D, Price DA, Papagno L, Shin SY, Moris A, Larsen M, Pancino G, Douek DC, Autran B, Saez-Cirion A, Appay V.
Blood. 2009 Apr 23.
Journal of Experimental Medicine
Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection.
Price DA, Asher TE, Wilson NA, Nason MC, Brenchley JM, Metzler IS, Venturi V, Gostick E, Chattopadhyay PK, Roederer M, Davenport MP, Watkins DI, Douek DC.
J Exp Med. 2009 Apr 13;206(4):923-36.
Journal of Immunology
Association of HIV-specific and total CD8+ T memory phenotypes in subtype C HIV-1 infection with viral set point.
Burgers WA, Riou C, Mlotshwa M, Maenetje P, de Assis Rosa D, Brenchley J, Mlisana K, Douek DC, Koup R, Roederer M, de Bruyn G, Karim SA, Williamson C, Gray CM; and the CAPRISA 002 Acute Infection Study Team.
J Immunol. 2009 Apr 15;182(8):4751-61.
Journal of Infectious Diseases
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-Treated HIV infection.
Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM.
J Infect Dis. 2009 Apr 15;199(8):1177-85.
Journal of Immunological Methods
A method for identification of HIV gp140 binding memory B cells in human blood.
Scheid JF, Mouquet H, Feldhahn N, Walker BD, Pereyra F, Cutrell E, Seaman MS, Mascola JR, Wyatt RT, Wardemann H, Nussenzweig MC.
J Immunol Methods. 2009 Apr 15;343(2):65-7.
March
Journal of Virology
Expanded breadth of the T-cell response to mosaic human immunodeficiency virus type 1 envelope DNA vaccination.
Kong WP, Wu L, Wallstrom TC, Fischer W, Yang ZY, Ko SY, Letvin NL, Haynes BF, Hahn BH, Korber B, Nabel GJ.
J Virol. 2009 Mar;83(5):2201-15.
Blood
High avidity myeloid leukemia-associated antigen-specific CD8+ T cells preferentially reside in the bone marrow.
Melenhorst JJ, Scheinberg P, Chattopadhyay PK, Gostick E, Ladell K, Roederer M, Hensel NF, Douek DC, Barrett AJ, Price DA.
Blood. 2009 Mar 5;113(10):2238-44.
Journal of Virology
Characterization of Respiratory Syncytial Virus M- and M2-Specific CD4 T Cells in a Murine Model.
Liu J, Ruckwardt TJ, Chen M, Johnson TR, Graham BS.
J Virol. 2009 Mar 4.
Journal of Virology
Enhanced Exposure of the CD4-Binding Site to Neutralizing Antibodies by Structural Design of a Membrane-Anchored HIV-1 gp120 Domain.
Wu L, Zhou T, Yang ZY, Svehla K, O'Dell S, Louder M, Xu L, Mascola JR, Burton DR, Hoxie J, Doms R, Kwong PD, Nabel GJ.
J Virol. 2009 Mar 4.
Journal of General Virology
Adenovirus Serotype 5 Infects Human Dendritic Cells via a CAR-Independent Receptor Pathway Mediated by Lactoferrin and DC-SIGN.
Adams WC, Bond E, Havenga MJ, Holterman L, Goudsmit J, Karlsson-Hedestam GB, Koup RA, Loré K.
J Gen Virol. 2009 Mar 12. [Epub ahead of print]
Nature
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals.
Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, Ott RG, Anthony RM, Zebroski H, Hurley A, Phogat A, Chakrabarti B, Li Y, Connors M, Pereyra F, Walker BD, Wardemann H, Ho D, Wyatt RT, Mascola JR, Ravetch JV, Nussenzweig MC.
Nature. 2009 Mar 15. [Epub ahead of print]
Virology
High titer HIV-1 V3-specific antibodies with broad reactivity but low neutralizing potency in acute infection and following vaccination.
Davis KL, Gray ES, Moore PL, Decker JM, Salomon A, Montefiori DC, Graham BS, Keefer MC, Pinter A, Morris L, Hahn BH, Shaw GM.
Virology. 2009 Mar 17 (epub).
February
Journal of Immunology
Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection.
Eberly MD, Kader M, Hassan W, Rogers KA, Zhou J, Mueller YM, Mattapallil MJ, Piatak M Jr, Lifson JD, Katsikis PD, Roederer M, Villinger F, Mattapallil JJ.
J Immunol. 2009 Feb 1;182(3):1439-48.
January
Journal of Virology
Regulatory T Cells Promote Early Influx of CD8+ T Cells in Lungs of Respiratory Syncytial Virus-Infected Mice and Diminish Immunodominance Disparities.
Ruckwardt TJ, Bonaparte KL, Nason MC, Graham BS.
J Virol.. 2009 Jan 19.
Journal of Virology
Partial protection of SIV-infected rhesus monkeys against superinfection with a heterologous SIV isolate.
Yeh WW, Jaru-Ampornpan P, Nevidomskyte D, Asmal M, Rao SS, Buzby AP, Montefiori DC, Korber BT, Letvin NL.
J Virol. 2009 Jan 7.
Journal of Leukocyte Biology
The cytolytic enzymes granyzme A, granzyme B, and perforin: expression patterns, cell distribution, and their relationship to cell maturity and bright CD57 expression.
Chattopadhyay PK, Betts MR, Price DA, Gostick E, Horton H, Roederer M, De Rosa SC.
J Leukoc Biol. 2009 Jan;85(1):88-97.
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