Paget's Disease of Bone (Print Version)

Also called: Also called: Osteitis deformans

Paget's disease of bone causes your bones to grow larger and weaker than normal. They also might break easily. The disease can lead to other health problems, too, such as arthritis and hearing loss. You can have Paget's disease in any bone, but it is most common in the spine, pelvis, skull and legs. The disease might affect one or several bones, but not your entire skeleton. More men than women have the disease. It is most common in older people.

Many people do not know they have Paget's disease because their symptoms are mild. For others, symptoms can include

Pain
Enlarged bones
Broken bones
Damaged cartilage in joints

No one knows what causes Paget's disease. In some cases, a virus might be responsible. It tends to run in families. You can treat Paget's disease with medicine and sometimes surgery. A good diet and exercise might also help.

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Start Here

Facts a New Patient Needs to Know about Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/default.asp
What Is Paget's Disease of Bone?(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/pagets_disease_ff.asp

Overviews

Information for Patients about Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/patient_info.asp
Also available in Spanish http://www.niams.nih.gov/Portal_En_Espanol/Informacion_de_Salud/Huesos/Pagets/default.asp
Paget's Disease of Bone(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/pagets-disease-of-bone/DS00485/METHOD=print&DSECTION=all
Paget's Disease of Bone(American College of Rheumatology) - http://www.rheumatology.org/public/factsheets/paget-disease.asp?aud=pat

Diagnosis/Symptoms

ALP (Alkaline Phosphatase) Test(American Association for Clinical Chemistry) - http://www.labtestsonline.org/understanding/analytes/alp/test.html
Bone Markers(American Association for Clinical Chemistry) - http://www.labtestsonline.org/understanding/analytes/bone_markers/glance.html
Bone Scan: Using Nuclear Medicine to Find Bone Abnormalities(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/bone-scan/CA00020/METHOD=print
How Is Paget's Disease of Bone Diagnosed?(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/diagnosed.asp

Treatment

Medical Treatment Decisions for People with Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/medical_treatment.asp

Related Issues

Paget's Disease of Bone and Osteoarthritis: Different Yet Related(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/pagets_osteoarthritis.asp
Pain and Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - Links to PDF - http://www.niams.nih.gov/Health_Info/Bone/Pagets/pain.pdf

Tutorials

Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://nihseniorhealth.gov/pagetsdiseaseofbone/toc.html

Clinical Trials

ClinicalTrials.gov: Osteitis Deformans(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Osteitis+Deformans%22

Genetics

Genetics and Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/Pagets/genetics.asp

Journal Articles

References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Article: Influence of musculoskeletal conditions on oral health among older adults. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18511715&tool=MedlinePlus
Article: Paget's disease and bisphosphonate-associated osteonecrosis of the jaws. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18486809&tool=MedlinePlus
Article: Elevated alkaline phosphatase: a diagnostic pearl for Paget's disease. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18422229&tool=MedlinePlus
Paget's Disease of Bone -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=osteitis+deformans[majr]+AND+humans[mh]+AND+english[la]&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus

Directories

Find an Orthopaedist(American Academy of Orthopaedic Surgeons) - http://www6.aaos.org/about/public/members.cfm

Organizations

National Institute of Arthritis and Musculoskeletal and Skin Diseases - http://www.niams.nih.gov/
Also available in Spanish http://www.niams.nih.gov/Portal_En_Espanol/
National Institutes of Health Osteoporosis and Related Bone Diseases~National Resource Center(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://www.niams.nih.gov/Health_Info/Bone/

Seniors

Paget's Disease of Bone(National Institute of Arthritis and Musculoskeletal and Skin Diseases) - http://nihseniorhealth.gov/pagetsdiseaseofbone/toc.html

You may also be interested in these MedlinePlus related pages:

Bones, Joints and Muscles - http://www.nlm.nih.gov/medlineplus/bonesjointsandmuscles.html

The primary NIH organization for research on Paget's Disease of Bone is the National Institute of Arthritis and Musculoskeletal and Skin Diseases - http://www.niams.nih.gov/